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Items: 1 to 50 of 61

1.

A new, simple and robust radioligand binding method used to determine kinetic off-rate constants for unlabeled ligands. Application at α2A- and α2C-adrenoceptors.

Uhlén S, Schiöth HB, Jahnsen JA.

Eur J Pharmacol. 2016 Oct 5;788:113-121. doi: 10.1016/j.ejphar.2016.06.021. Epub 2016 Jun 16.

2.

Perspective on the role of the N-terminal tail of the α2C-adrenoceptor.

Uhlen S, Jahnsen JA.

Naunyn Schmiedebergs Arch Pharmacol. 2014 Oct;387(10):1013-4. doi: 10.1007/s00210-014-1029-6. Epub 2014 Aug 12. No abstract available.

PMID:
25110140
3.

The C-terminal half of the α2C-adrenoceptor determines the receptor's membrane expression level and drug selectivity.

Jahnsen JA, Uhlén S.

Naunyn Schmiedebergs Arch Pharmacol. 2013 Dec;386(12):1031-40. doi: 10.1007/s00210-013-0902-z. Epub 2013 Jul 20.

PMID:
23868076
4.

The predicted N-terminal signal sequence of the human α₂C-adrenoceptor does not act as a functional cleavable signal peptide.

Jahnsen JA, Uhlén S.

Eur J Pharmacol. 2012 Jun 5;684(1-3):51-8. doi: 10.1016/j.ejphar.2012.03.044. Epub 2012 Apr 3.

PMID:
22503931
5.

The N-terminal region of the human 5-HT₂C receptor has as a cleavable signal peptide.

Jahnsen JA, Uhlén S.

Eur J Pharmacol. 2012 Jun 5;684(1-3):44-50. doi: 10.1016/j.ejphar.2012.03.043. Epub 2012 Apr 3.

PMID:
22497996
6.

Measurement of cement thickness under lithium disilicate crowns using an impression material technique.

Reich S, Uhlen S, Gozdowski S, Lohbauer U.

Clin Oral Investig. 2011 Aug;15(4):521-6. doi: 10.1007/s00784-010-0414-x. Epub 2010 May 12.

PMID:
20461424
7.

Effect of ursodeoxycholic acid on liver function in children after successful surgery for biliary atresia.

Willot S, Uhlen S, Michaud L, Briand G, Bonnevalle M, Sfeir R, Gottrand F.

Pediatrics. 2008 Dec;122(6):e1236-41. doi: 10.1542/peds.2008-0986. Epub 2008 Nov 24.

PMID:
19029197
8.

[D-lactic acidosis in a child with short bowel syndrome].

Dahhak S, Uhlen S, Mention K, Romond MB, Fontaine M, Gottrand F, Turck D, Michaud L.

Arch Pediatr. 2008 Feb;15(2):145-8. doi: 10.1016/j.arcped.2007.11.009. Epub 2008 Feb 1. French.

PMID:
18242965
9.

Proteochemometric analysis of small cyclic peptides' interaction with wild-type and chimeric melanocortin receptors.

Kontijevskis A, Petrovska R, Mutule I, Uhlen S, Komorowski J, Prusis P, Wikberg JE.

Proteins. 2007 Oct 1;69(1):83-96.

PMID:
17557335
10.

Proteochemometric modeling reveals the interaction site for Trp9 modified alpha-MSH peptides in melanocortin receptors.

Lapinsh M, Prusis P, Petrovska R, Uhlén S, Mutule I, Veiksina S, Wikberg JE.

Proteins. 2007 May 15;67(3):653-60.

PMID:
17357163
11.

[A rare cause of meconial ileus and intestinal perforation in a neonate].

Boman F, Sfeir R, Morineau M, Uhlen S, Gottrand F, Jaubert F.

Ann Pathol. 2006 Jun;26(3):220-2. French. No abstract available.

PMID:
17127856
12.

Efficacy of methotrexate in pediatric Crohn's disease: a French multicenter study.

Uhlen S, Belbouab R, Narebski K, Goulet O, Schmitz J, Cézard JP, Turck D, Ruemmele FM.

Inflamm Bowel Dis. 2006 Nov;12(11):1053-7.

PMID:
17075346
13.

Dramatic changes in home-based enteral nutrition practices in children during an 11-year period.

Daveluy W, Guimber D, Uhlen S, Lescut D, Michaud L, Turck D, Gottrand F.

J Pediatr Gastroenterol Nutr. 2006 Aug;43(2):240-4.

PMID:
16877992
14.

Mitomycin C: an alternative conservative treatment for refractory esophageal stricture in children?

Uhlen S, Fayoux P, Vachin F, Guimber D, Gottrand F, Turck D, Michaud L.

Endoscopy. 2006 Apr;38(4):404-7. Epub 2006 Feb 3.

PMID:
16586239
15.

Prediction of indirect interactions in proteins.

Prusis P, Uhlén S, Petrovska R, Lapinsh M, Wikberg JE.

BMC Bioinformatics. 2006 Mar 22;7:167.

16.

Nandrolone treatment decreases the alpha1B-adrenoceptor mRNA level in rat kidney, but not the density of alpha1B-adrenoceptors in cultured MDCK-D1 kidney cells.

Lindblom J, Petrovska R, Hallberg M, Magnusson K, Nyberg F, Uhlén S.

Eur J Pharmacol. 2005 Dec 19;527(1-3):157-62. Epub 2005 Nov 23. Erratum in: Eur J Pharmacol. 2006 Mar 18;534(1-3):286.

PMID:
16309668
17.

Improved approach for proteochemometrics modeling: application to organic compound--amine G protein-coupled receptor interactions.

Lapinsh M, Prusis P, Uhlén S, Wikberg JE.

Bioinformatics. 2005 Dec 1;21(23):4289-96. Epub 2005 Oct 4.

PMID:
16204343
18.

Mitomycin C as an alternative to stent for conservative management of esophageal strictures in children.

Uhlen S, Fayoux P, Michaud L.

J Pediatr Gastroenterol Nutr. 2005 Feb;40(2):235-6. No abstract available.

PMID:
15699708
19.
20.

Proteochemometric mapping of the interaction of organic compounds with melanocortin receptor subtypes.

Lapinsh M, Veiksina S, Uhlén S, Petrovska R, Mutule I, Mutulis F, Yahorava S, Prusis P, Wikberg JE.

Mol Pharmacol. 2005 Jan;67(1):50-9. Epub 2004 Oct 6.

21.

[Treatment of acute diarrhea: prescription patterns by private practice pediatricians].

Uhlen S, Toursel F, Gottrand F; Association française de pédiatrie ambulatoire.

Arch Pediatr. 2004 Aug;11(8):903-7. French.

PMID:
15288079
22.

Investigations on the pharmacology of the cardioprotective guanidine ME10092.

Dambrova M, Liepinsh E, Kirjanova O, Petrovska R, Pugovich O, Baumane L, Uhlen S, Kalvinsh I, Oliver D, Wikberg JE.

J Cardiovasc Pharmacol. 2004 Aug;44(2):178-86.

PMID:
15243298
23.

The methylester of gamma-butyrobetaine, but not gamma-butyrobetaine itself, induces muscarinic receptor-dependent vasodilatation.

Dambrova M, Chlopicki S, Liepinsh E, Kirjanova O, Gorshkova O, Kozlovski VI, Uhlen S, Liepina I, Petrovska R, Kalvinsh I.

Naunyn Schmiedebergs Arch Pharmacol. 2004 May;369(5):533-9. Epub 2004 Apr 2.

PMID:
15060760
24.

Nandrolone treatment decreases the level of rat kidney alpha(1B)-adrenoceptors.

Uhlén S, Lindblom J, Kindlundh A, Mugisha P, Nyberg F.

Naunyn Schmiedebergs Arch Pharmacol. 2003 Aug;368(2):91-8. Epub 2003 Jul 12.

PMID:
12861436
25.

Reduced natriuretic response to acute sodium loading in COMT gene deleted mice.

Odlind C, Reenilä I, Männistö PT, Juvonen R, Uhlén S, Gogos JA, Karayiorgou M, Hansell P.

BMC Physiol. 2002 Aug 21;2:14.

26.

[Are pediatricians liberal in their drug prescribing?].

Toursel F, Uhlen S, Gottrand F.

Arch Pediatr. 2002 May;9 Suppl 2:193s. French. No abstract available.

PMID:
12108265
27.

Migration of percutaneous endoscopic gastrostomy tube in children.

Uhlen S, Mention K, Michaud L.

J Pediatr Gastroenterol Nutr. 2002 May;34(5):568-9; author reply 569. No abstract available.

PMID:
12050588
28.

Binding of [(3)H]prazosin to alpha(1A)- and alpha(1B)-adrenoceptors, and to a cimetidine-sensitive non-alpha(1) binding site in rat kidney membranes.

Mugisha P, Gründemann D, Schömig E, Uhlén S.

Naunyn Schmiedebergs Arch Pharmacol. 2002 May;365(5):335-40. Epub 2002 Apr 5.

PMID:
12012018
29.

Characterization of alpha(1)-adrenoceptor subtypes in the eye.

Wikberg-Matsson A, Uhlén S, Wikberg JE.

Exp Eye Res. 2000 Jan;70(1):51-60.

PMID:
10644420
30.

Specific binding of proinsulin C-peptide to human cell membranes.

Rigler R, Pramanik A, Jonasson P, Kratz G, Jansson OT, Nygren P, Stâhl S, Ekberg K, Johansson B, Uhlén S, Uhlén M, Jörnvall H, Wahren J.

Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13318-23.

31.

Characterization of guanoxabenz reducing activity in rat brain.

Dambrova M, Uhlén S, Wikberg JE.

Pharmacol Toxicol. 1998 Oct;83(4):158-63.

PMID:
9820876
32.

Conditions for biphasic competition curves in radioligand binding for ligands subjected to metabolic transformation.

Wikberg JE, Dambrova M, Uhlén S, Prusis P.

Biochem Pharmacol. 1998 Nov 1;56(9):1129-37.

PMID:
9802322
35.

Identification of an N-hydroxyguanidine reducing activity of xanthine oxidase.

Dambrova M, Uhlén S, Welch CJ, Wikberg JE.

Eur J Biochem. 1998 Oct 1;257(1):178-84.

36.

Characterization of alpha1-adrenoceptor subtypes in the pig.

Wikberg-Matsson A, Wikberg JE, Uhlén S.

Eur J Pharmacol. 1998 Apr 24;347(2-3):301-9.

PMID:
9653897
38.

[3H]RS79948-197 binding to human, rat, guinea pig and pig alpha2A-, alpha2B- and alpha2C-adrenoceptors. Comparison with MK912, RX821002, rauwolscine and yohimbine.

Uhlén S, Dambrova M, Näsman J, Schiöth HB, Gu Y, Wikberg-Matsson A, Wikberg JE.

Eur J Pharmacol. 1998 Feb 5;343(1):93-101.

PMID:
9551719
39.

Autoradiographic studies of central alpha 2A- and alpha 2C-adrenoceptors in the rat using [3H]MK912 and subtype-selective drugs.

Uhlén S, Lindblom J, Johnson A, Wikberg JE.

Brain Res. 1997 Oct 3;770(1-2):261-6.

PMID:
9372228
40.

Quantification of alpha2A and alpha2C adrenoceptors in the rat striatum and in different regions of the spinal cord.

Uhlén S, Lindblom J, Tiger G, Wikberg JE.

Acta Physiol Scand. 1997 Aug;160(4):407-12.

PMID:
9338523
41.

Characterization of adrenoceptor types and subtypes in American bullfrogs acclimated to warm or cold temperature.

Herman CA, Luczy G, Wikberg JE, Uhlén S.

Gen Comp Endocrinol. 1996 Nov;104(2):168-78.

PMID:
8930607
43.
44.
45.
46.

Detomidine binding to guinea pig liver imidazoline receptors (I-receptors) shows marked positive cooperativity.

Rangel N, Uhlén S, Wikberg JE.

Pharmacol Toxicol. 1993 Aug;73(2):86-90.

PMID:
8248011
47.

Evidence for the existence of two forms of alpha 2A-adrenoceptors in the rat.

Uhlén S, Xia Y, Chhajlani V, Lien EJ, Wikberg JE.

Naunyn Schmiedebergs Arch Pharmacol. 1993 Mar;347(3):280-8.

PMID:
8097566
48.

Further evidence for the existence of two forms of alpha 2B-adrenoceptors in rat.

Xia Y, Uhlén S, Chhajlani V, Lien EJ, Wikberg JE.

Pharmacol Toxicol. 1993 Jan;72(1):40-9.

PMID:
8095097
49.

[3H]-MK 912 binding delineates two alpha 2-adrenoceptor subtypes in rat CNS one of which is identical with the cloned pA2d alpha 2-adrenoceptor.

Uhlén S, Xia Y, Chhajlani V, Felder CC, Wikberg JE.

Br J Pharmacol. 1992 Aug;106(4):986-95. Erratum in: Br J Pharmacol 1993 Mar;108(3):852.

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