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Items: 1 to 50 of 244

1.

Author Correction: Microbiota therapy acts via a regulatory T cell MyD88/RORγt pathway to suppress food allergy.

Abdel-Gadir A, Stephen-Victor E, Gerber GK, Noval Rivas M, Wang S, Harb H, Wang L, Li N, Crestani E, Spielman S, Secor W, Biehl H, DiBenedetto N, Dong X, Umetsu DT, Bry L, Rachid R, Chatila TA.

Nat Med. 2019 Sep;25(9):1458. doi: 10.1038/s41591-019-0572-6.

PMID:
31420602
2.

Microbiota therapy acts via a regulatory T cell MyD88/RORγt pathway to suppress food allergy.

Abdel-Gadir A, Stephen-Victor E, Gerber GK, Noval Rivas M, Wang S, Harb H, Wang L, Li N, Crestani E, Spielman S, Secor W, Biehl H, DiBenedetto N, Dong X, Umetsu DT, Bry L, Rachid R, Chatila TA.

Nat Med. 2019 Jul;25(7):1164-1174. doi: 10.1038/s41591-019-0461-z. Epub 2019 Jun 24. Erratum in: Nat Med. 2019 Sep;25(9):1458.

PMID:
31235962
3.

Pregnancy outcomes in the omalizumab pregnancy registry and a disease-matched comparator cohort.

Namazy JA, Blais L, Andrews EB, Scheuerle AE, Cabana MD, Thorp JM, Umetsu DT, Veith JH, Sun D, Kaufman DG, Covington DL, Mukhopadhyay S, Fogel RB, Lopez-Leon S, Spain CV.

J Allergy Clin Immunol. 2019 May 27. pii: S0091-6749(19)30690-6. doi: 10.1016/j.jaci.2019.05.019. [Epub ahead of print]

4.

Blockade of RGMb inhibits allergen-induced airways disease.

Yu S, Leung KM, Kim HY, Umetsu SE, Xiao Y, Albacker LA, Lee HJ, Umetsu DT, Freeman GJ, DeKruyff RH.

J Allergy Clin Immunol. 2019 Jul;144(1):94-108.e11. doi: 10.1016/j.jaci.2018.12.1022. Epub 2019 Jan 29.

5.

Immunoglobulin E blockade during food allergen ingestion enhances the induction of inhibitory immunoglobulin G antibodies.

Stranks AJ, Minnicozzi SC, Miller SJ, Burton OT, Logsdon SL, Spergel JM, Nadeau KC, Pongracic JA, Umetsu DT, Rachid R, MacGinnitie AJ, Schneider LC, Oettgen HC.

Ann Allergy Asthma Immunol. 2019 Feb;122(2):213-215. doi: 10.1016/j.anai.2018.10.024. Epub 2018 Nov 4. No abstract available.

PMID:
30404033
6.

Long-Term Outcome of Peanut Oral Immunotherapy Facilitated Initially by Omalizumab.

Yee CSK, Albuhairi S, Noh E, El-Khoury K, Rezaei S, Abdel-Gadir A, Umetsu DT, Burke-Roberts E, LeBovidge J, Schneider L, Rachid R.

J Allergy Clin Immunol Pract. 2019 Feb;7(2):451-461.e7. doi: 10.1016/j.jaip.2018.09.015. Epub 2018 Sep 26.

PMID:
30267889
7.

Competition for Space Is Controlled by Apoptosis-Induced Change of Local Epithelial Topology.

Tsuboi A, Ohsawa S, Umetsu D, Sando Y, Kuranaga E, Igaki T, Fujimoto K.

Curr Biol. 2018 Jul 9;28(13):2115-2128.e5. doi: 10.1016/j.cub.2018.05.029. Epub 2018 Jun 18.

8.

A natural killer T-cell subset that protects against airway hyperreactivity.

Chuang YT, Leung K, Chang YJ, DeKruyff RH, Savage PB, Cruse R, Benoit C, Elewaut D, Baumgarth N, Umetsu DT.

J Allergy Clin Immunol. 2019 Feb;143(2):565-576.e7. doi: 10.1016/j.jaci.2018.03.022. Epub 2018 May 29.

PMID:
29852257
9.

Oral immunotherapy with omalizumab reverses the Th2 cell-like programme of regulatory T cells and restores their function.

Abdel-Gadir A, Schneider L, Casini A, Charbonnier LM, Little SV, Harrington T, Umetsu DT, Rachid R, Chatila TA.

Clin Exp Allergy. 2018 Jul;48(7):825-836. doi: 10.1111/cea.13161. Epub 2018 May 29.

10.

Inference of Cell Mechanics in Heterogeneous Epithelial Tissue Based on Multivariate Clone Shape Quantification.

Tsuboi A, Umetsu D, Kuranaga E, Fujimoto K.

Front Cell Dev Biol. 2017 Aug 3;5:68. doi: 10.3389/fcell.2017.00068. eCollection 2017.

11.

Anaphylaxis associated with omalizumab administration: Risk factors and patient characteristics.

Lieberman PL, Jones I, Rajwanshi R, Rosén K, Umetsu DT.

J Allergy Clin Immunol. 2017 Dec;140(6):1734-1736.e4. doi: 10.1016/j.jaci.2017.07.013. Epub 2017 Aug 7. No abstract available.

12.

Planar polarized contractile actomyosin networks in dynamic tissue morphogenesis.

Umetsu D, Kuranaga E.

Curr Opin Genet Dev. 2017 Aug;45:90-96. doi: 10.1016/j.gde.2017.03.012. Epub 2017 Apr 15. Review.

PMID:
28419933
13.

Reply.

Lieberman PL, Umetsu DT, Carrigan GJ, Rahmaoui A.

J Allergy Clin Immunol. 2017 May;139(5):1718-1719. doi: 10.1016/j.jaci.2016.12.976. Epub 2017 Mar 3. No abstract available.

PMID:
28268016
14.

Omalizumab facilitates rapid oral desensitization for peanut allergy.

MacGinnitie AJ, Rachid R, Gragg H, Little SV, Lakin P, Cianferoni A, Heimall J, Makhija M, Robison R, Chinthrajah RS, Lee J, Lebovidge J, Dominguez T, Rooney C, Lewis MO, Koss J, Burke-Roberts E, Chin K, Logvinenko T, Pongracic JA, Umetsu DT, Spergel J, Nadeau KC, Schneider LC.

J Allergy Clin Immunol. 2017 Mar;139(3):873-881.e8. doi: 10.1016/j.jaci.2016.08.010. Epub 2016 Sep 5.

15.

Segmentation and Quantitative Analysis of Epithelial Tissues.

Aigouy B, Umetsu D, Eaton S.

Methods Mol Biol. 2016;1478:227-239. Review.

PMID:
27730585
16.

Mechanisms by which obesity impacts upon asthma.

Umetsu DT.

Thorax. 2017 Feb;72(2):174-177. doi: 10.1136/thoraxjnl-2016-209130. Epub 2016 Sep 26. Review.

PMID:
27672120
17.

IL-33 Drives Augmented Responses to Ozone in Obese Mice.

Mathews JA, Krishnamoorthy N, Kasahara DI, Cho Y, Wurmbrand AP, Ribeiro L, Smith D, Umetsu D, Levy BD, Shore SA.

Environ Health Perspect. 2017 Feb;125(2):246-253. doi: 10.1289/EHP272. Epub 2016 Jul 29.

18.

Anaphylactic reactions associated with omalizumab administration: Analysis of a case-control study.

Lieberman PL, Umetsu DT, Carrigan GJ, Rahmaoui A.

J Allergy Clin Immunol. 2016 Sep;138(3):913-915.e2. doi: 10.1016/j.jaci.2016.03.030. Epub 2016 Apr 26. No abstract available.

19.

Innate lymphoid cells in asthma: Will they take your breath away?

Kim HY, Umetsu DT, Dekruyff RH.

Eur J Immunol. 2016 Apr;46(4):795-806. doi: 10.1002/eji.201444557. Epub 2016 Mar 16. Review.

20.

A local difference in Hedgehog signal transduction increases mechanical cell bond tension and biases cell intercalations along the Drosophila anteroposterior compartment boundary.

Rudolf K, Umetsu D, Aliee M, Sui L, Jülicher F, Dahmann C.

Development. 2015 Nov 15;142(22):3845-58. doi: 10.1242/dev.125542.

21.

Oral immunotherapy and anti-IgE antibody treatment for food allergy.

Umetsu DT, Rachid R, Schneider LC.

World Allergy Organ J. 2015 Jul 6;8(1):20. doi: 10.1186/s40413-015-0070-3. eCollection 2015.

22.

Signals and mechanics shaping compartment boundaries in Drosophila.

Umetsu D, Dahmann C.

Wiley Interdiscip Rev Dev Biol. 2015 Jul-Aug;4(4):407-17. doi: 10.1002/wdev.178. Epub 2015 Mar 9.

PMID:
25755098
23.

An RNA interference screen for genes required to shape the anteroposterior compartment boundary in Drosophila identifies the Eph receptor.

Umetsu D, Dunst S, Dahmann C.

PLoS One. 2014 Dec 4;9(12):e114340. doi: 10.1371/journal.pone.0114340. eCollection 2014.

24.

A new player on the psoriasis block: IL-17A- and IL-22-producing innate lymphoid cells.

Ward NL, Umetsu DT.

J Invest Dermatol. 2014 Sep;134(9):2305-2307. doi: 10.1038/jid.2014.216.

25.

Targeting IgE to facilitate oral immunotherapy for food allergy: a potential new role for anti-IgE therapy?

Umetsu DT.

Expert Rev Clin Immunol. 2014 Sep;10(9):1125-8. doi: 10.1586/1744666X.2014.948849.

PMID:
25119422
26.

Local increases in mechanical tension shape compartment boundaries by biasing cell intercalations.

Umetsu D, Aigouy B, Aliee M, Sui L, Eaton S, Jülicher F, Dahmann C.

Curr Biol. 2014 Aug 4;24(15):1798-805. doi: 10.1016/j.cub.2014.06.052. Epub 2014 Jul 24.

27.

Oral immunotherapy induces IgG antibodies that act through FcγRIIb to suppress IgE-mediated hypersensitivity.

Burton OT, Logsdon SL, Zhou JS, Medina-Tamayo J, Abdel-Gadir A, Noval Rivas M, Koleoglou KJ, Chatila TA, Schneider LC, Rachid R, Umetsu DT, Oettgen HC.

J Allergy Clin Immunol. 2014 Dec;134(6):1310-1317.e6. doi: 10.1016/j.jaci.2014.05.042. Epub 2014 Jul 16.

28.

Innate immunity in the lung regulates the development of asthma.

DeKruyff RH, Yu S, Kim HY, Umetsu DT.

Immunol Rev. 2014 Jul;260(1):235-48. doi: 10.1111/imr.12187. Review.

PMID:
24942693
29.

RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance.

Xiao Y, Yu S, Zhu B, Bedoret D, Bu X, Francisco LM, Hua P, Duke-Cohan JS, Umetsu DT, Sharpe AH, DeKruyff RH, Freeman GJ.

J Exp Med. 2014 May 5;211(5):943-59. doi: 10.1084/jem.20130790. Epub 2014 Apr 21.

30.

Innate lymphoid cells and asthma.

Yu S, Kim HY, Chang YJ, DeKruyff RH, Umetsu DT.

J Allergy Clin Immunol. 2014 Apr;133(4):943-50; quiz 51. doi: 10.1016/j.jaci.2014.02.015. Review.

PMID:
24679467
31.

Consequences of antibiotics and infections in infancy: bugs, drugs, and wheezing.

Ong MS, Umetsu DT, Mandl KD.

Ann Allergy Asthma Immunol. 2014 May;112(5):441-445.e1. doi: 10.1016/j.anai.2014.01.022. Epub 2014 Mar 13.

PMID:
24631182
32.

Enhanced shedding of extracellular vesicles from amoeboid prostate cancer cells: potential effects on the tumor microenvironment.

Kim J, Morley S, Le M, Bedoret D, Umetsu DT, Di Vizio D, Freeman MR.

Cancer Biol Ther. 2014 Apr;15(4):409-18. doi: 10.4161/cbt.27627. Epub 2014 Jan 14.

33.

Budesonide nebulization added to systemic prednisolone in the treatment of acute asthma in children: a double-blind, randomized, controlled trial.

Alangari AA, Malhis N, Mubasher M, Al-Ghamedi N, Al-Tannir M, Riaz M, Umetsu DT, Al-Tamimi S.

Chest. 2014 Apr;145(4):772-778. doi: 10.1378/chest.13-2298.

34.

Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice.

Kasahara DI, Kim HY, Mathews JA, Verbout NG, Williams AS, Wurmbrand AP, Ninin FM, Neto FL, Benedito LA, Hug C, Umetsu DT, Shore SA.

Am J Physiol Lung Cell Mol Physiol. 2014 Mar 15;306(6):L508-20. doi: 10.1152/ajplung.00235.2013. Epub 2013 Dec 31.

35.

Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.

Kim HY, Lee HJ, Chang YJ, Pichavant M, Shore SA, Fitzgerald KA, Iwakura Y, Israel E, Bolger K, Faul J, DeKruyff RH, Umetsu DT.

Nat Med. 2014 Jan;20(1):54-61. doi: 10.1038/nm.3423. Epub 2013 Dec 15.

36.

A pilot study of omalizumab to facilitate rapid oral desensitization in high-risk peanut-allergic patients.

Schneider LC, Rachid R, LeBovidge J, Blood E, Mittal M, Umetsu DT.

J Allergy Clin Immunol. 2013 Dec;132(6):1368-74. doi: 10.1016/j.jaci.2013.09.046. Epub 2013 Oct 28.

37.

Synthesis of fungal glycolipid asperamide B and investigation of its ability to stimulate natural killer T cells.

Chaudhary V, Albacker LA, Deng S, Chuang YT, Li Y, Umetsu DT, Savage PB.

Org Lett. 2013 Oct 18;15(20):5242-5. doi: 10.1021/ol4024375. Epub 2013 Oct 10.

PMID:
24111801
38.

Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity.

Albacker LA, Chaudhary V, Chang YJ, Kim HY, Chuang YT, Pichavant M, DeKruyff RH, Savage PB, Umetsu DT.

Nat Med. 2013 Oct;19(10):1297-304. doi: 10.1038/nm.3321. Epub 2013 Sep 1.

39.

Asthma diagnosis and treatment - 1012. The efficacy of budesonide in the treatmetn of acute asthma in children: a double-blind, randomized, controlled trial.

Alangari AA, Malhis N, Mubasher M, Al-Ghamdi N, Al-Tannir M, Riaz M, Umetsu D, Al-Tamimi S.

World Allergy Organ J. 2013 Apr 23;6 Suppl 1:P12. doi: 10.1186/1939-4551-6-S1-P12. Epub 2013 Apr 23. No abstract available.

40.

Immunologic effects of omalizumab in children with severe refractory atopic dermatitis: a randomized, placebo-controlled clinical trial.

Iyengar SR, Hoyte EG, Loza A, Bonaccorso S, Chiang D, Umetsu DT, Nadeau KC.

Int Arch Allergy Immunol. 2013;162(1):89-93. doi: 10.1159/000350486. Epub 2013 Jun 27.

41.

The role of type 2 innate lymphoid cells in asthma.

Chang YJ, DeKruyff RH, Umetsu DT.

J Leukoc Biol. 2013 Nov;94(5):933-40. doi: 10.1189/jlb.0313127. Epub 2013 Jun 25. Review.

PMID:
23801654
42.

T-cell immunoglobulin and mucin domain 1 deficiency eliminates airway hyperreactivity triggered by the recognition of airway cell death.

Kim HY, Chang YJ, Chuang YT, Lee HH, Kasahara DI, Martin T, Hsu JT, Savage PB, Shore SA, Freeman GJ, Dekruyff RH, Umetsu DT.

J Allergy Clin Immunol. 2013 Aug;132(2):414-25.e6. doi: 10.1016/j.jaci.2013.03.025. Epub 2013 May 11.

43.

TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine.

Jemielity S, Wang JJ, Chan YK, Ahmed AA, Li W, Monahan S, Bu X, Farzan M, Freeman GJ, Umetsu DT, Dekruyff RH, Choe H.

PLoS Pathog. 2013 Mar;9(3):e1003232. doi: 10.1371/journal.ppat.1003232. Epub 2013 Mar 28.

44.

Intronic SH2D1A mutation with impaired SAP expression and agammaglobulinemia.

Recher M, Fried AJ, Massaad MJ, Kim HY, Rizzini M, Frugoni F, Walter JE, Mathew D, Eibel H, Hess C, Giliani S, Umetsu DT, Notarangelo LD, Geha RS.

Clin Immunol. 2013 Feb;146(2):84-9. doi: 10.1016/j.clim.2012.11.007. Epub 2012 Dec 7.

45.

Oral immunotherapy for food allergy: towards a new horizon.

Khoriaty E, Umetsu DT.

Allergy Asthma Immunol Res. 2013 Jan;5(1):3-15. doi: 10.4168/aair.2013.5.1.3. Epub 2012 Nov 28.

46.

TIM-4, expressed by medullary macrophages, regulates respiratory tolerance by mediating phagocytosis of antigen-specific T cells.

Albacker LA, Yu S, Bedoret D, Lee WL, Umetsu SE, Monahan S, Freeman GJ, Umetsu DT, DeKruyff RH.

Mucosal Immunol. 2013 May;6(3):580-90. doi: 10.1038/mi.2012.100. Epub 2012 Nov 14.

47.

Immunological mechanisms for desensitization and tolerance in food allergy.

Rachid R, Umetsu DT.

Semin Immunopathol. 2012 Sep;34(5):689-702. doi: 10.1007/s00281-012-0333-9. Epub 2012 Jul 21. Review.

48.

Early exposure to germs and the Hygiene Hypothesis.

Umetsu DT.

Cell Res. 2012 Aug;22(8):1210-1. doi: 10.1038/cr.2012.65. Epub 2012 Apr 24.

49.

Pulmonary inflammation induced by subacute ozone is augmented in adiponectin-deficient mice: role of IL-17A.

Kasahara DI, Kim HY, Williams AS, Verbout NG, Tran J, Si H, Wurmbrand AP, Jastrab J, Hug C, Umetsu DT, Shore SA.

J Immunol. 2012 May 1;188(9):4558-67. doi: 10.4049/jimmunol.1102363. Epub 2012 Apr 2.

50.

Binding of hepatitis A virus to its cellular receptor 1 inhibits T-regulatory cell functions in humans.

Manangeeswaran M, Jacques J, Tami C, Konduru K, Amharref N, Perrella O, Casasnovas JM, Umetsu DT, Dekruyff RH, Freeman GJ, Perrella A, Kaplan GG.

Gastroenterology. 2012 Jun;142(7):1516-25.e3. doi: 10.1053/j.gastro.2012.02.039. Epub 2012 Mar 16.

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