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Feasibility and utility of transbronchial cryobiopsy in primary lung cancer: Prospective, single arm study.

Kirita K, Udagawa H, Matsumoto S, Yoh K, Niho S, Goto K.

Ann Oncol. 2019 Apr;30 Suppl 2:ii76. doi: 10.1093/annonc/mdz065.009. No abstract available.


Percutaneous endoscopic gastrostomy with jejunal extension for a post-esophagectomy gastric conduit.

Urabe M, Koga S, Ohkura Y, Ueno M, Udagawa H.

Clin J Gastroenterol. 2020 Jan 24. doi: 10.1007/s12328-020-01096-6. [Epub ahead of print]


Characterization of the taste receptor-related G-protein, α-gustducin, in pancreatic β-cells.

Udagawa H, Hiramoto M, Kawaguchi M, Uebanso T, Ohara-Imaizumi M, Nammo T, Nishimura W, Yasuda K.

J Diabetes Investig. 2020 Jan 20. doi: 10.1111/jdi.13214. [Epub ahead of print]


Clinicopathologic Characteristics of Oligometastases from Esophageal Cancer and Long-Term Outcomes of Resection.

Ohkura Y, Shindoh J, Ueno M, Iizuka T, Udagawa H.

Ann Surg Oncol. 2020 Mar;27(3):651-659. doi: 10.1245/s10434-019-08175-0. Epub 2020 Jan 2.


Relationship between psychological distress and health-related quality of life at each point of the treatment of esophageal cancer.

Ohkura Y, Ichikura K, Shindoh J, Ueno M, Udagawa H, Matsushima E.

Esophagus. 2020 Jan 2. doi: 10.1007/s10388-019-00710-y. [Epub ahead of print]


Development of a model predicting the risk of eight major postoperative complications after esophagectomy based on 10 826 cases in the Japan National Clinical Database.

Ohkura Y, Miyata H, Konno H, Udagawa H, Ueno M, Shindoh J, Kumamaru H, Wakabayashi G, Gotoh M, Mori M.

J Surg Oncol. 2019 Dec 10. doi: 10.1002/jso.25800. [Epub ahead of print]


Diaphragmatic herniation following total gastrectomy: review of the long-term experience of a tertiary institution.

Urabe M, Haruta S, Ohkura Y, Yago A, Koga S, Tanaka T, Ueno M, Udagawa H.

Langenbecks Arch Surg. 2019 Dec;404(8):993-998. doi: 10.1007/s00423-019-01842-6. Epub 2019 Nov 19.


Anasarca, steatorrhea, and hypoalbuminemia 18 years after total gastrectomy: a case report.

Igata Y, Okubo S, Ohkura Y, Ueno M, Udagawa H.

Surg Case Rep. 2019 Oct 24;5(1):155. doi: 10.1186/s40792-019-0721-7.


Non-small cell lung cancer with loss of expression of the SWI/SNF complex is associated with aggressive clinicopathological features, PD-L1-positive status, and high tumor mutation burden.

Naito T, Udagawa H, Umemura S, Sakai T, Zenke Y, Kirita K, Matsumoto S, Yoh K, Niho S, Tsuboi M, Ishii G, Goto K.

Lung Cancer. 2019 Dec;138:35-42. doi: 10.1016/j.lungcan.2019.10.009. Epub 2019 Oct 13.


Validity of using immunohistochemistry to predict treatment outcome in patients with non-small cell lung cancer not otherwise specified.

Ota T, Kirita K, Matsuzawa R, Udagawa H, Matsumoto S, Yoh K, Niho S, Ishii G, Goto K.

J Cancer Res Clin Oncol. 2019 Oct;145(10):2495-2506. doi: 10.1007/s00432-019-03012-z. Epub 2019 Sep 7.


TAS6417/CLN-081 Is a Pan-Mutation-Selective EGFR Tyrosine Kinase Inhibitor with a Broad Spectrum of Preclinical Activity against Clinically Relevant EGFR Mutations.

Udagawa H, Hasako S, Ohashi A, Fujioka R, Hakozaki Y, Shibuya M, Abe N, Komori T, Haruma T, Terasaka M, Fujita R, Hashimoto A, Funabashi K, Yasuda H, Miyadera K, Goto K, Costa DB, Kobayashi SS.

Mol Cancer Res. 2019 Nov;17(11):2233-2243. doi: 10.1158/1541-7786.MCR-19-0419. Epub 2019 Aug 29.


Phase I safety and pharmacokinetics study of rovalpituzumab tesirine in Japanese patients with advanced, recurrent small cell lung cancer.

Udagawa H, Akamatsu H, Tanaka K, Takeda M, Kanda S, Kirita K, Teraoka S, Nakagawa K, Fujiwara Y, Yasuda I, Okubo S, Shintani M, Kosloski MP, Scripture C, Tamura T, Okamoto I.

Lung Cancer. 2019 Sep;135:145-150. doi: 10.1016/j.lungcan.2019.07.025. Epub 2019 Jul 24.


Secretion of high amounts of hepatocyte growth factor is a characteristic feature of cancer-associated fibroblasts with EGFR-TKI resistance-promoting phenotype: A study of 18 cases of cancer-associated fibroblasts.

Suzuki E, Yamazaki S, Naito T, Hashimoto H, Okubo S, Udagawa H, Goto K, Tsuboi M, Ochiai A, Ishii G.

Pathol Int. 2019 Aug;69(8):472-480. doi: 10.1111/pin.12838. Epub 2019 Jul 24.


Clinicopathological presentations and surgical outcomes of esophageal melanoma.

Urabe M, Haruta S, Ohkura Y, Inoshita N, Yago A, Koga S, Tanaka T, Ueno M, Udagawa H.

Asian Cardiovasc Thorac Ann. 2019 Sep;27(7):548-553. doi: 10.1177/0218492319866064. Epub 2019 Jul 18. No abstract available.


A Minimum Of 100 Tumor Cells in a Single Biopsy Sample Is Required to Assess Programmed Cell Death Ligand 1 Expression in Predicting Patient Response to Nivolumab Treatment in Nonsquamous Non-Small Cell Lung Carcinoma.

Naito T, Udagawa H, Sato J, Horinouchi H, Murakami S, Goto Y, Kanda S, Fujiwara Y, Yamamoto N, Zenke Y, Kirita K, Matsumoto S, Yoh K, Niho S, Motoi N, Ohe Y, Ishii G, Goto K.

J Thorac Oncol. 2019 Oct;14(10):1818-1827. doi: 10.1016/j.jtho.2019.06.019. Epub 2019 Jun 28.


A Strategy for Discovering Heterochiral Bioactive Peptides by Using the OB2n P Library and SPOTs Method.

Udagawa H, Yoneda TH, Masuda R, Koide T.

Chembiochem. 2019 Aug 16;20(16):2070-2073. doi: 10.1002/cbic.201900237. Epub 2019 Jul 15.


Comprehensive registry of esophageal cancer in Japan, 2012.

Tachimori Y, Ozawa S, Numasaki H, Ishihara R, Matsubara H, Muro K, Oyama T, Toh Y, Udagawa H, Uno T; Registration Committee for Esophageal Cancer of the Japan Esophageal Society.

Esophagus. 2019 Jul;16(3):221-245. doi: 10.1007/s10388-019-00674-z. Epub 2019 May 16. No abstract available.


Comparison of long-term outcomes between esophagectomy and chemoradiotherapy after endoscopic resection of submucosal esophageal squamous cell carcinoma.

Tanaka T, Ueno M, Iizuka T, Hoteya S, Haruta S, Udagawa H.

Dis Esophagus. 2019 Dec 31;32(12). pii: doz023. doi: 10.1093/dote/doz023.


Successful treatment with nivolumab for SMARCA4-deficient non-small cell lung carcinoma with a high tumor mutation burden: A case report.

Naito T, Umemura S, Nakamura H, Zenke Y, Udagawa H, Kirita K, Matsumoto S, Yoh K, Niho S, Motoi N, Aokage K, Tsuboi M, Ishii G, Goto K.

Thorac Cancer. 2019 May;10(5):1285-1288. doi: 10.1111/1759-7714.13070. Epub 2019 Apr 10.


Combined hepatocellular-cholangiocarcinoma with angiosarcomatoid change: A case report with immunohistochemical study.

Hakozaki M, Ito S, Fujii T, Kiya Y, Udagawa H, Fukayama M, Fukusato T.

Pathol Int. 2019 Feb;69(2):110-116. doi: 10.1111/pin.12755. Epub 2019 Jan 23.


Genetic profiling-based prognostic prediction of patients with advanced small-cell lung cancer in large scale analysis.

Udagawa H, Umemura S, Murakami I, Mimaki S, Makinoshima H, Ishii G, Miyoshi T, Kirita K, Matsumoto S, Yoh K, Niho S, Tsuchihara K, Goto K.

Lung Cancer. 2018 Dec;126:182-188. doi: 10.1016/j.lungcan.2018.11.014. Epub 2018 Nov 12.


Prognostic Factors and Appropriate Lymph Node Dissection in Salvage Esophagectomy for Locally Advanced T4 Esophageal Cancer.

Ohkura Y, Ueno M, Iizuka T, Udagawa H.

Ann Surg Oncol. 2019 Jan;26(1):209-216. doi: 10.1245/s10434-018-7074-5. Epub 2018 Nov 21.


Laparoscopic distal gastrectomy in a patient with gastric cancer complicated by eventration of the diaphragm: A case report.

Fujii T, Haruta S, Ohkura Y, Honda A, Kobayashi N, Tanaka T, Ueno M, Udagawa H.

Asian J Endosc Surg. 2019 Jul;12(3):318-321. doi: 10.1111/ases.12648. Epub 2018 Nov 8.


Metabolic Characterization of Antifolate Responsiveness and Non-responsiveness in Malignant Pleural Mesothelioma Cells.

Sato Y, Matsuda S, Maruyama A, Nakayama J, Miyashita T, Udagawa H, Umemura S, Yanagihara K, Ochiai A, Tomita M, Soga T, Tsuchihara K, Makinoshima H.

Front Pharmacol. 2018 Oct 12;9:1129. doi: 10.3389/fphar.2018.01129. eCollection 2018.


Genome-wide profiling of histone H3K27 acetylation featured fatty acid signalling in pancreatic beta cells in diet-induced obesity in mice.

Nammo T, Udagawa H, Funahashi N, Kawaguchi M, Uebanso T, Hiramoto M, Nishimura W, Yasuda K.

Diabetologia. 2018 Dec;61(12):2608-2620. doi: 10.1007/s00125-018-4735-7. Epub 2018 Oct 3.


Impact of prophylactic cranial irradiation on pattern of brain metastases as a first recurrence site for limited-disease small-cell lung cancer.

Nakamura M, Onozawa M, Motegi A, Hojo H, Zenda S, Nakamura N, Udagawa H, Kirita K, Matsumoto S, Umemura S, Yoh K, Niho S, Goto K, Akimoto T.

J Radiat Res. 2018 Nov 1;59(6):767-773. doi: 10.1093/jrr/rry066.


Identifying the inserted locus of randomly integrated expression plasmids by whole-genome sequencing of Aspergillus strains.

Takeda AK, Udagawa H, Uemura Y, Takagi S.

Biosci Biotechnol Biochem. 2018 Nov;82(11):1880-1888. doi: 10.1080/09168451.2018.1506312. Epub 2018 Aug 10.


Risk Factors for Postoperative Chylothorax After Radical Subtotal Esophagectomy.

Ohkura Y, Ueno M, Shindoh J, Iizuka T, Ka H, Udagawa H.

Ann Surg Oncol. 2018 Sep;25(9):2739-2746. doi: 10.1245/s10434-018-6640-1. Epub 2018 Jul 11.


Correction to: Comprehensive Registry of Esophageal Cancer in Japan, 2011.

Tachimori Y, Ozawa S, Numasaki H, Ishihara R, Matsubara H, Muro K, Oyama T, Toh Y, Udagawa H, Uno T; Registration Committee for Esophageal Cancer of the Japan Esophageal Society.

Esophagus. 2018 Oct;15(4):304-305. doi: 10.1007/s10388-018-0624-x.


Comprehensive Registry of Esophageal Cancer in Japan, 2011.

Tachimori Y, Ozawa S, Numasaki H, Ishihara R, Matsubara H, Muro K, Oyama T, Toh Y, Udagawa H, Uno T; Registration Committee for Esophageal Cancer of the Japan Esophageal Society.

Esophagus. 2018 Jul;15(3):127-152. doi: 10.1007/s10388-018-0614-z. Epub 2018 Apr 18. No abstract available. Erratum in: Esophagus. 2018 Jun 12;:.


Surgical outcomes in gastroenterological surgery in Japan: Report of National Clinical database 2011-2016.

Kakeji Y, Takahashi A, Udagawa H, Unno M, Endo I, Kunisaki C, Taketomi A, Tangoku A, Masaki T, Marubashi S, Yoshida K, Gotoh M, Konno H, Miyata H, Seto Y; National Clinical Database.

Ann Gastroenterol Surg. 2017 Nov 23;2(1):37-54. doi: 10.1002/ags3.12052. eCollection 2018 Jan.


Patient-oriented optimal depth of conscious sedation using midazolam during flexible bronchoscopy: A prospective open-labeled single-arm trial.

Takeda Y, Udagawa H, Nakamichi S, Yoneshima Y, Iikura M, Hirano S, Naka G, Sugiyama H.

Respir Investig. 2018 Jul;56(4):349-355. doi: 10.1016/j.resinv.2018.03.007. Epub 2018 May 6.


Comparison of two major staging systems of esophageal cancer-toward more practical common scale for tumor staging.

Udagawa H, Ueno M.

Ann Transl Med. 2018 Feb;6(4):76. doi: 10.21037/atm.2018.01.27. Review.


Mutation of a Nicotiana tabacum L. eukaryotic translation-initiation factor gene reduces susceptibility to a resistance-breaking strain of Potato virus Y.

Takakura Y, Udagawa H, Shinjo A, Koga K.

Mol Plant Pathol. 2018 Sep;19(9):2124-2133. doi: 10.1111/mpp.12686. Epub 2018 Jul 17.


Efficacy of Endoscopic Management for Early Remnant Gastric Cancer: Is Completion Gastrectomy Truly Necessary in Cases with Marginally Noncurative Histopathologic Features?

Fukui Y, Shindoh J, Inoshita N, Mizuno A, Haruta S, Udagawa H, Hoteya S, Tsunoda S, Miyamoto S, Ozawa R, Niwa H, Sakai Y, Shinohara H.

Ann Surg Oncol. 2018 Jun;25(6):1608-1615. doi: 10.1245/s10434-018-6407-8. Epub 2018 Apr 9.


Comparison of Outcome of Esophagectomy Versus Nonsurgical Treatment for Resectable Esophageal Cancer with Clinical Complete Response to Neoadjuvant Therapy.

Ohkura Y, Shindoh J, Ueno M, Iizuka T, Udagawa H.

Ann Surg Oncol. 2018 Aug;25(8):2428-2433. doi: 10.1245/s10434-018-6437-2. Epub 2018 Mar 21.


Metabolic Determinants of Sensitivity to Phosphatidylinositol 3-Kinase Pathway Inhibitor in Small-Cell Lung Carcinoma.

Makinoshima H, Umemura S, Suzuki A, Nakanishi H, Maruyama A, Udagawa H, Mimaki S, Matsumoto S, Niho S, Ishii G, Tsuboi M, Ochiai A, Esumi H, Sasaki T, Goto K, Tsuchihara K.

Cancer Res. 2018 May 1;78(9):2179-2190. doi: 10.1158/0008-5472.CAN-17-2109. Epub 2018 Feb 28.


Salvage chemoradiotherapy with cisplatin and vinorelbine for postoperative locoregional recurrence of non-small cell lung cancer.

Hisakane K, Yoh K, Nakamura N, Udagawa H, Kirita K, Umemura S, Matsumoto S, Niho S, Akimoto T, Tsuboi M, Goto K.

Medicine (Baltimore). 2017 Nov;96(47):e8635. doi: 10.1097/MD.0000000000008635.


Effectiveness of etilefrine regimen for chylothorax after esophagectomy with thoracic duct resection.

Ohkura Y, Ueno M, Iizuka T, Udagawa H.

Esophagus. 2018;15(1):33-38. doi: 10.1007/s10388-017-0592-6. Epub 2017 Sep 14.


A case of superficial esophageal cancer invading into the submucosa following ductal involvement with microinvasion.

Suzuki Y, Iizuka T, Inoshita N, Kikuchi D, Hoteya S, Udagawa H.

Clin J Gastroenterol. 2018 Apr;11(2):123-126. doi: 10.1007/s12328-017-0810-8. Epub 2017 Dec 20.


A new postoperative pain management (intravenous acetaminophen: Acelio®) leads to enhanced recovery after esophagectomy: a propensity score-matched analysis.

Ohkura Y, Shindoh J, Ueno M, Iizuka T, Haruta S, Udagawa H.

Surg Today. 2018 May;48(5):502-509. doi: 10.1007/s00595-017-1616-5. Epub 2017 Dec 12.


A type 2 diabetes-associated SNP in KCNQ1 (rs163184) modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a, potentially affecting CDKN1C expression.

Hiramoto M, Udagawa H, Ishibashi N, Takahashi E, Kaburagi Y, Miyazawa K, Funahashi N, Nammo T, Yasuda K.

Int J Mol Med. 2018 Feb;41(2):717-728. doi: 10.3892/ijmm.2017.3273. Epub 2017 Nov 20.


Serial pseudoprogression of metastatic malignant melanoma in a patient treated with nivolumab: a case report.

Ozaki Y, Shindoh J, Miura Y, Nakajima H, Oki R, Uchiyama M, Masuda J, Kinowaki K, Kondoh C, Tanabe Y, Tanaka T, Haruta S, Ueno M, Kitano S, Fujii T, Udagawa H, Takano T.

BMC Cancer. 2017 Nov 21;17(1):778. doi: 10.1186/s12885-017-3785-4.


Association between immune-related adverse events and efficacy of nivolumab in advanced non-small cell lung cancer.

Usui Y, Udagawa H, Kirita K, Umemura S, Matsumoto S, Yoh K, Niho S, Goto K.

Ann Oncol. 2017 Oct;28 Suppl 9:ix86. doi: 10.1093/annonc/mdx697.053. No abstract available.


Impact of laparoscopy on the prevention of pulmonary complications after thoracoscopic esophagectomy using data from JCOG0502: a prospective multicenter study.

Nozaki I, Mizusawa J, Kato K, Igaki H, Ito Y, Daiko H, Yano M, Udagawa H, Nakagawa S, Takagi M, Kitagawa Y.

Surg Endosc. 2018 Feb;32(2):651-659. doi: 10.1007/s00464-017-5716-5. Epub 2017 Aug 4.


Comprehensive Registry of Esophageal Cancer in Japan, 2010.

Tachimori Y, Ozawa S, Numasaki H, Ishihara R, Matsubara H, Muro K, Oyama T, Toh Y, Udagawa H, Uno T; Registration Committee for Esophageal Cancer of the Japan Esophageal Society.

Esophagus. 2017;14(3):189-214. doi: 10.1007/s10388-017-0578-4. Epub 2017 May 19. No abstract available.


Efficacy of prophylactic splenectomy for proximal advanced gastric cancer invading greater curvature.

Ohkura Y, Haruta S, Shindoh J, Tanaka T, Ueno M, Udagawa H.

World J Surg Oncol. 2017 May 25;15(1):106. doi: 10.1186/s12957-017-1173-9.


CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors.

Ishibashi M, Neri S, Hashimoto H, Miyashita T, Yoshida T, Nakamura Y, Udagawa H, Kirita K, Matsumoto S, Umemura S, Yoh K, Niho S, Tsuboi M, Masutomi K, Goto K, Ochiai A, Ishii G.

Sci Rep. 2017 Apr 21;7:46662. doi: 10.1038/srep46662.

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