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Items: 1 to 50 of 80

1.

A data-driven interactome of synergistic genes improves network-based cancer outcome prediction.

Allahyar A, Ubels J, de Ridder J.

PLoS Comput Biol. 2019 Feb 6;15(2):e1006657. doi: 10.1371/journal.pcbi.1006657. eCollection 2019 Feb.

2.

Cost-Effectiveness of Colorectal Cancer Screening Strategies-A Systematic Review.

Ran T, Cheng CY, Misselwitz B, Brenner H, Ubels J, Schlander M.

Clin Gastroenterol Hepatol. 2019 Jan 16. pii: S1542-3565(19)30034-5. doi: 10.1016/j.cgh.2019.01.014. [Epub ahead of print]

PMID:
30659991
3.

Predicting treatment benefit in multiple myeloma through simulation of alternative treatment effects.

Ubels J, Sonneveld P, van Beers EH, Broijl A, van Vliet MH, de Ridder J.

Nat Commun. 2018 Jul 27;9(1):2943. doi: 10.1038/s41467-018-05348-5.

4.

Impairment of retinal function in yellow perch (Perca flavescens) by Diplostomum baeri metacercariae.

Ubels JL, DeJong RJ, Hoolsema B, Wurzberger A, Nguyen TT, Blankespoor HD, Blankespoor CL.

Int J Parasitol Parasites Wildl. 2018 May 6;7(2):171-179. doi: 10.1016/j.ijppaw.2018.05.001. eCollection 2018 Aug.

5.

On what basis are medical cost-effectiveness thresholds set? Clashing opinions and an absence of data: a systematic review.

Cameron D, Ubels J, Norström F.

Glob Health Action. 2018;11(1):1447828. doi: 10.1080/16549716.2018.1447828. Review.

6.

TNF-R1 and FADD mediate UVB-Induced activation of K+ channels in corneal epithelial cells.

Boersma PM, Haarsma LD, Schotanus MP, Ubels JL.

Exp Eye Res. 2017 Jan;154:1-9. doi: 10.1016/j.exer.2016.11.003. Epub 2016 Nov 3.

7.

The effect of K(+) on caspase activity of corneal epithelial cells exposed to UVB.

Leerar JR, Glupker CD, Schotanus MP, Ubels JL.

Exp Eye Res. 2016 Oct;151:23-5. doi: 10.1016/j.exer.2016.07.014. Epub 2016 Jul 22. Review.

8.

Apoptosis of Corneal Epithelial Cells Caused by Ultraviolet B-induced Loss of K(+) is Inhibited by Ba(2.).

Glupker CD, Boersma PM, Schotanus MP, Haarsma LD, Ubels JL.

Ocul Surf. 2016 Jul;14(3):401-9. doi: 10.1016/j.jtos.2016.05.001. Epub 2016 May 14.

9.

Involvement of the extrinsic and intrinsic pathways in ultraviolet B-induced apoptosis of corneal epithelial cells.

Ubels JL, Glupker CD, Schotanus MP, Haarsma LD.

Exp Eye Res. 2016 Apr;145:26-35. doi: 10.1016/j.exer.2015.11.003. Epub 2015 Nov 10.

10.

300-Fold increase in production of the Zn2+-dependent dechlorinase TrzN in soluble form via apoenzyme stabilization.

Jackson CJ, Coppin CW, Carr PD, Aleksandrov A, Wilding M, Sugrue E, Ubels J, Paks M, Newman J, Peat TS, Russell RJ, Field M, Weik M, Oakeshott JG, Scott C.

Appl Environ Microbiol. 2014 Jul;80(13):4003-11. doi: 10.1128/AEM.00916-14. Epub 2014 Apr 25.

11.

Bioavailability of antioxidants applied to stratified human corneal epithelial cells.

Stoddard AR, Koetje LR, Mitchell AK, Schotanus MP, Ubels JL.

J Ocul Pharmacol Ther. 2013 Sep;29(7):681-7. doi: 10.1089/jop.2013.0014. Epub 2013 May 2.

PMID:
23634787
12.

Differential regulation of GLUT1 activity in human corneal limbal epithelial cells and fibroblasts.

Kuipers DP, Scripture JP, Gunnink SM, Salie MJ, Schotanus MP, Ubels JL, Louters LL.

Biochimie. 2013 Feb;95(2):258-63. doi: 10.1016/j.biochi.2012.09.022. Epub 2012 Sep 23.

13.

Gene expression in human accessory lacrimal glands of Wolfring.

Ubels JL, Gipson IK, Spurr-Michaud SJ, Tisdale AS, Van Dyken RE, Hatton MP.

Invest Ophthalmol Vis Sci. 2012 Oct 1;53(11):6738-47. doi: 10.1167/iovs.12-10750.

14.

Enhancement of vitamin D metabolites in the eye following vitamin D3 supplementation and UV-B irradiation.

Lin Y, Ubels JL, Schotanus MP, Yin Z, Pintea V, Hammock BD, Watsky MA.

Curr Eye Res. 2012 Oct;37(10):871-8. doi: 10.3109/02713683.2012.688235. Epub 2012 May 25.

15.

Stratified corneal limbal epithelial cells are protected from UVB-induced apoptosis by elevated extracellular K⁺.

Schotanus MP, Koetje LR, Van Dyken RE, Ubels JL.

Exp Eye Res. 2011 Nov;93(5):735-40. doi: 10.1016/j.exer.2011.09.005. Epub 2011 Oct 14.

16.

Effects of peroxide-based contact lens-disinfecting systems on human corneal epithelial cells in vitro.

Konynenbelt BJ, Mlnarik DS, Ubels JL.

Eye Contact Lens. 2011 Sep;37(5):286-97. doi: 10.1097/ICL.0b013e3182182d02.

PMID:
21617537
17.

Potassium ion fluxes in corneal epithelial cells exposed to UVB.

Ubels JL, Van Dyken RE, Louters JR, Schotanus MP, Haarsma LD.

Exp Eye Res. 2011 May;92(5):425-31. doi: 10.1016/j.exer.2011.02.019. Epub 2011 Mar 4.

18.

Inhibition of UV-B induced apoptosis in corneal epithelial cells by potassium channel modulators.

Ubels JL, Schotanus MP, Bardolph SL, Haarsma LD, Koetje LR, Louters JR.

Exp Eye Res. 2010 Feb;90(2):216-22. doi: 10.1016/j.exer.2009.10.005. Epub 2009 Oct 28.

19.

Cytotoxicity testing of multipurpose contact lens solutions using monolayer and stratified cultures of human corneal epithelial cells.

Lim MJ, Hurst RK, Konynenbelt BJ, Ubels JL.

Eye Contact Lens. 2009 Nov;35(6):287-96. doi: 10.1097/ICL.0b013e3181b9e92c.

PMID:
19726996
20.

Elevated extracellular K+ inhibits apoptosis of corneal epithelial cells exposed to UV-B radiation.

Singleton KR, Will DS, Schotanus MP, Haarsma LD, Koetje LR, Bardolph SL, Ubels JL.

Exp Eye Res. 2009 Aug;89(2):140-51. doi: 10.1016/j.exer.2009.02.023. Epub 2009 Mar 14.

PMID:
19289117
21.

Corneal epithelial testing strategies for safety evaluation of ophthalmic formulations.

Hoffman HM, Choi JH, Clousing DP, Ubels JL, McCarey BE, Edelhauser HF.

Cutan Ocul Toxicol. 2007;26(4):311-27.

PMID:
18058306
22.

In vitro alternatives to the use of animals in ocular toxicology testing.

Ubels JL, Clousing DP.

Ocul Surf. 2005 Jul;3(3):126-42.

PMID:
17131018
23.

Gene expression in rat lacrimal gland duct cells collected using laser capture microdissection: evidence for K+ secretion by duct cells.

Ubels JL, Hoffman HM, Srikanth S, Resau JH, Webb CP.

Invest Ophthalmol Vis Sci. 2006 May;47(5):1876-85.

PMID:
16638994
25.

Pre-clinical investigation of the efficacy of an artificial tear solution containing hydroxypropyl-guar as a gelling agent.

Ubels JL, Clousing DP, Van Haitsma TA, Hong BS, Stauffer P, Asgharian B, Meadows D.

Curr Eye Res. 2004 Jun;28(6):437-44.

PMID:
15512952
26.

Corneal permeability in a redesigned corneal holder for the bovine cornea opacity and permeability assay.

Ubels JL, Ditlev JA, Clousing DP, Casterton PL.

Toxicol In Vitro. 2004 Dec;18(6):853-7.

PMID:
15465652
27.

Interactions of testosterone and all-trans retinoic acid in regulation of androgen receptor expression in rat lacrimal gland.

Ubels JL, Veenstra E, Ditlev J, Ingersoll K.

Exp Eye Res. 2003 Dec;77(6):741-8.

PMID:
14609562
28.

Closing address: The academic perspective.

Ubels JL.

Adv Exp Med Biol. 2002;506(Pt B):1341-2. No abstract available.

PMID:
12614076
29.

Topically applied 15-(S)-HETE stimulates mucin production by corneal epithelium.

Ubels JL, Aupperlee MD, Jackson RS 2nd, Van Dyken SJ, McCartney MD.

Adv Exp Med Biol. 2002;506(Pt A):317-21. No abstract available.

PMID:
12613927
30.

Identification of androgen receptors in rabbit lacrimal gland by immunohistochemsitry.

Aupperlee MD, Wertz JT, Ingersoll KE, Ubels JL.

Adv Exp Med Biol. 2002;506(Pt A):137-41. No abstract available.

PMID:
12613900
31.

Investigating live and fixed epithelial and fibroblast cells by atomic force microscopy.

Sinniah K, Paauw J, Ubels J.

Curr Eye Res. 2002 Jul;25(1):61-8.

PMID:
12518245
32.

Down-regulation of androgen receptor expression and inhibition of lacrimal gland cell proliferation by retinoic acid.

Ubels JL, Wertz JT, Ingersoll KE, Jackson RS 2nd, Aupperlee MD.

Exp Eye Res. 2002 Nov;75(5):561-71.

PMID:
12457868
33.

Investigating live and fixed epithelial and fibroblast cells by atomic force microscopy.

Sinniah K, Paauw J, Ubels J.

Curr Eye Res. 2002 Mar;24(3):188-95.

PMID:
12221526
34.

A redesigned corneal holder for the bovine cornea opacity and permeability assay that maintains normal corneal morphology.

Ubels JL, Paauw JD, Casterton PL, Kool DJ.

Toxicol In Vitro. 2002 Oct;16(5):621-8.

PMID:
12206829
35.

The eicosanoid, 15-(S)-HETE, stimulates secretion of mucin-like glycoprotein by the corneal epithelium.

Jackson RS 2nd, Van Dyken SJ, McCartney MD, Ubels JL.

Cornea. 2001 Jul;20(5):516-21.

PMID:
11413409
36.
38.
39.

Conjunctival permeability and ultrastructure. Effects of benzalkonium chloride and artificial tears.

Ubels JL, Woo EM, Watts WJ, Smith LK, Zylstra U, Beaird J, McCartney MD.

Adv Exp Med Biol. 1998;438:723-30. No abstract available.

PMID:
9634960
40.

Expression of nuclear retinoic acid receptor and retinoid X receptor mRNA in the cornea and conjunctiva.

Bossenbroek NM, Sulahian TH, Ubels JL.

Curr Eye Res. 1998 May;17(5):462-9.

PMID:
9617539
41.

The lacrimal gland expresses nuclear retinoid X receptors.

Ubels JL, Sulahian TH, Viel MD.

Curr Eye Res. 1997 May;16(5):511-5.

PMID:
9154391
42.

Biological activity of N-(4-hydroxyphenyl) retinamide-O-glucuronide in corneal and conjunctival cells of rabbits and humans.

Ubels JL, Dennis MH, Mitchell JH, Wiley LA, Curley RW Jr.

Curr Eye Res. 1995 Dec;14(12):1115-24. Erratum in: Curr Eye Res 1996 Feb;15(2):followi.

PMID:
8974841
43.

Nuclear retinoic acid receptors in the lacrimal gland.

Ubels JL, Dennis MH, Rigatti BW, Vergnes JP, Beatty R, Kinchington PR.

Curr Eye Res. 1995 Nov;14(11):1055-62.

PMID:
8585936
44.

Effects of preservative-free artificial tear solutions on corneal epithelial structure and function.

Ubels JL, McCartney MD, Lantz WK, Beaird J, Dayalan A, Edelhauser HF.

Arch Ophthalmol. 1995 Mar;113(3):371-8.

PMID:
7887852
45.
46.

The rabbit lacrimal gland in vitamin A deficiency.

Ubels JL, Harkema JR.

Invest Ophthalmol Vis Sci. 1994 Mar;35(3):1249-53.

PMID:
8125737
47.

Evaluation of effects of a physiologic artificial tear on the corneal epithelial barrier: electrical resistance and carboxyfluorescein permeability.

Ubels JL, Williams KK, Lopez Bernal D, Edelhauser HF.

Adv Exp Med Biol. 1994;350:441-52. Review. No abstract available.

PMID:
8030516
48.

Cellular retinol-binding protein and cellular retinoic acid-binding protein in the lacrimal gland.

Perkovich CL, Ubels JL, Lee SY, Soprano DR.

Exp Eye Res. 1993 May;56(5):513-9.

PMID:
8388804
49.

Artificial tear composition and promotion of recovery of the damaged corneal epithelium.

Lopez Bernal D, Ubels JL.

Cornea. 1993 Mar;12(2):115-20.

PMID:
8500317
50.

Retinyl ester hydrolysis in the rabbit lacrimal gland.

Bernal DL, Ubels JL.

Curr Eye Res. 1992 Sep;11(9):889-98.

PMID:
1424730

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