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Items: 1 to 50 of 58

1.

Multivalent assembly of a pyrene functionalized thio-N-acetylglucosamine: Synthesis, spectroscopic and WGA binding studies.

Montenegro HO, Di Chenna PH, Spagnuolo CC, Uhrig ML.

Carbohydr Res. 2019 Jun 1;479:6-12. doi: 10.1016/j.carres.2019.04.010. Epub 2019 Apr 30.

PMID:
31078936
2.

Trypanosoma cruzi trans-sialidase alternative substrates: Study of the effect of substitution in C-6 in benzyl β-lactoside.

Morrone-Pozzuto P, Uhrig ML, Agusti R.

Carbohydr Res. 2019 May 15;478:33-45. doi: 10.1016/j.carres.2019.04.003. Epub 2019 Apr 22.

PMID:
31054381
3.

Synthetic strategies for fluorination of carbohydrates.

Uhrig ML, Lantaño B, Postigo A.

Org Biomol Chem. 2019 May 29;17(21):5173-5189. doi: 10.1039/c9ob00405j. Review.

PMID:
31017598
4.

Towards context-sensitive CT imaging - organ-specific image formation for single (SECT) and dual energy computed tomography (DECT).

Dorn S, Chen S, Sawall S, Maier J, Knaup M, Uhrig M, Schlemmer HP, Maier A, Lell M, Kachelrieß M.

Med Phys. 2018 Oct;45(10):4541-4557. doi: 10.1002/mp.13127. Epub 2018 Aug 31.

PMID:
30098038
5.

Synthesis, molecular docking and biological evaluation of novel phthaloyl derivatives of 3-amino-3-aryl propionic acids as inhibitors of Trypanosoma cruzi trans-sialidase.

Kashif M, Chacón-Vargas KF, López-Cedillo JC, Nogueda-Torres B, Paz-González AD, Ramírez-Moreno E, Agusti R, Uhrig ML, Reyes-Arellano A, Peralta-Cruz J, Ashfaq M, Rivera G.

Eur J Med Chem. 2018 Aug 5;156:252-268. doi: 10.1016/j.ejmech.2018.07.005. Epub 2018 Jul 7.

PMID:
30006170
6.

Incidental pulmonary emboli in stage IV melanoma patients: Prevalence in CT staging examinations and improved detection with vessel reconstructions based on dual energy CT.

Uhrig M, Simons D, Schlemmer HP.

PLoS One. 2018 Jul 12;13(7):e0199458. doi: 10.1371/journal.pone.0199458. eCollection 2018.

7.

Impact of long-term androgen deprivation therapy on PSMA ligand PET/CT in patients with castration-sensitive prostate cancer.

Afshar-Oromieh A, Debus N, Uhrig M, Hope TA, Evans MJ, Holland-Letz T, Giesel FL, Kopka K, Hadaschik B, Kratochwil C, Haberkorn U.

Eur J Nucl Med Mol Imaging. 2018 Nov;45(12):2045-2054. doi: 10.1007/s00259-018-4079-z. Epub 2018 Jul 7.

8.

A Highly Sensitive Fluorogenic Probe for Imaging Glycoproteins and Mucine Activity in Live Cells in the Near-Infrared Region.

Samaniego Lopez C, Hebe Martínez J, Uhrig ML, Coluccio Leskow F, Spagnuolo CC.

Chemistry. 2018 Apr 25;24(24):6344-6348. doi: 10.1002/chem.201800790. Epub 2018 Apr 10.

PMID:
29512206
9.

Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis.

Matamala JM, Arias-Carrasco R, Sanchez C, Uhrig M, Bargsted L, Matus S, Maracaja-Coutinho V, Abarzua S, van Zundert B, Verdugo R, Manque P, Hetz C.

Neurobiol Aging. 2018 Apr;64:123-138. doi: 10.1016/j.neurobiolaging.2017.12.020. Epub 2017 Dec 29.

PMID:
29458840
10.

Corrigendum to "Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight" [Neurobiol. Aging 33 (2012) 831.e21-831.e31].

Amtul Z, Uhrig M, Wang L, Rozmahel RF, Beyreuther K.

Neurobiol Aging. 2018 Feb;62:247. doi: 10.1016/j.neurobiolaging.2017.12.007. No abstract available.

PMID:
29277188
11.

Improved detection of melanoma metastases by iodine maps from dual energy CT.

Uhrig M, Simons D, Bonekamp D, Schlemmer HP.

Eur J Radiol. 2017 May;90:27-33. doi: 10.1016/j.ejrad.2017.02.024. Epub 2017 Feb 17.

PMID:
28583644
12.

An in vitro and in vivo evaluation of new potential trans-sialidase inhibitors of Trypanosoma cruzi predicted by a computational drug repositioning method.

Lara-Ramirez EE, López-Cedillo JC, Nogueda-Torres B, Kashif M, Garcia-Perez C, Bocanegra-Garcia V, Agusti R, Uhrig ML, Rivera G.

Eur J Med Chem. 2017 May 26;132:249-261. doi: 10.1016/j.ejmech.2017.03.063. Epub 2017 Mar 28.

PMID:
28364659
13.

Synthesis of β-galactosylamides as ligands of the peanut lectin. Insights into the recognition process.

Cano ME, Varela O, García-Moreno MI, García Fernández JM, Kovensky J, Uhrig ML.

Carbohydr Res. 2017 Apr 18;443-444:58-67. doi: 10.1016/j.carres.2017.03.018. Epub 2017 Mar 23.

PMID:
28355582
14.

Advanced abdominal imaging with dual energy CT is feasible without increasing radiation dose.

Uhrig M, Simons D, Kachelrieß M, Pisana F, Kuchenbecker S, Schlemmer HP.

Cancer Imaging. 2016 Jun 21;16(1):15. doi: 10.1186/s40644-016-0073-5.

15.

Multivalent sialylation of β-thio-glycoclusters by Trypanosoma cruzi trans sialidase and analysis by high performance anion exchange chromatography.

Agustí R, Cano ME, Cagnoni AJ, Kovensky J, de Lederkremer RM, Uhrig ML.

Glycoconj J. 2016 Oct;33(5):809-18. doi: 10.1007/s10719-016-9676-0. Epub 2016 Jun 15.

PMID:
27306205
16.

High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer β-amyloid peptide.

Rauth S, Hinz D, Börger M, Uhrig M, Mayhaus M, Riemenschneider M, Skerra A.

Biochem J. 2016 Jun 1;473(11):1563-78. doi: 10.1042/BCJ20160114. Epub 2016 Mar 30.

17.

Emotion Elicitation: A Comparison of Pictures and Films.

Uhrig MK, Trautmann N, Baumgärtner U, Treede RD, Henrich F, Hiller W, Marschall S.

Front Psychol. 2016 Feb 17;7:180. doi: 10.3389/fpsyg.2016.00180. eCollection 2016.

18.

Culture shapes whether the pursuit of happiness predicts higher or lower well-being.

Ford BQ, Dmitrieva JO, Heller D, Chentsova-Dutton Y, Grossmann I, Tamir M, Uchida Y, Koopmann-Holm B, Floerke VA, Uhrig M, Bokhan T, Mauss IB.

J Exp Psychol Gen. 2015 Dec;144(6):1053-62. doi: 10.1037/xge0000108. Epub 2015 Sep 7.

19.

Diet and specific microbial exposure trigger features of environmental enteropathy in a novel murine model.

Brown EM, Wlodarska M, Willing BP, Vonaesch P, Han J, Reynolds LA, Arrieta MC, Uhrig M, Scholz R, Partida O, Borchers CH, Sansonetti PJ, Finlay BB.

Nat Commun. 2015 Aug 4;6:7806. doi: 10.1038/ncomms8806.

20.

Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labeling.

Samaniego Lopez C, Lago Huvelle MA, Uhrig ML, Coluccio Leskow F, Spagnuolo CC.

Chem Commun (Camb). 2015 Mar 21;51(23):4895-8. doi: 10.1039/c4cc10425k.

PMID:
25703604
21.

Histogram analysis of iodine maps from dual energy computed tomography for monitoring targeted therapy of melanoma patients.

Uhrig M, Simons D, Ganten MK, Hassel JC, Schlemmer HP.

Future Oncol. 2015;11(4):591-606. doi: 10.2217/fon.14.265.

PMID:
25686115
22.

Synthesis of divalent ligands of β-thio- and β-N-galactopyranosides and related lactosides and their evaluation as substrates and inhibitors of Trypanosoma cruzi trans-sialidase.

Cano ME, Agusti R, Cagnoni AJ, Tesoriero MF, Kovensky J, Uhrig ML, de Lederkremer RM.

Beilstein J Org Chem. 2014 Dec 19;10:3073-3086. doi: 10.3762/bjoc.10.324. eCollection 2014.

23.

Design and synthesis of hydrolytically stable multivalent ligands bearing thiodigalactoside analogues for peanut lectin and human galectin-3 binding.

Cagnoni AJ, Kovensky J, Uhrig ML.

J Org Chem. 2014 Jul 18;79(14):6456-67. doi: 10.1021/jo500883v. Epub 2014 Jun 25.

PMID:
24937526
24.

Monitoring targeted therapy using dual-energy CT: semi-automatic RECIST plus supplementary functional information by quantifying iodine uptake of melanoma metastases.

Uhrig M, Sedlmair M, Schlemmer HP, Hassel JC, Ganten M.

Cancer Imaging. 2013 Jul 22;13(3):306-13. doi: 10.1102/1470-7330.2013.0031.

25.

Synthesis and biological activity of divalent ligands based on 3-deoxy-4-thiolactose, an isosteric analogue of lactose.

Cagnoni AJ, Varela O, Kovensky J, Uhrig ML.

Org Biomol Chem. 2013 Sep 7;11(33):5500-11. doi: 10.1039/c3ob41074a.

PMID:
23860803
26.

Therapy response assessment in metastatic melanoma patients treated with a BRAF inhibitor: adapted Choi criteria can reflect early therapy response better than does RECIST.

Uhrig M, Hassel JC, Schlemmer HP, Ganten MK.

Acad Radiol. 2013 Apr;20(4):423-9. doi: 10.1016/j.acra.2012.09.029.

PMID:
23498982
27.

Escherichia coli β-galactosidase inhibitors through modifications at the aglyconic moiety: experimental evidence of conformational distortion in the molecular recognition process.

Calle L, Roldós V, Cañada FJ, Uhrig ML, Cagnoni AJ, Manzano VE, Varela O, Jiménez-Barbero J.

Chemistry. 2013 Mar 25;19(13):4262-70. doi: 10.1002/chem.201203673. Epub 2013 Feb 19.

PMID:
23424005
28.
29.

Synthesis of branched dithiotrisaccharides via ring-opening reaction of sugar thiiranes.

Repetto E, Manzano VE, Uhrig ML, Varela O.

J Org Chem. 2012 Jan 6;77(1):253-65. doi: 10.1021/jo2018685. Epub 2011 Nov 30.

PMID:
22092141
30.

Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight.

Amtul Z, Uhrig M, Wang L, Rozmahel RF, Beyreuther K.

Neurobiol Aging. 2012 Apr;33(4):831.e21-31. doi: 10.1016/j.neurobiolaging.2011.07.014. Epub 2011 Sep 13. Erratum in: Neurobiol Aging. 2018 Feb;62:247.

PMID:
21920632
31.

Additive effects of fatty acid mixtures on the levels and ratio of amyloid β40/42 peptides differ from the effects of individual fatty acids.

Amtul Z, Uhrig M, Beyreuther K.

J Neurosci Res. 2011 Nov;89(11):1795-801. doi: 10.1002/jnr.22706. Epub 2011 Jul 11.

PMID:
21748777
32.

Synthesis of multivalent glycoclusters from 1-thio-β-D-galactose and their inhibitory activity against the β-galactosidase from E. coli.

Cagnoni AJ, Varela O, Gouin SG, Kovensky J, Uhrig ML.

J Org Chem. 2011 May 6;76(9):3064-77. doi: 10.1021/jo102421e. Epub 2011 Apr 8.

PMID:
21446743
33.

Structural insight into the differential effects of omega-3 and omega-6 fatty acids on the production of Abeta peptides and amyloid plaques.

Amtul Z, Uhrig M, Rozmahel RF, Beyreuther K.

J Biol Chem. 2011 Feb 25;286(8):6100-7. doi: 10.1074/jbc.M110.183608. Epub 2010 Oct 22.

34.

Phospholipids and a phospholipid-rich diet alter the in vitro amyloid-beta peptide levels and amyloid-beta 42/40 ratios.

Amtul Z, Uhrig M, Supino R, Beyreuther K.

Neurosci Lett. 2010 Sep 6;481(2):73-7. doi: 10.1016/j.neulet.2010.06.046. Epub 2010 Jun 19.

PMID:
20600609
35.

New Alzheimer amyloid beta responsive genes identified in human neuroblastoma cells by hierarchical clustering.

Uhrig M, Ittrich C, Wiedmann V, Knyazev Y, Weninger A, Riemenschneider M, Hartmann T.

PLoS One. 2009 Aug 26;4(8):e6779. doi: 10.1371/journal.pone.0006779.

36.

Synthesis of pentopyranosyl-containing thiodisaccharides. Inhibitory activity against beta-glycosidases.

Cagnoni AJ, Uhrig ML, Varela O.

Bioorg Med Chem. 2009 Sep 1;17(17):6203-12. doi: 10.1016/j.bmc.2009.07.055. Epub 2009 Jul 26.

PMID:
19674908
37.

Thiodisaccharides with galactofuranose or arabinofuranose as terminal units: synthesis and inhibitory activity of an exo beta-D-galactofuranosidase.

Repetto E, Marino C, Uhrig ML, Varela O.

Bioorg Med Chem. 2009 Apr 1;17(7):2703-11. doi: 10.1016/j.bmc.2009.02.045. Epub 2009 Feb 26.

PMID:
19282191
38.

Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Abeta42 reduces their differentiation potential.

Uhrig M, Brechlin P, Jahn O, Knyazev Y, Weninger A, Busia L, Honarnejad K, Otto M, Hartmann T.

BMC Med. 2008 Dec 16;6:38. doi: 10.1186/1741-7015-6-38.

39.

Straightforward synthesis of thiodisaccharides by ring-opening of sugar epoxides.

Manzano VE, Uhrig ML, Varela O.

J Org Chem. 2008 Sep 19;73(18):7224-35. doi: 10.1021/jo8012397. Epub 2008 Aug 22.

PMID:
18717587
40.

Primitive and committed human hematopoietic progenitor cells interact with primary murine neural cells and are induced to undergo self-renewing cell divisions.

Gottschling S, Eckstein V, Saffrich R, Jonás A, Uhrig M, Krause U, Seckinger A, Miesala K, Horsch K, Straub BK, Ho AD.

Exp Hematol. 2007 Dec;35(12):1858-71. Epub 2007 Aug 13.

PMID:
17697743
41.

Synthesis of non-glycosidic 4,6'-thioether-linked disaccharides as hydrolytically stable glycomimetics.

Uhrig ML, Szilágyi L, Kövér KE, Varela O.

Carbohydr Res. 2007 Sep 3;342(12-13):1841-9. Epub 2007 Apr 2.

PMID:
17466289
42.

Glycosphingolipids in Plasmodium falciparum. Presence of an active glucosylceramide synthase.

Couto AS, Caffaro C, Uhrig ML, Kimura E, Peres VJ, Merino EF, Katzin AM, Nishioka M, Nonami H, Erra-Balsells R.

Eur J Biochem. 2004 Jun;271(11):2204-14.

43.

Two domains of the progesterone receptor interact with the estrogen receptor and are required for progesterone activation of the c-Src/Erk pathway in mammalian cells.

Ballaré C, Uhrig M, Bechtold T, Sancho E, Di Domenico M, Migliaccio A, Auricchio F, Beato M.

Mol Cell Biol. 2003 Mar;23(6):1994-2008.

44.
45.

Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum.

de Macedo CS, Uhrig ML, Kimura EA, Katzin AM.

FEMS Microbiol Lett. 2002 Jan 22;207(1):13-20.

46.

Limonene arrests parasite development and inhibits isoprenylation of proteins in Plasmodium falciparum.

Moura IC, Wunderlich G, Uhrig ML, Couto AS, Peres VJ, Katzin AM, Kimura EA.

Antimicrob Agents Chemother. 2001 Sep;45(9):2553-8.

47.
48.

Chemical and biological studies of a new cigarette that primarily heats tobacco. Part 1. Chemical composition of mainstream smoke.

Borgerding MF, Bodnar JA, Chung HL, Mangan PP, Morrison CC, Risner CH, Rogers JC, Simmons DF, Uhrig MS, Wendelboe FN, Wingate DE, Winkler LS.

Food Chem Toxicol. 1998 Jul;36(7):169-82.

PMID:
9687969
49.

Chemical and biological studies of a new cigarette that primarily heats tobacco. Part 1. Chemical composition of mainstream smoke.

Borgerding MF, Bodnar JA, Chung HL, Mangan PP, Morrison CC, Risner CH, Rogers JC, Simmons DF, Uhrig MS, Wendelboe FN, Wingate DE, Winkler LS.

Food Chem Toxicol. 1998 Mar;36(3):169-82. Corrected and republished in: Food Chem Toxicol. 1998 Jul;36(7):169-82.

PMID:
9609390
50.

Trypanosoma cruzi: nitrogenous-base-containing phosphatides in trypomastigote forms--isolation and chemical analysis.

Uhrig ML, Couto AS, Alves MJ, Colli W, de Lederkremer RM.

Exp Parasitol. 1997 Sep;87(1):8-19.

PMID:
9287953

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