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Items: 29

1.

Antibody-based methods for the measurement of α-synuclein concentration in human cerebrospinal fluid - method comparison and round robin study.

Mollenhauer B, Bowman FD, Drake D, Duong J, Blennow K, El-Agnaf O, Shaw LM, Masucci J, Taylor P, Umek RM, Dunty JM, Smith CL, Stoops E, Vanderstichele H, Schmid AW, Moniatte M, Zhang J, Kruse N, Lashuel HA, Teunissen C, Schubert T, Dave KD, Hutten SJ, Zetterberg H.

J Neurochem. 2019 Apr;149(1):126-138. doi: 10.1111/jnc.14569. Epub 2018 Nov 13.

2.

Commutability of the certified reference materials for the standardization of β-amyloid 1-42 assay in human cerebrospinal fluid: lessons for tau and β-amyloid 1-40 measurements.

Andreasson U, Kuhlmann J, Pannee J, Umek RM, Stoops E, Vanderstichele H, Matzen A, Vandijck M, Dauwe M, Leinenbach A, Rutz S, Portelius E, Zegers I, Zetterberg H, Blennow K.

Clin Chem Lab Med. 2018 Nov 27;56(12):2058-2066. doi: 10.1515/cclm-2018-0147.

PMID:
29949507
3.

A user's guide for α-synuclein biomarker studies in biological fluids: Perianalytical considerations.

Mollenhauer B, Batrla R, El-Agnaf O, Galasko DR, Lashuel HA, Merchant KM, Shaw LM, Selkoe DJ, Umek R, Vanderstichele H, Zetterberg H, Zhang J, Caspell-Garcia C, Coffey C, Hutten SJ, Frasier M, Taylor P; Investigating Synuclein Consortium of the Michael J. Fox Foundation for Parkinson's Research.

Mov Disord. 2017 Aug;32(8):1117-1130. doi: 10.1002/mds.27090. Epub 2017 Jul 22. Review.

4.

Cerebrospinal Fluid Biomarkers for Alzheimer's Disease: A View of the Regulatory Science Qualification Landscape from the Coalition Against Major Diseases CSF Biomarker Team.

Arnerić SP, Batrla-Utermann R, Beckett L, Bittner T, Blennow K, Carter L, Dean R, Engelborghs S, Genius J, Gordon MF, Hitchcock J, Kaplow J, Luthman J, Meibach R, Raunig D, Romero K, Samtani MN, Savage M, Shaw L, Stephenson D, Umek RM, Vanderstichele H, Willis B, Yule S.

J Alzheimers Dis. 2017;55(1):19-35. Review.

5.

Assessing the commutability of reference material formats for the harmonization of amyloid-β measurements.

Bjerke M, Andreasson U, Kuhlmann J, Portelius E, Pannee J, Lewczuk P, Umek RM, Vanmechelen E, Vanderstichele H, Stoops E, Lewis J, Vandijck M, Kostanjevecki V, Jeromin A, Salamone SJ, Schmidt O, Matzen A, Madin K, Eichenlaub U, Bittner T, Shaw LM, Zegers I, Zetterberg H, Blennow K.

Clin Chem Lab Med. 2016 Jul 1;54(7):1177-91. doi: 10.1515/cclm-2015-0733.

6.

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research.

O'Bryant SE, Gupta V, Henriksen K, Edwards M, Jeromin A, Lista S, Bazenet C, Soares H, Lovestone S, Hampel H, Montine T, Blennow K, Foroud T, Carrillo M, Graff-Radford N, Laske C, Breteler M, Shaw L, Trojanowski JQ, Schupf N, Rissman RA, Fagan AM, Oberoi P, Umek R, Weiner MW, Grammas P, Posner H, Martins R; STAR-B and BBBIG working groups.

Alzheimers Dement. 2015 May;11(5):549-60. doi: 10.1016/j.jalz.2014.08.099. Epub 2014 Oct 1. Review.

7.

Global standardization measurement of cerebral spinal fluid for Alzheimer's disease: an update from the Alzheimer's Association Global Biomarkers Consortium.

Carrillo MC, Blennow K, Soares H, Lewczuk P, Mattsson N, Oberoi P, Umek R, Vandijck M, Salamone S, Bittner T, Shaw LM, Stephenson D, Bain L, Zetterberg H.

Alzheimers Dement. 2013 Mar;9(2):137-40. doi: 10.1016/j.jalz.2012.11.003. Epub 2012 Dec 28.

PMID:
23274154
8.

Reference measurement procedures for Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches with focus on amyloid β42.

Mattsson N, Zegers I, Andreasson U, Bjerke M, Blankenstein MA, Bowser R, Carrillo MC, Gobom J, Heath T, Jenkins R, Jeromin A, Kaplow J, Kidd D, Laterza OF, Lockhart A, Lunn MP, Martone RL, Mills K, Pannee J, Ratcliffe M, Shaw LM, Simon AJ, Soares H, Teunissen CE, Verbeek MM, Umek RM, Vanderstichele H, Zetterberg H, Blennow K, Portelius E.

Biomark Med. 2012 Aug;6(4):409-17. doi: 10.2217/bmm.12.39. Review.

PMID:
22917143
9.

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers.

Mattsson N, Andreasson U, Persson S, Arai H, Batish SD, Bernardini S, Bocchio-Chiavetto L, Blankenstein MA, Carrillo MC, Chalbot S, Coart E, Chiasserini D, Cutler N, Dahlfors G, Duller S, Fagan AM, Forlenza O, Frisoni GB, Galasko D, Galimberti D, Hampel H, Handberg A, Heneka MT, Herskovits AZ, Herukka SK, Holtzman DM, Humpel C, Hyman BT, Iqbal K, Jucker M, Kaeser SA, Kaiser E, Kapaki E, Kidd D, Klivenyi P, Knudsen CS, Kummer MP, Lui J, Lladó A, Lewczuk P, Li QX, Martins R, Masters C, McAuliffe J, Mercken M, Moghekar A, Molinuevo JL, Montine TJ, Nowatzke W, O'Brien R, Otto M, Paraskevas GP, Parnetti L, Petersen RC, Prvulovic D, de Reus HP, Rissman RA, Scarpini E, Stefani A, Soininen H, Schröder J, Shaw LM, Skinningsrud A, Skrogstad B, Spreer A, Talib L, Teunissen C, Trojanowski JQ, Tumani H, Umek RM, Van Broeck B, Vanderstichele H, Vecsei L, Verbeek MM, Windisch M, Zhang J, Zetterberg H, Blennow K.

Alzheimers Dement. 2011 Jul;7(4):386-395.e6. doi: 10.1016/j.jalz.2011.05.2243. Erratum in: Alzheimers Dement. 2011 Sep;7(5):556.

10.

Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease.

Zetterberg H, Andreasson U, Hansson O, Wu G, Sankaranarayanan S, Andersson ME, Buchhave P, Londos E, Umek RM, Minthon L, Simon AJ, Blennow K.

Arch Neurol. 2008 Aug;65(8):1102-7. doi: 10.1001/archneur.65.8.1102.

PMID:
18695061
11.

Electronic detection of nucleic acids: a versatile platform for molecular diagnostics.

Umek RM, Lin SW, Vielmetter J, Terbrueggen RH, Irvine B, Yu CJ, Kayyem JF, Yowanto H, Blackburn GF, Farkas DH, Chen YP.

J Mol Diagn. 2001 May;3(2):74-84.

12.

Bioelectronic detection of point mutations using discrimination of the H63D polymorphism of the Hfe gene as a model.

Umek RM, Lin SS, Chen Yp Y, Irvine B, Paulluconi G, Chan V, Chong Y, Cheung L, Vielmetter J, Farkas DH.

Mol Diagn. 2000 Dec;5(4):321-8.

PMID:
11172496
13.

C/EBPalpha is required to maintain postmitotic growth arrest in adipocytes.

Tao H, Umek RM.

DNA Cell Biol. 2000 Jan;19(1):9-18.

PMID:
10668787
14.
15.

Reciprocal regulation of gadd45 by C/EBP alpha and c-Myc.

Tao H, Umek RM.

DNA Cell Biol. 1999 Jan;18(1):75-84.

PMID:
10025511
16.
17.

C/EBPalpha regulation of the growth-arrest-associated gene gadd45.

Constance CM, Morgan JI 4th, Umek RM.

Mol Cell Biol. 1996 Jul;16(7):3878-83.

18.

Differential expression of gas and gadd genes at distinct growth arrest points during adipocyte development.

Shugart EC, Levenson AS, Constance CM, Umek RM.

Cell Growth Differ. 1995 Dec;6(12):1541-7.

19.

Adjuvant therapy for breast cancer.

Farkas DH, Umek RM.

N Engl J Med. 1994 Sep 15;331(11):743; author reply 745-6. No abstract available.

PMID:
7914674
20.

Improved quantitation of HER-2/neu gene copy number in breast tumor-derived DNA samples.

Farkas DH, McMahon LW, Cai P, Umek RM.

Am J Clin Pathol. 1993 Oct;100(4):444-50.

PMID:
8105677
21.

Ease of DNA unwinding is a conserved property of yeast replication origins.

Natale DA, Umek RM, Kowalski D.

Nucleic Acids Res. 1993 Feb 11;21(3):555-60.

23.
24.

CCAAT-enhancer binding protein: a component of a differentiation switch.

Umek RM, Friedman AD, McKnight SL.

Science. 1991 Jan 18;251(4991):288-92. Review.

PMID:
1987644
26.

Thermal energy suppresses mutational defects in DNA unwinding at a yeast replication origin.

Umek RM, Kowalski D.

Proc Natl Acad Sci U S A. 1990 Apr;87(7):2486-90.

27.

New beginnings in studies of eukaryotic DNA replication origins.

Umek RM, Linskens MH, Kowalski D, Huberman JA.

Biochim Biophys Acta. 1989 Jan 23;1007(1):1-14. Review. No abstract available.

PMID:
2642383
28.
29.

Yeast regulatory sequences preferentially adopt a non-B conformation in supercoiled DNA.

Umek RM, Kowalski D.

Nucleic Acids Res. 1987 Jun 11;15(11):4467-80.

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