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Items: 1 to 50 of 192

1.

Parathyroid Hormone Shifts Cell Fate of a Leptin Receptor-Marked Stromal Population from Adipogenic to Osteoblastic Lineage.

Yang M, Arai A, Udagawa N, Zhao L, Nishida D, Murakami K, Hiraga T, Takao-Kawabata R, Matsuo K, Komori T, Kobayashi Y, Takahashi N, Isogai Y, Ishizuya T, Yamaguchi A, Mizoguchi T.

J Bone Miner Res. 2019 Jun 7. doi: 10.1002/jbmr.3811. [Epub ahead of print]

PMID:
31173642
2.

Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment.

Ochiai N, Nakachi Y, Yokoo T, Ichihara T, Eriksson T, Yonemoto Y, Kato T, Ogata H, Fujimoto N, Kobayashi Y, Udagawa N, Kaku S, Ueki T, Okazaki Y, Takahashi N, Suda T.

Commun Biol. 2019 Mar 1;2:86. doi: 10.1038/s42003-019-0334-5. eCollection 2019.

3.

Olfactomedin-like protein OLFML1 inhibits Hippo signaling and mineralization in osteoblasts.

Murakami K, Kikugawa S, Kobayashi Y, Uehara S, Suzuki T, Kato H, Udagawa N, Nakamura Y.

Biochem Biophys Res Commun. 2018 Oct 28;505(2):419-425. doi: 10.1016/j.bbrc.2018.09.112. Epub 2018 Sep 25.

4.

Coupling of bone resorption and formation by RANKL reverse signalling.

Ikebuchi Y, Aoki S, Honma M, Hayashi M, Sugamori Y, Khan M, Kariya Y, Kato G, Tabata Y, Penninger JM, Udagawa N, Aoki K, Suzuki H.

Nature. 2018 Sep;561(7722):195-200. doi: 10.1038/s41586-018-0482-7. Epub 2018 Sep 5.

PMID:
30185903
5.

Non-canonical Wnt signals regulate cytoskeletal remodeling in osteoclasts.

Uehara S, Udagawa N, Kobayashi Y.

Cell Mol Life Sci. 2018 Oct;75(20):3683-3692. doi: 10.1007/s00018-018-2881-1. Epub 2018 Jul 26. Review.

6.

[Topics for basic research(osteoclast and bone resorption)in ASBMR 2017.]

Udagawa N.

Clin Calcium. 2018;28(1):104-108. doi: CliCa1801104108. Japanese.

PMID:
29279433
7.

Mechanisms involved in bone resorption regulated by vitamin D.

Nakamichi Y, Udagawa N, Suda T, Takahashi N.

J Steroid Biochem Mol Biol. 2018 Mar;177:70-76. doi: 10.1016/j.jsbmb.2017.11.005. Epub 2017 Nov 14. Review.

PMID:
29146302
8.

Treatment of OPG-deficient mice with WP9QY, a RANKL-binding peptide, recovers alveolar bone loss by suppressing osteoclastogenesis and enhancing osteoblastogenesis.

Ozaki Y, Koide M, Furuya Y, Ninomiya T, Yasuda H, Nakamura M, Kobayashi Y, Takahashi N, Yoshinari N, Udagawa N.

PLoS One. 2017 Sep 22;12(9):e0184904. doi: 10.1371/journal.pone.0184904. eCollection 2017.

9.

Protein kinase N3 promotes bone resorption by osteoclasts in response to Wnt5a-Ror2 signaling.

Uehara S, Udagawa N, Mukai H, Ishihara A, Maeda K, Yamashita T, Murakami K, Nishita M, Nakamura T, Kato S, Minami Y, Takahashi N, Kobayashi Y.

Sci Signal. 2017 Aug 29;10(494). pii: eaan0023. doi: 10.1126/scisignal.aan0023.

PMID:
28851822
10.

A Jak1/2 inhibitor, baricitinib, inhibits osteoclastogenesis by suppressing RANKL expression in osteoblasts in vitro.

Murakami K, Kobayashi Y, Uehara S, Suzuki T, Koide M, Yamashita T, Nakamura M, Takahashi N, Kato H, Udagawa N, Nakamura Y.

PLoS One. 2017 Jul 14;12(7):e0181126. doi: 10.1371/journal.pone.0181126. eCollection 2017.

11.

Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy.

Yang M, Arai A, Udagawa N, Hiraga T, Lijuan Z, Ito S, Komori T, Moriishi T, Matsuo K, Shimoda K, Zahalka AH, Kobayashi Y, Takahashi N, Mizoguchi T.

Sci Rep. 2017 Jul 10;7(1):4928. doi: 10.1038/s41598-017-05401-1.

12.

Bone Formation Is Coupled to Resorption Via Suppression of Sclerostin Expression by Osteoclasts.

Koide M, Kobayashi Y, Yamashita T, Uehara S, Nakamura M, Hiraoka BY, Ozaki Y, Iimura T, Yasuda H, Takahashi N, Udagawa N.

J Bone Miner Res. 2017 Oct;32(10):2074-2086. doi: 10.1002/jbmr.3175. Epub 2017 Jun 15.

13.

Histochemical assessment for osteoblastic activity coupled with dysfunctional osteoclasts in c-src deficient mice.

Toray H, Hasegawa T, Sakagami N, Tsuchiya E, Kudo A, Zhao S, Moritani Y, Abe M, Yoshida T, Yamamoto T, Yamamoto T, Oda K, Udagawa N, Luiz de Freitas PH, Li M.

Biomed Res. 2017;38(2):123-134. doi: 10.2220/biomedres.38.123.

14.

VDR in Osteoblast-Lineage Cells Primarily Mediates Vitamin D Treatment-Induced Increase in Bone Mass by Suppressing Bone Resorption.

Nakamichi Y, Udagawa N, Horibe K, Mizoguchi T, Yamamoto Y, Nakamura T, Hosoya A, Kato S, Suda T, Takahashi N.

J Bone Miner Res. 2017 Jun;32(6):1297-1308. doi: 10.1002/jbmr.3096. Epub 2017 Feb 22.

15.

Platypus and opossum calcitonins exhibit strong activities, even though they belong to mammals.

Yamashita T, Udagawa N, Thirukonda GJ, Uehara S, Yamauchi H, Suzuki N, Li F, Kobayashi Y, Takahashi N.

Gen Comp Endocrinol. 2017 May 15;246:270-278. doi: 10.1016/j.ygcen.2017.01.001. Epub 2017 Jan 4.

PMID:
28062306
16.

[Topics for basic research(osteoclast and bone resorption)in ASBMR 2016.]

Udagawa N.

Clin Calcium. 2017;27(1):128-132. doi: CliCa1701128132. Japanese.

PMID:
28017955
17.

[Pharmacokinetics of bisphosphonate.]

Nakamura M, Koide M, Udagawa N.

Clin Calcium. 2016;26(11):1561-1570. Japanese.

PMID:
27777389
18.

Response to Letter to the Editor: Re: Differences in the risk of osteoporotic femur fractures among Japanese and white women as predicted by carotid artery calcification visualized on panoramic images.

Iwamoto Y, Uchida K, Sugino N, Kuroiwa H, Kitamura Y, Udagawa N, Shinohara A, Higashi Y, Taguchi A.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Nov;122(5):655-656. doi: 10.1016/j.oooo.2016.07.025. Epub 2016 Aug 6. No abstract available.

PMID:
27765338
19.

Peptide drugs accelerate BMP-2-induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling.

Sugamori Y, Mise-Omata S, Maeda C, Aoki S, Tabata Y, Murali R, Yasuda H, Udagawa N, Suzuki H, Honma M, Aoki K.

Bioessays. 2016 Aug;38(8):717-25. doi: 10.1002/bies.201600104. Epub 2016 Jun 27.

20.

Osteoporosis, osteoporotic fractures, and carotid artery calcification detected on panoramic radiographs in Japanese men and women.

Iwamoto Y, Uchida K, Sugino N, Kuroiwa H, Kitamura Y, Udagawa N, Shinohara A, Higashi Y, Taguchi A.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Jun;121(6):673-80. doi: 10.1016/j.oooo.2016.02.006. Epub 2016 Feb 23.

PMID:
27055732
21.

Angiotensin II Stimulation of Cardiac Hypertrophy and Functional Decompensation in Osteoprotegerin-Deficient Mice.

Tsuruda T, Sekita-Hatakeyama Y, Hao Y, Sakamoto S, Kurogi S, Nakamura M, Udagawa N, Funamoto T, Sekimoto T, Hatakeyama K, Chosa E, Kato J, Asada Y, Kitamura K.

Hypertension. 2016 May;67(5):848-56. doi: 10.1161/HYPERTENSIONAHA.115.06689. Epub 2016 Mar 21.

PMID:
27001297
22.

Cardiac hypertrophy is exacerbated in aged mice lacking the osteoprotegerin gene.

Hao Y, Tsuruda T, Sekita-Hatakeyama Y, Kurogi S, Kubo K, Sakamoto S, Nakamura M, Udagawa N, Sekimoto T, Hatakeyama K, Chosa E, Asada Y, Kitamura K.

Cardiovasc Res. 2016 May 1;110(1):62-72. doi: 10.1093/cvr/cvw025. Epub 2016 Jan 29.

PMID:
26825553
23.

[Topics for basic research(osteoclast and bone resorption)in ASBMR 2015].

Udagawa N.

Clin Calcium. 2016 Jan;26(1):128-32. doi: CliCa1601128132. Japanese.

PMID:
26728539
24.

Regulation of bone metabolism by Wnt signals.

Kobayashi Y, Uehara S, Udagawa N, Takahashi N.

J Biochem. 2016 Apr;159(4):387-92. doi: 10.1093/jb/mvv124. Epub 2015 Dec 28. Review.

25.

[Bone and Calcium Metabolisms Associated with Dental and Oral-Maxillofacial Diseases. Destructive bone resorption by osteoclasts and oral disease].

Nakamura M, Koide M, Nakamura H, Udagawa N.

Clin Calcium. 2015 Sep;25(9):1376-84. doi: CliCa150913761384. Japanese.

PMID:
26320538
26.

Dendritic cell-based immunotherapy targeting Wilms' tumor 1 in patients with recurrent malignant glioma.

Sakai K, Shimodaira S, Maejima S, Udagawa N, Sano K, Higuchi Y, Koya T, Ochiai T, Koide M, Uehara S, Nakamura M, Sugiyama H, Yonemitsu Y, Okamoto M, Hongo K.

J Neurosurg. 2015 Oct;123(4):989-97. doi: 10.3171/2015.1.JNS141554. Epub 2015 Aug 7.

PMID:
26252465
27.

Wnt16 regulates osteoclast differentiation in conjunction with Wnt5a.

Kobayashi Y, Thirukonda GJ, Nakamura Y, Koide M, Yamashita T, Uehara S, Kato H, Udagawa N, Takahashi N.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):1278-83. doi: 10.1016/j.bbrc.2015.06.102. Epub 2015 Jun 18.

PMID:
26093292
28.

The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts.

Thirukonda GJ, Uehara S, Nakayama T, Yamashita T, Nakamura Y, Mizoguchi T, Takahashi N, Yagami K, Udagawa N, Kobayashi Y.

J Bone Miner Metab. 2016 Jul;34(4):395-405. doi: 10.1007/s00774-015-0683-1. Epub 2015 Jun 11.

PMID:
26063501
29.

Comparing immunocompetent and immunodeficient mice as animal models for bone tissue engineering.

Zhang Y, Li X, Chihara T, Mizoguchi T, Hori A, Udagawa N, Nakamura H, Hasegawa H, Taguchi A, Shinohara A, Kagami H.

Oral Dis. 2015 Jul;21(5):583-92. doi: 10.1111/odi.12319. Epub 2015 Mar 30.

PMID:
25648203
30.

High-performance scaffolds on titanium surfaces: osteoblast differentiation and mineralization promoted by a globular fibrinogen layer through cell-autonomous BMP signaling.

Horasawa N, Yamashita T, Uehara S, Udagawa N.

Mater Sci Eng C Mater Biol Appl. 2015 Jan;46:86-96. doi: 10.1016/j.msec.2014.10.025. Epub 2014 Oct 13.

PMID:
25491963
31.

Roles of cathelicidins in inflammation and bone loss.

Nakamichi Y, Horibe K, Takahashi N, Udagawa N.

Odontology. 2014 Jul;102(2):137-46. doi: 10.1007/s10266-014-0167-0. Epub 2014 Jul 22. Review.

PMID:
25047111
32.

[Cytokine-mediated bone resorption].

Nakamura M, Uehara S, Nakamura H, Udagawa N.

Clin Calcium. 2014 Jun;24(6):837-44. doi: CliCa1406837844. Review. Japanese.

PMID:
24870834
33.

Noncanonical Wnt5a enhances Wnt/β-catenin signaling during osteoblastogenesis.

Okamoto M, Udagawa N, Uehara S, Maeda K, Yamashita T, Nakamichi Y, Kato H, Saito N, Minami Y, Takahashi N, Kobayashi Y.

Sci Rep. 2014 Mar 27;4:4493. doi: 10.1038/srep04493.

34.

Vitamin D endocrine system and osteoclasts.

Takahashi N, Udagawa N, Suda T.

Bonekey Rep. 2014 Feb 5;3:495. doi: 10.1038/bonekey.2013.229. eCollection 2014. Erratum in: Bonekey Rep. 2014;3:522. Udagawa, Naoyuki [corrected to Udagawa, Nobuyuki].

35.

[Osteoclast-mediated demineralization of biomineral].

Udagawa N, Koide M, Horibe K, Nakamura M.

Clin Calcium. 2014 Feb;24(2):215-23. doi: CliCa1402215223. Review. Japanese.

PMID:
24473354
36.

Arctigenin inhibits osteoclast differentiation and function by suppressing both calcineurin-dependent and osteoblastic cell-dependent NFATc1 pathways.

Yamashita T, Uehara S, Udagawa N, Li F, Kadota S, Esumi H, Kobayashi Y, Takahashi N.

PLoS One. 2014 Jan 17;9(1):e85878. doi: 10.1371/journal.pone.0085878. eCollection 2014.

37.

Roles of cathelicidin-related antimicrobial peptide in murine osteoclastogenesis.

Horibe K, Nakamichi Y, Uehara S, Nakamura M, Koide M, Kobayashi Y, Takahashi N, Udagawa N.

Immunology. 2013 Nov;140(3):344-51. doi: 10.1111/imm.12146.

38.

IL-34 and CSF-1: similarities and differences.

Nakamichi Y, Udagawa N, Takahashi N.

J Bone Miner Metab. 2013 Sep;31(5):486-95. doi: 10.1007/s00774-013-0476-3. Epub 2013 Jun 6. Review.

PMID:
23740288
39.

New roles of osteoblasts involved in osteoclast differentiation.

Yamashita T, Takahashi N, Udagawa N.

World J Orthop. 2012 Nov 18;3(11):175-81. doi: 10.5312/wjo.v3.i11.175.

40.

Stimulation of bone formation in cortical bone of mice treated with a receptor activator of nuclear factor-κB ligand (RANKL)-binding peptide that possesses osteoclastogenesis inhibitory activity.

Furuya Y, Inagaki A, Khan M, Mori K, Penninger JM, Nakamura M, Udagawa N, Aoki K, Ohya K, Uchida K, Yasuda H.

J Biol Chem. 2013 Feb 22;288(8):5562-71. doi: 10.1074/jbc.M112.426080. Epub 2013 Jan 14.

41.

Osteoprotegerin-deficient male mice as a model for severe alveolar bone loss: comparison with RANKL-overexpressing transgenic male mice.

Koide M, Kobayashi Y, Ninomiya T, Nakamura M, Yasuda H, Arai Y, Okahashi N, Yoshinari N, Takahashi N, Udagawa N.

Endocrinology. 2013 Feb;154(2):773-82. doi: 10.1210/en.2012-1928. Epub 2013 Jan 4.

PMID:
23291450
42.

Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice.

Nakamichi Y, Mizoguchi T, Arai A, Kobayashi Y, Sato M, Penninger JM, Yasuda H, Kato S, DeLuca HF, Suda T, Udagawa N, Takahashi N.

Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10006-11. doi: 10.1073/pnas.1207361109. Epub 2012 Jun 5.

43.

Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell-cell fusion.

Oikawa T, Oyama M, Kozuka-Hata H, Uehara S, Udagawa N, Saya H, Matsuo K.

J Cell Biol. 2012 May 14;197(4):553-68. doi: 10.1083/jcb.201111116.

44.

Fos plays an essential role in the upregulation of RANK expression in osteoclast precursors within the bone microenvironment.

Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, Penninger JM, Yamada K, Udagawa N, Takahashi N.

J Cell Sci. 2012 Jun 15;125(Pt 12):2910-7. doi: 10.1242/jcs.099986. Epub 2012 Mar 27.

45.

Carbon nanotubes induce bone calcification by bidirectional interaction with osteoblasts.

Shimizu M, Kobayashi Y, Mizoguchi T, Nakamura H, Kawahara I, Narita N, Usui Y, Aoki K, Hara K, Haniu H, Ogihara N, Ishigaki N, Nakamura K, Kato H, Kawakubo M, Dohi Y, Taruta S, Kim YA, Endo M, Ozawa H, Udagawa N, Takahashi N, Saito N.

Adv Mater. 2012 Apr 24;24(16):2176-85. doi: 10.1002/adma.201103832. Epub 2012 Mar 22.

PMID:
22447724
46.

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis.

Maeda K, Kobayashi Y, Udagawa N, Uehara S, Ishihara A, Mizoguchi T, Kikuchi Y, Takada I, Kato S, Kani S, Nishita M, Marumo K, Martin TJ, Minami Y, Takahashi N.

Nat Med. 2012 Feb 19;18(3):405-12. doi: 10.1038/nm.2653.

PMID:
22344299
47.

Tetracyclines convert the osteoclastic-differentiation pathway of progenitor cells to produce dendritic cell-like cells.

Kinugawa S, Koide M, Kobayashi Y, Mizoguchi T, Ninomiya T, Muto A, Kawahara I, Nakamura M, Yasuda H, Takahashi N, Udagawa N.

J Immunol. 2012 Feb 15;188(4):1772-81. doi: 10.4049/jimmunol.1101174. Epub 2012 Jan 16.

48.

Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone.

Harada S, Mizoguchi T, Kobayashi Y, Nakamichi Y, Takeda S, Sakai S, Takahashi F, Saito H, Yasuda H, Udagawa N, Suda T, Takahashi N.

J Bone Miner Res. 2012 Feb;27(2):461-73. doi: 10.1002/jbmr.555.

49.

Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices--a simple method for identifying polarized osteoclasts.

Nakayama T, Mizoguchi T, Uehara S, Yamashita T, Kawahara I, Kobayashi Y, Moriyama Y, Kurihara S, Sahara N, Ozawa H, Udagawa N, Takahashi N.

Bone. 2011 Dec;49(6):1331-9. doi: 10.1016/j.bone.2011.09.045. Epub 2011 Sep 29.

PMID:
21983021
50.

Regulation of osteoclast function.

Nakamura I, Takahashi N, Jimi E, Udagawa N, Suda T.

Mod Rheumatol. 2012 Apr;22(2):167-77. doi: 10.1007/s10165-011-0530-8. Epub 2011 Sep 28. Review.

PMID:
21953286

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