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Items: 1 to 50 of 60

1.

Cellular reactions to long-term volatile organic compound (VOC) exposures.

Gostner JM, Zeisler J, Alam MT, Gruber P, Fuchs D, Becker K, Neubert K, Kleinhappl M, Martini S, Überall F.

Sci Rep. 2016 Dec 1;6:37842. doi: 10.1038/srep37842.

2.

Quantitative Ethylene Measurements with MOx Chemiresistive Sensors at Different Relative Air Humidities.

Krivec M, Mc Gunnigle G, Abram A, Maier D, Waldner R, Gostner JM, Überall F, Leitner R.

Sensors (Basel). 2015 Nov 6;15(11):28088-98. doi: 10.3390/s151128088.

3.

Bisphenol A suppresses Th1-type immune response in human peripheral blood mononuclear cells in vitro.

Gostner JM, Raggl E, Becker K, Überall F, Schennach H, Pease JE, Fuchs D.

Immunol Lett. 2015 Dec;168(2):285-92. doi: 10.1016/j.imlet.2015.10.006. Epub 2015 Oct 22.

4.

The potential of targeting indoleamine 2,3-dioxygenase for cancer treatment.

Gostner JM, Becker K, Überall F, Fuchs D.

Expert Opin Ther Targets. 2015 May;19(5):605-15. doi: 10.1517/14728222.2014.995092. Epub 2015 Feb 15. Review.

PMID:
25684107
5.

Lavender oil suppresses indoleamine 2,3-dioxygenase activity in human PBMC.

Gostner JM, Ganzera M, Becker K, Geisler S, Schroecksnadel S, Überall F, Schennach H, Fuchs D.

BMC Complement Altern Med. 2014 Dec 16;14:503. doi: 10.1186/1472-6882-14-503.

6.

Comparison of in vitro tests for antioxidant and immunomodulatory capacities of compounds.

Becker K, Schroecksnadel S, Gostner J, Zaknun C, Schennach H, Uberall F, Fuchs D.

Phytomedicine. 2014 Jan 15;21(2):164-71. doi: 10.1016/j.phymed.2013.08.008. Epub 2013 Sep 14. Review.

PMID:
24041614
7.

[New approaches to elucidate the activities of botanical multi-component mixtures].

Gostner JM, Gruber P, Becker K, Naschberger M, Uberall F.

Forsch Komplementmed. 2013;20 Suppl 2:41-4. doi: 10.1159/000351739. Epub 2013 Jun 21. German.

8.

Pathway-focused bioassays and transcriptome analysis contribute to a better activity monitoring of complex herbal remedies.

Klein A, Wrulich OA, Jenny M, Gruber P, Becker K, Fuchs D, Gostner JM, Uberall F.

BMC Genomics. 2013 Feb 27;14:133. doi: 10.1186/1471-2164-14-133.

9.

Protein kinase C overexpression does not enhance immune-stimulatory surface markers of vaccinia-infected dendritic cells and DC cell lines.

Huemer HP, Geiger M, Posch W, Krumböck N, Fresser F, Wilflingseder D, Uberall F.

Immunol Invest. 2013;42(2):164-77. doi: 10.3109/08820139.2012.750340.

PMID:
23323525
10.

Antimalarial drug chloroquine counteracts activation of indoleamine (2,3)-dioxygenase activity in human PBMC.

Gostner JM, Schröcksnadel S, Becker K, Jenny M, Schennach H, Uberall F, Fuchs D.

FEBS Open Bio. 2012 Aug 17;2:241-5. doi: 10.1016/j.fob.2012.08.004. Print 2012.

11.

The Potential Role of Cannabinoids in Modulating Serotonergic Signaling by Their Influence on Tryptophan Metabolism.

Jenny M, Schröcksnadel S, Überall F, Fuchs D.

Pharmaceuticals (Basel). 2010 Aug 13;3(8):2647-2660. Review.

12.

LPS-induced NF-kappaB expression in THP-1Blue cells correlates with neopterin production and activity of indoleamine 2,3-dioxygenase.

Schroecksnadel S, Jenny M, Kurz K, Klein A, Ledochowski M, Uberall F, Fuchs D.

Biochem Biophys Res Commun. 2010 Sep 3;399(4):642-6. doi: 10.1016/j.bbrc.2010.07.134. Epub 2010 Aug 4.

PMID:
20691158
13.

Identification of mu-crystallin as an androgen-regulated gene in human prostate cancer.

Malinowska K, Cavarretta IT, Susani M, Wrulich OA, Uberall F, Kenner L, Culig Z.

Prostate. 2009 Jul 1;69(10):1109-18. doi: 10.1002/pros.20956.

PMID:
19353593
14.

PKCtheta cooperates with atypical PKCzeta and PKCiota in NF-kappaB transactivation of T lymphocytes.

Gruber T, Fresser F, Jenny M, Uberall F, Leitges M, Baier G.

Mol Immunol. 2008 Jan;45(1):117-26. Epub 2007 Jun 22.

PMID:
17588663
15.

Defining the human targets of phorbol ester and diacylglycerol.

Geiger M, Wrulich OA, Jenny M, Schwaiger W, Grunicke HH, Uberall F.

Curr Opin Mol Ther. 2003 Dec;5(6):631-41. Review.

PMID:
14755890
16.

PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation.

Chou FL, Hill JM, Hsieh JC, Pouyssegur J, Brunet A, Glading A, Uberall F, Ramos JW, Werner MH, Ginsberg MH.

J Biol Chem. 2003 Dec 26;278(52):52587-97. Epub 2003 Sep 23.

17.

AKT1/PKBalpha is recruited to lipid rafts and activated downstream of PKC isotypes in CD3-induced T cell signaling.

Bauer B, Jenny M, Fresser F, Uberall F, Baier G.

FEBS Lett. 2003 Apr 24;541(1-3):155-62.

18.

Replicative senescence of human fibroblasts: the role of Ras-dependent signaling and oxidative stress.

Hütter E, Unterluggauer H, Uberall F, Schramek H, Jansen-Dürr P.

Exp Gerontol. 2002 Oct-Nov;37(10-11):1165-74.

PMID:
12470828
19.

Motility enhancement by tumor-derived mutant E-cadherin is sensitive to treatment with epidermal growth factor receptor and phosphatidylinositol 3-kinase inhibitors.

Fuchs M, Hutzler P, Brunner I, Schlegel J, Mages J, Reuning U, Hapke S, Duyster J, Hirohashi S, Genda T, Sakamoto M, Uberall F, Höfler H, Becker KF, Luber B.

Exp Cell Res. 2002 Jun 10;276(2):129-41.

PMID:
12027444
20.

Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase.

Mahboobi S, Teller S, Pongratz H, Hufsky H, Sellmer A, Botzki A, Uecker A, Beckers T, Baasner S, Schächtele C, Uberall F, Kassack MU, Dove S, Böhmer FD.

J Med Chem. 2002 Feb 28;45(5):1002-18.

PMID:
11855980
21.

Regulation of phospholipase D isoenzymes by transforming Ras and atypical protein kinase C-iota.

Mwanjewe J, Spitaler M, Ebner M, Windegger M, Geiger M, Kampfer S, Hofmann J, Uberall F, Grunicke HH.

Biochem J. 2001 Oct 1;359(Pt 1):211-7.

22.

Protein kinase C isoforms involved in the transcriptional activation of cyclin D1 by transforming Ha-Ras.

Kampfer S, Windegger M, Hochholdinger F, Schwaiger W, Pestell RG, Baier G, Grunicke HH, Uberall F.

J Biol Chem. 2001 Nov 16;276(46):42834-42. Epub 2001 Sep 10.

23.

Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cells.

Bauer B, Krumböck N, Fresser F, Hochholdinger F, Spitaler M, Simm A, Uberall F, Schraven B, Baier G.

J Biol Chem. 2001 Aug 24;276(34):31627-34. Epub 2001 Jun 15.

24.

Elements of signal transduction in drug discovery with special reference to inhibitors of protein kinase C.

Grunicke HH, Kampfer S, Spitaler M, Hochholdinger F, Baier G, Uberall F.

Ernst Schering Res Found Workshop. 2001;(34):81-99. Review. No abstract available.

PMID:
11394049
25.

Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling.

Glading A, Uberall F, Keyse SM, Lauffenburger DA, Wells A.

J Biol Chem. 2001 Jun 29;276(26):23341-8. Epub 2001 Apr 23.

26.

T cell expressed PKCtheta demonstrates cell-type selective function.

Bauer B, Krumböck N, Ghaffari-Tabrizi N, Kampfer S, Villunger A, Wilda M, Hameister H, Utermann G, Leitges M, Uberall F, Baier G.

Eur J Immunol. 2000 Dec;30(12):3645-54.

27.

Photo-induced inactivation of protein kinase calpha by dequalinium inhibits motility of murine melanoma cells.

Sullivan RM, Stone M, Marshall JF, Uberall F, Rotenberg SA.

Mol Pharmacol. 2000 Oct;58(4):729-37.

PMID:
10999942
28.

Unique structural and functional properties of the ATP-binding domain of atypical protein kinase C-iota.

Spitaler M, Villunger A, Grunicke H, Uberall F.

J Biol Chem. 2000 Oct 27;275(43):33289-96.

29.

Implication of atypical protein kinase C isozymes lambda and zeta in Ras mediated reorganization of the actin cytoskeleton and cyclin D1-induction.

Hellbert K, Kampfer S, Maly K, Hochholdinger F, Mwanjewe J, Baier G, Uberall F, Grunicke HH.

Adv Enzyme Regul. 2000;40:49-62. Review. No abstract available.

PMID:
10828345
30.

Nuclear mitogen-activated protein kinase activation by protein kinase czeta during reoxygenation after ischemic hypoxia.

Mizukami Y, Kobayashi S, Uberall F, Hellbert K, Kobayashi N, Yoshida K.

J Biol Chem. 2000 Jun 30;275(26):19921-7.

32.

Synergistic action of protein kinase C theta and calcineurin is sufficient for Fas ligand expression and induction of a crmA-sensitive apoptosis pathway in Jurkat T cells.

Villunger A, Ghaffari-Tabrizi N, Tinhofer I, Krumböck N, Bauer B, Schneider T, Kasibhatla S, Greil R, Baier-Bitterlich G, Uberall F, Green DR, Baier G.

Eur J Immunol. 1999 Nov;29(11):3549-61.

33.

Fructose malabsorption is associated with lower plasma folic acid concentrations in middle-aged subjects.

Ledochowski M, Uberall F, Propst T, Fuchs D.

Clin Chem. 1999 Nov;45(11):2013-4. No abstract available.

34.
35.

Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton.

Uberall F, Hellbert K, Kampfer S, Maly K, Villunger A, Spitaler M, Mwanjewe J, Baier-Bitterlich G, Baier G, Grunicke HH.

J Cell Biol. 1999 Feb 8;144(3):413-25.

36.

Protein kinase Ctheta, a selective upstream regulator of JNK/SAPK and IL-2 promoter activation in Jurkat T cells.

Ghaffari-Tabrizi N, Bauer B, Villunger A, Baier-Bitterlich G, Altman A, Utermann G, Uberall F, Baier G.

Eur J Immunol. 1999 Jan;29(1):132-42.

38.

Characterization of PKC isozyme specific functions in cellular signaling.

Kampfer S, Uberall F, Giselbrecht S, Hellbert K, Baier G, Grunicke HH.

Adv Enzyme Regul. 1998;38:35-48. No abstract available.

PMID:
9762345
39.

Functional granulocyte/macrophage colony stimulating factor receptor is constitutively expressed on neoplastic plasma cells and mediates tumour cell longevity.

Villunger A, Egle A, Kos M, Egle D, Tinhofer I, Henn T, Uberall F, Maly K, Greil R.

Br J Haematol. 1998 Sep;102(4):1069-80.

PMID:
9734660
40.

Transcriptional activation of c-fos by oncogenic Ha-Ras in mouse mammary epithelial cells requires the combined activities of PKC-lambda, epsilon and zeta.

Kampfer S, Hellbert K, Villunger A, Doppler W, Baier G, Grunicke HH, Uberall F.

EMBO J. 1998 Jul 15;17(14):4046-55.

41.

Conventional PKC-alpha, novel PKC-epsilon and PKC-theta, but not atypical PKC-lambda are MARCKS kinases in intact NIH 3T3 fibroblasts.

Uberall F, Giselbrecht S, Hellbert K, Fresser F, Bauer B, Gschwendt M, Grunicke HH, Baier G.

J Biol Chem. 1997 Feb 14;272(7):4072-8.

42.

trans-Activation of the HIV type 1 promoter by 7,8-dihydroneopterin in vitro.

Baier-Bitterlich G, Fuchs D, Zangerle R, Baeuerle PA, Werner ER, Fresser F, Uberall F, Baier G, Wachter H.

AIDS Res Hum Retroviruses. 1997 Jan 20;13(2):173-8.

PMID:
9007202
43.

Effects of the selective bisindolylmaleimide protein kinase C inhibitor GF 109203X on P-glycoprotein-mediated multidrug resistance.

Gekeler V, Boer R, Uberall F, Ise W, Schubert C, Utz I, Hofmann J, Sanders KH, Schächtele C, Klemm K, Grunicke H.

Br J Cancer. 1996 Sep;74(6):897-905.

44.

Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes.

Baier-Bitterlich G, Uberall F, Bauer B, Fresser F, Wachter H, Grunicke H, Utermann G, Altman A, Baier G.

Mol Cell Biol. 1996 Apr;16(4):1842-50.

45.

Cellular signalling as a target in cancer chemotherapy. Phospholipid analogues as inhibitors of mitogenic signal transduction.

Grunicke HH, Maly K, Uberall F, Schubert C, Kindler E, Stekar J, Brachwitz H.

Adv Enzyme Regul. 1996;36:385-407.

PMID:
8869757
46.

Interference of new alkylphospholipid analogues with mitogenic signal transduction.

Maly K, Uberall F, Schubert C, Kindler E, Stekar J, Brachwitz H, Grunicke HH.

Anticancer Drug Des. 1995 Jul;10(5):411-25.

PMID:
7639930
47.

Oxidative stress and apoptosis.

Fuchs D, Gruber A, Uberall F, Wachter H.

Immunol Today. 1994 Oct;15(10):496. No abstract available.

PMID:
7945777
48.

Neopterin derivatives together with cyclic guanosine monophosphate induce c-fos gene expression.

Uberall F, Werner-Felmayer G, Schubert C, Grunicke HH, Wachter H, Fuchs D.

FEBS Lett. 1994 Sep 19;352(1):11-4.

49.
50.

Role of protein kinases in antitumor drug resistance.

Grunicke H, Hofmann J, Utz I, Uberall F.

Ann Hematol. 1994;69 Suppl 1:S1-6. Review.

PMID:
8061107

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