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Items: 1 to 50 of 149

1.

Carbapenem-resistant Acinetobacter baumannii: in pursuit of an effective treatment.

Piperaki ET, Tzouvelekis LS, Miriagou V, Daikos GL.

Clin Microbiol Infect. 2019 Aug;25(8):951-957. doi: 10.1016/j.cmi.2019.03.014. Epub 2019 Mar 23. Review.

PMID:
30914347
2.

Changes in the rates and population structure of methicillin-resistant Staphylococcus aureus (MRSA) from bloodstream infections: A single-centre experience (2000-2015).

Nikolaras GP, Papaparaskevas J, Samarkos M, Tzouvelekis LS, Psychogiou M, Pavlopoulou I, Goukos D, Polonyfi K, Pantazatou A, Deliolanis I, Smilakou S, Daikos GL.

J Glob Antimicrob Resist. 2019 Jun;17:117-122. doi: 10.1016/j.jgar.2018.11.023. Epub 2018 Dec 12.

PMID:
30553117
3.

Klebsiella pneumoniae: Virulence, Biofilm and Antimicrobial Resistance.

Piperaki ET, Syrogiannopoulos GA, Tzouvelekis LS, Daikos GL.

Pediatr Infect Dis J. 2017 Oct;36(10):1002-1005. doi: 10.1097/INF.0000000000001675. Review. No abstract available.

PMID:
28914748
4.

attI1-Located Small Open Reading Frames ORF-17 and ORF-11 in a Class 1 Integron Affect Expression of a Gene Cassette Possessing a Canonical Shine-Dalgarno Sequence.

Papagiannitsis CC, Tzouvelekis LS, Tzelepi E, Miriagou V.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e02070-16. doi: 10.1128/AAC.02070-16. Print 2017 Mar.

5.

Characterization of a Novel lsa(E)- and lnu(B)-Carrying Structure Located in the Chromosome of a Staphylococcus aureus Sequence Type 398 Strain.

Sarrou S, Liakopoulos A, Tsoumani K, Sagri E, Mathiopoulos KD, Tzouvelekis LS, Miriagou V, Petinaki E.

Antimicrob Agents Chemother. 2015 Nov 23;60(2):1164-6. doi: 10.1128/AAC.01178-15. Print 2016 Feb. No abstract available.

6.

Increased Hydrolysis of Oximino-β-Lactams by CMY-107, a Tyr199Cys Mutant Form of CMY-2 Produced by Escherichia coli.

Kotsakis SD, Miriagou V, Vetouli EE, Bozavoutoglou E, Lebessi E, Tzelepi E, Tzouvelekis LS.

Antimicrob Agents Chemother. 2015 Dec;59(12):7894-8. doi: 10.1128/AAC.01793-15. Epub 2015 Oct 5.

7.

Characterization of a mobilizable IncQ plasmid encoding cephalosporinase CMY-4 in Escherichia coli.

Kotsakis SD, Tzouvelekis LS, Lebessi E, Doudoulakakis A, Bouli T, Tzelepi E, Miriagou V.

Antimicrob Agents Chemother. 2015 May;59(5):2964-6. doi: 10.1128/AAC.05017-14. Epub 2015 Feb 17. No abstract available.

8.

Treating infections caused by carbapenemase-producing Enterobacteriaceae.

Tzouvelekis LS, Markogiannakis A, Piperaki E, Souli M, Daikos GL.

Clin Microbiol Infect. 2014 Sep;20(9):862-72. doi: 10.1111/1469-0691.12697. Epub 2014 Jul 12. Review.

9.

Carbapenemase-producing Klebsiella pneumoniae bloodstream infections: lowering mortality by antibiotic combination schemes and the role of carbapenems.

Daikos GL, Tsaousi S, Tzouvelekis LS, Anyfantis I, Psichogiou M, Argyropoulou A, Stefanou I, Sypsa V, Miriagou V, Nepka M, Georgiadou S, Markogiannakis A, Goukos D, Skoutelis A.

Antimicrob Agents Chemother. 2014;58(4):2322-8. doi: 10.1128/AAC.02166-13. Epub 2014 Feb 10.

10.

Confronting carbapenemase-producing Klebsiella pneumoniae.

Markogiannakis A, Tzouvelekis LS, Psichogiou M, Petinaki E, Daikos GL.

Future Microbiol. 2013 Sep;8(9):1147-61. doi: 10.2217/fmb.13.71. Review.

PMID:
24020742
11.

OmpK35 and OmpK36 porin variants associated with specific sequence types of Klebsiella pneumoniae.

Papagiannitsis CC, Giakkoupi P, Kotsakis SD, Tzelepi E, Tzouvelekis LS, Vatopoulos AC, Miriagou V.

J Chemother. 2013 Aug;25(4):250-4. doi: 10.1179/1973947813Y.0000000075. No abstract available.

PMID:
23906079
12.

KPC-producing, multidrug-resistant Klebsiella pneumoniae sequence type 258 as a typical opportunistic pathogen.

Tzouvelekis LS, Miriagou V, Kotsakis SD, Spyridopoulou K, Athanasiou E, Karagouni E, Tzelepi E, Daikos GL.

Antimicrob Agents Chemother. 2013 Oct;57(10):5144-6. doi: 10.1128/AAC.01052-13. Epub 2013 Jul 15.

13.

Characterization of pKP1780, a novel IncR plasmid from the emerging Klebsiella pneumoniae ST147, encoding the VIM-1 metallo-β-lactamase.

Papagiannitsis CC, Miriagou V, Giakkoupi P, Tzouvelekis LS, Vatopoulos AC.

J Antimicrob Chemother. 2013 Oct;68(10):2259-62. doi: 10.1093/jac/dkt196. Epub 2013 May 27.

PMID:
23711894
14.

Characterization of pKP1433, a novel KPC-2-encoding plasmid from Klebsiella pneumoniae sequence type 340.

Papagiannitsis CC, Miriagou V, Giakkoupi P, Tzouvelekis LS, Vatopoulos AC.

Antimicrob Agents Chemother. 2013 Jul;57(7):3427-9. doi: 10.1128/AAC.00054-13. Epub 2013 Apr 29.

15.

Combined disc methods for the detection of KPC- and/or VIM-positive Klebsiella pneumoniae: improving reliability for the double carbapenemase producers.

Miriagou V, Tzelepi E, Kotsakis SD, Daikos GL, Bou Casals J, Tzouvelekis LS.

Clin Microbiol Infect. 2013 Sep;19(9):E412-5. doi: 10.1111/1469-0691.12238. Epub 2013 Apr 30.

16.

Bloodstream infections caused by carbapenemase-producing Klebsiella pneumoniae: a clinical perspective.

Daikos GL, Markogiannakis A, Souli M, Tzouvelekis LS.

Expert Rev Anti Infect Ther. 2012 Dec;10(12):1393-404. doi: 10.1586/eri.12.138. Review.

PMID:
23253318
17.

Interactions of oximino-substituted boronic acids and β-lactams with the CMY-2-derived extended-spectrum cephalosporinases CMY-30 and CMY-42.

Kotsakis SD, Caselli E, Tzouvelekis LS, Petinaki E, Prati F, Miriagou V.

Antimicrob Agents Chemother. 2013 Feb;57(2):968-76. doi: 10.1128/AAC.01620-12. Epub 2012 Dec 10.

18.

Characterisation of CTX-M-117, a Pro174Gln variant of CTX-M-15 extended-spectrum β-lactamase, from a bovine Escherichia coli isolate.

Hächler H, Kotsakis SD, Tzouvelekis LS, Geser N, Lehner A, Miriagou V, Stephan R.

Int J Antimicrob Agents. 2013 Jan;41(1):94-5. doi: 10.1016/j.ijantimicag.2012.09.011. Epub 2012 Nov 3. No abstract available.

PMID:
23127481
19.

Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions.

Tzouvelekis LS, Markogiannakis A, Psichogiou M, Tassios PT, Daikos GL.

Clin Microbiol Rev. 2012 Oct;25(4):682-707. doi: 10.1128/CMR.05035-11. Review.

20.

Emergence of resistance to fosfomycin used as adjunct therapy in KPC Klebsiella pneumoniae bacteraemia: report of three cases.

Karageorgopoulos DE, Miriagou V, Tzouvelekis LS, Spyridopoulou K, Daikos GL.

J Antimicrob Chemother. 2012 Nov;67(11):2777-9. doi: 10.1093/jac/dks270. Epub 2012 Jul 10. No abstract available.

PMID:
22782489
21.

Characterization of a transmissible plasmid encoding VEB-1 and VIM-1 in Proteus mirabilis.

Papagiannitsis CC, Miriagou V, Kotsakis SD, Tzelepi E, Vatopoulos AC, Petinaki E, Tzouvelekis LS.

Antimicrob Agents Chemother. 2012 Jul;56(7):4024-5. doi: 10.1128/AAC.00470-12. Epub 2012 Apr 30. No abstract available.

22.

Identification of OXA-23-producing Acinetobacter baumannii in Greece, 2010 to 2011.

Liakopoulos A, Miriagou V, Katsifas EA, Karagouni AD, Daikos GL, Tzouvelekis LS, Petinaki E.

Euro Surveill. 2012 Mar 15;17(11). pii: 20117.

23.

Emergence of Escherichia coli sequence type 410 (ST410) with KPC-2 β-lactamase.

Mavroidi A, Miriagou V, Malli E, Stefos A, Dalekos GN, Tzouvelekis LS, Petinaki E.

Int J Antimicrob Agents. 2012 Mar;39(3):247-50. doi: 10.1016/j.ijantimicag.2011.11.003. Epub 2012 Jan 9.

PMID:
22226650
24.

Diversity of acquired β-lactamases amongst Klebsiella pneumoniae in Greek hospitals.

Papagiannitsis CC, Tryfinopoulou K, Giakkoupi P, Pappa O, Polemis M, Tzelepi E, Tzouvelekis LS; Carbapenemase Study Group, Vatopoulos AC.

Int J Antimicrob Agents. 2012 Feb;39(2):178-80. doi: 10.1016/j.ijantimicag.2011.09.024. Epub 2011 Nov 21. No abstract available.

PMID:
22104281
25.

Effects of the Val211Gly substitution on molecular dynamics of the CMY-2 cephalosporinase: implications on hydrolysis of expanded-spectrum cephalosporins.

Kotsakis SD, Tzouvelekis LS, Petinaki E, Tzelepi E, Miriagou V.

Proteins. 2011 Nov;79(11):3180-92. doi: 10.1002/prot.23150. Epub 2011 Aug 30.

PMID:
21989938
26.

Staphylococcus lugdunensis strain with a modified PBP1A/1B expressing resistance to β-lactams.

Kotsakis SD, Tzouvelekis LS, Zerva L, Liakopoulos A, Petinaki E.

Eur J Clin Microbiol Infect Dis. 2012 Feb;31(2):169-72. doi: 10.1007/s10096-011-1289-8. Epub 2011 May 19.

PMID:
21594555
27.

An update of the evolving epidemic of blaKPC-2-carrying Klebsiella pneumoniae in Greece (2009-10).

Giakkoupi P, Papagiannitsis CC, Miriagou V, Pappa O, Polemis M, Tryfinopoulou K, Tzouvelekis LS, Vatopoulos AC.

J Antimicrob Chemother. 2011 Jul;66(7):1510-3. doi: 10.1093/jac/dkr166. Epub 2011 May 4.

PMID:
21543359
28.

Characterization of metallo-beta-lactamase VIM-27, an A57S mutant of VIM-1 associated with Klebsiella pneumoniae ST147.

Papagiannitsis CC, Kotsakis SD, Petinaki E, Vatopoulos AC, Tzelepi E, Miriagou V, Tzouvelekis LS.

Antimicrob Agents Chemother. 2011 Jul;55(7):3570-2. doi: 10.1128/AAC.00238-11. Epub 2011 Apr 25.

29.

Sequence of pR3521, an IncB plasmid from Escherichia coli encoding ACC-4, SCO-1, and TEM-1 beta-lactamases.

Papagiannitsis CC, Tzouvelekis LS, Kotsakis SD, Tzelepi E, Miriagou V.

Antimicrob Agents Chemother. 2011 Jan;55(1):376-81. doi: 10.1128/AAC.00875-10. Epub 2010 Oct 18.

30.

Emergence of Klebsiella pneumoniae of a novel sequence type (ST383) producing VIM-4, KPC-2 and CMY-4 β-lactamases.

Papagiannitsis CC, Giakkoupi P, Vatopoulos AC, Tryfinopoulou K, Miriagou V, Tzouvelekis LS.

Int J Antimicrob Agents. 2010 Dec;36(6):573-4. doi: 10.1016/j.ijantimicag.2010.07.018. Epub 2010 Sep 21. No abstract available.

PMID:
20863669
31.

Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases.

Kotsakis SD, Miriagou V, Tzelepi E, Tzouvelekis LS.

Antimicrob Agents Chemother. 2010 Nov;54(11):4864-71. doi: 10.1128/AAC.00771-10. Epub 2010 Aug 9.

32.

Sequence of pNL194, a 79.3-kilobase IncN plasmid carrying the blaVIM-1 metallo-beta-lactamase gene in Klebsiella pneumoniae.

Miriagou V, Papagiannitsis CC, Kotsakis SD, Loli A, Tzelepi E, Legakis NJ, Tzouvelekis LS.

Antimicrob Agents Chemother. 2010 Oct;54(10):4497-502. doi: 10.1128/AAC.00665-10. Epub 2010 Jul 26.

33.

The ongoing challenge of acquired carbapenemases: a hospital outbreak of Klebsiella pneumoniae simultaneously producing VIM-1 and KPC-2.

Zioga A, Miriagou V, Tzelepi E, Douzinas E, Tsakiri M, Legakis NJ, Daikos GL, Tzouvelekis LS.

Int J Antimicrob Agents. 2010 Aug;36(2):190-1. doi: 10.1016/j.ijantimicag.2010.04.002. Epub 2010 May 26. No abstract available.

PMID:
20510588
34.

Risk factors for bloodstream infection with Klebsiella pneumoniae producing VIM-1 metallo-beta-lactamase.

Daikos GL, Vryonis E, Psichogiou M, Tzouvelekis LS, Liatis S, Petrikkos P, Kosmidis C, Tassios PT, Bamias G, Skoutelis A.

J Antimicrob Chemother. 2010 Apr;65(4):784-8. doi: 10.1093/jac/dkq005. Epub 2010 Jan 27.

PMID:
20106862
35.

GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa.

Kotsakis SD, Papagiannitsis CC, Tzelepi E, Legakis NJ, Miriagou V, Tzouvelekis LS.

Antimicrob Agents Chemother. 2010 Mar;54(3):1331-3. doi: 10.1128/AAC.01561-09. Epub 2010 Jan 11.

36.

Detecting VIM-1 production in Proteus mirabilis by an imipenem-dipicolinic acid double disk synergy test.

Miriagou V, Papagiannitsis CC, Tzelepi E, Casals JB, Legakis NJ, Tzouvelekis LS.

J Clin Microbiol. 2010 Feb;48(2):667-8. doi: 10.1128/JCM.01872-09. Epub 2009 Dec 9. No abstract available.

37.

In vitro activity of tigecycline against 2423 clinical isolates and comparison of the available interpretation breakpoints.

Papaparaskevas J, Tzouvelekis LS, Tsakris A, Pittaras TE, Legakis NJ; Hellenic Tigecycline Study Group.

Diagn Microbiol Infect Dis. 2010 Feb;66(2):187-94. doi: 10.1016/j.diagmicrobio.2009.09.012.

PMID:
19836184
38.

Emerging Klebsiella pneumoniae isolates coproducing KPC-2 and VIM-1 carbapenemases.

Giakkoupi P, Pappa O, Polemis M, Vatopoulos AC, Miriagou V, Zioga A, Papagiannitsis CC, Tzouvelekis LS.

Antimicrob Agents Chemother. 2009 Sep;53(9):4048-50. doi: 10.1128/AAC.00690-09. Epub 2009 Jul 6. No abstract available.

39.

Extended-spectrum properties of CMY-30, a Val211Gly mutant of CMY-2 cephalosporinase.

Kotsakis SD, Papagiannitsis CC, Tzelepi E, Tzouvelekis LS, Miriagou V.

Antimicrob Agents Chemother. 2009 Aug;53(8):3520-3. doi: 10.1128/AAC.00219-09. Epub 2009 May 26.

40.

Prospective observational study of the impact of VIM-1 metallo-beta-lactamase on the outcome of patients with Klebsiella pneumoniae bloodstream infections.

Daikos GL, Petrikkos P, Psichogiou M, Kosmidis C, Vryonis E, Skoutelis A, Georgousi K, Tzouvelekis LS, Tassios PT, Bamia C, Petrikkos G.

Antimicrob Agents Chemother. 2009 May;53(5):1868-73. doi: 10.1128/AAC.00782-08. Epub 2009 Feb 17.

41.

CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids.

Zioga A, Whichard JM, Kotsakis SD, Tzouvelekis LS, Tzelepi E, Miriagou V.

Antimicrob Agents Chemother. 2009 Mar;53(3):1256-9. doi: 10.1128/AAC.01284-08. Epub 2008 Dec 22.

42.

Relative strengths of the class 1 integron promoter hybrid 2 and the combinations of strong and hybrid 1 with an active p2 promoter.

Papagiannitsis CC, Tzouvelekis LS, Miriagou V.

Antimicrob Agents Chemother. 2009 Jan;53(1):277-80. doi: 10.1128/AAC.00912-08. Epub 2008 Nov 10.

43.

Emergence of Serratia liquefaciens and Klebsiella oxytoca with metallo-beta-lactamase-encoding IncW plasmids: further spread of the blaVIM-1-carrying integron In-e541.

Miriagou V, Douzinas EE, Papagiannitsis CC, Piperaki E, Legakis NJ, Tzouvelekis LS.

Int J Antimicrob Agents. 2008 Dec;32(6):540-1. doi: 10.1016/j.ijantimicag.2008.06.022. Epub 2008 Sep 10. No abstract available.

PMID:
18786812
44.

Epidemiology of metalloenzyme-producing Pseudomonas aeruginosa in a tertiary hospital in Greece.

Zappas S, Giakkoupi P, Vourli S, Hadjichristodoulou C, Polemis M, Tzouvelekis LS, Avlami A, Vatopoulos A, Daikos GL, Petrikkos G.

J Chemother. 2008 Jun;20(3):307-11.

PMID:
18606584
45.

Evidence for chromosomal and plasmid location of CMY-2 cephalosporinase gene in Salmonella serotype Typhimurium.

Zioga A, Whichard JM, Joyce KJ, Tzelepi E, Tzouvelekis LS, Miriagou V.

J Antimicrob Chemother. 2008 Jun;61(6):1389-90. doi: 10.1093/jac/dkn116. Epub 2008 Mar 18. No abstract available.

PMID:
18349038
46.

Supplementation of growth media with Zn2+ facilitates detection of VIM-2-producing Pseudomonas aeruginosa.

Giakkoupi P, Vourli S, Polemis M, Kalapothaki V, Tzouvelekis LS, Vatopoulos AC.

J Clin Microbiol. 2008 Apr;46(4):1568-9. doi: 10.1128/JCM.02345-07. Epub 2008 Feb 20. No abstract available.

47.

Outbreak of Acinetobacter baumannii with chromosomally encoded VIM-1 undetectable by imipenem-EDTA synergy tests.

Loli A, Tzouvelekis LS, Gianneli D, Tzelepi E, Miriagou V.

Antimicrob Agents Chemother. 2008 May;52(5):1894-6. doi: 10.1128/AAC.01414-07. Epub 2008 Feb 19. No abstract available.

48.

Ongoing epidemic of blaVIM-1-positive Klebsiella pneumoniae in Athens, Greece: a prospective survey.

Psichogiou M, Tassios PT, Avlamis A, Stefanou I, Kosmidis C, Platsouka E, Paniara O, Xanthaki A, Toutouza M, Daikos GL, Tzouvelekis LS.

J Antimicrob Chemother. 2008 Jan;61(1):59-63. Epub 2007 Nov 13.

PMID:
17999975
49.

Spread of the Streptococcus pneumoniae Taiwan19F-14 clone among children in Greece.

Mavroidi A, Paraskakis I, Pangalis A, Kirikou E, Charisiadou A, Athanasiou T, Tassios PT, Tzouvelekis LS.

Clin Microbiol Infect. 2007 Dec;13(12):1213-6. Epub 2007 Oct 18.

50.

Plasmid-encoded ACC-4, an extended-spectrum cephalosporinase variant from Escherichia coli.

Papagiannitsis CC, Tzouvelekis LS, Tzelepi E, Miriagou V.

Antimicrob Agents Chemother. 2007 Oct;51(10):3763-7. Epub 2007 Jul 30.

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