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Items: 1 to 50 of 171


An one-pot two-step automated synthesis of [18F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans.

Huang YY, Chiu MJ, Yen RF, Tsai CL, Hsieh HY, Chiu CH, Wu CH, Hsin LW, Tzen KY, Cheng CY, Ma KH, Shiue CY.

PLoS One. 2019 Jul 1;14(7):e0217384. doi: 10.1371/journal.pone.0217384. eCollection 2019.


Evaluation of 5-[18F]fluoro-2'-deoxycytidine as a tumor imaging agent: A comparison of [18F]FdUrd, [18F]FLT and [18F]FDG.

Yu HM, Chiu CH, Chen WT, Wu CH, Lin PY, Huang YY, Chen JH, Tzen KY, Shiue CY, Lin WJ.

Appl Radiat Isot. 2019 Jun;148:152-159. doi: 10.1016/j.apradiso.2019.03.034. Epub 2019 Mar 27.


Phase II study of metabolic response to one-cycle chemotherapy in patients with locally advanced esophageal squamous cell carcinoma.

Huang TC, Lin CC, Wu YC, Chia-Hsien Cheng J, Lee JM, Wang HP, Huang PM, Hsu FM, Yeh KH, Cheng AL, Tzen KY, Hsu CH.

J Formos Med Assoc. 2019 Jun;118(6):1024-1030. doi: 10.1016/j.jfma.2018.11.003. Epub 2018 Nov 28.


The Relation Between Brain Amyloid Deposition, Cortical Atrophy, and Plasma Biomarkers in Amnesic Mild Cognitive Impairment and Alzheimer's Disease.

Fan LY, Tzen KY, Chen YF, Chen TF, Lai YM, Yen RF, Huang YY, Shiue CY, Yang SY, Chiu MJ.

Front Aging Neurosci. 2018 Jun 18;10:175. doi: 10.3389/fnagi.2018.00175. eCollection 2018.


High yield one-pot production of [18F]FCH via a modified TRACERlab FxFN module.

Huang YY, Tsai CL, Wen HP, Tzen KY, Yen RF, Shiue CY.

Appl Radiat Isot. 2017 Oct;128:190-198. doi: 10.1016/j.apradiso.2017.07.029. Epub 2017 Jul 15.


Targeting histone deacetylase 4/ubiquitin-conjugating enzyme 9 impairs DNA repair for radiosensitization of hepatocellular carcinoma cells in mice.

Tsai CL, Liu WL, Hsu FM, Yang PS, Yen RF, Tzen KY, Cheng AL, Chen PJ, Cheng JC.

Hepatology. 2018 Feb;67(2):586-599. doi: 10.1002/hep.29328. Epub 2017 Dec 26.


Single allele Lmbrd1 knockout results in cardiac hypertrophy.

Tseng LT, Lin CL, Pan KH, Tzen KY, Su MJ, Tsai CT, Li YH, Li PC, Chiang FT, Chang SC, Chang MF.

J Formos Med Assoc. 2018 Jun;117(6):471-479. doi: 10.1016/j.jfma.2017.05.002. Epub 2017 May 23.


Risk Stratification of Pediatric Patients With Neuroblastoma Using Volumetric Parameters of 18F-FDG and 18F-DOPA PET/CT.

Liu CJ, Lu MY, Liu YL, Ko CL, Ko KY, Tzen KY, Chang HH, Yang YL, Jou ST, Hsu WM, Yen RF.

Clin Nucl Med. 2017 Mar;42(3):e142-e148. doi: 10.1097/RLU.0000000000001529.


A multidisciplinary team care approach improves outcomes in high-risk pediatric neuroblastoma patients.

Chang HH, Liu YL, Lu MY, Jou ST, Yang YL, Lin DT, Lin KH, Tzen KY, Yen RF, Lu CC, Liu CJ, Peng SS, Jeng YM, Huang SF, Lee H, Juan HF, Huang MC, Liao YF, Lee YL, Hsu WM.

Oncotarget. 2017 Jan 17;8(3):4360-4372. doi: 10.18632/oncotarget.13874.


Performing Repeated Quantitative Small-Animal PET with an Arterial Input Function Is Routinely Feasible in Rats.

Huang CC, Wu CH, Huang YY, Tzen KY, Chen SF, Tsai ML, Wu HM.

J Nucl Med. 2017 Apr;58(4):611-616. doi: 10.2967/jnumed.116.182402. Epub 2016 Oct 27.


A Novel Potential Positron Emission Tomography Imaging Agent for Vesicular Monoamine Transporter Type 2.

Huang ZR, Tsai CL, Huang YY, Shiue CY, Tzen KY, Yen RF, Hsin LW.

PLoS One. 2016 Sep 9;11(9):e0161295. doi: 10.1371/journal.pone.0161295. eCollection 2016.


Diagnostic Performance of Attenuation-Corrected Myocardial Perfusion Imaging for Coronary Artery Disease: A Systematic Review and Meta-Analysis.

Huang JY, Huang CK, Yen RF, Wu HY, Tu YK, Cheng MF, Lu CC, Tzen KY, Chien KL, Wu YW.

J Nucl Med. 2016 Dec;57(12):1893-1898. Epub 2016 Jul 21. Review.


A two-center study for the quality control of [(18)F]FDG using FASTlab phosphate cassettes.

Huang YY, Taylor S, Koziorowski J, Chang YN, Kao WH, Tzen KY, Shiue CY.

Ann Nucl Med. 2016 Oct;30(8):563-71. doi: 10.1007/s12149-016-1097-4. Epub 2016 Jun 17.


Clinical significance of right ventricular activity on treadmill thallium-201 myocardial single-photon emission computerized tomography using cadmium-zinc-telluride cameras.

Ko KY, Wu YW, Liu CJ, Cheng MF, Yen RF, Tzen KY.

Nucl Med Commun. 2016 Jun;37(6):650-7. doi: 10.1097/MNM.0000000000000494.


Diagnostic FDG and FDOPA positron emission tomography scans distinguish the genomic type and treatment outcome of neuroblastoma.

Liu YL, Lu MY, Chang HH, Lu CC, Lin DT, Jou ST, Yang YL, Lee YL, Huang SF, Jeng YM, Lee H, Miser JS, Lin KH, Liao YF, Hsu WM, Tzen KY.

Oncotarget. 2016 Apr 5;7(14):18774-86. doi: 10.18632/oncotarget.7933.


Search of Unknown Fever Focus Using PET in Critically Ill Children With Complicated Underlying Diseases.

Chang L, Cheng MF, Jou ST, Ko CL, Huang JY, Tzen KY, Yen RF.

Pediatr Crit Care Med. 2016 Feb;17(2):e58-65. doi: 10.1097/PCC.0000000000000601.


Incremental Diagnostic Performance of Combined Parameters in the Detection of Severe Coronary Artery Disease Using Exercise Gated Myocardial Perfusion Imaging.

Liu CJ, Wu YW, Ko KY, Chen YC, Cheng MF, Yen RF, Tzen KY.

PLoS One. 2015 Jul 31;10(7):e0134485. doi: 10.1371/journal.pone.0134485. eCollection 2015.


Improvement of Cerebral Glucose Metabolism in Symptomatic Patients With Carotid Artery Stenosis After Stenting.

Kao HL, Lin MS, Wu WC, Tseng WY, Su MY, Chen YF, Chiu MJ, Wang SY, Yang WS, Tzen KY, Wu YW, Chen MF.

Clin Nucl Med. 2015 Sep;40(9):701-7. doi: 10.1097/RLU.0000000000000880.


Benefits of Neuronal Preferential Systemic Gene Therapy for Neurotransmitter Deficiency.

Lee NC, Muramatsu S, Chien YH, Liu WS, Wang WH, Cheng CH, Hu MK, Chen PW, Tzen KY, Byrne BJ, Hwu WL.

Mol Ther. 2015 Oct;23(10):1572-81. doi: 10.1038/mt.2015.122. Epub 2015 Jul 3.


Impact of residual (18)F-fluoride in (18)F-FDOPA for the diagnosis of neuroblastoma.

Huang YY, Tzen KY, Liu YL, Chiu CH, Tsai CL, Wen HP, Tang KH, Liu CC, Shiue CY.

Ann Nucl Med. 2015 Jul;29(6):489-98. doi: 10.1007/s12149-015-0970-x. Epub 2015 Apr 8.


Sonic Hedgehog inhibition as a strategy to augment radiosensitivity of hepatocellular carcinoma.

Tsai CL, Hsu FM, Tzen KY, Liu WL, Cheng AL, Cheng JC.

J Gastroenterol Hepatol. 2015 Aug;30(8):1317-24. doi: 10.1111/jgh.12931.


Patterns of nodal metastases on 18F-FDG PET/CT in patients with esophageal squamous cell carcinoma are useful to guide treatment planning of radiotherapy.

Liu CJ, Cheng JC, Lee JM, Cheng MF, Tzen KY, Yen RF.

Clin Nucl Med. 2015 May;40(5):384-9. doi: 10.1097/RLU.0000000000000714.


Synergistic Blockade of EGFR and HER2 by New-Generation EGFR Tyrosine Kinase Inhibitor Enhances Radiation Effect in Bladder Cancer Cells.

Tsai YC, Ho PY, Tzen KY, Tuan TF, Liu WL, Cheng AL, Pu YS, Cheng JC.

Mol Cancer Ther. 2015 Mar;14(3):810-20. doi: 10.1158/1535-7163.MCT-13-0951. Epub 2015 Jan 14.


Data-driven respiratory motion tracking and compensation in CZT cameras: a comprehensive analysis of phantom and human images.

Ko CL, Wu YW, Cheng MF, Yen RF, Wu WC, Tzen KY.

J Nucl Cardiol. 2015 Apr;22(2):308-18. doi: 10.1007/s12350-014-9963-8. Epub 2014 Aug 14.


Plasma Aβ but not tau is related to brain PiB retention in early Alzheimer's disease.

Tzen KY, Yang SY, Chen TF, Cheng TW, Horng HE, Wen HP, Huang YY, Shiue CY, Chiu MJ.

ACS Chem Neurosci. 2014 Sep 17;5(9):830-6. doi: 10.1021/cn500101j. Epub 2014 Aug 13.


Targeting Phosphatidylinositide3-Kinase/Akt pathway by BKM120 for radiosensitization in hepatocellular carcinoma.

Liu WL, Gao M, Tzen KY, Tsai CL, Hsu FM, Cheng AL, Cheng JC.

Oncotarget. 2014 Jun 15;5(11):3662-72.


Normal values and symptom correlation of a simplified oatmeal-based gastric emptying study in the Chinese population.

Tseng PH, Wu YW, Lee YC, Cheng MF, Tzen KY, Wang HP, Lin JT, Hsieh ST, Yang WS, Wu MS.

J Gastroenterol Hepatol. 2014 Nov;29(11):1873-82. doi: 10.1111/jgh.12640.


Prognostic value of semiquantification NP-59 SPECT/CT in primary aldosteronism patients after adrenalectomy.

Lu CC, Wu VC, Wu KD, Liu KL, Lin WC, Cheng MF, Tzen KY, Yen RF; TAIPAI Study Group.

Eur J Nucl Med Mol Imaging. 2014 Jul;41(7):1375-84. doi: 10.1007/s00259-014-2692-z. Epub 2014 Feb 14.


Treatment of congenital neurotransmitter deficiencies by intracerebral ventricular injection of an adeno-associated virus serotype 9 vector.

Lee NC, Chien YH, Hu MH, Liu WS, Chen PW, Wang WH, Tzen KY, Byrne BJ, Hwu WL.

Hum Gene Ther. 2014 Mar;25(3):189-98. doi: 10.1089/hum.2013.170. Epub 2014 Jan 7.


Plasma tau as a window to the brain-negative associations with brain volume and memory function in mild cognitive impairment and early Alzheimer's disease.

Chiu MJ, Chen YF, Chen TF, Yang SY, Yang FP, Tseng TW, Chieh JJ, Chen JC, Tzen KY, Hua MS, Horng HE.

Hum Brain Mapp. 2014 Jul;35(7):3132-42. doi: 10.1002/hbm.22390. Epub 2013 Oct 15.


LMBD1 protein serves as a specific adaptor for insulin receptor internalization.

Tseng LT, Lin CL, Tzen KY, Chang SC, Chang MF.

J Biol Chem. 2013 Nov 8;288(45):32424-32. doi: 10.1074/jbc.M113.479527. Epub 2013 Sep 27.


Dopaminergic neuronal imaging in genetic Parkinson's disease: insights into pathogenesis.

McNeill A, Wu RM, Tzen KY, Aguiar PC, Arbelo JM, Barone P, Bhatia K, Barsottini O, Bonifati V, Bostantjopoulou S, Bressan R, Cossu G, Cortelli P, Felicio A, Ferraz HB, Herrera J, Houlden H, Hoexter M, Isla C, Lees A, Lorenzo-Betancor O, Mencacci NE, Pastor P, Pappata S, Pellecchia MT, Silveria-Moriyama L, Varrone A, Foltynie T, Schapira AH.

PLoS One. 2013 Jul 23;8(7):e69190. doi: 10.1371/journal.pone.0069190. Print 2013.


Usefulness of PET/CT for the differentiation and characterization of periampullary lesions.

Cheng MF, Wang HP, Tien YW, Liu KL, Yen RF, Tzen KY, Wu YW.

Clin Nucl Med. 2013 Sep;38(9):703-8. doi: 10.1097/RLU.0b013e31829b266a.


Left ventricle metastasis of esophageal cancer mimicking myocardial infarction in myocardial perfusion scintigraphy.

Cheng MF, Huang TC, Yen RF, Tzen KY, Wu YW.

Int J Cardiol. 2013 Sep 10;167(6):e184-6. doi: 10.1016/j.ijcard.2013.04.063. Epub 2013 Apr 29. No abstract available.


67Ga SPECT/CT aids in the diagnosis of occult infected common iliac artery aneurysm.

Cheng MF, Liu KL, Lin YF, Tzen KY, Yen RF.

Clin Nucl Med. 2013 Jul;38(7):573-5. doi: 10.1097/RLU.0b013e318286c00c.


Regulation of the dopaminergic system in a murine model of aromatic L-amino acid decarboxylase deficiency.

Lee NC, Shieh YD, Chien YH, Tzen KY, Yu IS, Chen PW, Hu MH, Hu MK, Muramatsu S, Ichinose H, Hwu WL.

Neurobiol Dis. 2013 Apr;52:177-90. doi: 10.1016/j.nbd.2012.12.005. Epub 2012 Dec 26.


Characterization of neuroblastic tumors using 18F-FDOPA PET.

Lu MY, Liu YL, Chang HH, Jou ST, Yang YL, Lin KH, Lin DT, Lee YL, Lee H, Wu PY, Luo TY, Shen LH, Huang SF, Liao YF, Hsu WM, Tzen KY; National Taiwan University Neuroblastoma Study Group.

J Nucl Med. 2013 Jan;54(1):42-9. doi: 10.2967/jnumed.112.102772. Epub 2012 Dec 4.


Targeting epidermal growth factor receptor/human epidermal growth factor receptor 2 signalling pathway by a dual receptor tyrosine kinase inhibitor afatinib for radiosensitisation in murine bladder carcinoma.

Tsai YC, Yeh CH, Tzen KY, Ho PY, Tuan TF, Pu YS, Cheng AL, Cheng JC.

Eur J Cancer. 2013 Apr;49(6):1458-66. doi: 10.1016/j.ejca.2012.10.020. Epub 2012 Nov 12.


Gene therapy for aromatic L-amino acid decarboxylase deficiency.

Hwu WL, Muramatsu S, Tseng SH, Tzen KY, Lee NC, Chien YH, Snyder RO, Byrne BJ, Tai CH, Wu RM.

Sci Transl Med. 2012 May 16;4(134):134ra61. doi: 10.1126/scitranslmed.3003640.


Atypical thymic carcinoid associated with coronary artery spasm: incidental finding of myocardial perfusion imaging.

Cheng MF, Hwang JJ, Chen JS, Yu SC, Yen RF, Tzen KY, Wu YW.

Int J Cardiol. 2012 Nov 15;161(2):e31-3. doi: 10.1016/j.ijcard.2012.03.178. Epub 2012 Apr 21. No abstract available. Erratum in: Int J Cardiol. 2013 Oct 30;169(2):154. Huang, Juey-Jen [corrected to Hwang, Juey-Jen].


Postoperative lymphocele demonstrated by lymphoscintigraphy SPECT/CT.

Han DY, Cheng MF, Yen RF, Tzen KY, Wu YW.

Clin Nucl Med. 2012 Apr;37(4):374-6. doi: 10.1097/RLU.0b013e31823eac5e. No abstract available.


Radiosensitizing effect of a phenylbutyrate-derived histone deacetylase inhibitor in hepatocellular carcinoma.

Lu YS, Chou CH, Tzen KY, Gao M, Cheng AL, Kulp SK, Cheng JC.

Int J Radiat Oncol Biol Phys. 2012 Jun 1;83(2):e181-9. doi: 10.1016/j.ijrobp.2011.12.022. Epub 2012 Feb 28.


Asymmetric intense bilateral adrenal uptake on [18F]fluorodeoxyglucose positron emission tomography/computed tomography in a patient with solitary pulmonary nodule.

Cheng MF, Lin MW, Wu CT, Shih SR, Wu YW, Tzen KY, Yen RF.

J Clin Oncol. 2012 Feb 20;30(6):e83-5. doi: 10.1200/JCO.2011.39.1698. Epub 2012 Jan 3. No abstract available.


The effects of 3-month atorvastatin therapy on arterial inflammation, calcification, abdominal adipose tissue and circulating biomarkers.

Wu YW, Kao HL, Huang CL, Chen MF, Lin LY, Wang YC, Lin YH, Lin HJ, Tzen KY, Yen RF, Chi YC, Huang PJ, Yang WS.

Eur J Nucl Med Mol Imaging. 2012 Mar;39(3):399-407. doi: 10.1007/s00259-011-1994-7. Epub 2011 Nov 23.


Active coping with stress suppresses glucose metabolism in the rat hypothalamus.

Ono Y, Lin HC, Tzen KY, Chen HH, Yang PF, Lai WS, Chen JH, Onozuka M, Yen CT.

Stress. 2012 Mar;15(2):207-17. doi: 10.3109/10253890.2011.614296. Epub 2011 Sep 21.


Neuroimaging findings in a brain with Niemann-Pick type C disease.

Huang JY, Peng SF, Yang CC, Yen KY, Tzen KY, Yen RF.

J Formos Med Assoc. 2011 Aug;110(8):537-42. doi: 10.1016/S0929-6646(11)60080-6.


MMP-9 from sublethally irradiated tumor promotes Lewis lung carcinoma cell invasiveness and pulmonary metastasis.

Chou CH, Teng CM, Tzen KY, Chang YC, Chen JH, Cheng JC.

Oncogene. 2012 Jan 26;31(4):458-68. doi: 10.1038/onc.2011.240. Epub 2011 Jun 27.


Development of 68Ga-glycopeptide as an imaging probe for tumor angiogenesis.

Tsao N, Wang CH, Her LJ, Tzen KY, Chen JY, Yu DF, Yang DJ.

J Biomed Biotechnol. 2011;2011:267206. doi: 10.1155/2011/267206. Epub 2011 Apr 7.


Continuous intravenous infusion of prostaglandin E1 improves myocardial perfusion reserve in patients with ischemic heart disease assessed by positron emission tomography: a pilot study.

Huang CL, Wu YW, Wang SS, Tseng CD, Chiang FT, Hsu KL, Lee CM, Tzen KY.

Ann Nucl Med. 2011 Aug;25(7):462-8. doi: 10.1007/s12149-011-0487-x. Epub 2011 Apr 2.


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