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Items: 1 to 50 of 141

1.

Characterization of steroid 5α-reductase involved in α-tomatine biosynthesis in tomatoes.

Akiyama R, Lee HJ, Nakayasu M, Osakabe K, Osakabe Y, Umemoto N, Saito K, Muranaka T, Sugimoto Y, Mizutani M.

Plant Biotechnol (Tokyo). 2019 Dec 25;36(4):253-263. doi: 10.5511/plantbiotechnology.19.1030a.

2.

Digital zoom is a useful, simple, and cost-effective method of reducing radiation exposure in percutaneous coronary intervention.

Hasegawa K, Umemoto N, Inoue S, Iio Y, Shibata N, Mizutani T, Sawamura A, Sugiura T, Taniguchi T, Asai T, Yamada M, Ishii H, Murohara T, Shimizu K.

Cardiovasc Interv Ther. 2020 Jan 14. doi: 10.1007/s12928-020-00639-5. [Epub ahead of print]

PMID:
31939067
3.

Clinical outcomes after percutaneous coronary intervention in non-dialysis patients with acute coronary syndrome and advanced renal dysfunction.

Uemura Y, Ishikawa S, Takemoto K, Negishi Y, Tanaka A, Takagi K, Yoshioka N, Umemoto N, Inoue Y, Morishima I, Shibata N, Asano H, Ishii H, Watarai M, Murohara T; N-registry investigators.

Clin Exp Nephrol. 2020 Jan 6. doi: 10.1007/s10157-019-01839-x. [Epub ahead of print]

PMID:
31903510
4.

Identification of α-Tomatine 23-Hydroxylase Involved in the Detoxification of a Bitter Glycoalkaloid.

Nakayasu M, Akiyama R, Kobayashi M, Lee HJ, Kawasaki T, Watanabe B, Urakawa S, Kato J, Sugimoto Y, Iijima Y, Saito K, Muranaka T, Umemoto N, Mizutani M.

Plant Cell Physiol. 2020 Jan 1;61(1):21-28. doi: 10.1093/pcp/pcz224.

PMID:
31816045
5.

Influence of Preadmission Frailty on Short- and Mid-Term Prognoses in Octogenarians With ST-Elevation Myocardial Infarction.

Yoshioka N, Takagi K, Morishima I, Morita Y, Uemura Y, Inoue Y, Umemoto N, Shibata N, Negishi Y, Yoshida R, Tanaka A, Ishii H, Murohara T; N-Registry Investigators.

Circ J. 2019 Dec 25;84(1):109-118. doi: 10.1253/circj.CJ-19-0467. Epub 2019 Nov 29.

6.

Efficient genome engineering using Platinum TALEN in potato.

Yasumoto S, Umemoto N, Lee HJ, Nakayasu M, Sawai S, Sakuma T, Yamamoto T, Mizutani M, Saito K, Muranaka T.

Plant Biotechnol (Tokyo). 2019 Sep 25;36(3):167-173. doi: 10.5511/plantbiotechnology.19.0805a.

7.

Multimodality findings of coronary stenosis and aneurysm in Takayasu arteritis: a case report.

Shibata N, Taniguchi T, Umemoto N, Shimizu K, Murohara T.

Coron Artery Dis. 2019 Nov;30(7):551-552. doi: 10.1097/MCA.0000000000000749. No abstract available.

PMID:
30998608
8.

Erythrodermic linear IgA/IgG bullous dermatosis.

Matsumoto T, Nakamura S, Ishii N, Umemoto N, Kawase M, Demitsu T, Hashimoto T.

Eur J Dermatol. 2019 Apr 1;29(2):220-221. doi: 10.1684/ejd.2019.3503. No abstract available.

PMID:
30973330
9.

Correction to: The lactate clearance calculated using serum lactate level 6 h after is an important prognostic predictor after extracorporeal cardiopulmonary resuscitation: a single-center retrospective observational study.

Mizutani T, Umemoto N, Taniguchi T, Ishii H, Hiramatsu Y, Arata K, Takuya H, Inoue S, Sugiura T, Asai T, Yamada M, Murohara T, Shimizu K.

J Intensive Care. 2019 Mar 21;7:18. doi: 10.1186/s40560-019-0370-8. eCollection 2019.

10.

Identification of a 3β-Hydroxysteroid Dehydrogenase/ 3-Ketosteroid Reductase Involved in α-Tomatine Biosynthesis in Tomato.

Lee HJ, Nakayasu M, Akiyama R, Kobayashi M, Miyachi H, Sugimoto Y, Umemoto N, Saito K, Muranaka T, Mizutani M.

Plant Cell Physiol. 2019 Jun 1;60(6):1304-1315. doi: 10.1093/pcp/pcz049.

PMID:
30892648
11.

Axillary granular parakeratosis with osmidrosis successfully treated with topical maxacalcitol.

Demitsu T, Nakamura S, Takazawa M, Kakurai M, Umemoto N, Kawase M.

J Dermatol. 2019 May;46(5):e155-e157. doi: 10.1111/1346-8138.14738. Epub 2018 Dec 21. No abstract available.

PMID:
30575121
12.

Contrast-Induced Nephropathy and Long-Term Clinical Outcomes Following Percutaneous Coronary Intervention in Patients With Advanced Renal Dysfunction (Estimated Glomerular Filtration Rate <30 ml/min/1.73 m2).

Negishi Y, Tanaka A, Ishii H, Takagi K, Inoue Y, Uemura Y, Umemoto N, Yoshioka N, Morishima I, Asano H, Watarai M, Shibata N, Suzuki S, Murohara T.

Am J Cardiol. 2019 Feb 1;123(3):361-367. doi: 10.1016/j.amjcard.2018.10.038. Epub 2018 Nov 6.

PMID:
30477803
13.

Disseminated dermatophytosis due to Nannizzia gypsea (Microsporum gypseum) in an elderly patient.

Demitsu T, Yamada T, Umemoto N, Kakurai M, Maeda T, Harada K, Kawase M.

J Dermatol. 2019 May;46(5):e169-e170. doi: 10.1111/1346-8138.14712. Epub 2018 Nov 23. No abstract available.

PMID:
30467900
14.

Ultrasonographic and radiological imaging demonstrating an anomalous origin of the left coronary artery causing acute coronary syndrome in an adolescent.

Taniguchi T, Umemoto N, Ishii H, Nakahata K, Shibata N, Mizutani T, Yamada M, Shimizu K, Murohara T.

J Cardiol Cases. 2018 Apr 1;17(4):141-145. doi: 10.1016/j.jccase.2017.12.008. eCollection 2018 Apr.

15.

Establishment of a modified CRISPR/Cas9 system with increased mutagenesis frequency using the translational enhancer dMac3 and multiple guide RNAs in potato.

Kusano H, Ohnuma M, Mutsuro-Aoki H, Asahi T, Ichinosawa D, Onodera H, Asano K, Noda T, Horie T, Fukumoto K, Kihira M, Teramura H, Yazaki K, Umemoto N, Muranaka T, Shimada H.

Sci Rep. 2018 Sep 13;8(1):13753. doi: 10.1038/s41598-018-32049-2.

16.

Third DWF1 paralog in Solanaceae, sterol Δ24-isomerase, branches withanolide biosynthesis from the general phytosterol pathway.

Knoch E, Sugawara S, Mori T, Poulsen C, Fukushima A, Harholt J, Fujimoto Y, Umemoto N, Saito K.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8096-E8103. doi: 10.1073/pnas.1807482115. Epub 2018 Aug 6.

17.

Mycoplasma pneumoniae-associated mucositis with severe blistering stomatitis and pneumonia successfully treated with azithromycin and infusion therapy.

Demitsu T, Kawase M, Nagashima K, Takazawa M, Yamada T, Kakurai M, Umemoto N, Jinbu Y.

J Dermatol. 2019 Jan;46(1):e38-e39. doi: 10.1111/1346-8138.14510. Epub 2018 Jun 28. No abstract available.

PMID:
29952018
18.

Comparative analysis of CYP716A subfamily enzymes for the heterologous production of C-28 oxidized triterpenoids in transgenic yeast.

Suzuki H, Fukushima EO, Umemoto N, Ohyama K, Seki H, Muranaka T.

Plant Biotechnol (Tokyo). 2018 Jun 25;35(2):131-139. doi: 10.5511/plantbiotechnology.18.0416a.

19.

The lactate clearance calculated using serum lactate level 6 h after is an important prognostic predictor after extracorporeal cardiopulmonary resuscitation: a single-center retrospective observational study.

Mizutani T, Umemoto N, Taniguchi T, Ishii H, Hiramatsu Y, Arata K, Takuya H, Inoue S, Sugiura T, Asai T, Yamada M, Murohara T, Shimizu K.

J Intensive Care. 2018 Jun 1;6:33. doi: 10.1186/s40560-018-0302-z. eCollection 2018. Erratum in: J Intensive Care. 2019 Mar 21;7:18.

20.

Generation of α-solanine-free hairy roots of potato by CRISPR/Cas9 mediated genome editing of the St16DOX gene.

Nakayasu M, Akiyama R, Lee HJ, Osakabe K, Osakabe Y, Watanabe B, Sugimoto Y, Umemoto N, Saito K, Muranaka T, Mizutani M.

Plant Physiol Biochem. 2018 Oct;131:70-77. doi: 10.1016/j.plaphy.2018.04.026. Epub 2018 Apr 24.

PMID:
29735370
21.

Long-term clinical outcomes after coronary artery bypass graft versus everolimus-eluting stent implantation in chronic hemodialysis patients.

Kumada Y, Ishii H, Aoyama T, Kamoi D, Sakakibara T, Umemoto N, Ito R, Takahashi H, Murohara T.

Coron Artery Dis. 2018 Sep;29(6):489-494. doi: 10.1097/MCA.0000000000000628.

PMID:
29668554
22.

Case of pyoderma gangrenosum-like sporotrichosis caused by Sporothrix globosa in a patient with ulcerative colitis.

Takazawa M, Harada K, Kakurai M, Yamada T, Umemoto N, Sakai T, Maeda T, Kawase M, Demitsu T.

J Dermatol. 2018 Aug;45(8):e226-e227. doi: 10.1111/1346-8138.14276. Epub 2018 Feb 27. No abstract available.

PMID:
29488248
23.

Dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid in a patient with acquired reactive perforating collagenosis.

Maki N, Nishie W, Takazawa M, Kakurai M, Yamada T, Umemoto N, Kawase M, Izumi K, Shimizu H, Demitsu T.

J Dermatol. 2018 May;45(5):600-602. doi: 10.1111/1346-8138.14254. Epub 2018 Feb 14.

PMID:
29446164
24.

Clinical Outcomes after Isolated Infrapopliteal Revascularization in Hemodialysis Patients with Critical Limb Ischemia: Endovascular Therapy versus Bypass Surgery.

Ito R, Kumada Y, Ishii H, Kamoi D, Sakakibara T, Umemoto N, Takahashi H, Murihara T.

J Atheroscler Thromb. 2018 Sep 1;25(9):799-807. doi: 10.5551/jat.42648. Epub 2018 Jan 23.

25.

Crystal structure and thermodynamic dissection of chitin oligosaccharide binding to the LysM module of chitinase-A from Pteris ryukyuensis.

Ohnuma T, Taira T, Umemoto N, Kitaoku Y, Sørlie M, Numata T, Fukamizo T.

Biochem Biophys Res Commun. 2017 Dec 16;494(3-4):736-741. doi: 10.1016/j.bbrc.2017.08.143. Epub 2017 Sep 1.

PMID:
28867184
26.

A Dioxygenase Catalyzes Steroid 16α-Hydroxylation in Steroidal Glycoalkaloid Biosynthesis.

Nakayasu M, Umemoto N, Ohyama K, Fujimoto Y, Lee HJ, Watanabe B, Muranaka T, Saito K, Sugimoto Y, Mizutani M.

Plant Physiol. 2017 Sep;175(1):120-133. doi: 10.1104/pp.17.00501. Epub 2017 Jul 28.

27.

Disseminated extrafacial rosacea with papulonecrotic lesions.

Demitsu T, Tsukahara R, Umemoto N, Nakamura S, Nagashima K, Yamada T, Kakurai M, Tanaka Y, Kakehashi A, Miyata T.

J Dermatol Case Rep. 2016 Dec 31;10(4):68-72. doi: 10.3315/jdcr.2016.1236. eCollection 2016 Dec 31.

28.

The Association of Ankle Brachial Index, Protein-Energy Wasting, and Inflammation Status with Cardiovascular Mortality in Patients on Chronic Hemodialysis.

Ishii H, Takahashi H, Ito Y, Aoyama T, Kamoi D, Sakakibara T, Umemoto N, Kumada Y, Suzuki S, Murohara T.

Nutrients. 2017 Apr 21;9(4). pii: E416. doi: 10.3390/nu9040416.

29.

Comparative Characterization of the Leaf Tissue of Physalis alkekengi and Physalis peruviana Using RNA-seq and Metabolite Profiling.

Fukushima A, Nakamura M, Suzuki H, Yamazaki M, Knoch E, Mori T, Umemoto N, Morita M, Hirai G, Sodeoka M, Saito K.

Front Plant Sci. 2016 Dec 20;7:1883. doi: 10.3389/fpls.2016.01883. eCollection 2016.

30.

Bypass Surgery Versus Endovascular Therapy in Chronic Hemodialysis Patients With CLI Due to Infrainguinal Disease.

Kumada Y, Ishii H, Aoyama T, Kamoi D, Sakakibara T, Umemoto N, Suzuki S, Takahashi H, Murohara T.

J Am Coll Cardiol. 2016 Oct 4;68(14):1601-2. doi: 10.1016/j.jacc.2016.07.736. No abstract available.

31.

Two Cytochrome P450 Monooxygenases Catalyze Early Hydroxylation Steps in the Potato Steroid Glycoalkaloid Biosynthetic Pathway.

Umemoto N, Nakayasu M, Ohyama K, Yotsu-Yamashita M, Mizutani M, Seki H, Saito K, Muranaka T.

Plant Physiol. 2016 Aug;171(4):2458-67. doi: 10.1104/pp.16.00137. Epub 2016 Jun 15.

32.

Reverse association of omega-3/omega-6 polyunsaturated fatty acids ratios with carotid atherosclerosis in patients on hemodialysis.

Umemoto N, Ishii H, Kamoi D, Aoyama T, Sakakibara T, Takahashi H, Tanaka A, Yasuda Y, Suzuki S, Matsubara T, Murohara T.

Atherosclerosis. 2016 Jun;249:65-9. doi: 10.1016/j.atherosclerosis.2016.03.037. Epub 2016 Apr 1.

PMID:
27065243
33.

Corrigendum to "Zinc finger MYND-type containing 8 promotes tumour angiogenesis via induction of vascular endothelial growth factor-A expression" [FEBS Lett. 588 (2014) 3409-3416].

Kuroyanagi J, Shimada Y, Zhang B, Ariyoshi M, Umemoto N, Nishimura Y, Tanaka T.

FEBS Lett. 2015 Mar 24;589(7):870. doi: 10.1016/j.febslet.2015.02.010. No abstract available.

34.

Possible paraneoplastic syndrome case of bullous pemphigoid with immunoglobulin G anti-BP180 C-terminal domain antibodies associated with psoriasis and primary macroglobulinemia.

Maki N, Demitsu T, Umemoto N, Nagashima K, Nakamura T, Kakurai M, Nakamura S, Yamada T, Ishii N, Hashimoto T.

J Dermatol. 2016 May;43(5):571-4. doi: 10.1111/1346-8138.13170. Epub 2015 Oct 28.

PMID:
26507447
35.

Modulation of the transglycosylation activity of plant family GH18 chitinase by removing or introducing a tryptophan side chain.

Umemoto N, Ohnuma T, Osawa T, Numata T, Fukamizo T.

FEBS Lett. 2015 Aug 19;589(18):2327-33. doi: 10.1016/j.febslet.2015.07.018. Epub 2015 Jul 26.

36.

Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis.

Westcot SE, Hatzold J, Urban MD, Richetti SK, Skuster KJ, Harm RM, Lopez Cervera R, Umemoto N, McNulty MS, Clark KJ, Hammerschmidt M, Ekker SC.

PLoS One. 2015 Jun 25;10(6):e0130688. doi: 10.1371/journal.pone.0130688. eCollection 2015.

37.

Treatment with cilostazol improves clinical outcome after endovascular therapy in hemodialysis patients with peripheral artery disease.

Ishii H, Aoyama T, Takahashi H, Kumada Y, Kamoi D, Sakakibara T, Umemoto N, Suzuki S, Tanaka A, Ito Y, Murohara T.

J Cardiol. 2016 Feb;67(2):199-204. doi: 10.1016/j.jjcc.2015.05.003. Epub 2015 Jun 11.

38.

E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish.

Shimada Y, Kuninaga S, Ariyoshi M, Zhang B, Shiina Y, Takahashi Y, Umemoto N, Nishimura Y, Enari H, Tanaka T.

Nutr Metab (Lond). 2015 May 20;12:17. doi: 10.1186/s12986-015-0012-7. eCollection 2015.

39.

A class III chitinase without disulfide bonds from the fern, Pteris ryukyuensis: crystal structure and ligand-binding studies.

Kitaoku Y, Umemoto N, Ohnuma T, Numata T, Taira T, Sakuda S, Fukamizo T.

Planta. 2015 Oct;242(4):895-907. doi: 10.1007/s00425-015-2330-4. Epub 2015 May 22.

PMID:
25998529
40.

Cheek and periorbital peculiar discoid lupus erythematosus: rare clinical presentation mimicking tinea faciei, cutaneous granulomatous disease or blepharitis.

Nakamura S, Yamada T, Umemoto N, Nakamura T, Wakatabi K, Iida E, Masaki M, Kakurai M, Demitsu T.

Case Rep Dermatol. 2015 Apr 9;7(1):56-60. doi: 10.1159/000381208. eCollection 2015 Jan-Apr.

41.

In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3).

Zhang B, Shimada Y, Kuroyanagi J, Ariyoshi M, Nomoto T, Shintou T, Umemoto N, Nishimura Y, Miyazaki T, Tanaka T.

Biomaterials. 2015 Jun;52:14-25. doi: 10.1016/j.biomaterials.2015.02.009. Epub 2015 Feb 21.

PMID:
25818410
42.

Rapidly progressing squamous cell carcinoma (SCC) on the scrotum following cerebral infarction likely due to cardiac metastasis of SCC: a case report.

Nakamura T, Nakamura S, Nagashima K, Maki N, Iida E, Umemoto N, Yamada T, Nakano T, Endo S, Umemoto T, Demitsu T.

J Eur Acad Dermatol Venereol. 2016 May;30(5):887-8. doi: 10.1111/jdv.13053. Epub 2015 Feb 24. No abstract available.

PMID:
25712571
43.

Keloidal basal cell carcinoma possibly developed from classical nodulo-ulcerative type of basal cell carcinoma: report of a case.

Nagashima K, Demitsu T, Nakamura T, Nakamura S, Yamada T, Kakurai M, Umemoto N, Dohmoto T, Imagawa I, Yoneda K.

J Dermatol. 2015 Apr;42(4):427-9. doi: 10.1111/1346-8138.12796. Epub 2015 Feb 16. No abstract available.

PMID:
25689028
44.

Crystal structures and inhibitor binding properties of plant class V chitinases: the cycad enzyme exhibits unique structural and functional features.

Umemoto N, Kanda Y, Ohnuma T, Osawa T, Numata T, Sakuda S, Taira T, Fukamizo T.

Plant J. 2015 Apr;82(1):54-66. doi: 10.1111/tpj.12785. Epub 2015 Mar 1.

45.

Downregulation of stanniocalcin 1 is responsible for sorafenib-induced cardiotoxicity.

Kawabata M, Umemoto N, Shimada Y, Nishimura Y, Zhang B, Kuroyanagi J, Miyabe M, Tanaka T.

Toxicol Sci. 2015 Feb;143(2):374-84. doi: 10.1093/toxsci/kfu235. Epub 2014 Nov 3.

PMID:
25370841
46.

Sterol side chain reductase 2 is a key enzyme in the biosynthesis of cholesterol, the common precursor of toxic steroidal glycoalkaloids in potato.

Sawai S, Ohyama K, Yasumoto S, Seki H, Sakuma T, Yamamoto T, Takebayashi Y, Kojima M, Sakakibara H, Aoki T, Muranaka T, Saito K, Umemoto N.

Plant Cell. 2014 Sep;26(9):3763-74. doi: 10.1105/tpc.114.130096. Epub 2014 Sep 12.

47.

Zebrafish xenotransplantation model for cancer stem-like cell study and high-throughput screening of inhibitors.

Zhang B, Shimada Y, Kuroyanagi J, Nishimura Y, Umemoto N, Nomoto T, Shintou T, Miyazaki T, Tanaka T.

Tumour Biol. 2014 Dec;35(12):11861-9. doi: 10.1007/s13277-014-2417-8. Epub 2014 Sep 11.

PMID:
25209178
48.

Zinc finger MYND-type containing 8 promotes tumour angiogenesis via induction of vascular endothelial growth factor-A expression.

Kuroyanagi J, Shimada Y, Zhang B, Ariyoshi M, Umemoto N, Nishimura Y, Tanaka T.

FEBS Lett. 2014 Sep 17;588(18):3409-16. doi: 10.1016/j.febslet.2014.07.033. Epub 2014 Aug 10. Erratum in: FEBS Lett. 2014 Nov 28;588(23):4526. FEBS Lett. 2015 Mar 24;589(7):870.

49.

Zebrafish as a systems toxicology model for developmental neurotoxicity testing.

Nishimura Y, Murakami S, Ashikawa Y, Sasagawa S, Umemoto N, Shimada Y, Tanaka T.

Congenit Anom (Kyoto). 2015 Feb;55(1):1-16. doi: 10.1111/cga.12079. Review.

PMID:
25109898
50.

Physicochemical properties of oleic acid-based partially fluorinated gemini surfactants.

Sakai K, Umemoto N, Aburai K, Takamatsu Y, Endo T, Kitiyanan B, Matsumoto M, Sakai H, Abe M.

J Oleo Sci. 2014;63(3):257-67.

PMID:
24712085

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