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Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome-results from a 6-month, double-blind, randomized controlled trial.

Curtis PJ, van der Velpen V, Berends L, Jennings A, Feelisch M, Umpleby AM, Evans M, Fernandez BO, Meiss MS, Minnion M, Potter J, Minihane AM, Kay CD, Rimm EB, Cassidy A.

Am J Clin Nutr. 2019 Jun 1;109(6):1535-1545. doi: 10.1093/ajcn/nqy380.


Ethnic differences in intrahepatic lipid and its association with hepatic insulin sensitivity and insulin clearance between men of black and white ethnicity with early type 2 diabetes.

Hakim O, Bello O, Bonadonna RC, Mohandas C, Shojaee-Moradie F, Jackson N, Boselli L, Whitcher B, Shuaib H, Alberti KGMM, Peacock JL, Umpleby AM, Charles-Edwards G, Amiel SA, Goff LM.

Diabetes Obes Metab. 2019 May 10. doi: 10.1111/dom.13771. [Epub ahead of print]


Black African men with early type 2 diabetes have similar muscle, liver and adipose tissue insulin sensitivity to white European men despite lower visceral fat.

Bello O, Mohandas C, Shojee-Moradie F, Jackson N, Hakim O, Alberti KGMM, Peacock JL, Umpleby AM, Amiel SA, Goff LM.

Diabetologia. 2019 May;62(5):835-844. doi: 10.1007/s00125-019-4820-6. Epub 2019 Feb 6.


Associations Between Pancreatic Lipids and β-Cell Function in Black African and White European Men With Type 2 Diabetes.

Hakim O, Bonadonna RC, Mohandas C, Billoo Z, Sunderland A, Boselli L, Alberti KGMM, Peacock JL, Umpleby AM, Charles-Edwards G, Amiel SA, Goff LM.

J Clin Endocrinol Metab. 2019 Apr 1;104(4):1201-1210. doi: 10.1210/jc.2018-01809.


Lixisenatide Reduces Chylomicron Triacylglycerol by Increased Clearance.

Whyte MB, Shojaee-Moradie F, Sharaf SE, Jackson NC, Fielding B, Hovorka R, Mendis J, Russell-Jones D, Umpleby AM.

J Clin Endocrinol Metab. 2019 Feb 1;104(2):359-368. doi: 10.1210/jc.2018-01176.


Ethnic differences in insulin secretory function between black African and white European men with early type 2 diabetes.

Mohandas C, Bonadonna R, Shojee-Moradie F, Jackson N, Boselli L, Alberti KGMM, Peacock JL, Umpleby AM, Amiel SA, Goff LM.

Diabetes Obes Metab. 2018 Jul;20(7):1678-1687. doi: 10.1111/dom.13283. Epub 2018 Apr 14.


Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets.

Umpleby AM, Shojaee-Moradie F, Fielding B, Li X, Marino A, Alsini N, Isherwood C, Jackson N, Ahmad A, Stolinski M, Lovegrove JA, Johnsen S, Jeewaka R Mendis AS, Wright J, Wilinska ME, Hovorka R, Bell JD, Thomas EL, Frost GS, Griffin BA.

Clin Sci (Lond). 2017 Oct 17;131(21):2561-2573. doi: 10.1042/CS20171208. Print 2017 Nov 1.


Rifaximin in non-alcoholic steatohepatitis: An open-label pilot study.

Cobbold JFL, Atkinson S, Marchesi JR, Smith A, Wai SN, Stove J, Shojaee-Moradie F, Jackson N, Umpleby AM, Fitzpatrick J, Thomas EL, Bell JD, Holmes E, Taylor-Robinson SD, Goldin RD, Yee MS, Anstee QM, Thursz MR.

Hepatol Res. 2018 Jan;48(1):69-77. doi: 10.1111/hepr.12904. Epub 2017 May 31.


Measurement of hepatic insulin sensitivity early after the bypass of the proximal small bowel in humans.

Miras AD, Herring R, Vusirikala A, Shojaee-Moradi F, Jackson NC, Chandaria S, Jackson SN, Goldstone AP, Hakim N, Patel AG, Umpleby AM, Le Roux CW.

Obes Sci Pract. 2017 Mar;3(1):95-98. doi: 10.1002/osp4.76. Epub 2016 Dec 29.


Role of the Enterocyte in Fructose-Induced Hypertriglyceridaemia.

Steenson S, Umpleby AM, Lovegrove JA, Jackson KG, Fielding BA.

Nutrients. 2017 Apr 1;9(4). pii: E349. doi: 10.3390/nu9040349. Review.


Exercise Training Reduces Liver Fat and Increases Rates of VLDL Clearance But Not VLDL Production in NAFLD.

Shojaee-Moradie F, Cuthbertson DJ, Barrett M, Jackson NC, Herring R, Thomas EL, Bell J, Kemp GJ, Wright J, Umpleby AM.

J Clin Endocrinol Metab. 2016 Nov;101(11):4219-4228. Epub 2016 Sep 1.


Exercise-induced improvements in liver fat and endothelial function are not sustained 12 months following cessation of exercise supervision in nonalcoholic fatty liver disease.

Pugh CJ, Sprung VS, Jones H, Richardson P, Shojaee-Moradie F, Umpleby AM, Green DJ, Cable NT, Trenell MI, Kemp GJ, Cuthbertson DJ.

Int J Obes (Lond). 2016 Dec;40(12):1927-1930. doi: 10.1038/ijo.2016.123. Epub 2016 Jul 21.


Dissociation between exercise-induced reduction in liver fat and changes in hepatic and peripheral glucose homoeostasis in obese patients with non-alcoholic fatty liver disease.

Cuthbertson DJ, Shojaee-Moradie F, Sprung VS, Jones H, Pugh CJ, Richardson P, Kemp GJ, Barrett M, Jackson NC, Thomas EL, Bell JD, Umpleby AM.

Clin Sci (Lond). 2016 Jan;130(2):93-104. doi: 10.1042/CS20150447. Epub 2015 Sep 30.


Effect of subcutaneous insulin detemir on glucose flux, lipolysis and electroencephalography in type 1 diabetes.

Herring R, Knight R, Shojaee-Moradie F, Johnsen S, Umpleby AM, Jackson N, Jones R, Dijk DJ, Russell-Jones DL.

Diabetes Obes Metab. 2015 Nov;17(11):1100-3. doi: 10.1111/dom.12553. Epub 2015 Sep 29.


Safety, efficacy and glucose turnover of reduced prandial boluses during closed-loop therapy in adolescents with type 1 diabetes: a randomized clinical trial.

Elleri D, Biagioni M, Allen JM, Kumareswaran K, Leelarathna L, Caldwell K, Nodale M, Wilinska ME, Haidar A, Calhoun P, Kollman C, Jackson NC, Umpleby AM, Acerini CL, Dunger DB, Hovorka R.

Diabetes Obes Metab. 2015 Dec;17(12):1173-9. doi: 10.1111/dom.12549. Epub 2015 Oct 9.


HORMONE MEASUREMENT GUIDELINES: Tracing lipid metabolism: the value of stable isotopes.

Umpleby AM.

J Endocrinol. 2015 Sep;226(3):G1-10. doi: 10.1530/JOE-14-0610. Epub 2015 Jun 5. Review.


Formoterol, a highly β2-selective agonist, induces gender-dimorphic whole body leucine metabolism in humans.

Lee P, Birzniece V, Umpleby AM, Poljak A, Ho KK.

Metabolism. 2015 Apr;64(4):506-12. doi: 10.1016/j.metabol.2014.12.005. Epub 2014 Dec 26.


Effect of subcutaneous insulin detemir on glucose flux and lipolysis during hyperglycaemia in people with type 1 diabetes.

Herring RA, Shojaee-Moradie F, Umpleby AM, Jones R, Jackson N, Russell-Jones DL.

Diabetes Obes Metab. 2015 May;17(5):459-67. doi: 10.1111/dom.12434. Epub 2015 Feb 1.


Exercise training reverses endothelial dysfunction in nonalcoholic fatty liver disease.

Pugh CJ, Spring VS, Kemp GJ, Richardson P, Shojaee-Moradie F, Umpleby AM, Green DJ, Cable NT, Jones H, Cuthbertson DJ.

Am J Physiol Heart Circ Physiol. 2014 Nov 1;307(9):H1298-306.


Ectopic lipid storage in non-alcoholic fatty liver disease is not mediated by impaired mitochondrial oxidative capacity in skeletal muscle.

Cuthbertson DJ, Irwin A, Sprung VS, Jones H, Pugh CJ, Daousi C, Adams VL, Bimson WE, Shojaee-Moradie F, Richardson P, Umpleby AM, Wilding JP, Kemp GJ.

Clin Sci (Lond). 2014 Dec;127(12):655-63. doi: 10.1042/CS20130404.


Efficacy of increased resistant starch consumption in human type 2 diabetes.

Bodinham CL, Smith L, Thomas EL, Bell JD, Swann JR, Costabile A, Russell-Jones D, Umpleby AM, Robertson MD.

Endocr Connect. 2014 Apr 15;3(2):75-84. doi: 10.1530/EC-14-0036. Print 2014.


Glucose turnover after replacement of usual therapy by insulin in insulin-naive type 2 diabetes subjects.

Thabit H, Kumareswaran K, Haidar A, Leelarathna L, Caldwell K, Elleri D, Allen JM, Nodale M, Wilinska ME, Jackson NC, Umpleby AM, Evans ML, Hovorka R.

J Clin Endocrinol Metab. 2014 Jun;99(6):2225-32. doi: 10.1210/jc.2013-4519. Epub 2014 Feb 25.


Short-term administration of pegvisomant improves hepatic insulin sensitivity and reduces soleus muscle intramyocellular lipid content in young adults with type 1 diabetes.

Thankamony A, Tossavainen PH, Sleigh A, Acerini C, Elleri D, Dalton RN, Jackson NC, Umpleby AM, Williams RM, Dunger DB.

J Clin Endocrinol Metab. 2014 Feb;99(2):639-47. doi: 10.1210/jc.2013-3264. Epub 2013 Dec 11.


Prandial hypertriglyceridemia in metabolic syndrome is due to an overproduction of both chylomicron and VLDL triacylglycerol.

Shojaee-Moradie F, Ma Y, Lou S, Hovorka R, Umpleby AM.

Diabetes. 2013 Dec;62(12):4063-9. doi: 10.2337/db13-0935. Epub 2013 Aug 29. Erratum in: Diabetes. 2014 Feb;63(2):815.


Exercise training improves cutaneous microvascular function in nonalcoholic fatty liver disease.

Pugh CJ, Cuthbertson DJ, Sprung VS, Kemp GJ, Richardson P, Umpleby AM, Green DJ, Cable NT, Jones H.

Am J Physiol Endocrinol Metab. 2013 Jul 1;305(1):E50-8. doi: 10.1152/ajpendo.00055.2013. Epub 2013 May 7.


A novel method for measuring intestinal and hepatic triacylglycerol kinetics.

Sun F, Stolinski M, Shojaee-Moradie F, Lou S, Ma Y, Hovorka R, Umpleby AM.

Am J Physiol Endocrinol Metab. 2013 Oct 15;305(8):E1041-7. doi: 10.1152/ajpendo.00105.2013. Epub 2013 Apr 16.


Absorption patterns of meals containing complex carbohydrates in type 1 diabetes.

Elleri D, Allen JM, Harris J, Kumareswaran K, Nodale M, Leelarathna L, Acerini CL, Haidar A, Wilinska ME, Jackson N, Umpleby AM, Evans ML, Dunger DB, Hovorka R.

Diabetologia. 2013 May;56(5):1108-17. doi: 10.1007/s00125-013-2852-x. Epub 2013 Feb 23.


Effects of three weeks of mild sleep restriction implemented in the home environment on multiple metabolic and endocrine markers in healthy young men.

Robertson MD, Russell-Jones D, Umpleby AM, Dijk DJ.

Metabolism. 2013 Feb;62(2):204-11. doi: 10.1016/j.metabol.2012.07.016. Epub 2012 Sep 15.


Development of a method to measure preβHDL and αHDL apoA-I enrichment for stable isotopic studies of HDL kinetics.

Li X, Stolinski M, Umpleby AM.

Lipids. 2012 Oct;47(10):1011-8. Epub 2012 Aug 11.


Insulin-sensitizing effects on muscle and adipose tissue after dietary fiber intake in men and women with metabolic syndrome.

Robertson MD, Wright JW, Loizon E, Debard C, Vidal H, Shojaee-Moradie F, Russell-Jones D, Umpleby AM.

J Clin Endocrinol Metab. 2012 Sep;97(9):3326-32. doi: 10.1210/jc.2012-1513. Epub 2012 Jun 28.


Gender differences in VLDL1 and VLDL2 triglyceride kinetics and fatty acid kinetics in obese postmenopausal women and obese men.

Sarac I, Backhouse K, Shojaee-Moradie F, Stolinski M, Robertson MD, Bell JD, Thomas EL, Hovorka R, Wright J, Umpleby AM.

J Clin Endocrinol Metab. 2012 Jul;97(7):2475-81. doi: 10.1210/jc.2011-3248. Epub 2012 Apr 16.


Validity of triple- and dual-tracer techniques to estimate glucose appearance.

Haidar A, Elleri D, Allen JM, Harris J, Kumareswaran K, Nodale M, Acerini CL, Wilinska ME, Jackson N, Umpleby AM, Evans ML, Dunger DB, Hovorka R.

Am J Physiol Endocrinol Metab. 2012 Jun 15;302(12):E1493-501. doi: 10.1152/ajpendo.00581.2011. Epub 2012 Mar 27.


Fatty acid flux and oxidation are increased by rimonabant in obese women.

Backhouse K, Sarac I, Shojaee-Moradie F, Stolinski M, Robertson MD, Frost GS, Bell JD, Thomas EL, Wright J, Russell-Jones D, Umpleby AM.

Metabolism. 2012 Sep;61(9):1220-3. doi: 10.1016/j.metabol.2012.02.012. Epub 2012 Mar 24. Erratum in: Metabolism. 2014 Apr;63(4):e7.


Hormone replacement therapy and physical function in healthy older men. Time to talk hormones?

Giannoulis MG, Martin FC, Nair KS, Umpleby AM, Sonksen P.

Endocr Rev. 2012 Jun;33(3):314-77. doi: 10.1210/er.2012-1002. Epub 2012 Mar 20. Review.


Estimating postprandial glucose fluxes using hierarchical Bayes modelling.

Haidar A, Potocka E, Boulet B, Umpleby AM, Hovorka R.

Comput Methods Programs Biomed. 2012 Oct;108(1):102-12. doi: 10.1016/j.cmpb.2012.01.010. Epub 2012 Feb 23.


Evidence for a shift to anaerobic metabolism in adipose tissue in efavirenz-containing regimens for HIV with different nucleoside backbones.

McGee KC, Shahmanesh M, Boothby M, Nightingale P, Gathercole LL, Tripathi G, Harte AL, Shojaee-Moradie F, Umpleby AM, Das S, Al-Daghri NM, McTernan PG, Tomlinson JW.

Antivir Ther. 2012;17(3):495-507. doi: 10.3851/IMP2017. Epub 2011 Dec 13.


Pathophysiology of postprandial hyperglycaemia in women with type 1 diabetes during pregnancy.

Murphy HR, Elleri D, Allen JM, Harris J, Simmons D, Rayman G, Temple RC, Umpleby AM, Dunger DB, Haidar A, Nodale M, Wilinska ME, Hovorka R.

Diabetologia. 2012 Feb;55(2):282-93. doi: 10.1007/s00125-011-2363-6. Epub 2011 Nov 12.


Insulin detemir reduces weight gain as a result of reduced food intake in patients with type 1 diabetes.

Zachariah S, Sheldon B, Shojaee-Moradie F, Jackson NC, Backhouse K, Johnsen S, Jones RH, Umpleby AM, Russell-Jones DL.

Diabetes Care. 2011 Jul;34(7):1487-91. doi: 10.2337/dc11-0098. Epub 2011 May 18.


Treatment with recombinant human insulin-like growth factor (rhIGF)-I/rhIGF binding protein-3 complex improves metabolic control in subjects with severe insulin resistance.

Regan FM, Williams RM, McDonald A, Umpleby AM, Acerini CL, O'Rahilly S, Hovorka R, Semple RK, Dunger DB.

J Clin Endocrinol Metab. 2010 May;95(5):2113-22. doi: 10.1210/jc.2009-2088. Epub 2010 Mar 16.


Adipocyte differentiation, mitochondrial gene expression and fat distribution: differences between zidovudine and tenofovir after 6 months.

Boothby M, McGee KC, Tomlinson JW, Gathercole LL, McTernan PG, Shojaee-Moradie F, Umpleby AM, Nightingale P, Shahmanesh M.

Antivir Ther. 2009;14(8):1089-100. doi: 10.3851/IMP1457.


Metabolic effects of intensive insulin therapy in critically ill patients.

Whyte MB, Jackson NC, Shojaee-Moradie F, Treacher DF, Beale RJ, Jones RH, Umpleby AM.

Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E697-705. doi: 10.1152/ajpendo.00407.2009. Epub 2009 Dec 22.


Differential effects of insulin detemir and neutral protamine Hagedorn (NPH) insulin on hepatic glucose production and peripheral glucose uptake during hypoglycaemia in type 1 diabetes.

Smeeton F, Shojaee Moradie F, Jones RH, Westergaard L, Haahr H, Umpleby AM, Russell-Jones DL.

Diabetologia. 2009 Nov;52(11):2317-23. doi: 10.1007/s00125-009-1487-4. Epub 2009 Aug 26.


Effects of rosiglitazone and pioglitazone on lipoprotein metabolism in patients with Type 2 diabetes and normal lipids.

Brackenridge AL, Jackson N, Jefferson W, Stolinski M, Shojaee-Moradie F, Hovorka R, Umpleby AM, Russell-Jones D.

Diabet Med. 2009 May;26(5):532-9. doi: 10.1111/j.1464-5491.2009.02729.x.


Pegvisomant improves insulin sensitivity and reduces overnight free fatty acid concentrations in patients with acromegaly.

Higham CE, Rowles S, Russell-Jones D, Umpleby AM, Trainer PJ.

J Clin Endocrinol Metab. 2009 Jul;94(7):2459-63. doi: 10.1210/jc.2008-2086. Epub 2009 Apr 14.


Effect of 6-month supervised exercise on low-density lipoprotein apolipoprotein B kinetics in patients with type 2 diabetes mellitus.

Stolinski M, Alam S, Jackson NC, Shojaee-Moradie F, Pentecost C, Jefferson W, Christ ER, Jones RH, Umpleby AM.

Metabolism. 2008 Nov;57(11):1608-14. doi: 10.1016/j.metabol.2008.06.018.


Severe intrauterine growth retardation and atypical diabetes associated with a translocation breakpoint disrupting regulation of the insulin-like growth factor 2 gene.

Murphy R, Baptista J, Holly J, Umpleby AM, Ellard S, Harries LW, Crolla J, Cundy T, Hattersley AT.

J Clin Endocrinol Metab. 2008 Nov;93(11):4373-80. doi: 10.1210/jc.2008-0819. Epub 2008 Aug 26.


The effects of growth hormone and/or testosterone on whole body protein kinetics and skeletal muscle gene expression in healthy elderly men: a randomized controlled trial.

Giannoulis MG, Jackson N, Shojaee-Moradie F, Nair KS, Sonksen PH, Martin FC, Umpleby AM.

J Clin Endocrinol Metab. 2008 Aug;93(8):3066-74. doi: 10.1210/jc.2007-2695. Epub 2008 May 13.


Impact of growth hormone and dehydroepiandrosterone on protein metabolism in glucocorticoid-treated patients.

Burt MG, Johannsson G, Umpleby AM, Chisholm DJ, Ho KK.

J Clin Endocrinol Metab. 2008 Mar;93(3):688-95. doi: 10.1210/jc.2007-2333. Epub 2008 Jan 8.


Relationship between GH-induced metabolic changes and changes in body composition: a dose and time course study in GH-deficient adults.

Burt MG, Gibney J, Hoffman DM, Umpleby AM, Ho KK.

Growth Horm IGF Res. 2008 Feb;18(1):55-64. Epub 2007 Aug 21.


Impact of acute and chronic low-dose glucocorticoids on protein metabolism.

Burt MG, Johannsson G, Umpleby AM, Chisholm DJ, Ho KK.

J Clin Endocrinol Metab. 2007 Oct;92(10):3923-9. Epub 2007 Jul 24.


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