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Items: 1 to 50 of 345

1.

Effect of ASP6432, a Novel Type 1 Lysophosphatidic Acid Receptor Antagonist, on Urethral Function and Prostate Cell Proliferation.

Sakamoto K, Noguchi Y, Ueshima K, Yamakuni H, Ohtake A, Sato S, Ishizu K, Hosogai N, Kawaminami E, Takeda M, Masuda N.

J Pharmacol Exp Ther. 2018 Jun 8. pii: jpet.118.247908. doi: 10.1124/jpet.118.247908. [Epub ahead of print]

2.

Total resection of any segment of the lateral meniscus may cause early cartilage degeneration: Evaluation by magnetic resonance imaging using T2 mapping.

Murakami K, Arai Y, Ikoma K, Kato K, Inoue H, Nakagawa S, Fujii Y, Ueshima K, Fujiwara H, Kubo T.

Medicine (Baltimore). 2018 Jun;97(23):e11011. doi: 10.1097/MD.0000000000011011.

3.

Long-term effects of antihypertensive therapy on cardiovascular events and new-onset diabetes mellitus in high-risk hypertensive patients in Japan.

Liu J, Yasuno S, Oba K, Konda M, Ichihara C, Kitao H, Kuwabara Y, Ueshima K.

J Hypertens. 2018 May 9. doi: 10.1097/HJH.0000000000001780. [Epub ahead of print]

PMID:
29750680
4.

Evaluation of femoral perfusion using dynamic contrast-enhanced MRI after simultaneous initiation of electrical stimulation and steroid treatment in an osteonecrosis model.

Yamamoto H, Ueshima K, Saito M, Ikoma K, Ishida M, Goto T, Hayashi S, Ikegami A, Fujioka M, Mazda O, Kubo T.

Electromagn Biol Med. 2018;37(2):84-94. doi: 10.1080/15368378.2018.1466310. Epub 2018 Apr 30.

PMID:
29708772
5.

Sorafenib plus low-dose cisplatin and fluorouracil hepatic arterial infusion chemotherapy versus sorafenib alone in patients with advanced hepatocellular carcinoma (SILIUS): a randomised, open label, phase 3 trial.

Kudo M, Ueshima K, Yokosuka O, Ogasawara S, Obi S, Izumi N, Aikata H, Nagano H, Hatano E, Sasaki Y, Hino K, Kumada T, Yamamoto K, Imai Y, Iwadou S, Ogawa C, Okusaka T, Kanai F, Akazawa K, Yoshimura KI, Johnson P, Arai Y; SILIUS study group.

Lancet Gastroenterol Hepatol. 2018 Jun;3(6):424-432. doi: 10.1016/S2468-1253(18)30078-5. Epub 2018 Apr 7.

PMID:
29631810
6.

Intensive Treat-to-Target Statin Therapy in High-Risk Japanese Patients With Hypercholesterolemia and Diabetic Retinopathy: Report of a Randomized Study.

Itoh H, Komuro I, Takeuchi M, Akasaka T, Daida H, Egashira Y, Fujita H, Higaki J, Hirata KI, Ishibashi S, Isshiki T, Ito S, Kashiwagi A, Kato S, Kitagawa K, Kitakaze M, Kitazono T, Kurabayashi M, Miyauchi K, Murakami T, Murohara T, Node K, Ogawa S, Saito Y, Seino Y, Shigeeda T, Shindo S, Sugawara M, Sugiyama S, Terauchi Y, Tsutsui H, Ueshima K, Utsunomiya K, Yamagishi M, Yamazaki T, Yo S, Yokote K, Yoshida K, Yoshimura M, Yoshimura N, Nakao K, Nagai R; EMPATHY Investigators.

Diabetes Care. 2018 Jun;41(6):1275-1284. doi: 10.2337/dc17-2224. Epub 2018 Apr 6.

PMID:
29626074
7.

Early detection of osteoarthritis in rabbits using MRI with a double-contrast agent.

Onishi O, Ikoma K, Kido M, Kabuto Y, Ueshima K, Matsuda KI, Tanaka M, Kubo T.

BMC Musculoskelet Disord. 2018 Mar 13;19(1):81. doi: 10.1186/s12891-018-2002-1.

8.

Sustained antiviral effects and clearance of hepatitis surface antigen after combination therapy with entecavir and pegylated interferon in chronic hepatitis B.

Hagiwara S, Nishida N, Watanabe T, Ida H, Sakurai T, Ueshima K, Takita M, Komeda Y, Nishijima N, Osaki Y, Kudo M.

Antivir Ther. 2018 Feb 13. doi: 10.3851/IMP3225. [Epub ahead of print]

PMID:
29438098
9.

Effectiveness of nationwide screening and lifestyle intervention for abdominal obesity and cardiometabolic risks in Japan: The metabolic syndrome and comprehensive lifestyle intervention study on nationwide database in Japan (MetS ACTION-J study).

Nakao YM, Miyamoto Y, Ueshima K, Nakao K, Nakai M, Nishimura K, Yasuno S, Hosoda K, Ogawa Y, Itoh H, Ogawa H, Kangawa K, Nakao K.

PLoS One. 2018 Jan 9;13(1):e0190862. doi: 10.1371/journal.pone.0190862. eCollection 2018.

10.

Effects of monthly feedback of VFA measured by dual BIA method in Japanese patients with obesity: a randomized controlled study.

Moriyasu T, Hosoda K, Tanaka-Mizuno S, Konda M, Ueshima K, Ida M, Nin K.

Obes Sci Pract. 2017 Sep 14;3(4):407-416. doi: 10.1002/osp4.126. eCollection 2017 Dec.

11.

Hand-Foot Syndrome and Post-Progression Treatment Are the Good Predictors of Better Survival in Advanced Hepatocellular Carcinoma Treated with Sorafenib: A Multicenter Study.

Ogawa C, Morita M, Omura A, Noda T, Kubo A, Matsunaka T, Tamaki H, Shibatoge M, Tsutsui A, Senoh T, Nagano T, Takaguchi K, Tani J, Morishita A, Yoneyama H, Masaki T, Moriya A, Ando M, Deguchi A, Kokudo Y, Minami Y, Ueshima K, Sakurai T, Nishida N, Kudo M.

Oncology. 2017;93 Suppl 1:113-119. doi: 10.1159/000481241. Epub 2017 Dec 20.

12.

Fixed-flexion view X-ray of the knee superior in detection and follow-up of knee osteoarthritis.

Kan H, Arai Y, Kobayashi M, Nakagawa S, Inoue H, Hino M, Komaki S, Ikoma K, Ueshima K, Fujiwara H, Yokota I, Kubo T.

Medicine (Baltimore). 2017 Dec;96(49):e9126. doi: 10.1097/MD.0000000000009126.

13.

Ultrasound-ultrasound image overlay fusion improves real-time control of radiofrequency ablation margin in the treatment of hepatocellular carcinoma.

Minami Y, Minami T, Hagiwara S, Ida H, Ueshima K, Nishida N, Murakami T, Kudo M.

Eur Radiol. 2018 May;28(5):1986-1993. doi: 10.1007/s00330-017-5162-8. Epub 2017 Dec 1.

PMID:
29196855
14.

Evaluation of NISHIJIN e-textile for 12-lead ECG measurement through automatic ECG analyzer.

Kuroda T, Shiomi H, Minamino-Muta E, Yamashita Y, Iwao T, Tamura H, Ueshima K, Kimura T.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:1234-1237. doi: 10.1109/EMBC.2017.8037054.

PMID:
29060099
15.

Sorafenib-Regorafenib Sequential Therapy in Advanced Hepatocellular Carcinoma: A Single-Institute Experience.

Ueshima K, Nishida N, Kudo M.

Dig Dis. 2017;35(6):611-617. doi: 10.1159/000480257. Epub 2017 Oct 17.

PMID:
29040994
16.

Time to Transcatheter Arterial Chemoembolization Refractoriness in Patients with Hepatocellular Carcinoma in Kinki Criteria Stages B1 and B2.

Arizumi T, Minami T, Chishina H, Kono M, Takita M, Yada N, Hagiwara S, Minami Y, Ida H, Ueshima K, Kamata K, Minaga K, Komeda Y, Takenaka M, Sakurai T, Watanabe T, Nishida N, Kudo M.

Dig Dis. 2017;35(6):589-597. doi: 10.1159/000480208. Epub 2017 Oct 17.

PMID:
29040992
17.

Impact of Tumor Factors on Survival in Patients with Hepatocellular Carcinoma Classified Based on Kinki Criteria Stage B2.

Arizumi T, Minami T, Chishina H, Kono M, Takita M, Yada N, Hagiwara S, Minami Y, Ida H, Ueshima K, Kamata K, Minaga K, Komeda Y, Takenaka M, Sakurai T, Watanabe T, Nishida N, Kudo M.

Dig Dis. 2017;35(6):583-588. doi: 10.1159/000480186. Epub 2017 Oct 17.

PMID:
29040991
18.

Hepatocellular Carcinoma after Achievement of Sustained Viral Response with Daclatasvir and Asunaprevir in Patients with Chronic Hepatitis C Virus Infection.

Ida H, Hagiwara S, Kono M, Minami T, Chishina H, Arizumi T, Takita M, Yada N, Minami Y, Ueshima K, Nishida N, Kudo M.

Dig Dis. 2017;35(6):565-573. doi: 10.1159/000480183. Epub 2017 Oct 17.

PMID:
29040989
19.

Unique Characteristics Associated with Sustained Liver Damage in Chronic Hepatitis C Patients Treated with Direct Acting Antivirals.

Kono M, Nishida N, Hagiwara S, Minami T, Chishina H, Arizumi T, Minaga K, Kamata K, Komeda Y, Sakurai T, Takenaka M, Takita M, Yada N, Ida H, Minami Y, Ueshima K, Watanabe T, Kudo M.

Dig Dis. 2017;35(6):556-564. doi: 10.1159/000480148. Epub 2017 Oct 17.

PMID:
29040988
20.

Hepatocarcinogenesis Is Associated with Serum Albumin Levels after Sustained Virological Responses with Interferon-Based Therapy in Patients with Hepatitis C.

Umehara Y, Hagiwara S, Nishida N, Sakurai T, Ida H, Minami Y, Takita M, Minami T, Chishina H, Ueshima K, Komeda Y, Arizumi T, Watanabe T, Kudo M.

Dig Dis. 2017;35(6):548-555. doi: 10.1159/000480147. Epub 2017 Oct 17.

PMID:
29040987
21.

Atriofascicular Mahaim with Ebstein anomaly: A case report.

Ueshima K, Nakamura Y, Takeno S, Miyake T, Takemura T.

J Arrhythm. 2017 Oct;33(5):508-510. doi: 10.1016/j.joa.2017.06.007. Epub 2017 Aug 8.

22.

Changes in Basic Movement Ability and Activities of Daily Living After Hip Fractures: Correlation Between Basic Movement Scale and Motor-Functional Independence Measure Scores.

Toyama S, Sawada K, Ueshima K, Mikami Y, Mori I, Takamuku K, Takahashi T, Kubo T.

Am J Phys Med Rehabil. 2018 May;97(5):316-322. doi: 10.1097/PHM.0000000000000829.

PMID:
28930758
23.

Evidence and topics of chemotherapy for hepatocellular carcinoma.

Ueshima K, Kudo M.

Nihon Shokakibyo Gakkai Zasshi. 2017;114(9):1621-1628. doi: 10.11405/nisshoshi.114.1621. Japanese. No abstract available.

PMID:
28883291
24.

Length change patterns and shape of a grafted tendon after anatomical medial patellofemoral ligament reconstruction differs from that in a healthy knee.

Nakagawa S, Arai Y, Inoue H, Hino M, Fujii Y, Komaki S, Ikoma K, Ueshima K, Fujiwara H, Kubo T.

Knee Surg Sports Traumatol Arthrosc. 2018 Apr;26(4):1245-1251. doi: 10.1007/s00167-017-4620-9. Epub 2017 Jul 24.

PMID:
28741155
25.

The Overall Survival of Patients with Hepatocellular Carcinoma Correlates with the Newly Defined Time to Progression after Transarterial Chemoembolization.

Arizumi T, Ueshima K, Iwanishi M, Minami T, Chishina H, Kono M, Takita M, Yada N, Hagiwara S, Minami Y, Ida H, Komeda Y, Takenaka M, Sakurai T, Watanabe T, Nishida N, Kudo M.

Liver Cancer. 2017 Jun;6(3):227-235. doi: 10.1159/000475777. Epub 2017 May 9.

26.

Reliability of radiographic evaluations of the stage of osteoarthritis of the hip joint and an approach to improve the staging criteria.

Yoshitani J, Nakamura T, Ueshima K, Ebara H, Kabata T, Tsuchiya H.

J Orthop Sci. 2017 Sep;22(5):905-908. doi: 10.1016/j.jos.2017.05.007. Epub 2017 May 24.

PMID:
28551281
27.

Underuse of Cardiac Rehabilitation in Workers With Coronary Artery Disease - Claims Database Survey in Japan.

Kanazawa N, Ueshima K, Tominari S, Nakayama T.

Circ J. 2017 Sep 25;81(10):1424-1431. doi: 10.1253/circj.CJ-16-1260. Epub 2017 May 11.

28.

Radiographic Measurement of Joint Space Width Using the Fixed Flexion View in 1,102 Knees of Japanese Patients with Osteoarthritis in Comparison with the Standing Extended View.

Kan H, Arai Y, Kobayashi M, Nakagawa S, Inoue H, Hino M, Komaki S, Ikoma K, Ueshima K, Fujiwara H, Kubo T.

Knee Surg Relat Res. 2017 Mar 1;29(1):63-68. doi: 10.5792/ksrr.16.046.

29.

Proposal of quality indicators for cardiac rehabilitation after acute coronary syndrome in Japan: a modified Delphi method and practice test.

Ohtera S, Kanazawa N, Ozasa N, Ueshima K, Nakayama T.

BMJ Open. 2017 Jan 27;7(1):e013036. doi: 10.1136/bmjopen-2016-013036.

30.

Influence of Liver Inflammation on Liver Stiffness Measurement in Patients with Autoimmune Hepatitis Evaluation by Combinational Elastography.

Yada N, Sakurai T, Minami T, Arizumi T, Takita M, Hagiwara S, Ida H, Ueshima K, Nishida N, Kudo M.

Oncology. 2017;92 Suppl 1:10-15. doi: 10.1159/000451011. Epub 2017 Jan 6.

31.

Endothelium-Derived C-Type Natriuretic Peptide Contributes to Blood Pressure Regulation by Maintaining Endothelial Integrity.

Nakao K, Kuwahara K, Nishikimi T, Nakagawa Y, Kinoshita H, Minami T, Kuwabara Y, Yamada C, Yamada Y, Tokudome T, Nagai-Okatani C, Minamino N, Nakao YM, Yasuno S, Ueshima K, Sone M, Kimura T, Kangawa K, Nakao K.

Hypertension. 2017 Feb;69(2):286-296. doi: 10.1161/HYPERTENSIONAHA.116.08219. Epub 2017 Jan 3.

32.

Malignant Transformation of Hepatocellular Adenoma.

Kwok WY, Hagiwara S, Nishida N, Watanabe T, Sakurai T, Ida H, Minami Y, Takita M, Minami T, Iwanishi M, Chishina H, Kono M, Ueshima K, Komeda Y, Arizumi T, Enoki E, Nakai T, Kumabe T, Nakashima O, Kondo F, Kudo M.

Oncology. 2017;92 Suppl 1:16-28. doi: 10.1159/000451012. Epub 2016 Dec 17.

33.

Contrast-Enhanced Tissue Harmonic Imaging versus Phase Inversion Harmonic Sonographic Imaging for the Delineation of Hepatocellular Carcinomas.

Kono M, Minami Y, Iwanishi M, Minami T, Chishina H, Arizumi T, Komeda Y, Sakurai T, Takita M, Yada N, Ida H, Hagiwara S, Ueshima K, Nishida N, Kudo M.

Oncology. 2017;92 Suppl 1:29-34. doi: 10.1159/000451014. Epub 2016 Dec 15.

34.

Outcome of Combination Therapy with Sofosbuvir and Ledipasvir for Chronic Type C Liver Disease.

Hagiwara S, Nishida N, Watanabe T, Sakurai T, Ida H, Minami Y, Takita M, Minami T, Iwanishi M, Chishina H, Ueshima K, Komeda Y, Arizumi T, Kudo M.

Oncology. 2017;92 Suppl 1:3-9. doi: 10.1159/000451010. Epub 2016 Dec 15.

35.

Modular stem fracture at stem-sleeve junction after primary total hip arthroplasty.

Yoshitani J, Nakamura T, Maruhashi Y, Sasagawa T, Ueshima K, Funaki K.

J Orthop Sci. 2016 Oct 25. pii: S0949-2658(16)30190-7. doi: 10.1016/j.jos.2016.10.003. [Epub ahead of print] No abstract available.

PMID:
27789206
36.

Impact of Tight Junction Protein ZO-1 and TWIST Expression on Postoperative Survival of Patients with Hepatocellular Carcinoma.

Nagai T, Arao T, Nishio K, Matsumoto K, Hagiwara S, Sakurai T, Minami Y, Ida H, Ueshima K, Nishida N, Sakai K, Saijo N, Kudo K, Kaneda H, Tamura D, Aomatsu K, Kimura H, Fujita Y, Haji S, Kudo M.

Dig Dis. 2016;34(6):702-707. Epub 2016 Oct 17.

PMID:
27750241
37.

US-US Fusion Imaging in Radiofrequency Ablation for Liver Metastases.

Minami Y, Minami T, Chishina H, Kono M, Arizumi T, Takita M, Yada N, Hagiwara S, Ida H, Ueshima K, Nishida N, Kudo M.

Dig Dis. 2016;34(6):687-691. Epub 2016 Oct 17.

PMID:
27750238
38.

Validation of Kinki Criteria, a Modified Substaging System, in Patients with Intermediate Stage Hepatocellular Carcinoma.

Arizumi T, Ueshima K, Iwanishi M, Minami T, Chishina H, Kono M, Takita M, Kitai S, Inoue T, Yada N, Hagiwara S, Minami Y, Ida H, Sakurai T, Kitano M, Nishida N, Kudo M.

Dig Dis. 2016;34(6):671-678. Epub 2016 Oct 17.

PMID:
27750236
39.

Clinical Factors Predicting the Effect of Tolvaptan for Refractory Ascites in Patients with Decompensated Liver Cirrhosis.

Chishina H, Hagiwara S, Nishida N, Ueshima K, Sakurai T, Ida H, Minami Y, Takita M, Kono M, Minami T, Iwanishi M, Umehara Y, Watanabe T, Komeda Y, Arizumi T, Kudo M.

Dig Dis. 2016;34(6):659-664. Epub 2016 Oct 17.

PMID:
27750234
40.

Monoethanolamine Oleate Sclerotherapy for Polycystic Liver Disease.

Takita M, Iwanishi M, Minami T, Kono M, Chishina H, Arizumi T, Yada N, Hagiwara S, Minami Y, Ida H, Ueshima K, Naoshi N, Kudo M.

Dig Dis. 2016;34(6):654-658. Epub 2016 Oct 17.

PMID:
27750233
41.

Prospective Risk Analysis of Hepatocellular Carcinoma in Patients with Chronic Hepatitis C by Ultrasound Strain Elastography.

Yada N, Sakurai T, Minami T, Arizumi T, Takita M, Hagiwara S, Ida H, Ueshima K, Nishida N, Kudo M.

Dig Dis. 2016;34(6):650-653. Epub 2016 Oct 17.

PMID:
27750232
42.

Safety, Tolerability, and Efficacy of Sofosbuvir Plus Ribavirin in Elderly Patients Infected with Hepatitis C Virus Genotype 2.

Nishida N, Kono M, Minami T, Chishina H, Arizumi T, Takita M, Yada N, Ida H, Hagiwara S, Minami Y, Ueshima K, Sakurai T, Kudo M.

Dig Dis. 2016;34(6):632-639. Epub 2016 Oct 17.

PMID:
27750230
43.

Outcome of Asunaprevir/Daclatasvir Combination Therapy for Chronic Liver Disease Type C.

Hagiwara S, Nishida N, Watanabe T, Sakurai T, Ida H, Minami Y, Takita M, Minami T, Iwanishi M, Chishina H, Ueshima K, Komeda Y, Arizumi T, Kudo M.

Dig Dis. 2016;34(6):620-626. Epub 2016 Oct 17.

PMID:
27750228
44.

Publisher's Note: Search for Majorana Neutrinos Near the Inverted Mass Hierarchy Region with KamLAND-Zen [Phys. Rev. Lett. 117, 082503 (2016)].

Gando A, Gando Y, Hachiya T, Hayashi A, Hayashida S, Ikeda H, Inoue K, Ishidoshiro K, Karino Y, Koga M, Matsuda S, Mitsui T, Nakamura K, Obara S, Oura T, Ozaki H, Shimizu I, Shirahata Y, Shirai J, Suzuki A, Takai T, Tamae K, Teraoka Y, Ueshima K, Watanabe H, Kozlov A, Takemoto Y, Yoshida S, Fushimi K, Banks TI, Berger BE, Fujikawa BK, O'Donnell T, Winslow LA, Efremenko Y, Karwowski HJ, Markoff DM, Tornow W, Detwiler JA, Enomoto S, Decowski MP; KamLAND-Zen Collaboration.

Phys Rev Lett. 2016 Sep 2;117(10):109903. Epub 2016 Sep 2.

PMID:
27636501
45.

Acetabular anteversion angle from early stage of Perthes disease to adolescence.

Yoshida T, Kim WC, Nishida A, Oka Y, Shirai T, Ikoma K, Ueshima K, Fujiwara H, Kubo T.

J Orthop. 2016 Aug 29;13(4):410-3. doi: 10.1016/j.jor.2016.08.001. eCollection 2016 Dec.

46.

Search for Majorana Neutrinos Near the Inverted Mass Hierarchy Region with KamLAND-Zen.

Gando A, Gando Y, Hachiya T, Hayashi A, Hayashida S, Ikeda H, Inoue K, Ishidoshiro K, Karino Y, Koga M, Matsuda S, Mitsui T, Nakamura K, Obara S, Oura T, Ozaki H, Shimizu I, Shirahata Y, Shirai J, Suzuki A, Takai T, Tamae K, Teraoka Y, Ueshima K, Watanabe H, Kozlov A, Takemoto Y, Yoshida S, Fushimi K, Banks TI, Berger BE, Fujikawa BK, O'Donnell T, Winslow LA, Efremenko Y, Karwowski HJ, Markoff DM, Tornow W, Detwiler JA, Enomoto S, Decowski MP; KamLAND-Zen Collaboration.

Phys Rev Lett. 2016 Aug 19;117(8):082503. doi: 10.1103/PhysRevLett.117.082503. Epub 2016 Aug 16. Erratum in: Phys Rev Lett. 2016 Sep 2;117(10):109903.

PMID:
27588852
47.

Effects of atorvastatin on renal function in patients with dyslipidemia and chronic kidney disease: assessment of clinical usefulness in CKD patients with atorvastatin (ASUCA) trial.

Kimura G, Kasahara M, Ueshima K, Tanaka S, Yasuno S, Fujimoto A, Sato T, Imamoto M, Kosugi S, Nakao K.

Clin Exp Nephrol. 2017 Jun;21(3):417-424. doi: 10.1007/s10157-016-1304-6. Epub 2016 Jul 8.

48.

Differences in monthly variation, cause, and place of injury between femoral neck and trochanteric fractures: 6-year survey (2008-2013) in Kyoto prefecture, Japan.

Horii M, Fujiwara H, Mikami Y, Ikeda T, Ueshima K, Ikoma K, Shirai T, Nagae M, Oka Y, Sawada K, Kuriyama N, Kubo T.

Clin Cases Miner Bone Metab. 2016 Jan-Apr;13(1):19-24. doi: 10.11138/ccmbm/2016.13.1.019. Epub 2016 May 11.

49.

Semiquantitative prediction of early response of conventional transcatheter arterial chemoembolization for hepatocellular carcinoma using postprocedural plain cone-beam computed tomography.

Minami Y, Takita M, Tsurusaki M, Yagyu Y, Ueshima K, Murakami T, Kudo M.

Hepatol Res. 2017 Mar;47(3):E113-E119. doi: 10.1111/hepr.12735. Epub 2016 Jun 20.

PMID:
27138382
50.

Adaptive servoventilation versus oxygen therapy for sleep disordered breathing in patients with heart failure: a randomised trial.

Murase K, Ono K, Yoneda T, Iguchi M, Yokomatsu T, Mizoguchi T, Izumi T, Akao M, Miki S, Nohara R, Ueshima K, Mishima M, Kimura T, White DP, Chin K.

Open Heart. 2016 Mar 31;3(1):e000366. doi: 10.1136/openhrt-2015-000366. eCollection 2016.

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