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Items: 1 to 50 of 67

1.

Rapid Generation of Human Genetic Loss-of-Function iPSC Lines by Simultaneous Reprogramming and Gene Editing.

Tidball AM, Dang LT, Glenn TW, Kilbane EG, Klarr DJ, Margolis JL, Uhler MD, Parent JM.

Stem Cell Reports. 2017 Sep 12;9(3):725-731. doi: 10.1016/j.stemcr.2017.07.003. Epub 2017 Aug 3.

2.

HIF2α Is an Essential Molecular Brake for Postprandial Hepatic Glucagon Response Independent of Insulin Signaling.

Ramakrishnan SK, Zhang H, Takahashi S, Centofanti B, Periyasamy S, Weisz K, Chen Z, Uhler MD, Rui L, Gonzalez FJ, Shah YM.

Cell Metab. 2016 Mar 8;23(3):505-16. doi: 10.1016/j.cmet.2016.01.004. Epub 2016 Feb 4.

3.

Transcriptional regulatory events initiated by Ascl1 and Neurog2 during neuronal differentiation of P19 embryonic carcinoma cells.

Huang HS, Redmond TM, Kubish GM, Gupta S, Thompson RC, Turner DL, Uhler MD.

J Mol Neurosci. 2015 Mar;55(3):684-705. doi: 10.1007/s12031-014-0408-2. Epub 2014 Sep 6.

PMID:
25189318
4.

Negative regulation of Yap during neuronal differentiation.

Zhang H, Deo M, Thompson RC, Uhler MD, Turner DL.

Dev Biol. 2012 Jan 1;361(1):103-15. doi: 10.1016/j.ydbio.2011.10.017. Epub 2011 Oct 18.

5.

Ascl1-induced neuronal differentiation of P19 cells requires expression of a specific inhibitor protein of cyclic AMP-dependent protein kinase.

Huang HS, Turner DL, Thompson RC, Uhler MD.

J Neurochem. 2012 Mar;120(5):667-83. doi: 10.1111/j.1471-4159.2011.07332.x. Epub 2011 Jun 24.

6.

A novel fluorescent transcriptional reporter for cell-based microarray assays.

Redmond TM, Uhler MD.

Methods Mol Biol. 2011;706:41-52. doi: 10.1007/978-1-61737-970-3_4.

PMID:
21104053
7.

Direct transcriptional induction of Gadd45gamma by Ascl1 during neuronal differentiation.

Huang HS, Kubish GM, Redmond TM, Turner DL, Thompson RC, Murphy GG, Uhler MD.

Mol Cell Neurosci. 2010 Jul;44(3):282-96. doi: 10.1016/j.mcn.2010.03.014. Epub 2010 Apr 9.

8.

Microarray transfection analysis of conserved genomic sequences from three immediate early genes.

Ren X, Uhler MD.

Genomics. 2009 Feb;93(2):159-68. doi: 10.1016/j.ygeno.2008.09.017. Epub 2008 Nov 8.

9.

Implications of a simple mathematical model to cancer cell population dynamics.

Garner AL, Lau YY, Jordan DW, Uhler MD, Gilgenbach RM.

Cell Prolif. 2006 Feb;39(1):15-28.

PMID:
16426419
10.

Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons.

Leinninger GM, Backus C, Uhler MD, Lentz SI, Feldman EL.

FASEB J. 2004 Oct;18(13):1544-6. Epub 2004 Aug 19.

PMID:
15319368
11.

Microarray transfection analysis of transcriptional regulation by cAMP-dependent protein kinase.

Redmond TM, Ren X, Kubish G, Atkins S, Low S, Uhler MD.

Mol Cell Proteomics. 2004 Aug;3(8):770-9. Epub 2004 Apr 26.

12.

A transforming growth factor beta-induced Smad3/Smad4 complex directly activates protein kinase A.

Zhang L, Duan CJ, Binkley C, Li G, Uhler MD, Logsdon CD, Simeone DM.

Mol Cell Biol. 2004 Mar;24(5):2169-80.

13.

Autoinhibition and isoform-specific dominant negative inhibition of the type II cGMP-dependent protein kinase.

Taylor MK, Ahmed R, Begley M, Uhler MD.

J Biol Chem. 2002 Oct 4;277(40):37242-53. Epub 2002 Jul 1.

14.

Vascular endothelial cells express isoforms of protein kinase A inhibitor.

Lum H, Hao Z, Gayle D, Kumar P, Patterson CE, Uhler MD.

Am J Physiol Cell Physiol. 2002 Jan;282(1):C59-66.

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A cGMP-dependent protein kinase is implicated in wild-type motility in C. elegans.

Stansberry J, Baude EJ, Taylor MK, Chen PJ, Jin SW, Ellis RE, Uhler MD.

J Neurochem. 2001 Feb;76(4):1177-87.

17.

Localization of cGMP-dependent protein kinase isoforms in mouse eye.

Gamm DM, Barthel LK, Raymond PA, Uhler MD.

Invest Ophthalmol Vis Sci. 2000 Aug;41(9):2766-73.

PMID:
10937596
19.

Molecular cloning and expression of mammalian peroxisomal trans-2-enoyl-coenzyme A reductase cDNAs.

Das AK, Uhler MD, Hajra AK.

J Biol Chem. 2000 Aug 11;275(32):24333-40.

20.

Deficient gene expression in protein kinase inhibitor alpha Null mutant mice.

Gangolli EA, Belyamani M, Muchinsky S, Narula A, Burton KA, McKnight GS, Uhler MD, Idzerda RL.

Mol Cell Biol. 2000 May;20(10):3442-8.

22.

Cloning and characterization of zRICH, a 2',3'-cyclic-nucleotide 3'-phosphodiesterase induced during zebrafish optic nerve regeneration.

Ballestero RP, Dybowski JA, Levy G, Agranoff BW, Uhler MD.

J Neurochem. 1999 Apr;72(4):1362-71.

24.

Phosphorylation-dependent inhibition of protein phosphatase-1 by G-substrate. A Purkinje cell substrate of the cyclic GMP-dependent protein kinase.

Hall KU, Collins SP, Gamm DM, Massa E, DePaoli-Roach AA, Uhler MD.

J Biol Chem. 1999 Feb 5;274(6):3485-95.

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gRICH68 and gRICH70 are 2',3'-cyclic-nucleotide 3'-phosphodiesterases induced during goldfish optic nerve regeneration.

Ballestero RP, Wilmot GR, Agranoff BW, Uhler MD.

J Biol Chem. 1997 Apr 25;272(17):11479-86.

27.

The mouse Prkacn2 gene encoding protein kinase A inhibitor 2 is located on proximal chromosome 10.

Scarpetta MA, Uhler MD, Meisler MH.

Mamm Genome. 1996 Dec;7(12):921-2. No abstract available.

PMID:
8995769
28.

Cloning of CDP-diacylglycerol synthase from a human neuronal cell line.

Heacock AM, Uhler MD, Agranoff BW.

J Neurochem. 1996 Nov;67(5):2200-3.

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Molecular cloning and expression of cDNA encoding rat brain cytosolic acyl-coenzyme A thioester hydrolase.

Broustas CG, Larkins LK, Uhler MD, Hajra AK.

J Biol Chem. 1996 May 3;271(18):10470-6.

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Differential expression of mRNAs for protein kinase inhibitor isoforms in mouse brain.

Seasholtz AF, Gamm DM, Ballestero RP, Scarpetta MA, Uhler MD.

Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1734-8.

36.

Investigation by transient transfection of the effects on regulated exocytosis of Rab3a.

Holz RW, Senter RA, Uhler MD.

Methods Enzymol. 1995;257:221-31. No abstract available.

PMID:
8583925
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Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase.

Wang X, Uhler MD, Billestrup N, Norstedt G, Talamantes F, Nielsen JH, Carter-Su C.

J Biol Chem. 1992 Aug 25;267(24):17390-6.

47.

Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element.

Karpinski BA, Morle GD, Huggenvik J, Uhler MD, Leiden JM.

Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):4820-4.

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Regulation of the human enkephalin promoter by two isoforms of the catalytic subunit of cyclic adenosine 3',5'-monophosphate-dependent protein kinase.

Huggenvik JI, Collard MW, Stofko RE, Seasholtz AF, Uhler MD.

Mol Endocrinol. 1991 Jul;5(7):921-30.

PMID:
1658633

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