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Items: 1 to 50 of 68

1.

Improved Pathological Examination of Tumors with 3D Light-Sheet Microscopy.

Uhlén P, Tanaka N.

Trends Cancer. 2018 May;4(5):337-341. doi: 10.1016/j.trecan.2018.03.003. Epub 2018 Mar 27.

PMID:
29709257
2.

Glycosylation controls sodium-calcium exchanger 3 sub-cellular localization during cell cycle.

Liu T, Zhao J, Ibarra C, Garcia MU, Uhlén P, Nistér M.

Eur J Cell Biol. 2018 Apr;97(3):190-203. doi: 10.1016/j.ejcb.2018.02.004. Epub 2018 Feb 28.

3.

Mapping of the three-dimensional lymphatic microvasculature in bladder tumours using light-sheet microscopy.

Tanaka N, Kaczynska D, Kanatani S, Sahlgren C, Mitura P, Stepulak A, Miyakawa A, Wiklund P, Uhlén P.

Br J Cancer. 2018 Apr;118(7):995-999. doi: 10.1038/s41416-018-0016-y. Epub 2018 Mar 8.

4.

Voltage-dependent calcium channel signaling mediates GABAA receptor-induced migratory activation of dendritic cells infected by Toxoplasma gondii.

Kanatani S, Fuks JM, Olafsson EB, Westermark L, Chambers B, Varas-Godoy M, Uhlén P, Barragan A.

PLoS Pathog. 2017 Dec 7;13(12):e1006739. doi: 10.1371/journal.ppat.1006739. eCollection 2017 Dec.

5.

Regulation of radial glial process growth by glutamate via mGluR5/TRPC3 and neuregulin/ErbB4.

Louhivuori LM, Turunen PM, Louhivuori V, Yellapragada V, Nordström T, Uhlén P, Åkerman KE.

Glia. 2018 Jan;66(1):94-107. doi: 10.1002/glia.23230. Epub 2017 Sep 9.

PMID:
28887860
6.

An ex vivo spinal cord injury model to study ependymal cells in adult mouse tissue.

Fernandez-Zafra T, Codeluppi S, Uhlén P.

Exp Cell Res. 2017 Aug 15;357(2):236-242. doi: 10.1016/j.yexcr.2017.06.002. Epub 2017 Jun 3.

PMID:
28587745
7.

Mapping genes for calcium signaling and their associated human genetic disorders.

Hörtenhuber M, Toledo EM, Smedler E, Arenas E, Malmersjö S, Louhivuori L, Uhlén P.

Bioinformatics. 2017 Aug 15;33(16):2547-2554. doi: 10.1093/bioinformatics/btx225.

8.

Expression of Pluripotency Markers in Nonpluripotent Human Neural Stem and Progenitor Cells.

Vincent PH, Benedikz E, Uhlén P, Hovatta O, Sundström E.

Stem Cells Dev. 2017 Jun 15;26(12):876-887. doi: 10.1089/scd.2016.0346. Epub 2017 Mar 27.

PMID:
28351210
9.

Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses.

Niklasson M, Maddalo G, Sramkova Z, Mutlu E, Wee S, Sekyrova P, Schmidt L, Fritz N, Dehnisch I, Kyriatzis G, Krafcikova M, Carson BB, Feenstra JM, Marinescu VD, Segerman A, Haraldsson M, Gustavsson AL, Hammarström LG, Jenmalm Jensen A, Uhrbom L, Altelaar AF, Linnarsson S, Uhlén P, Trantirek L, Vincent CT, Nelander S, Enger PØ, Andäng M.

Cancer Res. 2017 Apr 1;77(7):1741-1752. doi: 10.1158/0008-5472.CAN-16-2274. Epub 2017 Jan 13.

10.

Acquired platinum resistance involves epithelial to mesenchymal transition through ubiquitin ligase FBXO32 dysregulation.

Tanaka N, Kosaka T, Miyazaki Y, Mikami S, Niwa N, Otsuka Y, Minamishima YA, Mizuno R, Kikuchi E, Miyajima A, Sabe H, Okada Y, Uhlén P, Suematsu M, Oya M.

JCI Insight. 2016 Nov 3;1(18):e83654.

11.

CO2-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture.

Forsberg D, Horn Z, Tserga E, Smedler E, Silberberg G, Shvarev Y, Kaila K, Uhlén P, Herlenius E.

Elife. 2016 Jul 5;5. pii: e14170. doi: 10.7554/eLife.14170.

12.

Wnt/β-Catenin Stimulation and Laminins Support Cardiovascular Cell Progenitor Expansion from Human Fetal Cardiac Mesenchymal Stromal Cells.

Månsson-Broberg A, Rodin S, Bulatovic I, Ibarra C, Löfling M, Genead R, Wärdell E, Felldin U, Granath C, Alici E, Le Blanc K, Smith CIE, Salašová A, Westgren M, Sundström E, Uhlén P, Arenas E, Sylvén C, Tryggvason K, Corbascio M, Simonson OE, Österholm C, Grinnemo KH.

Stem Cell Reports. 2016 Apr 12;6(4):607-617. doi: 10.1016/j.stemcr.2016.02.014. Epub 2016 Mar 24.

13.

The 1p36 Tumor Suppressor KIF 1Bβ Is Required for Calcineurin Activation, Controlling Mitochondrial Fission and Apoptosis.

Li S, Fell SM, Surova O, Smedler E, Wallis K, Chen ZX, Hellman U, Johnsen JI, Martinsson T, Kenchappa RS, Uhlén P, Kogner P, Schlisio S.

Dev Cell. 2016 Jan 25;36(2):164-78. doi: 10.1016/j.devcel.2015.12.029.

14.

Infection by Toxoplasma gondii Induces Amoeboid-Like Migration of Dendritic Cells in a Three-Dimensional Collagen Matrix.

Kanatani S, Uhlén P, Barragan A.

PLoS One. 2015 Sep 25;10(9):e0139104. doi: 10.1371/journal.pone.0139104. eCollection 2015.

15.

The COUP-TFII/Neuropilin-2 is a molecular switch steering diencephalon-derived GABAergic neurons in the developing mouse brain.

Kanatani S, Honda T, Aramaki M, Hayashi K, Kubo K, Ishida M, Tanaka DH, Kawauchi T, Sekine K, Kusuzawa S, Kawasaki T, Hirata T, Tabata H, Uhlén P, Nakajima K.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):E4985-94. doi: 10.1073/pnas.1420701112. Epub 2015 Aug 24.

16.

Sublethal caspase activation promotes generation of cardiomyocytes from embryonic stem cells.

Bulatovic I, Ibarra C, Österholm C, Wang H, Beltrán-Rodríguez A, Varas-Godoy M, Månsson-Broberg A, Uhlén P, Simon A, Grinnemo KH.

PLoS One. 2015 Mar 12;10(3):e0120176. doi: 10.1371/journal.pone.0120176. eCollection 2015.

17.

Calcium signaling in neocortical development.

Uhlén P, Fritz N, Smedler E, Malmersjö S, Kanatani S.

Dev Neurobiol. 2015 Apr;75(4):360-8. doi: 10.1002/dneu.22273. Epub 2015 Feb 18. Review.

18.

Network analysis of time-lapse microscopy recordings.

Smedler E, Malmersjö S, Uhlén P.

Front Neural Circuits. 2014 Sep 17;8:111. doi: 10.3389/fncir.2014.00111. eCollection 2014.

19.

Tracheal tissue engineering in rats.

Jungebluth P, Haag JC, Sjöqvist S, Gustafsson Y, Beltrán Rodríguez A, Del Gaudio C, Bianco A, Dehnisch I, Uhlén P, Baiguera S, Lemon G, Lim ML, Macchiarini P.

Nat Protoc. 2014 Sep;9(9):2164-79. doi: 10.1038/nprot.2014.149. Epub 2014 Aug 14.

PMID:
25122525
20.

AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion.

Mojallal M, Zheng Y, Hultin S, Audebert S, van Harn T, Johnsson P, Lenander C, Fritz N, Mieth C, Corcoran M, Lembo F, Hallström M, Hartman J, Mazure NM, Weide T, Grandér D, Borg JP, Uhlén P, Holmgren L.

Nat Commun. 2014 Aug 1;5:4557. doi: 10.1038/ncomms5557.

PMID:
25080976
21.

An integrated mechanism of cardiomyocyte nuclear Ca(2+) signaling.

Ibarra C, Vicencio JM, Varas-Godoy M, Jaimovich E, Rothermel BA, Uhlén P, Hill JA, Lavandero S.

J Mol Cell Cardiol. 2014 Oct;75:40-8. doi: 10.1016/j.yjmcc.2014.06.015. Epub 2014 Jul 2. Review.

22.

AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion.

Hultin S, Zheng Y, Mojallal M, Vertuani S, Gentili C, Balland M, Milloud R, Belting HG, Affolter M, Helker CS, Adams RH, Herzog W, Uhlen P, Majumdar A, Holmgren L.

Nat Commun. 2014 May 7;5:3743. doi: 10.1038/ncomms4743.

PMID:
24806444
23.

Cathelicidin LL-37 induces time-resolved release of LTB4 and TXA2 by human macrophages and triggers eicosanoid generation in vivo.

Wan M, Soehnlein O, Tang X, van der Does AM, Smedler E, Uhlén P, Lindbom L, Agerberth B, Haeggström JZ.

FASEB J. 2014 Aug;28(8):3456-67. doi: 10.1096/fj.14-251306. Epub 2014 Apr 15.

PMID:
24736410
24.

Interleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signaling.

Codeluppi S, Fernandez-Zafra T, Sandor K, Kjell J, Liu Q, Abrams M, Olson L, Gray NS, Svensson CI, Uhlén P.

PLoS One. 2014 Mar 25;9(3):e92649. doi: 10.1371/journal.pone.0092649. eCollection 2014.

25.

MYC proteins promote neuronal differentiation by controlling the mode of progenitor cell division.

Zinin N, Adameyko I, Wilhelm M, Fritz N, Uhlén P, Ernfors P, Henriksson MA.

EMBO Rep. 2014 Apr;15(4):383-91. doi: 10.1002/embr.201337424. Epub 2014 Mar 5.

26.

Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1.

Bräutigam L, Jensen LD, Poschmann G, Nyström S, Bannenberg S, Dreij K, Lepka K, Prozorovski T, Montano SJ, Aktas O, Uhlén P, Stühler K, Cao Y, Holmgren A, Berndt C.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20057-62. doi: 10.1073/pnas.1313753110. Epub 2013 Nov 25.

27.

Frequency decoding of calcium oscillations.

Smedler E, Uhlén P.

Biochim Biophys Acta. 2014 Mar;1840(3):964-9. doi: 10.1016/j.bbagen.2013.11.015. Epub 2013 Nov 22. Review.

28.

Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons.

Yang S, Edman LC, Sánchez-Alcañiz JA, Fritz N, Bonilla S, Hecht J, Uhlén P, Pleasure SJ, Villaescusa JC, Marín O, Arenas E.

Development. 2013 Nov;140(22):4554-64. doi: 10.1242/dev.098145. Epub 2013 Oct 23.

29.

Small-world networks of spontaneous Ca(2+) activity.

Malmersjö S, Rebellato P, Smedler E, Uhlén P.

Commun Integr Biol. 2013 Jul 1;6(4):e24788. doi: 10.4161/cib.24788. Epub 2013 May 10.

30.

Reply: Comment on 'Quiescence and yH2AX in neuroblastoma are regulated by ouabain/Na,K-ATPase': ouabain and cancer.

Hiyoshi H, Johnsen JI, Andäng M, Uhlén P.

Br J Cancer. 2013 May 28;108(10):2191. doi: 10.1038/bjc.2013.235. Epub 2013 May 16. No abstract available.

31.

Neural progenitors organize in small-world networks to promote cell proliferation.

Malmersjö S, Rebellato P, Smedler E, Planert H, Kanatani S, Liste I, Nanou E, Sunner H, Abdelhady S, Zhang S, Andäng M, El Manira A, Silberberg G, Arenas E, Uhlén P.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):E1524-32. doi: 10.1073/pnas.1220179110. Epub 2013 Apr 1.

32.

Perfluorooctane sulfonate induces neuronal and oligodendrocytic differentiation in neural stem cells and alters the expression of PPARγ in vitro and in vivo.

Wan Ibrahim WN, Tofighi R, Onishchenko N, Rebellato P, Bose R, Uhlén P, Ceccatelli S.

Toxicol Appl Pharmacol. 2013 May 15;269(1):51-60. doi: 10.1016/j.taap.2013.03.003. Epub 2013 Mar 14.

PMID:
23500012
33.

Intracellular calcium release modulates polycystin-2 trafficking.

Miyakawa A, Ibarra C, Malmersjö S, Aperia A, Wiklund P, Uhlén P.

BMC Nephrol. 2013 Feb 11;14:34. doi: 10.1186/1471-2369-14-34.

34.

Local control of nuclear calcium signaling in cardiac myocytes by perinuclear microdomains of sarcolemmal insulin-like growth factor 1 receptors.

Ibarra C, Vicencio JM, Estrada M, Lin Y, Rocco P, Rebellato P, Munoz JP, Garcia-Prieto J, Quest AF, Chiong M, Davidson SM, Bulatovic I, Grinnemo KH, Larsson O, Szabadkai G, Uhlén P, Jaimovich E, Lavandero S.

Circ Res. 2013 Jan 18;112(2):236-45. doi: 10.1161/CIRCRESAHA.112.273839. Epub 2012 Nov 1.

PMID:
23118311
35.

The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2.

Gaengel K, Niaudet C, Hagikura K, Laviña B, Muhl L, Hofmann JJ, Ebarasi L, Nyström S, Rymo S, Chen LL, Pang MF, Jin Y, Raschperger E, Roswall P, Schulte D, Benedito R, Larsson J, Hellström M, Fuxe J, Uhlén P, Adams R, Jakobsson L, Majumdar A, Vestweber D, Uv A, Betsholtz C.

Dev Cell. 2012 Sep 11;23(3):587-99. doi: 10.1016/j.devcel.2012.08.005. Erratum in: Dev Cell. 2012 Dec 11;23(6):1264. Laviña Siemsen, Bàrbara [corrected to Laviña, Bàrbara].

36.

Quiescence and γH2AX in neuroblastoma are regulated by ouabain/Na,K-ATPase.

Hiyoshi H, Abdelhady S, Segerström L, Sveinbjörnsson B, Nuriya M, Lundgren TK, Desfrere L, Miyakawa A, Yasui M, Kogner P, Johnsen JI, Andäng M, Uhlén P.

Br J Cancer. 2012 May 22;106(11):1807-15. doi: 10.1038/bjc.2012.159. Epub 2012 Apr 24.

37.

Small molecule screening platform for assessment of cardiovascular toxicity on adult zebrafish heart.

Kitambi SS, Nilsson ES, Sekyrova P, Ibarra C, Tekeoh GN, Andäng M, Ernfors P, Uhlén P.

BMC Physiol. 2012 Mar 26;12:3. doi: 10.1186/1472-6793-12-3.

38.

Origin of excitation underlying locomotion in the spinal circuit of zebrafish.

Eklöf-Ljunggren E, Haupt S, Ausborn J, Dehnisch I, Uhlén P, Higashijima S, El Manira A.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5511-6. doi: 10.1073/pnas.1115377109. Epub 2012 Mar 19.

39.

RET PLCγ phosphotyrosine binding domain regulates Ca2+ signaling and neocortical neuronal migration.

Lundgren TK, Nakahata K, Fritz N, Rebellato P, Zhang S, Uhlén P.

PLoS One. 2012;7(2):e31258. doi: 10.1371/journal.pone.0031258. Epub 2012 Feb 15.

40.

PfMDR1: mechanisms of transport modulation by functional polymorphisms.

Ferreira PE, Holmgren G, Veiga MI, Uhlén P, Kaneko A, Gil JP.

PLoS One. 2011;6(9):e23875. doi: 10.1371/journal.pone.0023875. Epub 2011 Sep 1.

41.

Non-dioxin-like polychlorinated biphenyls interfere with neuronal differentiation of embryonic neural stem cells.

Tofighi R, Wan Ibrahim WN, Rebellato P, Andersson PL, Uhlén P, Ceccatelli S.

Toxicol Sci. 2011 Nov;124(1):192-201. doi: 10.1093/toxsci/kfr221. Epub 2011 Sep 9.

PMID:
21908764
42.

Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission.

Zhao J, Liu T, Jin S, Wang X, Qu M, Uhlén P, Tomilin N, Shupliakov O, Lendahl U, Nistér M.

EMBO J. 2011 Jun 24;30(14):2762-78. doi: 10.1038/emboj.2011.198.

43.

Inositol 1,4,5-trisphosphate receptor subtype-specific regulation of calcium oscillations.

Zhang S, Fritz N, Ibarra C, Uhlén P.

Neurochem Res. 2011 Jul;36(7):1175-85. doi: 10.1007/s11064-011-0457-7. Epub 2011 Apr 11. Review.

44.

Noggin and Wnt3a enable BMP4-dependent differentiation of telencephalic stem cells into GluR-agonist responsive neurons.

Andersson T, Duckworth JK, Fritz N, Lewicka M, Södersten E, Uhlén P, Hermanson O.

Mol Cell Neurosci. 2011 May;47(1):10-8. doi: 10.1016/j.mcn.2011.01.006. Epub 2011 Jan 14.

PMID:
21238590
45.

Calcium signaling in placenta.

Baczyk D, Kingdom JC, Uhlén P.

Cell Calcium. 2011 May;49(5):350-6. doi: 10.1016/j.ceca.2010.12.003. Epub 2011 Jan 14. Review.

PMID:
21236488
46.

Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis.

Norberg E, Karlsson M, Korenovska O, Szydlowski S, Silberberg G, Uhlén P, Orrenius S, Zhivotovsky B.

EMBO J. 2010 Nov 17;29(22):3869-78. doi: 10.1038/emboj.2010.253. Epub 2010 Oct 29.

47.

En masse in vitro functional profiling of the axonal mechanosensitivity of sensory neurons.

Usoskin D, Zilberter M, Linnarsson S, Hjerling-Leffler J, Uhlén P, Harkany T, Ernfors P.

Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16336-41. doi: 10.1073/pnas.0914705107. Epub 2010 Aug 24.

48.

Biochemistry of calcium oscillations.

Uhlén P, Fritz N.

Biochem Biophys Res Commun. 2010 May 21;396(1):28-32. doi: 10.1016/j.bbrc.2010.02.117. Review.

PMID:
20494106
49.

Ca2+ and cAMP signaling in human embryonic stem cell-derived dopamine neurons.

Malmersjö S, Liste I, Dyachok O, Tengholm A, Arenas E, Uhlén P.

Stem Cells Dev. 2010 Sep;19(9):1355-64. doi: 10.1089/scd.2009.0436.

PMID:
20043754
50.

Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis.

Zheng Y, Vertuani S, Nyström S, Audebert S, Meijer I, Tegnebratt T, Borg JP, Uhlén P, Majumdar A, Holmgren L.

Circ Res. 2009 Jul 31;105(3):260-70. doi: 10.1161/CIRCRESAHA.109.195156. Epub 2009 Jul 9.

PMID:
19590046

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