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Items: 1 to 50 of 158

1.

Genetic risk of Parkinson disease and progression:: An analysis of 13 longitudinal cohorts.

Iwaki H, Blauwendraat C, Leonard HL, Liu G, Maple-Grødem J, Corvol JC, Pihlstrøm L, van Nimwegen M, Hutten SJ, Nguyen KH, Rick J, Eberly S, Faghri F, Auinger P, Scott KM, Wijeyekoon R, Van Deerlin VM, Hernandez DG, Day-Williams AG, Brice A, Alves G, Noyce AJ, Tysnes OB, Evans JR, Breen DP, Estrada K, Wegel CE, Danjou F, Simon DK, Ravina B, Toft M, Heutink P, Bloem BR, Weintraub D, Barker RA, Williams-Gray CH, van de Warrenburg BP, Van Hilten JJ, Scherzer CR, Singleton AB, Nalls MA.

Neurol Genet. 2019 Jul 9;5(4):e348. doi: 10.1212/NXG.0000000000000348. eCollection 2019 Aug.

2.

The value of cerebrospinal fluid α-synuclein and the tau/α-synuclein ratio for diagnosis of neurodegenerative disorders with Lewy pathology.

Førland MG, Tysnes OB, Aarsland D, Maple-Grødem J, Pedersen KF, Alves G, Lange J.

Eur J Neurol. 2019 Jul 10. doi: 10.1111/ene.14032. [Epub ahead of print]

PMID:
31293044
3.

Combinatory microRNA serum signatures as classifiers of Parkinson's disease.

Patil KS, Basak I, Dalen I, Hoedt E, Lange J, Lunde KA, Liu Y, Tysnes OB, Forsgren L, Aarsland D, Neubert TA, Larsen JP, Alves G, Møller SG.

Parkinsonism Relat Disord. 2019 Apr 11. pii: S1353-8020(19)30205-6. doi: 10.1016/j.parkreldis.2019.04.010. [Epub ahead of print]

PMID:
31003905
4.

Edinburgh Cognitive and Behavioral Amyotrophic Lateral Sclerosis Screen (ECAS) in Norway: Protocol for validation and a prospective cohort study.

Taule T, Spilde Morland A, Arnevik Renså M, Aßmus J, Tysnes OB, Rekand T.

Contemp Clin Trials Commun. 2019 Mar 18;14:100347. doi: 10.1016/j.conctc.2019.100347. eCollection 2019 Jun.

5.

A paradoxical relationship between family history, onset age, and genetic risk in Parkinson's disease.

Kristiansen M, Maple-Grødem J, Alves G, Arepalli S, Hernandez DG, Iwaki H, Nalls MA, Singleton A, Tysnes OB, Toft M, Pihlstrøm L.

Mov Disord. 2019 Feb;34(2):298-299. doi: 10.1002/mds.27555. Epub 2018 Nov 28. No abstract available.

PMID:
30484896
6.

Laryngoscopy Can Be a Valuable Tool for Unexpected Therapeutic Response in Noninvasive Respiratory Interventions.

Andersen TM, Sandnes A, Fondenes O, Clemm H, Halvorsen T, Nilsen RM, Tysnes OB, Heimdal JH, Vollsæter M, Røksund OD.

Respir Care. 2018 Nov;63(11):1459-1461. doi: 10.4187/respcare.06674. No abstract available.

PMID:
30389835
7.

Rare genetic variation in mitochondrial pathways influences the risk for Parkinson's disease.

Gaare JJ, Nido GS, Sztromwasser P, Knappskog PM, Dahl O, Lund-Johansen M, Maple-Grødem J, Alves G, Tysnes OB, Johansson S, Haugarvoll K, Tzoulis C.

Mov Disord. 2018 Oct;33(10):1591-1600. doi: 10.1002/mds.64. Epub 2018 Sep 5.

8.

Hyposmia in a simple smell test is associated with accelerated cognitive decline in early Parkinson's disease.

Gjerde KV, Müller B, Skeie GO, Assmus J, Alves G, Tysnes OB.

Acta Neurol Scand. 2018 Dec;138(6):508-514. doi: 10.1111/ane.13003. Epub 2018 Jul 30.

PMID:
30058142
9.

Inflammation and fatigue in early, untreated Parkinson's Disease.

Herlofson K, Heijnen CJ, Lange J, Alves G, Tysnes OB, Friedman JH, Fagundes CP.

Acta Neurol Scand. 2018 Nov;138(5):394-399. doi: 10.1111/ane.12977. Epub 2018 Jun 26.

PMID:
29947088
10.

Association of glucocerebrosidase polymorphisms and mutations with dementia in incident Parkinson's disease.

Lunde KA, Chung J, Dalen I, Pedersen KF, Linder J, Domellöf ME, Elgh E, Macleod AD, Tzoulis C, Larsen JP, Tysnes OB, Forsgren L, Counsell CE, Alves G, Maple-Grødem J.

Alzheimers Dement. 2018 Oct;14(10):1293-1301. doi: 10.1016/j.jalz.2018.04.006. Epub 2018 May 21.

PMID:
29792872
11.

Is psychosis associated with impulse control disorders in Parkinson's disease?

Erga AH, Bjørnestad A, Tysnes OB, Alves G, Pedersen KF.

Parkinsonism Relat Disord. 2018 Aug;53:110-111. doi: 10.1016/j.parkreldis.2018.04.026. Epub 2018 May 2. No abstract available.

PMID:
29735273
12.

Laryngeal Responses to Mechanically Assisted Cough in Progressing Amyotrophic Lateral Sclerosis.

Andersen TM, Sandnes A, Fondenes O, Nilsen RM, Tysnes OB, Heimdal JH, Clemm HH, Halvorsen T, Vollsæter M, Røksund OD.

Respir Care. 2018 May;63(5):538-549. doi: 10.4187/respcare.05924. Epub 2018 Apr 17.

13.

Alzheimer disease associated variants in SORL1 accelerate dementia development in Parkinson disease.

Maple-Grødem J, Chung J, Lunde KA, Tzoulis C, Tysnes OB, Pedersen KF, Alves G.

Neurosci Lett. 2018 May 1;674:123-126. doi: 10.1016/j.neulet.2018.03.036. Epub 2018 Mar 19.

PMID:
29567423
14.

Dopaminergic and Opioid Pathways Associated with Impulse Control Disorders in Parkinson's Disease.

Erga AH, Dalen I, Ushakova A, Chung J, Tzoulis C, Tysnes OB, Alves G, Pedersen KF, Maple-Grødem J.

Front Neurol. 2018 Feb 28;9:109. doi: 10.3389/fneur.2018.00109. eCollection 2018.

15.

Evolution of cerebrospinal fluid total α-synuclein in Parkinson's disease.

Førland MG, Öhrfelt A, Dalen I, Tysnes OB, Blennow K, Zetterberg H, Pedersen KF, Alves G, Lange J.

Parkinsonism Relat Disord. 2018 Apr;49:4-8. doi: 10.1016/j.parkreldis.2018.01.018. Epub 2018 Jan 31.

PMID:
29409704
16.

No evidence for rare TRAP1 mutations influencing the risk of idiopathic Parkinson's disease.

Gaare JJ, Nido GS, Sztromwasser P, Knappskog PM, Dahl O, Lund-Johansen M, Alves G, Tysnes OB, Johansson S, Haugarvoll K, Tzoulis C.

Brain. 2018 Mar 1;141(3):e16. doi: 10.1093/brain/awx378. No abstract available.

17.

Assessing amyotrophic lateral sclerosis prevalence in Norway from 2009 to 2015 from compulsory nationwide health registers.

Nakken O, Lindstrøm JC, Tysnes OB, Holmøy T.

Amyotroph Lateral Scler Frontotemporal Degener. 2018 May;19(3-4):303-310. doi: 10.1080/21678421.2017.1418004. Epub 2017 Dec 22.

PMID:
29271248
18.

Neuronal complex I deficiency occurs throughout the Parkinson's disease brain, but is not associated with neurodegeneration or mitochondrial DNA damage.

Flønes IH, Fernandez-Vizarra E, Lykouri M, Brakedal B, Skeie GO, Miletic H, Lilleng PK, Alves G, Tysnes OB, Haugarvoll K, Dölle C, Zeviani M, Tzoulis C.

Acta Neuropathol. 2018 Mar;135(3):409-425. doi: 10.1007/s00401-017-1794-7. Epub 2017 Dec 21.

PMID:
29270838
19.

Ultradeep mapping of neuronal mitochondrial deletions in Parkinson's disease.

Nido GS, Dölle C, Flønes I, Tuppen HA, Alves G, Tysnes OB, Haugarvoll K, Tzoulis C.

Neurobiol Aging. 2018 Mar;63:120-127. doi: 10.1016/j.neurobiolaging.2017.10.024. Epub 2017 Dec 8.

20.

The natural history of depressive symptoms in patients with incident Parkinson's disease: a prospective cohort study.

Larsen JP, Dalen I, Pedersen KF, Tysnes OB.

J Neurol. 2017 Dec;264(12):2401-2408. doi: 10.1007/s00415-017-8638-1. Epub 2017 Oct 14.

PMID:
29032408
21.

Development and validation of prognostic survival models in newly diagnosed Parkinson's disease.

Macleod AD, Dalen I, Tysnes OB, Larsen JP, Counsell CE.

Mov Disord. 2018 Jan;33(1):108-116. doi: 10.1002/mds.27177. Epub 2017 Oct 4.

22.

July 2017 ENCALS statement on edaravone.

Al-Chalabi A, Andersen PM, Chandran S, Chio A, Corcia P, Couratier P, Danielsson O, de Carvalho M, Desnuelle C, Grehl T, Grosskreutz J, Holmøy T, Ingre C, Karlsborg M, Kleveland G, Koch JC, Koritnik B, KuzmaKozakiewicz M, Laaksovirta H, Ludolph A, McDermott C, Meyer T, Mitre Ropero B, Mora Pardina J, Nygren I, Petri S, Povedano Panades M, Salachas F, Shaw P, Silani V, Staaf G, Svenstrup K, Talbot K, Tysnes OB, Van Damme P, van der Kooi A, Weber M, Weydt P, Wolf J, Hardiman O, van den Berg LH.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Nov;18(7-8):471-474. doi: 10.1080/21678421.2017.1369125. Epub 2017 Oct 4. Review. No abstract available.

23.

The GBA variant E326K is associated with Parkinson's disease and explains a genome-wide association signal.

Berge-Seidl V, Pihlstrøm L, Maple-Grødem J, Forsgren L, Linder J, Larsen JP, Tysnes OB, Toft M.

Neurosci Lett. 2017 Sep 29;658:48-52. doi: 10.1016/j.neulet.2017.08.040. Epub 2017 Aug 19.

PMID:
28830825
24.

Clinical milestones in Parkinson's disease: A 7-year population-based incident cohort study.

Bjornestad A, Pedersen KF, Tysnes OB, Alves G.

Parkinsonism Relat Disord. 2017 Sep;42:28-33. doi: 10.1016/j.parkreldis.2017.05.025. Epub 2017 May 29.

PMID:
28578818
25.

Use of advanced therapies for Parkinson's disease in Norway.

Ezat B, Pihlstrøm L, Aasly J, Tysnes OB, Egge A, Dietrichs E.

Tidsskr Nor Laegeforen. 2017 May 2;137(9):619-623. doi: 10.4045/tidsskr.16.0711. eCollection 2017 May. English, Norwegian.

26.

Is fatigue associated with cognitive dysfunction in early Parkinson's disease?

Kluger BM, Pedersen KF, Tysnes OB, Ongre SO, Øygarden B, Herlofson K.

Parkinsonism Relat Disord. 2017 Apr;37:87-91. doi: 10.1016/j.parkreldis.2017.02.005. Epub 2017 Feb 7.

PMID:
28202373
27.

Epidemiology of Parkinson's disease.

Tysnes OB, Storstein A.

J Neural Transm (Vienna). 2017 Aug;124(8):901-905. doi: 10.1007/s00702-017-1686-y. Epub 2017 Feb 1. Review.

PMID:
28150045
28.

Natural course of mild cognitive impairment in Parkinson disease: A 5-year population-based study.

Pedersen KF, Larsen JP, Tysnes OB, Alves G.

Neurology. 2017 Feb 21;88(8):767-774. doi: 10.1212/WNL.0000000000003634. Epub 2017 Jan 20.

PMID:
28108638
29.

[Who should investigate chronic fatigue?].

Owe J, Næss H, Tysnes OB.

Tidsskr Nor Laegeforen. 2017 Jan 10;137(1):21-22. doi: 10.4045/tidsskr.16.0902. eCollection 2017 Jan. Norwegian. No abstract available.

30.

Long-term risk of falls in an incident Parkinson's disease cohort: the Norwegian ParkWest study.

Hiorth YH, Alves G, Larsen JP, Schulz J, Tysnes OB, Pedersen KF.

J Neurol. 2017 Feb;264(2):364-372. doi: 10.1007/s00415-016-8365-z. Epub 2016 Dec 20.

PMID:
28000003
31.

Changes in insomnia subtypes in early Parkinson disease.

Tholfsen LK, Larsen JP, Schulz J, Tysnes OB, Gjerstad MD.

Neurology. 2017 Jan 24;88(4):352-358. doi: 10.1212/WNL.0000000000003540. Epub 2016 Dec 16.

PMID:
27986876
32.

Sequence variations in C9orf72 downstream of the hexanucleotide repeat region and its effect on repeat-primed PCR interpretation: a large multinational screening study.

Nordin A, Akimoto C, Wuolikainen A, Alstermark H, Forsberg K, Baumann P, Pinto S, de Carvalho M, Hübers A, Nordin F, Ludolph AC, Weishaupt JH, Meyer T, Grehl T, Schweikert K, Weber M, Burkhardt C, Neuwirth C, Holmøy T, Morita M, Tysnes OB, Benatar M, Wuu J, Lange DJ, Bisgård C, Asgari N, Tarvainen I, Brännström T, Andersen PM.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 May;18(3-4):256-264. doi: 10.1080/21678421.2016.1262423. Epub 2016 Dec 12.

PMID:
27936955
33.

Impulsive and Compulsive Behaviors in Parkinson's Disease: The Norwegian ParkWest Study.

Erga AH, Alves G, Larsen JP, Tysnes OB, Pedersen KF.

J Parkinsons Dis. 2017;7(1):183-191. doi: 10.3233/JPD-160977.

34.

Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease.

Dölle C, Flønes I, Nido GS, Miletic H, Osuagwu N, Kristoffersen S, Lilleng PK, Larsen JP, Tysnes OB, Haugarvoll K, Bindoff LA, Tzoulis C.

Nat Commun. 2016 Nov 22;7:13548. doi: 10.1038/ncomms13548.

35.

Familial aggregation of Parkinson's disease may affect progression of motor symptoms and dementia.

Gaare JJ, Skeie GO, Tzoulis C, Larsen JP, Tysnes OB.

Mov Disord. 2017 Feb;32(2):241-245. doi: 10.1002/mds.26856. Epub 2016 Nov 10.

PMID:
27862270
36.

Loss of independence in early Parkinson disease: A 5-year population-based incident cohort study.

Bjornestad A, Tysnes OB, Larsen JP, Alves G.

Neurology. 2016 Oct 11;87(15):1599-1606. Epub 2016 Sep 2.

PMID:
27590290
37.

Fatigue in early Parkinson's disease: the Norwegian ParkWest study.

Ongre SO, Larsen JP, Tysnes OB, Herlofson K.

Eur J Neurol. 2017 Jan;24(1):105-111. doi: 10.1111/ene.13161. Epub 2016 Sep 26.

PMID:
27670392
38.

Mortality trends of amyotrophic lateral sclerosis in Norway 1951-2014: an age-period-cohort study.

Nakken O, Lindstrøm JC, Tysnes OB, Holmøy T.

J Neurol. 2016 Dec;263(12):2378-2385. Epub 2016 Sep 1.

PMID:
27586392
39.

Validation of a new assay for α-synuclein detection in cerebrospinal fluid.

Førland MG, Öhrfelt A, Oftedal LS, Tysnes OB, Larsen JP, Blennow K, Zetterberg H, Alves G, Lange J.

Clin Chem Lab Med. 2017 Feb 1;55(2):254-260. doi: 10.1515/cclm-2016-0409.

PMID:
27474841
40.

Re: Utredning ved mistenkt kronisk utmattelsessyndrom.

Tysnes OB, Næss H, Owe J.

Tidsskr Nor Laegeforen. 2016 Jun 7;136(10):892. doi: 10.4045/tidsskr.16.0409. eCollection 2016 Jun. Norwegian. No abstract available.

41.

Reliability of Three Disability Scales for Detection of Independence Loss in Parkinson's Disease.

Bjornestad A, Tysnes OB, Larsen JP, Alves G.

Parkinsons Dis. 2016;2016:1941034. doi: 10.1155/2016/1941034. Epub 2016 Apr 24.

42.

Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis.

Andersen T, Sandnes A, Brekka AK, Hilland M, Clemm H, Fondenes O, Tysnes OB, Heimdal JH, Halvorsen T, Vollsæter M, Røksund OD.

Thorax. 2017 Mar;72(3):221-229. doi: 10.1136/thoraxjnl-2015-207555. Epub 2016 May 12.

43.

[Investigation of suspected chronic fatigue syndrome / myalgic encephalomyelitis].

Owe JF, Næss H, Gjerde IO, Bødtker JE, Tysnes OB.

Tidsskr Nor Laegeforen. 2016 Apr 5;136(6):510. doi: 10.4045/tidsskr.16.0187. eCollection 2016 Apr 5. Norwegian. No abstract available.

44.

Investigation of suspected chronic fatigue syndrome/myalgic encephalopathy.

Owe JF, Næss H, Gjerde IO, Bødtker JE, Tysnes OB.

Tidsskr Nor Laegeforen. 2016 Feb 9;136(3):227-32. doi: 10.4045/tidsskr.15.0229. eCollection 2016 Feb 9. English, Norwegian. Erratum in: Tidsskr Nor Laegeforen. 2016 Apr 5;136(6):510.

45.

Association of a BACE1 Gene Polymorphism with Parkinson's Disease in a Norwegian Population.

Lange J, Lunde KA, Sletten C, Møller SG, Tysnes OB, Alves G, Larsen JP, Maple-Grødem J.

Parkinsons Dis. 2015;2015:973298. doi: 10.1155/2015/973298. Epub 2015 Dec 14.

46.

Impact of Falls on Physical Activity in People with Parkinson's Disease.

Hiorth YH, Larsen JP, Lode K, Tysnes OB, Godfrey A, Lord S, Rochester L, Pedersen KF.

J Parkinsons Dis. 2016;6(1):175-82. doi: 10.3233/JPD-150640.

PMID:
26639446
47.

Risk and course of motor complications in a population-based incident Parkinson's disease cohort.

Bjornestad A, Forsaa EB, Pedersen KF, Tysnes OB, Larsen JP, Alves G.

Parkinsonism Relat Disord. 2016 Jan;22:48-53. doi: 10.1016/j.parkreldis.2015.11.007. Epub 2015 Nov 6.

PMID:
26585090
48.

Does vagotomy reduce the risk of Parkinson's disease?

Tysnes OB, Kenborg L, Herlofson K, Steding-Jessen M, Horn A, Olsen JH, Reichmann H.

Ann Neurol. 2015 Dec;78(6):1011-2. doi: 10.1002/ana.24531. Epub 2015 Nov 14. No abstract available.

PMID:
26418122
49.

Development of excessive daytime sleepiness in early Parkinson disease.

Tholfsen LK, Larsen JP, Schulz J, Tysnes OB, Gjerstad MD.

Neurology. 2015 Jul 14;85(2):162-8. doi: 10.1212/WNL.0000000000001737. Epub 2015 Jun 17.

PMID:
26085603
50.

The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease.

Lill CM, Rengmark A, Pihlstrøm L, Fogh I, Shatunov A, Sleiman PM, Wang LS, Liu T, Lassen CF, Meissner E, Alexopoulos P, Calvo A, Chio A, Dizdar N, Faltraco F, Forsgren L, Kirchheiner J, Kurz A, Larsen JP, Liebsch M, Linder J, Morrison KE, Nissbrandt H, Otto M, Pahnke J, Partch A, Restagno G, Rujescu D, Schnack C, Shaw CE, Shaw PJ, Tumani H, Tysnes OB, Valladares O, Silani V, van den Berg LH, van Rheenen W, Veldink JH, Lindenberger U, Steinhagen-Thiessen E; SLAGEN Consortium, Teipel S, Perneczky R, Hakonarson H, Hampel H, von Arnim CAF, Olsen JH, Van Deerlin VM, Al-Chalabi A, Toft M, Ritz B, Bertram L.

Alzheimers Dement. 2015 Dec;11(12):1407-1416. doi: 10.1016/j.jalz.2014.12.009. Epub 2015 Apr 30.

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