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Items: 1 to 50 of 74

1.

HIC1 links retinoic acid signalling to group 3 innate lymphoid cell-dependent regulation of intestinal immunity and homeostasis.

Burrows K, Antignano F, Chenery A, Bramhall M, Korinek V, Underhill TM, Zaph C.

PLoS Pathog. 2018 Feb 22;14(2):e1006869. doi: 10.1371/journal.ppat.1006869. eCollection 2018 Feb.

2.

Death by HDAC Inhibition in Synovial Sarcoma Cells.

Laporte AN, Poulin NM, Barrott JJ, Wang XQ, Lorzadeh A, Vander Werff R, Jones KB, Underhill TM, Nielsen TO.

Mol Cancer Ther. 2017 Dec;16(12):2656-2667. doi: 10.1158/1535-7163.MCT-17-0397. Epub 2017 Sep 6.

PMID:
28878027
3.

Methyltransferase G9A Regulates Osteogenesis via Twist Gene Repression.

Higashihori N, Lehnertz B, Sampaio A, Underhill TM, Rossi F, Richman JM.

J Dent Res. 2017 Sep;96(10):1136-1144. doi: 10.1177/0022034517716438. Epub 2017 Jun 23.

PMID:
28644763
4.

Regulation of Active DNA Demethylation through RAR-Mediated Recruitment of a TET/TDG Complex.

Hassan HM, Kolendowski B, Isovic M, Bose K, Dranse HJ, Sampaio AV, Underhill TM, Torchia J.

Cell Rep. 2017 May 23;19(8):1685-1697. doi: 10.1016/j.celrep.2017.05.007.

5.

The transcriptional repressor HIC1 regulates intestinal immune homeostasis.

Burrows K, Antignano F, Bramhall M, Chenery A, Scheer S, Korinek V, Underhill TM, Zaph C.

Mucosal Immunol. 2017 Nov;10(6):1518-1528. doi: 10.1038/mi.2017.17. Epub 2017 Mar 22.

PMID:
28327618
6.

Tumor-homing cytotoxic human induced neural stem cells for cancer therapy.

Bagó JR, Okolie O, Dumitru R, Ewend MG, Parker JS, Werff RV, Underhill TM, Schmid RS, Miller CR, Hingtgen SD.

Sci Transl Med. 2017 Feb 1;9(375). pii: eaah6510. doi: 10.1126/scitranslmed.aah6510.

PMID:
28148846
7.

HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma.

Laporte AN, Barrott JJ, Yao RJ, Poulin NM, Brodin BA, Jones KB, Underhill TM, Nielsen TO.

PLoS One. 2017 Jan 5;12(1):e0169407. doi: 10.1371/journal.pone.0169407. eCollection 2017.

8.

Methods and Strategies for Lineage Tracing of Mesenchymal Progenitor Cells.

Scott RW, Underhill TM.

Methods Mol Biol. 2016;1416:171-203. doi: 10.1007/978-1-4939-3584-0_10.

PMID:
27236672
9.

Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice.

Chow LN, Schreiner P, Ng BY, Lo B, Hughes MR, Scott RW, Gusti V, Lecour S, Simonson E, Manisali I, Barta I, McNagny KM, Crawford J, Webb M, Underhill TM.

PLoS One. 2016 Mar 21;11(3):e0151765. doi: 10.1371/journal.pone.0151765. eCollection 2016.

10.

Retinoid regulation of antiviral innate immunity in hepatocytes.

Cho NE, Bang BR, Gurung P, Li M, Clemens DL, Underhill TM, James LP, Chase JR, Saito T.

Hepatology. 2016 Jun;63(6):1783-95. doi: 10.1002/hep.28380. Epub 2016 Jan 21.

11.

SOX9 modulates the expression of key transcription factors required for heart valve development.

Garside VC, Cullum R, Alder O, Lu DY, Vander Werff R, Bilenky M, Zhao Y, Jones SJ, Marra MA, Underhill TM, Hoodless PA.

Development. 2015 Dec 15;142(24):4340-50. doi: 10.1242/dev.125252. Epub 2015 Nov 2.

12.

Two novel disease-causing variants in BMPR1B are associated with brachydactyly type A1.

Racacho L, Byrnes AM, MacDonald H, Dranse HJ, Nikkel SM, Allanson J, Rosser E, Underhill TM, Bulman DE.

Eur J Hum Genet. 2015 Dec;23(12):1640-5. doi: 10.1038/ejhg.2015.38. Epub 2015 Mar 11.

13.

The methyltransferase G9a regulates HoxA9-dependent transcription in AML.

Lehnertz B, Pabst C, Su L, Miller M, Liu F, Yi L, Zhang R, Krosl J, Yung E, Kirschner J, Rosten P, Underhill TM, Jin J, Hébert J, Sauvageau G, Humphries RK, Rossi FM.

Genes Dev. 2014 Feb 15;28(4):317-27. doi: 10.1101/gad.236794.113.

14.

Analysis of chondrogenesis using micromass cultures of limb mesenchyme.

Underhill TM, Dranse HJ, Hoffman LM.

Methods Mol Biol. 2014;1130:251-265. doi: 10.1007/978-1-62703-989-5_19.

PMID:
24482179
15.

The retinoic acid-metabolizing enzyme Cyp26b1 regulates CD4 T cell differentiation and function.

Chenery A, Burrows K, Antignano F, Underhill TM, Petkovich M, Zaph C.

PLoS One. 2013 Aug 22;8(8):e72308. doi: 10.1371/journal.pone.0072308. eCollection 2013.

16.

SS18-SSX2 and the mitochondrial apoptosis pathway in mouse and human synovial sarcomas.

Jones KB, Su L, Jin H, Lenz C, Randall RL, Underhill TM, Nielsen TO, Sharma S, Capecchi MR.

Oncogene. 2013 May 2;32(18):2365-71, 2375.e1-5. doi: 10.1038/onc.2012.247. Epub 2012 Jul 16.

17.

Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics.

Su L, Sampaio AV, Jones KB, Pacheco M, Goytain A, Lin S, Poulin N, Yi L, Rossi FM, Kast J, Capecchi MR, Underhill TM, Nielsen TO.

Cancer Cell. 2012 Mar 20;21(3):333-47. doi: 10.1016/j.ccr.2012.01.010.

18.

Functionally convergent white adipogenic progenitors of different lineages participate in a diffused system supporting tissue regeneration.

Lemos DR, Paylor B, Chang C, Sampaio A, Underhill TM, Rossi FM.

Stem Cells. 2012 Jun;30(6):1152-62. doi: 10.1002/stem.1082.

19.

Pannexin 3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes.

Bond SR, Lau A, Penuela S, Sampaio AV, Underhill TM, Laird DW, Naus CC.

J Bone Miner Res. 2011 Dec;26(12):2911-22. doi: 10.1002/jbmr.509.

20.

Genetic deletion of Cyp26b1 negatively impacts limb skeletogenesis by inhibiting chondrogenesis.

Dranse HJ, Sampaio AV, Petkovich M, Underhill TM.

J Cell Sci. 2011 Aug 15;124(Pt 16):2723-34. doi: 10.1242/jcs.084699.

21.

Mechanical force modulates scleraxis expression in bioartificial tendons.

Scott A, Danielson P, Abraham T, Fong G, Sampaio AV, Underhill TM.

J Musculoskelet Neuronal Interact. 2011 Jun;11(2):124-32.

22.

Scleraxis expression is coordinately regulated in a murine model of patellar tendon injury.

Scott A, Sampaio A, Abraham T, Duronio C, Underhill TM.

J Orthop Res. 2011 Feb;29(2):289-96. doi: 10.1002/jor.21220. Epub 2010 Aug 25.

23.

Mutations in GDF5 presenting as semidominant brachydactyly A1.

Byrnes AM, Racacho L, Nikkel SM, Xiao F, MacDonald H, Underhill TM, Bulman DE.

Hum Mutat. 2010 Oct;31(10):1155-62. doi: 10.1002/humu.21338.

PMID:
20683927
24.

EGR1 reactivation by histone deacetylase inhibitors promotes synovial sarcoma cell death through the PTEN tumor suppressor.

Su L, Cheng H, Sampaio AV, Nielsen TO, Underhill TM.

Oncogene. 2010 Jul 29;29(30):4352-61. doi: 10.1038/onc.2010.204. Epub 2010 May 31.

PMID:
20514024
25.

Regulation of BMP-dependent chondrogenesis in early limb mesenchyme by TGFbeta signals.

Karamboulas K, Dranse HJ, Underhill TM.

J Cell Sci. 2010 Jun 15;123(Pt 12):2068-76. doi: 10.1242/jcs.062901. Epub 2010 May 25.

26.

Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells.

Shankar J, Messenberg A, Chan J, Underhill TM, Foster LJ, Nabi IR.

Cancer Res. 2010 May 1;70(9):3780-90. doi: 10.1158/0008-5472.CAN-09-4439. Epub 2010 Apr 13.

27.

Genome-wide analyses of gene expression during mouse endochondral ossification.

James CG, Stanton LA, Agoston H, Ulici V, Underhill TM, Beier F.

PLoS One. 2010 Jan 13;5(1):e8693. doi: 10.1371/journal.pone.0008693.

28.

Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies.

Ye M, Berry-Wynne KM, Asai-Coakwell M, Sundaresan P, Footz T, French CR, Abitbol M, Fleisch VC, Corbett N, Allison WT, Drummond G, Walter MA, Underhill TM, Waskiewicz AJ, Lehmann OJ.

Hum Mol Genet. 2010 Jan 15;19(2):287-98. doi: 10.1093/hmg/ddp496. Epub 2009 Oct 28.

PMID:
19864492
29.

FRET reveals novel protein-receptor interaction of bone morphogenetic proteins receptors and adaptor protein 2 at the cell surface.

Bragdon B, Thinakaran S, Bonor J, Underhill TM, Petersen NO, Nohe A.

Biophys J. 2009 Sep 2;97(5):1428-35. doi: 10.1016/j.bpj.2009.05.061.

30.

In vivo micro-CT analysis of bone remodeling in a rat calvarial defect model.

Umoh JU, Sampaio AV, Welch I, Pitelka V, Goldberg HA, Underhill TM, Holdsworth DW.

Phys Med Biol. 2009 Apr 7;54(7):2147-61. doi: 10.1088/0031-9155/54/7/020. Epub 2009 Mar 13.

PMID:
19287088
31.

Noncanonical activation of Akt/protein kinase B in {beta}-cells by the incretin hormone glucose-dependent insulinotropic polypeptide.

Widenmaier SB, Sampaio AV, Underhill TM, McIntosh CH.

J Biol Chem. 2009 Apr 17;284(16):10764-73. doi: 10.1074/jbc.M809116200. Epub 2009 Feb 20.

32.

The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease.

Welch ID, Cowan MF, Beier F, Underhill TM.

Arthritis Res Ther. 2009;11(1):R14. doi: 10.1186/ar2604. Epub 2009 Jan 28.

33.

Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes.

Asai-Coakwell M, French CR, Ye M, Garcha K, Bigot K, Perera AG, Staehling-Hampton K, Mema SC, Chanda B, Mushegian A, Bamforth S, Doschak MR, Li G, Dobbs MB, Giampietro PF, Brooks BP, Vijayalakshmi P, Sauvé Y, Abitbol M, Sundaresan P, van Heyningen V, Pourquié O, Underhill TM, Waskiewicz AJ, Lehmann OJ.

Hum Mol Genet. 2009 Mar 15;18(6):1110-21. doi: 10.1093/hmg/ddp008. Epub 2009 Jan 6.

PMID:
19129173
34.

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

Luciani DS, Gwiazda KS, Yang TL, Kalynyak TB, Bychkivska Y, Frey MH, Jeffrey KD, Sampaio AV, Underhill TM, Johnson JD.

Diabetes. 2009 Feb;58(2):422-32. doi: 10.2337/db07-1762. Epub 2008 Nov 25.

35.

Localized Rho GTPase activation regulates RNA dynamics and compartmentalization in tumor cell protrusions.

Stuart HC, Jia Z, Messenberg A, Joshi B, Underhill TM, Moukhles H, Nabi IR.

J Biol Chem. 2008 Dec 12;283(50):34785-95. doi: 10.1074/jbc.M804014200. Epub 2008 Oct 9.

36.

Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen.

Noble BR, Babiuk RP, Clugston RD, Underhill TM, Sun H, Kawaguchi R, Walfish PG, Blomhoff R, Gundersen TE, Greer JJ.

Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L1079-87. Epub 2007 Aug 17.

37.
38.

Bone sialoprotein expression enhances osteoblast differentiation and matrix mineralization in vitro.

Gordon JA, Tye CE, Sampaio AV, Underhill TM, Hunter GK, Goldberg HA.

Bone. 2007 Sep;41(3):462-73. Epub 2007 May 6.

PMID:
17572166
39.
40.

BMP action in skeletogenesis involves attenuation of retinoid signaling.

Hoffman LM, Garcha K, Karamboulas K, Cowan MF, Drysdale LM, Horton WA, Underhill TM.

J Cell Biol. 2006 Jul 3;174(1):101-13.

41.

Microarray analyses of gene expression during chondrocyte differentiation identifies novel regulators of hypertrophy.

James CG, Appleton CT, Ulici V, Underhill TM, Beier F.

Mol Biol Cell. 2005 Nov;16(11):5316-33. Epub 2005 Aug 31.

42.

Dynamics and interaction of caveolin-1 isoforms with BMP-receptors.

Nohe A, Keating E, Underhill TM, Knaus P, Petersen NO.

J Cell Sci. 2005 Feb 1;118(Pt 3):643-50. Epub 2005 Jan 18.

43.

Identification of the putative collagen X gene from the pufferfish Fugu rubripes.

Woods A, James C, Underhill TM, Beier F; CIHR Group in Skeletal Development and Remodeling.

Gene. 2004 Nov 10;342(1):77-83.

PMID:
15573454
44.
45.

MAP kinases in chondrocyte differentiation.

Stanton LA, Underhill TM, Beier F.

Dev Biol. 2003 Nov 15;263(2):165-75. Review.

46.

p38 MAP kinase signalling is required for hypertrophic chondrocyte differentiation.

Stanton LA, Sabari S, Sampaio AV, Underhill TM, Beier F.

Biochem J. 2004 Feb 15;378(Pt 1):53-62.

47.

Revisiting the role of retinoid signaling in skeletal development.

Weston AD, Hoffman LM, Underhill TM.

Birth Defects Res C Embryo Today. 2003 May;69(2):156-73. Review.

PMID:
12955859
48.

Down-regulation of retinoic acid receptor alpha signaling is required for sacculation and type I cell formation in the developing lung.

Wongtrakool C, Malpel S, Gorenstein J, Sedita J, Ramirez MI, Underhill TM, Cardoso WV.

J Biol Chem. 2003 Nov 21;278(47):46911-8. Epub 2003 Aug 28.

49.

The coactivator p/CIP/SRC-3 facilitates retinoic acid receptor signaling via recruitment of GCN5.

Brown K, Chen Y, Underhill TM, Mymryk JS, Torchia J.

J Biol Chem. 2003 Oct 10;278(41):39402-12. Epub 2003 Jul 28.

50.

Effect of the distribution and clustering of the type I A BMP receptor (ALK3) with the type II BMP receptor on the activation of signalling pathways.

Nohe A, Keating E, Underhill TM, Knaus P, Petersen NO.

J Cell Sci. 2003 Aug 15;116(Pt 16):3277-84. Epub 2003 Jun 26.

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