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Best matches for Uhlén M[au]:

Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. Fagerberg L et al. Mol Cell Proteomics. (2014)

The Human Cell Atlas. Regev A et al. Elife. (2017)

A subcellular map of the human proteome. Thul PJ et al. Science. (2017)

Search results

Items: 1 to 50 of 610

1.

Systematic Development of Sandwich Immunoassays for the Plasma Secretome.

Häussler RS, Bendes A, Iglesias M, Sanchez-Rivera L, Dodig-Crnković T, Byström S, Fredolini C, Birgersson E, Dale M, Edfors F, Fagerberg L, Rockberg J, Tegel H, Uhlén M, Qundos U, Schwenk JM.

Proteomics. 2019 Jul 6:e1900008. doi: 10.1002/pmic.201900008. [Epub ahead of print]

PMID:
31278833
2.

Single-cell RNA-seq variant analysis for exploration of genetic heterogeneity in cancer.

Fasterius E, Uhlén M, Al-Khalili Szigyarto C.

Sci Rep. 2019 Jul 2;9(1):9524. doi: 10.1038/s41598-019-45934-1.

3.

Multi-Omic Data Interpretation to Repurpose Subtype Specific Drug Candidates for Breast Cancer.

Turanli B, Karagoz K, Bidkhori G, Sinha R, Gatza ML, Uhlen M, Mardinoglu A, Arga KY.

Front Genet. 2019 May 7;10:420. doi: 10.3389/fgene.2019.00420. eCollection 2019.

4.

Screening a Resource of Recombinant Protein Fragments for Targeted Proteomics.

Edfors F, Forsström B, Vunk H, Kotol D, Fredolini C, Maddalo G, Svensson AS, Boström T, Tegel H, Nilsson P, Schwenk JM, Uhlen M.

J Proteome Res. 2019 Jul 5;18(7):2706-2718. doi: 10.1021/acs.jproteome.8b00924. Epub 2019 Jun 7.

PMID:
31094526
5.

Treatment decisions regarding caries and dental developmental defects in children - a questionnaire-based study among Norwegian dentists.

Uhlen MM, Valen H, Karlsen LS, Skaare AB, Bletsa A, Ansteinsson V, Mulic A.

BMC Oral Health. 2019 May 10;19(1):80. doi: 10.1186/s12903-019-0744-2.

6.

Fissure sealants or fluoride varnish? Routines and attitudes among dental health personnel in Norway.

Uhlen MM, Wang NJ, Skudutyte-Rysstad R.

Eur Arch Paediatr Dent. 2019 Apr 12. doi: 10.1007/s40368-019-00440-w. [Epub ahead of print]

PMID:
30980252
7.

Expression of PD-L1 and PD-1 in Chemoradiotherapy-Naïve Esophageal and Gastric Adenocarcinoma: Relationship With Mismatch Repair Status and Survival.

Svensson MC, Borg D, Zhang C, Hedner C, Nodin B, Uhlén M, Mardinoglu A, Leandersson K, Jirström K.

Front Oncol. 2019 Mar 13;9:136. doi: 10.3389/fonc.2019.00136. eCollection 2019.

8.

Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning.

Turanli B, Zhang C, Kim W, Benfeitas R, Uhlen M, Arga KY, Mardinoglu A.

EBioMedicine. 2019 Apr;42:386-396. doi: 10.1016/j.ebiom.2019.03.009. Epub 2019 Mar 21.

9.

Development of parallel reaction monitoring assays for cerebrospinal fluid proteins associated with Alzheimer's disease.

Andersson A, Remnestål J, Nellgård B, Vunk H, Kotol D, Edfors F, Uhlén M, Schwenk JM, Ilag LL, Zetterberg H, Blennow K, Månberg A, Nilsson P, Fredolini C.

Clin Chim Acta. 2019 Jul;494:79-93. doi: 10.1016/j.cca.2019.03.243. Epub 2019 Mar 9.

10.

A Systematic Investigation of the Malignant Functions and Diagnostic Potential of the Cancer Secretome.

Robinson JL, Feizi A, Uhlén M, Nielsen J.

Cell Rep. 2019 Mar 5;26(10):2622-2635.e5. doi: 10.1016/j.celrep.2019.02.025.

11.

Individual and stable autoantibody repertoires in healthy individuals.

Neiman M, Hellström C, Just D, Mattsson C, Fagerberg L, Schuppe-Koistinen I, Gummesson A, Bergström G, Kallioniemi O, Achour A, Sallinen R, Uhlén M, Nilsson P.

Autoimmunity. 2019 Feb;52(1):1-11. doi: 10.1080/08916934.2019.1581774. Epub 2019 Mar 5.

PMID:
30835561
12.

Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues.

Eraslan B, Wang D, Gusic M, Prokisch H, Hallström BM, Uhlén M, Asplund A, Pontén F, Wieland T, Hopf T, Hahne H, Kuster B, Gagneur J.

Mol Syst Biol. 2019 Feb 18;15(2):e8513. doi: 10.15252/msb.20188513.

13.

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues.

Wang D, Eraslan B, Wieland T, Hallström B, Hopf T, Zolg DP, Zecha J, Asplund A, Li LH, Meng C, Frejno M, Schmidt T, Schnatbaum K, Wilhelm M, Ponten F, Uhlen M, Gagneur J, Hahne H, Kuster B.

Mol Syst Biol. 2019 Feb 18;15(2):e8503. doi: 10.15252/msb.20188503.

14.

SAMURAI (Solid-phase Assisted Mutagenesis by Uracil Restriction for Accurate Integration) for antibody affinity maturation and paratope mapping.

Hu FJ, Lundqvist M, Uhlén M, Rockberg J.

Nucleic Acids Res. 2019 Apr 8;47(6):e34. doi: 10.1093/nar/gkz050.

15.

Discovery of KIRREL as a biomarker for prognostic stratification of patients with thin melanoma.

Lundgren S, Fagerström-Vahman H, Zhang C, Ben-Dror L, Mardinoglu A, Uhlen M, Nodin B, Jirström K.

Biomark Res. 2019 Jan 14;7:1. doi: 10.1186/s40364-018-0153-8. eCollection 2019.

16.

Chromophore pre-maturation for improved speed and sensitivity of split-GFP monitoring of protein secretion.

Lundqvist M, Thalén N, Volk AL, Hansen HG, von Otter E, Nygren PÅ, Uhlen M, Rockberg J.

Sci Rep. 2019 Jan 22;9(1):310. doi: 10.1038/s41598-018-36559-x.

17.

Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function.

Liu Z, Zhang C, Lee S, Kim W, Klevstig M, Harzandi AM, Sikanic N, Arif M, Ståhlman M, Nielsen J, Uhlen M, Boren J, Mardinoglu A.

Metab Eng. 2019 Mar;52:263-272. doi: 10.1016/j.ymben.2019.01.001. Epub 2019 Jan 4.

PMID:
30615941
18.

Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis.

Benfeitas R, Bidkhori G, Mukhopadhyay B, Klevstig M, Arif M, Zhang C, Lee S, Cinar R, Nielsen J, Uhlen M, Boren J, Kunos G, Mardinoglu A.

EBioMedicine. 2019 Feb;40:471-487. doi: 10.1016/j.ebiom.2018.12.057. Epub 2018 Dec 31.

19.

Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes.

Bidkhori G, Benfeitas R, Klevstig M, Zhang C, Nielsen J, Uhlen M, Boren J, Mardinoglu A.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11874-E11883. doi: 10.1073/pnas.1807305115. Epub 2018 Nov 27.

20.

Levels of human proteins in plasma associated with acute paediatric malaria.

Reuterswärd P, Bergström S, Orikiiriza J, Lindquist E, Bergström S, Andersson Svahn H, Ayoglu B, Uhlén M, Wahlgren M, Normark J, Ribacke U, Nilsson P.

Malar J. 2018 Nov 15;17(1):426. doi: 10.1186/s12936-018-2576-y.

21.

ESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based Modeling.

Zhang C, Bidkhori G, Benfeitas R, Lee S, Arif M, Uhlén M, Mardinoglu A.

Front Physiol. 2018 Sep 28;9:1355. doi: 10.3389/fphys.2018.01355. eCollection 2018.

22.

Growth of Cyanobacteria Is Constrained by the Abundance of Light and Carbon Assimilation Proteins.

Jahn M, Vialas V, Karlsen J, Maddalo G, Edfors F, Forsström B, Uhlén M, Käll L, Hudson EP.

Cell Rep. 2018 Oct 9;25(2):478-486.e8. doi: 10.1016/j.celrep.2018.09.040.

23.

Enhanced validation of antibodies for research applications.

Edfors F, Hober A, Linderbäck K, Maddalo G, Azimi A, Sivertsson Å, Tegel H, Hober S, Szigyarto CA, Fagerberg L, von Feilitzen K, Oksvold P, Lindskog C, Forsström B, Uhlen M.

Nat Commun. 2018 Oct 8;9(1):4130. doi: 10.1038/s41467-018-06642-y.

24.

A systems-approach reveals human nestin is an endothelial-enriched, angiogenesis-independent intermediate filament protein.

Dusart P, Fagerberg L, Perisic L, Civelek M, Struck E, Hedin U, Uhlén M, Trégouët DA, Renné T, Odeberg J, Butler LM.

Sci Rep. 2018 Oct 2;8(1):14668. doi: 10.1038/s41598-018-32859-4.

25.

Integration of Transcriptomics and Antibody-Based Proteomics for Exploration of Proteins Expressed in Specialized Tissues.

Sjöstedt E, Sivertsson Å, Hikmet Noraddin F, Katona B, Näsström Å, Vuu J, Kesti D, Oksvold P, Edqvist PH, Olsson I, Uhlén M, Lindskog C.

J Proteome Res. 2018 Dec 7;17(12):4127-4137. doi: 10.1021/acs.jproteome.8b00406. Epub 2018 Oct 16.

PMID:
30272454
26.

Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage.

Matic LP, Jesus Iglesias M, Vesterlund M, Lengquist M, Hong MG, Saieed S, Sanchez-Rivera L, Berg M, Razuvaev A, Kronqvist M, Lund K, Caidahl K, Gillgren P, Pontén F, Uhlén M, Schwenk JM, Hansson GK, Paulsson-Berne G, Fagman E, Roy J, Hultgren R, Bergström G, Lehtiö J, Odeberg J, Hedin U.

JACC Basic Transl Sci. 2018 Aug 1;3(4):464-480. doi: 10.1016/j.jacbts.2018.04.001. eCollection 2018 Aug.

27.

Metabolic Network-Based Identification and Prioritization of Anticancer Targets Based on Expression Data in Hepatocellular Carcinoma.

Bidkhori G, Benfeitas R, Elmas E, Kararoudi MN, Arif M, Uhlen M, Nielsen J, Mardinoglu A.

Front Physiol. 2018 Jul 17;9:916. doi: 10.3389/fphys.2018.00916. eCollection 2018.

28.

Understanding the Representative Gut Microbiota Dysbiosis in Metformin-Treated Type 2 Diabetes Patients Using Genome-Scale Metabolic Modeling.

Rosario D, Benfeitas R, Bidkhori G, Zhang C, Uhlen M, Shoaie S, Mardinoglu A.

Front Physiol. 2018 Jun 25;9:775. doi: 10.3389/fphys.2018.00775. eCollection 2018.

29.

Ca2+-binding protein NECAB2 facilitates inflammatory pain hypersensitivity.

Zhang MD, Su J, Adori C, Cinquina V, Malenczyk K, Girach F, Peng C, Ernfors P, Löw P, Borgius L, Kiehn O, Watanabe M, Uhlén M, Mitsios N, Mulder J, Harkany T, Hökfelt T.

J Clin Invest. 2018 Aug 31;128(9):3757-3768. doi: 10.1172/JCI120913. Epub 2018 Jul 30.

30.

Drug Repositioning for Effective Prostate Cancer Treatment.

Turanli B, Grøtli M, Boren J, Nielsen J, Uhlen M, Arga KY, Mardinoglu A.

Front Physiol. 2018 May 15;9:500. doi: 10.3389/fphys.2018.00500. eCollection 2018. Review.

31.

Surface Display of Small Affinity Proteins on Synechocystis sp. Strain PCC 6803 Mediated by Fusion to the Major Type IV Pilin PilA1.

Cengic I, Uhlén M, Hudson EP.

J Bacteriol. 2018 Jul 25;200(16). pii: e00270-18. doi: 10.1128/JB.00270-18. Print 2018 Aug 15.

32.

Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia.

Danielsson F, Fasterius E, Sullivan D, Hases L, Sanli K, Zhang C, Mardinoglu A, Al-Khalili C, Huss M, Uhlén M, Williams C, Lundberg E.

Oncotarget. 2018 Apr 13;9(28):19730-19744. doi: 10.18632/oncotarget.24808. eCollection 2018 Apr 13.

33.

Systems biology in hepatology: approaches and applications.

Mardinoglu A, Boren J, Smith U, Uhlen M, Nielsen J.

Nat Rev Gastroenterol Hepatol. 2018 Jun;15(6):365-377. doi: 10.1038/s41575-018-0007-8. Review.

PMID:
29686404
34.

Mining the Human Tissue Proteome for Protein Citrullination.

Lee CY, Wang D, Wilhelm M, Zolg DP, Schmidt T, Schnatbaum K, Reimer U, Pontén F, Uhlén M, Hahne H, Kuster B.

Mol Cell Proteomics. 2018 Jul;17(7):1378-1391. doi: 10.1074/mcp.RA118.000696. Epub 2018 Apr 2.

35.

Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.

Azimi A, Caramuta S, Seashore-Ludlow B, Boström J, Robinson JL, Edfors F, Tuominen R, Kemper K, Krijgsman O, Peeper DS, Nielsen J, Hansson J, Egyhazi Brage S, Altun M, Uhlen M, Maddalo G.

Mol Syst Biol. 2018 Mar 5;14(3):e7858. doi: 10.15252/msb.20177858.

36.

Translational study reveals a two-faced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification.

Karnevi E, Dror LB, Mardinoglu A, Elebro J, Heby M, Olofsson SE, Nodin B, Eberhard J, Gallagher W, Uhlén M, Jirström K.

Oncotarget. 2017 Dec 15;9(5):6188-6200. doi: 10.18632/oncotarget.23486. eCollection 2018 Jan 19.

37.

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.

Mardinoglu A, Wu H, Bjornson E, Zhang C, Hakkarainen A, Räsänen SM, Lee S, Mancina RM, Bergentall M, Pietiläinen KH, Söderlund S, Matikainen N, Ståhlman M, Bergh PO, Adiels M, Piening BD, Granér M, Lundbom N, Williams KJ, Romeo S, Nielsen J, Snyder M, Uhlén M, Bergström G, Perkins R, Marschall HU, Bäckhed F, Taskinen MR, Borén J.

Cell Metab. 2018 Mar 6;27(3):559-571.e5. doi: 10.1016/j.cmet.2018.01.005. Epub 2018 Feb 15.

38.

How many human proteoforms are there?

Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P, Mootha VK, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE, Vidal M, Walt DR, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B.

Nat Chem Biol. 2018 Feb 14;14(3):206-214. doi: 10.1038/nchembio.2576.

39.

Broad Views of Non-alcoholic Fatty Liver Disease.

Mardinoglu A, Uhlen M, Borén J.

Cell Syst. 2018 Jan 24;6(1):7-9. doi: 10.1016/j.cels.2018.01.004.

40.

The Human Cell Atlas.

Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N; Human Cell Atlas Meeting Participants.

Elife. 2017 Dec 5;6. pii: e27041. doi: 10.7554/eLife.27041.

41.

TCSBN: a database of tissue and cancer specific biological networks.

Lee S, Zhang C, Arif M, Liu Z, Benfeitas R, Bidkhori G, Deshmukh S, Al Shobky M, Lovric A, Boren J, Nielsen J, Uhlen M, Mardinoglu A.

Nucleic Acids Res. 2018 Jan 4;46(D1):D595-D600. doi: 10.1093/nar/gkx994.

42.

In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation.

Zieba A, Ponten F, Uhlén M, Landegren U.

Mod Pathol. 2018 Feb;31(2):253-263. doi: 10.1038/modpathol.2017.102. Epub 2017 Sep 22.

43.

Human protein secretory pathway genes are expressed in a tissue-specific pattern to match processing demands of the secretome.

Feizi A, Gatto F, Uhlen M, Nielsen J.

NPJ Syst Biol Appl. 2017 Aug 18;3:22. doi: 10.1038/s41540-017-0021-4. eCollection 2017.

44.

Network analyses identify liver-specific targets for treating liver diseases.

Lee S, Zhang C, Liu Z, Klevstig M, Mukhopadhyay B, Bergentall M, Cinar R, Ståhlman M, Sikanic N, Park JK, Deshmukh S, Harzandi AM, Kuijpers T, Grøtli M, Elsässer SJ, Piening BD, Snyder M, Smith U, Nielsen J, Bäckhed F, Kunos G, Uhlen M, Boren J, Mardinoglu A.

Mol Syst Biol. 2017 Aug 21;13(8):938. doi: 10.15252/msb.20177703.

45.

A pathology atlas of the human cancer transcriptome.

Uhlen M, Zhang C, Lee S, Sjöstedt E, Fagerberg L, Bidkhori G, Benfeitas R, Arif M, Liu Z, Edfors F, Sanli K, von Feilitzen K, Oksvold P, Lundberg E, Hober S, Nilsson P, Mattsson J, Schwenk JM, Brunnström H, Glimelius B, Sjöblom T, Edqvist PH, Djureinovic D, Micke P, Lindskog C, Mardinoglu A, Ponten F.

Science. 2017 Aug 18;357(6352). pii: eaan2507. doi: 10.1126/science.aan2507.

PMID:
28818916
46.

Combination of phage and Gram-positive bacterial display of human antibody repertoires enables isolation of functional high affinity binders.

Hu FJ, Volk AL, Persson H, Säll A, Borrebaeck C, Uhlen M, Rockberg J.

N Biotechnol. 2018 Oct 25;45:80-88. doi: 10.1016/j.nbt.2017.07.011. Epub 2017 Aug 1.

47.

New Challenges to Study Heterogeneity in Cancer Redox Metabolism.

Benfeitas R, Uhlen M, Nielsen J, Mardinoglu A.

Front Cell Dev Biol. 2017 Jul 11;5:65. doi: 10.3389/fcell.2017.00065. eCollection 2017. Review.

48.

Untargeted screening for novel autoantibodies with prognostic value in first-episode psychosis.

Zandian A, Wingård L, Nilsson H, Sjöstedt E, Johansson DX, Just D, Hellström C, Uhlén M, Schwenk JM, Häggmark-Månberg A, Norbeck O, Owe-Larsson B, Nilsson P, Persson MAA.

Transl Psychiatry. 2017 Jul 25;7(7):e1177. doi: 10.1038/tp.2017.160.

49.

Improving the economics of NASH/NAFLD treatment through the use of systems biology.

Bosley J, Boren C, Lee S, Grøtli M, Nielsen J, Uhlen M, Boren J, Mardinoglu A.

Drug Discov Today. 2017 Oct;22(10):1532-1538. doi: 10.1016/j.drudis.2017.07.005. Epub 2017 Jul 20. Review.

PMID:
28736156
50.

Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes.

Väremo L, Henriksen TI, Scheele C, Broholm C, Pedersen M, Uhlén M, Pedersen BK, Nielsen J.

Genome Med. 2017 May 25;9(1):47. doi: 10.1186/s13073-017-0432-2.

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