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Items: 1 to 50 of 142

1.

Development of a peptide-based fluorescent probe for biological heme monitoring.

Newton LD, Pascu SI, Tyrrell RM, Eggleston IM.

Org Biomol Chem. 2019 Jan 16;17(3):467-471. doi: 10.1039/c8ob02290a.

2.

Non-invasive, transdermal, path-selective and specific glucose monitoring via a graphene-based platform.

Lipani L, Dupont BGR, Doungmene F, Marken F, Tyrrell RM, Guy RH, Ilie A.

Nat Nanotechnol. 2018 Jun;13(6):504-511. doi: 10.1038/s41565-018-0112-4. Epub 2018 Apr 9.

PMID:
29632401
3.

Encapsulation of Cadmium Selenide Nanocrystals in Biocompatible Nanotubes: DFT Calculations, X-ray Diffraction Investigations, and Confocal Fluorescence Imaging.

Calatayud DG, Ge H, Kuganathan N, Mirabello V, Jacobs RMJ, Rees NH, Stoppiello CT, Khlobystov AN, Tyrrell RM, Como ED, Pascu SI.

ChemistryOpen. 2018 Jan 18;7(2):144-158. doi: 10.1002/open.201700184. eCollection 2018 Feb.

4.

Development of refractoriness of HO-1 induction to a second treatment with UVA radiation and the involvement of Nrf2 in human skin fibroblasts.

Zhong JL, Raval CM, Nisar MF, Bian C, Zhang J, Yang L, Tyrrell RM.

Photochem Photobiol. 2014 Nov-Dec;90(6):1340-8. doi: 10.1111/php.12343. Epub 2014 Oct 27.

PMID:
25213834
5.

Role of intracellular labile iron, ferritin, and antioxidant defence in resistance of chronically adapted Jurkat T cells to hydrogen peroxide.

Al-Qenaei A, Yiakouvaki A, Reelfs O, Santambrogio P, Levi S, Hall ND, Tyrrell RM, Pourzand C.

Free Radic Biol Med. 2014 Mar;68:87-100. doi: 10.1016/j.freeradbiomed.2013.12.006. Epub 2013 Dec 12.

6.

Effect of short-term reduced physical activity on cardiovascular risk factors in active lean and overweight middle-aged men.

Dixon NC, Hurst TL, Talbot DC, Tyrrell RM, Thompson D.

Metabolism. 2013 Mar;62(3):361-8. doi: 10.1016/j.metabol.2012.08.006. Epub 2012 Sep 17.

PMID:
22995864
7.

The role of Bach1 in ultraviolet A-mediated human heme oxygenase 1 regulation in human skin fibroblasts.

Raval CM, Zhong JL, Mitchell SA, Tyrrell RM.

Free Radic Biol Med. 2012 Jan 1;52(1):227-36. doi: 10.1016/j.freeradbiomed.2011.10.494. Epub 2011 Nov 6.

PMID:
22107958
8.

Modulation of gene expression by the oxidative stress generated in human skin cells by UVA radiation and the restoration of redox homeostasis.

Tyrrell RM.

Photochem Photobiol Sci. 2012 Jan;11(1):135-47. doi: 10.1039/c1pp05222e. Epub 2011 Oct 19.

PMID:
22008784
9.

Iron, oxidative stress and the example of solar ultraviolet A radiation.

Aroun A, Zhong JL, Tyrrell RM, Pourzand C.

Photochem Photobiol Sci. 2012 Jan;11(1):118-34. doi: 10.1039/c1pp05204g. Epub 2011 Oct 11. Review.

PMID:
21986918
10.

Fluorescent gallium and indium bis(thiosemicarbazonates) and their radiolabelled analogues: synthesis, structures and cellular confocal fluorescence imaging investigations.

Arrowsmith RL, Waghorn PA, Jones MW, Bauman A, Brayshaw SK, Hu Z, Kociok-Köhn G, Mindt TL, Tyrrell RM, Botchway SW, Dilworth JR, Pascu SI.

Dalton Trans. 2011 Jun 21;40(23):6238-52. doi: 10.1039/c1dt10126a. Epub 2011 May 19.

PMID:
21594287
11.

Markers of chronic inflammation with short-term changes in physical activity.

Lund AJ, Hurst TL, Tyrrell RM, Thompson D.

Med Sci Sports Exerc. 2011 Apr;43(4):578-83. doi: 10.1249/MSS.0b013e3181f59dc4.

PMID:
20798662
12.

The heme-heme oxygenase system in wound healing; implications for scar formation.

Wagener FA, Scharstuhl A, Tyrrell RM, Von den Hoff JW, Jozkowicz A, Dulak J, Russel FG, Kuijpers-Jagtman AM.

Curr Drug Targets. 2010 Dec;11(12):1571-85. Review.

PMID:
20704545
13.

Time course of changes in inflammatory markers during a 6-mo exercise intervention in sedentary middle-aged men: a randomized-controlled trial.

Thompson D, Markovitch D, Betts JA, Mazzatti D, Turner J, Tyrrell RM.

J Appl Physiol (1985). 2010 Apr;108(4):769-79. doi: 10.1152/japplphysiol.00822.2009.

14.

Fluorescent copper(II) bis(thiosemicarbazonates): synthesis, structures, electron paramagnetic resonance, radiolabeling, in vitro cytotoxicity and confocal fluorescence microscopy studies.

Pascu SI, Waghorn PA, Kennedy BW, Arrowsmith RL, Bayly SR, Dilworth JR, Christlieb M, Tyrrell RM, Zhong J, Kowalczyk RM, Collison D, Aley PK, Churchill GC, Aigbirhio FI.

Chem Asian J. 2010 Mar 1;5(3):506-19. doi: 10.1002/asia.200900446.

PMID:
20169605
15.

The role of Nrf2 in ultraviolet A mediated heme oxygenase 1 induction in human skin fibroblasts.

Zhong JL, Edwards GP, Raval C, Li H, Tyrrell RM.

Photochem Photobiol Sci. 2010 Jan;9(1):18-24. doi: 10.1039/b9pp00068b. Epub 2009 Oct 28.

PMID:
20062840
16.

A role for Bach1 and HO-2 in suppression of basal and UVA-induced HO-1 expression in human keratinocytes.

Zhong JL, Raval C, Edwards GP, Tyrrell RM.

Free Radic Biol Med. 2010 Jan 15;48(2):196-206. doi: 10.1016/j.freeradbiomed.2009.10.037. Epub 2009 Oct 27.

PMID:
19874887
17.

Active middle-aged men have lower fasting inflammatory markers but the postprandial inflammatory response is minimal and unaffected by physical activity status.

Dixon NC, Hurst TL, Talbot DC, Tyrrell RM, Thompson D.

J Appl Physiol (1985). 2009 Jul;107(1):63-8. doi: 10.1152/japplphysiol.91532.2008. Epub 2009 May 7.

18.

Lycopene supplementation (passata sauce) reduces apoptosis but does not affect oxidant-responsive heme oxygenase-1 in human lymphocytes.

Markovitch D, Tyrrell RM, Tauler P, Frystyk J, Stokes K, Thompson D.

Nutrition. 2009 Jun;25(6):668-75. doi: 10.1016/j.nut.2008.11.022. Epub 2009 Jan 3.

PMID:
19121922
19.

The role of interleukin-6 in UVA protection against UVB-induced immunosuppression.

Reeve VE, Tyrrell RM, Allanson M, Domanski D, Blyth L.

J Invest Dermatol. 2009 Jun;129(6):1539-46. doi: 10.1038/jid.2008.377. Epub 2008 Dec 25.

20.

Acute moderate-intensity exercise in middle-aged men has neither an anti- nor proinflammatory effect.

Markovitch D, Tyrrell RM, Thompson D.

J Appl Physiol (1985). 2008 Jul;105(1):260-5. doi: 10.1152/japplphysiol.00096.2008. Epub 2008 May 8.

21.

The effect of prior exercise on ex vivo induction of heme oxygenase-1 in human lymphocytes.

Markovitch D, Tyrrell RM, Thompson D.

Free Radic Res. 2007 Oct;41(10):1125-34.

PMID:
17886034
22.

Anticipation of subsequent demanding exercise increases the expression of haem oxygenase-1 mRNA in human lymphocytes.

Markovitch D, Tyrrell RM, Thompson D.

Stress. 2008 Jan;11(1):79-82. Epub 2007 Jul 25.

PMID:
17853070
23.

Suppression of UVA-mediated release of labile iron by epicatechin--a link to lysosomal protection.

Basu-Modak S, Ali D, Gordon M, Polte T, Yiakouvaki A, Pourzand C, Rice-Evans C, Tyrrell RM.

Free Radic Biol Med. 2006 Oct 15;41(8):1197-204. Epub 2006 Jun 17.

PMID:
17015166
24.

Potential protection of skin by acute UVA irradiation--from cellular to animal models.

Tyrrell RM, Reeve VE.

Prog Biophys Mol Biol. 2006 Sep;92(1):86-91. Epub 2006 Feb 28. Review.

PMID:
16620921
25.

Exercise-induced expression of heme oxygenase-1 in human lymphocytes.

Thompson D, Basu-Modak S, Gordon M, Poore S, Markovitch D, Tyrrell RM.

Free Radic Res. 2005 Jan;39(1):63-9.

PMID:
15875813
26.

Susceptibility of skin cells to UVA-induced necrotic cell death reflects the intracellular level of labile iron.

Zhong JL, Yiakouvaki A, Holley P, Tyrrell RM, Pourzand C.

J Invest Dermatol. 2004 Oct;123(4):771-80.

27.

Regulation of heme oxygenase-1 gene transcription: recent advances and highlights from the International Conference (Uppsala, 2003) on Heme Oxygenase.

Alam J, Igarashi K, Immenschuh S, Shibahara S, Tyrrell RM.

Antioxid Redox Signal. 2004 Oct;6(5):924-33. Review.

PMID:
15345152
28.

Solar ultraviolet A radiation: an oxidizing skin carcinogen that activates heme oxygenase-1.

Tyrrell RM.

Antioxid Redox Signal. 2004 Oct;6(5):835-40. Review.

PMID:
15345143
29.

Involvement of lipid peroxidation and organic peroxides in UVA-induced matrix metalloproteinase-1 expression.

Polte T, Tyrrell RM.

Free Radic Biol Med. 2004 Jun 15;36(12):1566-74.

PMID:
15182858
30.
31.

Epicatechin and its methylated metabolite attenuate UVA-induced oxidative damage to human skin fibroblasts.

Basu-Modak S, Gordon MJ, Dobson LH, Spencer JP, Rice-Evans C, Tyrrell RM.

Free Radic Biol Med. 2003 Oct 15;35(8):910-21.

PMID:
14556855
32.

Beta-carotene suppresses UVA-induced HO-1 gene expression in cultured FEK4.

Trekli MC, Riss G, Goralczyk R, Tyrrell RM.

Free Radic Biol Med. 2003 Feb 15;34(4):456-64.

PMID:
12566071
33.

A novel iron chelator that does not induce HIF-1 activity.

Creighton-Gutteridge M, Tyrrell RM.

Free Radic Biol Med. 2002 Aug 1;33(3):356-63.

PMID:
12126757
34.

Tea flavonoids and cardiovascular health.

Riemersma RA, Rice-Evans CA, Tyrrell RM, Clifford MN, Lean ME.

QJM. 2001 May;94(5):277-82. Review.

PMID:
11353103
35.

An HPLC method to detect heme oxygenase activity.

Ryter SW, Tyrrell RM.

Curr Protoc Toxicol. 2001 May;Chapter 9:Unit 9.6. doi: 10.1002/0471140856.tx0906s05.

PMID:
23045071
36.
37.

Epicatechin and its in vivo metabolite, 3'-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation.

Spencer JP, Schroeter H, Kuhnle G, Srai SK, Tyrrell RM, Hahn U, Rice-Evans C.

Biochem J. 2001 Mar 15;354(Pt 3):493-500.

38.

Heme oxygenase activity. Current methods and applications.

Ryter SW, Kvam E, Tyrrell RM.

Methods Mol Biol. 2000;99:369-91. Review. No abstract available.

PMID:
10909094
39.

Approaches to define the involvement of reactive oxygen species and iron in ultraviolet-A inducible gene expression.

Pourzand C, Reelfs O, Tyrrell RM.

Methods Mol Biol. 2000;99:257-76. Review. No abstract available.

PMID:
10909089
40.

Role for singlet oxygen in biological effects of ultraviolet A radiation.

Tyrrell RM.

Methods Enzymol. 2000;319:290-6. No abstract available.

PMID:
10907520
41.

Interactions between the UVA and UVB wavebands relevant for immune function and carcinogenesis.

Reeve VE, Tyrrell RM, Shen J.

Redox Rep. 2000;5(1):50-1. No abstract available.

PMID:
10905546
42.

Heme oxygenase activity causes transient hypersensitivity to oxidative ultraviolet A radiation that depends on release of iron from heme.

Kvam E, Hejmadi V, Ryter S, Pourzand C, Tyrrell RM.

Free Radic Biol Med. 2000 Apr 15;28(8):1191-6.

PMID:
10889448
43.

Modulation of c-jun and c-fos transcription by UVB and UVA radiations in human dermal fibroblasts and KB cells.

Soriani M, Hejmadi V, Tyrrell RM.

Photochem Photobiol. 2000 May;71(5):551-8.

PMID:
10818785
44.

Characterization of photosensitivity in the Smith-Lemli-Opitz syndrome: a new congenital photosensitivity syndrome.

Anstey AV, Ryan A, Rhodes LE, Charman CR, Arlett CF, Tyrrell RM, Taylor CR, Pearse AD.

Br J Dermatol. 1999 Sep;141(3):406-14. Review.

PMID:
10583043
45.

Apoptosis, the role of oxidative stress and the example of solar UV radiation.

Pourzand C, Tyrrell RM.

Photochem Photobiol. 1999 Oct;70(4):380-90. Review. No abstract available.

PMID:
10546543
46.
47.

Heme oxygenase induction mediates the photoimmunoprotective activity of UVA radiation in the mouse.

Reeve VE, Tyrrell RM.

Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9317-21.

48.

Ultraviolet A radiation induces immediate release of iron in human primary skin fibroblasts: the role of ferritin.

Pourzand C, Watkin RD, Brown JE, Tyrrell RM.

Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):6751-6.

49.

Direct and indirect modulation of ornithine decarboxylase and cyclooxygenase by UVB radiation in human skin cells.

Soriani M, Luscher P, Tyrrell RM.

Carcinogenesis. 1999 Apr;20(4):727-32.

PMID:
10223206
50.

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