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Intratumoral heterogeneity of glutaminase and lactate dehydrogenase A protein expression in colorectal cancer.

Mizuno Y, Hattori K, Taniguchi K, Tanaka K, Uchiyama K, Hirose Y.

Oncol Lett. 2020 Apr;19(4):2934-2942. doi: 10.3892/ol.2020.11390. Epub 2020 Feb 13.


Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis.

Fujii K, Nakajo K, Egashira Y, Yamamoto Y, Kitada K, Taniguchi K, Kawai M, Tomiyama H, Kawakami K, Uchiyama K, Ono F.

Cell Rep. 2020 Mar 3;30(9):2879-2888.e3. doi: 10.1016/j.celrep.2020.02.024.


A portable pneumatic compression device to prevent venous thromboembolism in orthopedic patients with the highest risks of both venous thrombosis and bleeding: A case series study.

Takahashi Y, Takahira N, Shibuya M, Uchiyama K, Fukushima K, Iwase D, Kawamura T, Miyagi M, Higashiyama R, Moriya M, Sakai K, Tsuda K, Sakamoto M, Akamine A, Takaso M.

J Orthop Surg (Hong Kong). 2020 Jan-Apr;28(1):2309499020905711. doi: 10.1177/2309499020905711.


Generation of Schubert polynomial series via nanometre-scale photoisomerization in photochromic single crystal and double-probe optical near-field measurements.

Uchiyama K, Suzui H, Nakagomi R, Saigo H, Uchida K, Naruse M, Hori H.

Sci Rep. 2020 Feb 17;10(1):2710. doi: 10.1038/s41598-020-59603-1.


Surgical treatment of gastric venous congestion in association with extended resection of pancreas: a case report.

Kagota S, Shimizu T, Taniguchi K, Tomioka A, Inoue Y, Komeda K, Asakuma M, Lee SW, Hirokawa F, Uchiyama K.

BMC Surg. 2020 Feb 10;20(1):28. doi: 10.1186/s12893-020-0692-4.


The maximal gait speed is a simple and useful prognostic indicator for functional recovery after total hip arthroplasty.

Shibuya M, Nanri Y, Kamiya K, Fukushima K, Uchiyama K, Takahira N, Takaso M, Fukuda M, Matsunaga A.

BMC Musculoskelet Disord. 2020 Feb 7;21(1):84. doi: 10.1186/s12891-020-3093-z.


Effects of exercise on residual renal function in patients undergoing peritoneal dialysis: A post-hoc analysis of a randomized controlled trial.

Uchiyama K, Washida N, Morimoto K, Muraoka K, Nakayama T, Adachi K, Kasai T, Miyashita K, Wakino S, Itoh H.

Ther Apher Dial. 2020 Jan 30. doi: 10.1111/1744-9987.13481. [Epub ahead of print]


Promotion of wound healing by acetate in murine colonic epithelial cell via c-Jun N-terminal kinase activation.

Nakano T, Uchiyama K, Ushiroda C, Kashiwagi S, Toyokawa Y, Mizushima K, Inoue K, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Handa O, Ishikawa T, Takagi T, Konishi H, Naito Y, Itoh Y.

J Gastroenterol Hepatol. 2020 Jan 21. doi: 10.1111/jgh.14987. [Epub ahead of print]


FADS2 and ELOVL6 mutation frequencies in Japanese Crohn's disease patients.

Motoi Y, Ito Z, Suzuki S, Takami S, Matsuo K, Sato M, Ota Y, Tsuruta M, Kojima M, Noguchi M, Uchiyama K, Kubota T.

Drug Discov Ther. 2019;13(6):354-359. doi: 10.5582/ddt.2019.01081.


Impact of advanced radiotherapy techniques and dose intensification on toxicity of salvage radiotherapy after radical prostatectomy.

Tomita N, Uchiyama K, Mizuno T, Imai M, Sugie C, Ayakawa S, Niwa M, Matsui T, Otsuka S, Manabe Y, Nomura K, Kondo T, Kosaki K, Miyakawa A, Miyamoto A, Takemoto S, Kitagawa Y, Yasui T, Shibamoto Y.

Sci Rep. 2020 Jan 10;10(1):114. doi: 10.1038/s41598-019-57056-9.


Efficacy and safety of endoscopic submucosal dissection using a scissors-type knife with prophylactic over-the-scope clip closure for superficial non-ampullary duodenal epithelial tumors.

Dohi O, Yoshida N, Naito Y, Yoshida T, Ishida T, Azuma Y, Kitae H, Matsumura S, Takayama S, Ogita K, Mizuno N, Nakano T, Majima A, Hirose R, Inoue K, Kamada K, Uchiyama K, Takagi T, Ishikawa T, Konishi H, Morinaga Y, Kishimoto M, Itoh Y.

Dig Endosc. 2019 Dec 27. doi: 10.1111/den.13618. [Epub ahead of print]


The Relationship Between the Number of Ports and Surgical Outcomes in Laparoscopic Hepatectomy.

Inoue Y, Kitada K, Fujii K, Kagota S, Tomioka A, Yamaguchi T, Yokohama K, Ohama H, Hamamoto H, Ishii M, Osumi W, Tsuchimoto Y, Terazawa T, Ogura T, Masubuchi S, Yamamoto M, Imoto A, Asai A, Komeda K, Fukunishi S, Hirokawa F, Goto M, Tanaka K, Okuda J, Higuchi K, Uchiyama K.

Surg Laparosc Endosc Percutan Tech. 2020 Feb;30(1):85-90. doi: 10.1097/SLE.0000000000000750.


An In Vivo Mouse Model of Pelvic Recurrence of Human Colorectal Cancer.

Yamamoto M, Taniguchi K, Masubuchi S, Tominaga T, Inomata Y, Miyamoto A, Ishizuka TA, Murakami T, Osumi W, Hamamoto H, Tanaka K, Okuda J, Uchiyama K.

Sci Rep. 2019 Dec 23;9(1):19630. doi: 10.1038/s41598-019-56152-0.


Diagnostic Ability of Magnifying Blue Light Imaging with a Light Emitting Diode Light Source for Early Gastric Cancer: A Prospective Comparative Study.

Takayama S, Dohi O, Naito Y, Azuma Y, Ishida T, Kitae H, Matsumura S, Ogita K, Mizuno N, Terasaki K, Nakano T, Ueda T, Morinaga Y, Hirose R, Inoue K, Yoshida N, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Handa O, Kishimoto M, Konishi H, Itoh Y.

Digestion. 2019 Dec 12:1-10. doi: 10.1159/000505018. [Epub ahead of print]


Zinc deficiency activates IL-23/Th17 axis to aggravate experimental colitis in mice.

Higashimura Y, Takagi T, Naito Y, Uchiyama K, Mizushima K, Tanaka M, Hamaguchi M, Itoh Y.

J Crohns Colitis. 2019 Nov 30. pii: jjz193. doi: 10.1093/ecco-jcc/jjz193. [Epub ahead of print]


Effects of Guidelines for Gastroenterological Endoscopy in Patients Undergoing Antithrombotic Treatment on Postoperative Bleeding after Endoscopic Submucosal Dissection for Early Gastric Cancer: A Propensity Score-Matching Analysis.

Terasaki K, Dohi O, Naito Y, Azuma Y, Ishida T, Kitae H, Matsumura S, Ogita K, Takayama S, Mizuno N, Nakano T, Iwai N, Ueda T, Hirose R, Inoue K, Yoshida N, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Itoh Y.

Digestion. 2019 Nov 26:1-9. doi: 10.1159/000504597. [Epub ahead of print]


Concentrating Single Cells in Picoliter Droplets for Phospholipid Profiling on a Microfluidic System.

Zhang W, Li N, Lin L, Huang Q, Uchiyama K, Lin JM.

Small. 2020 Mar;16(9):e1903402. doi: 10.1002/smll.201903402. Epub 2019 Nov 26.


Functional Evaluation for Various Methods of Gastrectomy and Reconstruction for Gastric Cancer.

Nomura E, Kayano H, Machida T, Uda S, Nabeshima K, Nakamura K, Lee SW, Kawai M, Izumi H, Yamamoto S, Mukai M, Uchiyama K.

Tokai J Exp Clin Med. 2019 Dec 20;44(4):108-112.


Higher Levels of Streptococcus in Upper Gastrointestinal Mucosa Associated with Symptoms in Patients with Functional Dyspepsia.

Fukui A, Takagi T, Naito Y, Inoue R, Kashiwagi S, Mizushima K, Inada Y, Inoue K, Harusato A, Dohi O, Okayama T, Katada K, Kamada K, Uchiyama K, Ishikawa T, Handa O, Itoh Y, Nakagawa M.

Digestion. 2020;101(1):38-45. doi: 10.1159/000504090. Epub 2019 Nov 21.


High-Fat Diet Causes Constipation in Mice via Decreasing Colonic Mucus.

Mukai R, Handa O, Naito Y, Takayama S, Suyama Y, Ushiroda C, Majima A, Hirai Y, Mizushima K, Okayama T, Katada K, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Itoh Y.

Dig Dis Sci. 2019 Nov 14. doi: 10.1007/s10620-019-05954-3. [Epub ahead of print]


The N-Terminal Polybasic Region of Prion Protein Is Crucial in Prion Pathogenesis Independently of the Octapeptide Repeat Region.

Das NR, Miyata H, Hara H, Chida J, Uchiyama K, Masujin K, Watanabe H, Kondoh G, Sakaguchi S.

Mol Neurobiol. 2020 Feb;57(2):1203-1216. doi: 10.1007/s12035-019-01804-5. Epub 2019 Nov 9.


15-Deoxy-Δ12,14-prostaglandin J2 ameliorates dextran sulfate sodium-induced colitis in mice through heme oxygenase-1 induction.

Takagi T, Naito Y, Mizushima K, Hirai Y, Kamada K, Uchiyama K, Handa O, Ishikawa T, Itoh Y.

Arch Biochem Biophys. 2019 Nov 30;677:108183. doi: 10.1016/ Epub 2019 Nov 5.


Initial pulmonary metastasis after pancreatectomy for pancreatic ductal adenocarcinoma.

Shimizu T, Taniguchi K, Asakuma M, Komeda K, Inoue Y, Lee SW, Hirokawa F, Uchiyama K.

Surg Today. 2020 Apr;50(4):413-418. doi: 10.1007/s00595-019-01902-w. Epub 2019 Oct 31.


Early administration of pegfilgrastim for esophageal cancer treated with docetaxel, cisplatin, and fluorouracil: A phase II study.

Ishikawa T, Yasuda T, Okayama T, Dohi O, Yoshida N, Kamada K, Uchiyama K, Takagi T, Konishi H, Shiozaki A, Fujiwara H, Konishi H, Naito Y, Teramukai S, Itoh Y.

Cancer Sci. 2019 Dec;110(12):3754-3760. doi: 10.1111/cas.14218.


Male sex and anterior wall tumor location as risk factors for urinary dysfunction after laparoscopic rectal surgery.

Hamamoto H, Yamamoto M, Masubuchi S, Ishii M, Osumi W, Tanaka K, Okuda J, Uchiyama K.

Surg Endosc. 2019 Oct 11. doi: 10.1007/s00464-019-07186-y. [Epub ahead of print]


Genotypes and allele frequencies of buried SNPs in a bovine single-nucleotide polymorphism array in Japanese Black cattle.

Sasaki S, Muraki E, Inoue Y, Suezawa R, Nikadori H, Yoshida Y, Nariai S, Hideshima R, Moriwaki S, Nakashima R, Uchiyama K, Yoshinari K, Takeda M, Kojima T.

Anim Sci J. 2019 Dec;90(12):1503-1509. doi: 10.1111/asj.13293. Epub 2019 Oct 10.


The Management of Recurrence within Six Months after Hepatic Resection for Colorectal Liver Metastasis.

Inoue Y, Fujii K, Kagota S, Tomioka A, Yamaguchi T, Ohama H, Hamamoto H, Ishii M, Osumi W, Tsuchimoto Y, Terazawa T, Ogura T, Masubuchi S, Yamamoto M, Imoto A, Asai A, Komeda K, Fukunishi S, Hirokawa F, Goto M, Tanaka K, Okuda J, Higuchi K, Uchiyama K.

Dig Surg. 2019 Oct 9:1-10. doi: 10.1159/000503420. [Epub ahead of print]


α-Aminoisobutyric Acid-Containing Amphipathic Helical Peptide-Cyclic RGD Conjugation as a Potential Drug Delivery System for MicroRNA Replacement Therapy in Vitro.

Taniguchi K, Wada SI, Ito Y, Hayashi J, Inomata Y, Lee SW, Tanaka T, Komura K, Akao Y, Urata H, Uchiyama K.

Mol Pharm. 2019 Nov 4;16(11):4542-4550. doi: 10.1021/acs.molpharmaceut.9b00680. Epub 2019 Oct 25.


Local recurrence and its risk factors after cold snare polypectomy of colorectal polyps.

Murakami T, Yoshida N, Yasuda R, Hirose R, Inoue K, Dohi O, Kamada K, Uchiyama K, Konishi H, Naito Y, Morinaga Y, Kishimoto M, Konishi E, Ogiso K, Inada Y, Itoh Y.

Surg Endosc. 2019 Sep 3. doi: 10.1007/s00464-019-07072-7. [Epub ahead of print]


Current status of eye disorders caused by docetaxel administration every 3 weeks: A case-control study in Japanese patients.

Noguchi Y, Kawashima Y, Maruyama M, Kawara H, Tokuyama Y, Uchiyama K, Shimizu Y.

J Oncol Pharm Pract. 2019 Aug 25:1078155219868761. doi: 10.1177/1078155219868761. [Epub ahead of print]


Environment-dependent introgression from Quercus dentata to a coastal ecotype of Quercus mongolica var. crispula in northern Japan.

Nagamitsu T, Uchiyama K, Izuno A, Shimizu H, Nakanishi A.

New Phytol. 2019 Aug 19. doi: 10.1111/nph.16131. [Epub ahead of print]


Green tea polyphenol (epigallocatechin-3-gallate) improves gut dysbiosis and serum bile acids dysregulation in high-fat diet-fed mice.

Ushiroda C, Naito Y, Takagi T, Uchiyama K, Mizushima K, Higashimura Y, Yasukawa Z, Okubo T, Inoue R, Honda A, Matsuzaki Y, Itoh Y.

J Clin Biochem Nutr. 2019 Jul;65(1):34-46. doi: 10.3164/jcbn.18-116. Epub 2019 Apr 6.


Delta-like 3 localizes to neuroendocrine cells and plays a pivotal role in gastrointestinal neuroendocrine malignancy.

Matsuo K, Taniguchi K, Hamamoto H, Ito Y, Futaki S, Inomata Y, Shima T, Asakuma M, Lee SW, Tanaka K, Okuda J, Kondo Y, Uchiyama K.

Cancer Sci. 2019 Oct;110(10):3122-3131. doi: 10.1111/cas.14157. Epub 2019 Aug 14.


Clinical silence of pulmonary lymphoepithelioma-like carcinoma with subcutaneous metastasis: a case report.

Shima T, Taniguchi K, Kobayashi Y, Kakimoto S, Fujio N, Uchiyama K.

World J Surg Oncol. 2019 Jul 24;17(1):128. doi: 10.1186/s12957-019-1671-z.


Laparoscopic Repeat Hepatic Resection for the Management of Liver Tumors.

Inoue Y, Fujii K, Ishii M, Kagota S, Tomioka A, Hamamoto H, Osumi W, Tsuchimoto Y, Terasawa T, Ogura T, Masubuchi S, Yamamoto M, Imoto A, Asai A, Komeda K, Fukunishi S, Hirokawa F, Goto M, Tanaka K, Okuda J, Higuchi K, Uchiyama K.

J Gastrointest Surg. 2019 Nov;23(11):2314-2321. doi: 10.1007/s11605-019-04276-z. Epub 2019 Jul 16.


Linked color imaging identifies important risk factors associated with gastric cancer after successful eradication of Helicobacter pylori.

Majima A, Dohi O, Takayama S, Hirose R, Inoue K, Yoshida N, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Handa O, Konishi H, Naito Y, Itoh Y.

Gastrointest Endosc. 2019 Nov;90(5):763-769. doi: 10.1016/j.gie.2019.06.043. Epub 2019 Jul 9.


Duodenal obstruction due to chronic pancreatitis of the pancreas tail treated by surgical intervention: A case report.

Tomioka A, Shimizu T, Asakuma M, Inoue Y, Taniguchi K, Hirokawa F, Hayashi M, Uchiyama K.

Medicine (Baltimore). 2019 Jul;98(27):e15856. doi: 10.1097/MD.0000000000015856.


Endoscopic Evaluation of Neoadjuvant Chemotherapeutic Efficacy in Gastric Cancer before Gastrectomy Might be as Useful as Histological Assessment after Gastrectomy.

Sugawara N, Ota K, Terazawa T, Tanaka R, Akutagawa H, Yamaguchi T, Imai Y, Harada S, Kojima Y, Tashiro K, Kii T, Lee SW, Kawai M, Egashira Y, Goto M, Uchiyama K, Hirose Y, Takeuchi T, Higuchi K.

Digestion. 2019 Jun 28:1-7. doi: 10.1159/000500907. [Epub ahead of print]


Acute Interstitial Nephritis With Karyomegalic Epithelial Cells After Nivolumab Treatment-Two Case Reports.

Ryuzaki M, Tokuyama H, Uchiyama K, Nakaya H, Hasegawa K, Miyashita K, Konishi K, Hashiguchi A, Wakino S, Itoh H.

Clin Med Insights Case Rep. 2019 Jun 13;12:1179547619853647. doi: 10.1177/1179547619853647. eCollection 2019.


Long-term outcomes of Wagner self-locking stem with bone allograft for Paprosky type II and III bone defects in revision total hip arthroplasty: A mean 15.7-year follow-up.

Zang J, Uchiyama K, Moriya M, Fukushima K, Takahira N, Takaso M.

J Orthop Surg (Hong Kong). 2019 May-Aug;27(2):2309499019854156. doi: 10.1177/2309499019854156.


Uremic encephalopathy in patients undergoing assisted peritoneal dialysis: a case series and literature review.

Yanai A, Uchiyama K, Ishibashi Y.

CEN Case Rep. 2019 Nov;8(4):271-279. doi: 10.1007/s13730-019-00406-3. Epub 2019 Jun 8.


Clinical significance of soluble forms of immune checkpoint molecules in advanced esophageal cancer.

Yoshida J, Ishikawa T, Doi T, Ota T, Yasuda T, Okayama T, Sakamoto N, Inoue K, Dohi O, Yoshida N, Kamada K, Uchiyama K, Takagi T, Konishi H, Naito Y, Itoh Y.

Med Oncol. 2019 May 27;36(7):60. doi: 10.1007/s12032-019-1285-x.


Influence of lysine residue in amphipathic helical peptides on targeted delivery of RNA into cancer cells.

Wada SI, Taniguchi K, Hamazaki H, Yamada A, Hayashi J, Uchiyama K, Urata H.

Bioorg Med Chem Lett. 2019 Aug 1;29(15):1934-1937. doi: 10.1016/j.bmcl.2019.05.044. Epub 2019 May 21.


Blastomere movement post first cell division correlates with embryonic compaction and subsequent blastocyst formation.

Ohata K, Ezoe K, Miki T, Morita H, Tsuchiya R, Kaneko S, Okimura T, Uchiyama K, Yabuuchi A, Kobayashi T, Montag M, Kato K.

Reprod Biol Endocrinol. 2019 May 15;17(1):44. doi: 10.1186/s12958-019-0488-5.


Diffusion-Weighted Magnetic Resonance Imaging and 18-Fluorodeoxglucose Positron Emission Tomography With Computed Tomography for Evaluating Malignancy of Branch Duct and Mixed Type Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Hayashi M, Mikata R, Horikoshi T, Senoo J, Kusakabe Y, Ohyama H, Yasui S, Uchida Y, Uchiyama K, Kishimoto T, Yoshitomi H, Ohtsuka M, Tsuyuguchi T, Kato N.

Pancreas. 2019 May/Jun;48(5):e43-e45. doi: 10.1097/MPA.0000000000001316. No abstract available.


Scanning RNA-Seq and RAD-Seq approach to develop SNP markers closely linked to MALE STERILITY 1 (MS1) in Cryptomeria japonica D. Don.

Ueno S, Uchiyama K, Moriguchi Y, Ujino-Ihara T, Matsumoto A, Wei FJ, Saito M, Higuchi Y, Futamura N, Kanamori H, Katayose Y, Tsumura Y.

Breed Sci. 2019 Mar;69(1):19-29. doi: 10.1270/jsbbs.17149. Epub 2019 Feb 15.


Selective Fabrication of Nanowires with High Aspect Ratios Using a Diffusion Mixing Reaction System for Applications in Temperature Sensing.

Lin H, Mao S, Zeng H, Zhang Y, Kawaguchi M, Tanaka Y, Lin JM, Uchiyama K.

Anal Chem. 2019 Jun 4;91(11):7346-7352. doi: 10.1021/acs.analchem.9b01122. Epub 2019 May 22.


Laparoscopic liver resection for patients with cardiac disease.

Inoue Y, Kagota S, Tsuchimoto Y, Ogura T, Asai A, Fukunishi S, Higuchi K, Uchiyama K.

Contemp Oncol (Pozn). 2019;23(1):37-42. doi: 10.5114/wo.2019.84109. Epub 2019 Apr 5.


Computational modeling of pancreatic cancer patients receiving FOLFIRINOX and gemcitabine-based therapies identifies optimum intervention strategies.

Yamamoto KN, Nakamura A, Liu LL, Stein S, Tramontano AC, Kartoun U, Shimizu T, Inoue Y, Asakuma M, Haeno H, Kong CY, Uchiyama K, Gonen M, Hur C, Michor F.

PLoS One. 2019 Apr 26;14(4):e0215409. doi: 10.1371/journal.pone.0215409. eCollection 2019.


Long-term peritoneal dialysis followed by kidney transplantation for Takayasu arteritis: a case report.

Yanai A, Uchiyama K, Ishibashi Y.

BMC Nephrol. 2019 Apr 18;20(1):131. doi: 10.1186/s12882-019-1302-5.

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