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Items: 23


Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates.

Unciuleac MC, Goldgur Y, Shuman S.

J Biol Chem. 2019 Mar 29;294(13):5094-5104. doi: 10.1074/jbc.RA119.007445. Epub 2019 Feb 4.


Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD+-dependent polynucleotide ligases.

Unciuleac MC, Goldgur Y, Shuman S.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2592-2597. doi: 10.1073/pnas.1619220114. Epub 2017 Feb 21.


Homologous recombination mediated by the mycobacterial AdnAB helicase without end resection by the AdnAB nucleases.

Gupta R, Unciuleac MC, Shuman S, Glickman MS.

Nucleic Acids Res. 2017 Jan 25;45(2):762-774. doi: 10.1093/nar/gkw1130. Epub 2016 Nov 29.


Crystal Structure and Biochemical Characterization of a Mycobacterium smegmatis AAA-Type Nucleoside Triphosphatase Phosphohydrolase (Msm0858).

Unciuleac MC, Smith PC, Shuman S.

J Bacteriol. 2016 Apr 28;198(10):1521-33. doi: 10.1128/JB.00905-15. Print 2016 May 15.


Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase.

Unciuleac MC, Goldgur Y, Shuman S.

Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13868-73. doi: 10.1073/pnas.1516536112. Epub 2015 Oct 28.


Characterization of a novel eukaryal nick-sealing RNA ligase from Naegleria gruberi.

Unciuleac MC, Shuman S.

RNA. 2015 May;21(5):824-32. doi: 10.1261/rna.049197.114. Epub 2015 Mar 4.


Discrimination of RNA from DNA by polynucleotide phosphorylase.

Unciuleac MC, Shuman S.

Biochemistry. 2013 Sep 24;52(38):6702-11. doi: 10.1021/bi401041v. Epub 2013 Sep 11.


A dual role for mycobacterial RecO in RecA-dependent homologous recombination and RecA-independent single-strand annealing.

Gupta R, Ryzhikov M, Koroleva O, Unciuleac M, Shuman S, Korolev S, Glickman MS.

Nucleic Acids Res. 2013 Feb 1;41(4):2284-95. doi: 10.1093/nar/gks1298. Epub 2013 Jan 7.


Mycobacterium smegmatis RqlH defines a novel clade of bacterial RecQ-like DNA helicases with ATP-dependent 3'-5' translocase and duplex unwinding activities.

Ordonez H, Unciuleac M, Shuman S.

Nucleic Acids Res. 2012 May;40(10):4604-14. doi: 10.1093/nar/gks046. Epub 2012 Jan 28.


Double strand break unwinding and resection by the mycobacterial helicase-nuclease AdnAB in the presence of single strand DNA-binding protein (SSB).

Unciuleac MC, Shuman S.

J Biol Chem. 2010 Nov 5;285(45):34319-29. doi: 10.1074/jbc.M110.162925. Epub 2010 Aug 23.


Characterization of the mycobacterial AdnAB DNA motor provides insights into the evolution of bacterial motor-nuclease machines.

Unciuleac MC, Shuman S.

J Biol Chem. 2010 Jan 22;285(4):2632-41. doi: 10.1074/jbc.M109.076133. Epub 2009 Nov 17.


AdnAB: a new DSB-resecting motor-nuclease from mycobacteria.

Sinha KM, Unciuleac MC, Glickman MS, Shuman S.

Genes Dev. 2009 Jun 15;23(12):1423-37. doi: 10.1101/gad.1805709. Epub 2009 May 26.


Domain requirements for DNA unwinding by mycobacterial UvrD2, an essential DNA helicase.

Sinha KM, Stephanou NC, Unciuleac MC, Glickman MS, Shuman S.

Biochemistry. 2008 Sep 9;47(36):9355-64. doi: 10.1021/bi800725q. Epub 2008 Aug 15.


In vivo iron-sulfur cluster formation.

Raulfs EC, O'Carroll IP, Dos Santos PC, Unciuleac MC, Dean DR.

Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8591-6. doi: 10.1073/pnas.0803173105. Epub 2008 Jun 17.


Inhibitors of the molybdenum cofactor containing 4-hydroxybenzoyl-CoA reductase.

Johannes J, Unciuleac MC, Friedrich T, Warkentin E, Ermler U, Boll M.

Biochemistry. 2008 Apr 29;47(17):4964-72. doi: 10.1021/bi800137v. Epub 2008 Apr 5.


In vitro activation of apo-aconitase using a [4Fe-4S] cluster-loaded form of the IscU [Fe-S] cluster scaffolding protein.

Unciuleac MC, Chandramouli K, Naik S, Mayer S, Huynh BH, Johnson MK, Dean DR.

Biochemistry. 2007 Jun 12;46(23):6812-21. Epub 2007 May 17.


Formation and properties of [4Fe-4S] clusters on the IscU scaffold protein.

Chandramouli K, Unciuleac MC, Naik S, Dean DR, Huynh BH, Johnson MK.

Biochemistry. 2007 Jun 12;46(23):6804-11. Epub 2007 May 17.


Controlled expression and functional analysis of iron-sulfur cluster biosynthetic components within Azotobacter vinelandii.

Johnson DC, Unciuleac MC, Dean DR.

J Bacteriol. 2006 Nov;188(21):7551-61. Epub 2006 Aug 25.


Crystallization of 4-hydroxybenzoyl-CoA reductase and the structure of its electron donor ferredoxin.

Unciuleac M, Boll M, Warkentin E, Ermler U.

Acta Crystallogr D Biol Crystallogr. 2004 Feb;60(Pt 2):388-91. Epub 2004 Jan 23.


Mechanism of ATP-driven electron transfer catalyzed by the benzene ring-reducing enzyme benzoyl-CoA reductase.

Unciuleac M, Boll M.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13619-24. Epub 2001 Nov 6.

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