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Impact of CPAP on Forehead Near-infrared Spectroscopy Measurements in Patients With Acute Respiratory Failure: Truth or Illusion.

Doerr C, Kietaibl C, Doerr K, Hagmann M, Baumann L, Kimberger O, Ullrich R, Markstaller K, Klein KU.

J Neurosurg Anesthesiol. 2018 Jul 13. doi: 10.1097/ANA.0000000000000529. [Epub ahead of print]


Synergistic anti-angiogenic treatment effects by dual FGFR1 and VEGFR1 inhibition in FGFR1-amplified breast cancer.

Golfmann K, Meder L, Koker M, Volz C, Borchmann S, Tharun L, Dietlein F, Malchers F, Florin A, Büttner R, Rosen N, Rodrik-Outmezguine V, Hallek M, Ullrich RT.

Oncogene. 2018 Jul 3. doi: 10.1038/s41388-018-0380-3. [Epub ahead of print]


Combined VEGF and PD-L1 Blockade Displays Synergistic Treatment Effects in an Autochthonous Mouse Model of Small Cell Lung Cancer.

Meder L, Schuldt P, Thelen M, Schmitt A, Dietlein F, Klein S, Borchmann S, Wennhold K, Vlasic I, Oberbeck S, Riedel R, Florin A, Golfmann K, Schlößer HA, Odenthal M, Buettner R, Wolf J, Hallek M, Herling M, von Bergwelt-Baildon M, Reinhardt HC, Ullrich RT.

Cancer Res. 2018 Aug 1;78(15):4270-4281. doi: 10.1158/0008-5472.CAN-17-2176. Epub 2018 May 18.


Simultaneous Presence of Non- and Highly Mutated Keyhole Limpet Hemocyanin (KLH)-Specific Plasmablasts Early after Primary KLH Immunization Suggests Cross-Reactive Memory B Cell Activation.

Giesecke C, Meyer T, Durek P, Maul J, Preiß J, Jacobs JFM, Thiel A, Radbruch A, Ullrich R, Dörner T.

J Immunol. 2018 Jun 15;200(12):3981-3992. doi: 10.4049/jimmunol.1701728. Epub 2018 May 7.


HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types.

Zirkel A, Nikolic M, Sofiadis K, Mallm JP, Brackley CA, Gothe H, Drechsel O, Becker C, Altmüller J, Josipovic N, Georgomanolis T, Brant L, Franzen J, Koker M, Gusmao EG, Costa IG, Ullrich RT, Wagner W, Roukos V, Nürnberg P, Marenduzzo D, Rippe K, Papantonis A.

Mol Cell. 2018 May 17;70(4):730-744.e6. doi: 10.1016/j.molcel.2018.03.030. Epub 2018 Apr 26.


Self-sustained enzymatic cascade for the production of 2,5-furandicarboxylic acid from 5-methoxymethylfurfural.

Carro J, Fernández-Fueyo E, Fernández-Alonso C, Cañada J, Ullrich R, Hofrichter M, Alcalde M, Ferreira P, Martínez AT.

Biotechnol Biofuels. 2018 Apr 2;11:86. doi: 10.1186/s13068-018-1091-2. eCollection 2018.


Side chain removal from corticosteroids by unspecific peroxygenase.

Ullrich R, Poraj-Kobielska M, Scholze S, Halbout C, Sandvoss M, Pecyna MJ, Scheibner K, Hofrichter M.

J Inorg Biochem. 2018 Jun;183:84-93. doi: 10.1016/j.jinorgbio.2018.03.011. Epub 2018 Mar 26.


Recent advances in understanding acute respiratory distress syndrome.

Wohlrab P, Kraft F, Tretter V, Ullrich R, Markstaller K, Klein KU.

F1000Res. 2018 Mar 5;7. pii: F1000 Faculty Rev-263. doi: 10.12688/f1000research.11148.1. eCollection 2018. Review.


LIN28B enhanced tumorigenesis in an autochthonous KRASG12V-driven lung carcinoma mouse model.

Meder L, König K, Dietlein F, Macheleidt I, Florin A, Ercanoglu MS, Rommerscheidt-Fuss U, Koker M, Schön G, Odenthal M, Klein F, Büttner R, Schulte JH, Heukamp LC, Ullrich RT.

Oncogene. 2018 May;37(20):2746-2756. doi: 10.1038/s41388-018-0158-7. Epub 2018 Mar 5.


R. J. Michael Fry, MD 1925-2017.

Boice JD Jr, Kronenberg A, Ullrich RL.

Radiat Res. 2018 Jan;189(1):1-4. doi: 10.1667/RRRJMF.1. No abstract available.


Enzymatic Preparation of 2,5-Furandicarboxylic Acid (FDCA)-A Substitute of Terephthalic Acid-By the Joined Action of Three Fungal Enzymes.

Karich A, Kleeberg SB, Ullrich R, Hofrichter M.

Microorganisms. 2018 Jan 9;6(1). pii: E5. doi: 10.3390/microorganisms6010005.


Incidence of hyperoxia and related in-hospital mortality in critically ill patients: a retrospective data analysis.

Kraft F, Andel H, Gamper J, Markstaller K, Ullrich R, Klein KU.

Acta Anaesthesiol Scand. 2018 Mar;62(3):347-356. doi: 10.1111/aas.13047. Epub 2017 Dec 6.


Fatty Acid Chain Shortening by a Fungal Peroxygenase.

Olmedo A, Río JCD, Kiebist J, Ullrich R, Hofrichter M, Scheibner K, Martínez AT, Gutiérrez A.

Chemistry. 2017 Dec 1;23(67):16985-16989. doi: 10.1002/chem.201704773. Epub 2017 Nov 20.


Treatment of primary graft dysfunction after lung transplantation with orally inhaled AP301: A prospective, randomized pilot study.

Aigner C, Slama A, Barta M, Mitterbauer A, Lang G, Taghavi S, Matilla J, Ullrich R, Krenn K, Jaksch P, Markstaller K, Klepetko W.

J Heart Lung Transplant. 2017 Sep 30. pii: S1053-2498(17)32036-3. doi: 10.1016/j.healun.2017.09.021. [Epub ahead of print]


Analysis of region specific gene expression patterns in the heart and systemic responses after experimental myocardial ischemia.

Zimmermann M, Beer L, Ullrich R, Lukovic D, Simader E, Traxler D, Wagner T, Nemec L, Altenburger L, Zuckermann A, Gyöngyösi M, Ankersmit HJ, Mildner M.

Oncotarget. 2017 May 17;8(37):60809-60825. doi: 10.18632/oncotarget.17955. eCollection 2017 Sep 22.


Fungal Unspecific Peroxygenases Oxidize the Majority of Organic EPA Priority Pollutants.

Karich A, Ullrich R, Scheibner K, Hofrichter M.

Front Microbiol. 2017 Aug 9;8:1463. doi: 10.3389/fmicb.2017.01463. eCollection 2017.


Inhaled AP301 for treatment of pulmonary edema in mechanically ventilated patients with acute respiratory distress syndrome: a phase IIa randomized placebo-controlled trial.

Krenn K, Lucas R, Croizé A, Boehme S, Klein KU, Hermann R, Markstaller K, Ullrich R.

Crit Care. 2017 Jul 27;21(1):194. doi: 10.1186/s13054-017-1795-x.


Oxidoreductases on their way to industrial biotransformations.

Martínez AT, Ruiz-Dueñas FJ, Camarero S, Serrano A, Linde D, Lund H, Vind J, Tovborg M, Herold-Majumdar OM, Hofrichter M, Liers C, Ullrich R, Scheibner K, Sannia G, Piscitelli A, Pezzella C, Sener ME, Kılıç S, van Berkel WJH, Guallar V, Lucas MF, Zuhse R, Ludwig R, Hollmann F, Fernández-Fueyo E, Record E, Faulds CB, Tortajada M, Winckelmann I, Rasmussen JA, Gelo-Pujic M, Gutiérrez A, Del Río JC, Rencoret J, Alcalde M.

Biotechnol Adv. 2017 Nov 1;35(6):815-831. doi: 10.1016/j.biotechadv.2017.06.003. Epub 2017 Jun 15. Review.


Detection and differentiation of cerebral microemboli in patients undergoing major orthopaedic surgery using transcranial Doppler ultrasound.

Kietaibl C, Engel A, Horvat Menih I, Huepfl M, Erdoes G, Kubista B, Ullrich R, Windhager R, Markstaller K, Klein KU.

Br J Anaesth. 2017 Mar 1;118(3):400-406. doi: 10.1093/bja/aex001.


A Peroxygenase from Chaetomium globosum Catalyzes the Selective Oxygenation of Testosterone.

Kiebist J, Schmidtke KU, Zimmermann J, Kellner H, Jehmlich N, Ullrich R, Zänder D, Hofrichter M, Scheibner K.

Chembiochem. 2017 Mar 16;18(6):563-569. doi: 10.1002/cbic.201600677. Epub 2017 Mar 1.


Argon Preconditioning Protects Airway Epithelial Cells against Hydrogen Peroxide-Induced Oxidative Stress.

Hafner C, Qi H, Soto-Gonzalez L, Doerr K, Ullrich R, Tretter EV, Markstaller K, Klein KU.

Eur Surg Res. 2016;57(3-4):252-262. Epub 2016 Aug 25.


Long-term response to gluten-free diet as evidence for non-celiac wheat sensitivity in one third of patients with diarrhea-dominant and mixed-type irritable bowel syndrome.

Barmeyer C, Schumann M, Meyer T, Zielinski C, Zuberbier T, Siegmund B, Schulzke JD, Daum S, Ullrich R.

Int J Colorectal Dis. 2017 Jan;32(1):29-39. doi: 10.1007/s00384-016-2663-x. Epub 2016 Sep 30.


Hyperoxia Induces Inflammation and Cytotoxicity in Human Adult Cardiac Myocytes.

Hafner C, Wu J, Tiboldi A, Hess M, Mitulovic G, Kaun C, Krychtiuk KA, Wojta J, Ullrich R, Tretter EV, Markstaller K, Klein KU.

Shock. 2017 Apr;47(4):436-444. doi: 10.1097/SHK.0000000000000740.


Draft Genome Sequence of the Chloroperoxidase-Producing Fungus Caldariomyces fumago Woronichin DSM1256.

Kellner H, Pecyna MJ, Buchhaupt M, Ullrich R, Hofrichter M.

Genome Announc. 2016 Aug 4;4(4). pii: e00774-16. doi: 10.1128/genomeA.00774-16.


Retraction Notice to: Cytohesins Are Cytoplasmic ErbB Receptor Activators.

Bill A, Schmitz A, Albertoni B, Song JN, Heukamp LC, Walrafen D, Thorwirth F, Verveer PJ, Zimmer S, Meffert L, Schreiber A, Chatterjee S, Thomas RK, Ullrich RT, Lang T, Famulok M.

Cell. 2016 May 19;165(5):1293. doi: 10.1016/j.cell.2016.05.013. No abstract available.


When it rains, it pours: Peripartum cardiomyopathy with features of left-ventricular noncompaction in a hemodialysis patient.

Antlanger M, Kammerlander AA, Ullrich R, Haidinger M, Bonderman D, Mascherbauer J, Säemann MD.

Hemodial Int. 2016 Oct;20(4):E14-E17. doi: 10.1111/hdi.12427. Epub 2016 May 5.


Cerebral Gaseous Microemboli are Detectable During Continuous Venovenous Hemodialysis in Critically Ill Patients: An Observational Pilot Study.

Erdoes G, Kietaibl C, Boehme S, Ullrich R, Markstaller K, Eberle B, Klein KU.

J Neurosurg Anesthesiol. 2017 Jul;29(3):236-242. doi: 10.1097/ANA.0000000000000296.


Peroxygenase-Catalyzed Oxyfunctionalization Reactions Promoted by the Complete Oxidation of Methanol.

Ni Y, Fernández-Fueyo E, Gomez Baraibar A, Ullrich R, Hofrichter M, Yanase H, Alcalde M, van Berkel WJ, Hollmann F.

Angew Chem Int Ed Engl. 2016 Jan 11;55(2):798-801. doi: 10.1002/anie.201507881. Epub 2015 Nov 26.


Intermittent high-dose treatment with erlotinib enhances therapeutic efficacy in EGFR-mutant lung cancer.

Schöttle J, Chatterjee S, Volz C, Siobal M, Florin A, Rokitta D, Hinze Y, Dietlein F, Plenker D, König K, Albus K, Heuckmann JM, Rauh D, Franz T, Neumaier B, Fuhr U, Heukamp LC, Ullrich RT.

Oncotarget. 2015 Nov 17;6(36):38458-68. doi: 10.18632/oncotarget.6276.


Intermittent Hypoxia Causes Inflammation and Injury to Human Adult Cardiac Myocytes.

Wu J, Stefaniak J, Hafner C, Schramel JP, Kaun C, Wojta J, Ullrich R, Tretter VE, Markstaller K, Klein KU.

Anesth Analg. 2016 Feb;122(2):373-80. doi: 10.1213/ANE.0000000000001048.


Cyclic and constant hyperoxia cause inflammation, apoptosis and cell death in human umbilical vein endothelial cells.

Wu J, Hafner C, Schramel JP, Kaun C, Krychtiuk KA, Wojta J, Boehme S, Ullrich R, Tretter EV, Markstaller K, Klein KU.

Acta Anaesthesiol Scand. 2016 Apr;60(4):492-501. doi: 10.1111/aas.12646. Epub 2015 Oct 22.


Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity.

Kantara C, Moya SM, Houchen CW, Umar S, Ullrich RL, Singh P, Carney DH.

Lab Invest. 2015 Nov;95(11):1222-33. doi: 10.1038/labinvest.2015.103. Epub 2015 Aug 17.


The authors reply.

Boehme S, Baumgardner JE, Ullrich R, Markstaller K, David M.

Crit Care Med. 2015 Aug;43(8):e324-5. doi: 10.1097/CCM.0000000000001109. No abstract available.


Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts' Criteria.

Catassi C, Elli L, Bonaz B, Bouma G, Carroccio A, Castillejo G, Cellier C, Cristofori F, de Magistris L, Dolinsek J, Dieterich W, Francavilla R, Hadjivassiliou M, Holtmeier W, Körner U, Leffler DA, Lundin KE, Mazzarella G, Mulder CJ, Pellegrini N, Rostami K, Sanders D, Skodje GI, Schuppan D, Ullrich R, Volta U, Williams M, Zevallos VF, Zopf Y, Fasano A.

Nutrients. 2015 Jun 18;7(6):4966-77. doi: 10.3390/nu7064966.


Fungal unspecific peroxygenases: heme-thiolate proteins that combine peroxidase and cytochrome p450 properties.

Hofrichter M, Kellner H, Pecyna MJ, Ullrich R.

Adv Exp Med Biol. 2015;851:341-68. doi: 10.1007/978-3-319-16009-2_13. Review.


Real-time in-vivo imaging of pulmonary capillary perfusion using probe-based confocal laser scanning endomicroscopy in pigs: An interventional laboratory study.

Gruber S, Spielauer I, Böhme S, Baron D, Markstaller K, Ullrich R, Klein KU.

Eur J Anaesthesiol. 2015 Jun;32(6):392-9. doi: 10.1097/EJA.0000000000000260.


Steroid hydroxylation by basidiomycete peroxygenases: a combined experimental and computational study.

Babot ED, Del Río JC, Cañellas M, Sancho F, Lucas F, Guallar V, Kalum L, Lund H, Gröbe G, Scheibner K, Ullrich R, Hofrichter M, Martínez AT, Gutiérrez A.

Appl Environ Microbiol. 2015 Jun 15;81(12):4130-42. doi: 10.1128/AEM.00660-15. Epub 2015 Apr 10.


Preexisting antigen-specific immune responses are modulated by oral KLH feeding in humans.

Hostmann A, Meyer T, Maul J, Preiss J, Boortz B, Thiel A, Duchmann R, Ullrich R.

Eur J Immunol. 2015 Jul;45(7):1991-6. doi: 10.1002/eji.201445024. Epub 2015 Apr 27.


A report from the 2013 international symposium: the evaluation of the effects of low-dose radiation exposure in the life span study of atomic bomb survivors and other similar studies.

Grant EJ, Ozasa K, Ban N, de González AB, Cologne J, Cullings HM, Doi K, Furukawa K, Imaoka T, Kodama K, Nakamura N, Niwa O, Preston DL, Rajaraman P, Sadakane A, Saigusa S, Sakata R, Sobue T, Sugiyama H, Ullrich R, Wakeford R, Yasumura S, Milder CM, Shore RE.

Health Phys. 2015 May;108(5):551-6. doi: 10.1097/HP.0000000000000262.


Comments on Estimating Risks of Low Radiation Doses-A Critical Review of the BEIR VII Report and Its Use of the Linear No-Threshold (LNT) Hypothesis by Edward J. Calabrese and Michael K. O'Connor.

Crowley KD, Cullings HM, Landes RD, Shore RE, Ullrich RL.

Radiat Res. 2015 Apr;183(4):476-81. doi: 10.1667/RR4029.1. Epub 2015 Mar 25. No abstract available.


Oxidation and nitration of mononitrophenols by a DyP-type peroxidase.

Büttner E, Ullrich R, Strittmatter E, Piontek K, Plattner DA, Hofrichter M, Liers C.

Arch Biochem Biophys. 2015 May 15;574:86-92. doi: 10.1016/ Epub 2015 Mar 18.


Heme-thiolate ferryl of aromatic peroxygenase is basic and reactive.

Wang X, Ullrich R, Hofrichter M, Groves JT.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3686-91. doi: 10.1073/pnas.1503340112. Epub 2015 Mar 10.


Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data.

Fernandez-Cuesta L, Sun R, Menon R, George J, Lorenz S, Meza-Zepeda LA, Peifer M, Plenker D, Heuckmann JM, Leenders F, Zander T, Dahmen I, Koker M, Schöttle J, Ullrich RT, Altmüller J, Becker C, Nürnberg P, Seidel H, Böhm D, Göke F, Ansén S, Russell PA, Wright GM, Wainer Z, Solomon B, Petersen I, Clement JH, Sänger J, Brustugun OT, Helland Å, Solberg S, Lund-Iversen M, Buettner R, Wolf J, Brambilla E, Vingron M, Perner S, Haas SA, Thomas RK.

Genome Biol. 2015 Jan 5;16:7. doi: 10.1186/s13059-014-0558-0.


The toolbox of Auricularia auricula-judae dye-decolorizing peroxidase - Identification of three new potential substrate-interaction sites.

Strittmatter E, Serrer K, Liers C, Ullrich R, Hofrichter M, Piontek K, Schleicher E, Plattner DA.

Arch Biochem Biophys. 2015 May 15;574:75-85. doi: 10.1016/ Epub 2014 Dec 23.


Space radiation-associated lung injury in a murine model.

Christofidou-Solomidou M, Pietrofesa RA, Arguiri E, Schweitzer KS, Berdyshev EV, McCarthy M, Corbitt A, Alwood JS, Yu Y, Globus RK, Solomides CC, Ullrich RL, Petrache I.

Am J Physiol Lung Cell Mol Physiol. 2015 Mar 1;308(5):L416-28. doi: 10.1152/ajplung.00260.2014. Epub 2014 Dec 19.


Influence of inspiration to expiration ratio on cyclic recruitment and derecruitment of atelectasis in a saline lavage model of acute respiratory distress syndrome.

Boehme S, Bentley AH, Hartmann EK, Chang S, Erdoes G, Prinzing A, Hagmann M, Baumgardner JE, Ullrich R, Markstaller K, David M.

Crit Care Med. 2015 Mar;43(3):e65-74. doi: 10.1097/CCM.0000000000000788.


5-hydroxymethylfurfural conversion by fungal aryl-alcohol oxidase and unspecific peroxygenase.

Carro J, Ferreira P, Rodríguez L, Prieto A, Serrano A, Balcells B, Ardá A, Jiménez-Barbero J, Gutiérrez A, Ullrich R, Hofrichter M, Martínez AT.

FEBS J. 2015 Aug;282(16):3218-29. doi: 10.1111/febs.13177. Epub 2015 Jan 8.


Extracorporeal CO2 removal as bridge to lung transplantation in life-threatening hypercapnia.

Schellongowski P, Riss K, Staudinger T, Ullrich R, Krenn CG, Sitzwohl C, Bojic A, Wohlfarth P, Sperr WR, Rabitsch W, Aigner C, Taghavi S, Jaksch P, Klepetko W, Lang G.

Transpl Int. 2015 Mar;28(3):297-304. doi: 10.1111/tri.12486. Epub 2014 Dec 5.


Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/metastasis.

Kantara C, O'Connell MR, Luthra G, Gajjar A, Sarkar S, Ullrich RL, Singh P.

Lab Invest. 2015 Jan;95(1):100-12. doi: 10.1038/labinvest.2014.133. Epub 2014 Oct 27.


Changing the hemoglobin A1c goals for children with type 1 diabetes.

Ullrich RL, Chase HP.

Diabetes Technol Ther. 2014 Oct;16(10):611-2. doi: 10.1089/dia.2014.0219. No abstract available.


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