Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 11

1.

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis.

Taylor MJ, von Geldern TW, Ford L, Hübner MP, Marsh K, Johnston KL, Sjoberg HT, Specht S, Pionnier N, Tyrer HE, Clare RH, Cook DAN, Murphy E, Steven A, Archer J, Bloemker D, Lenz F, Koschel M, Ehrens A, Metuge HM, Chunda VC, Ndongmo Chounna PW, Njouendou AJ, Fombad FF, Carr R, Morton HE, Aljayyoussi G, Hoerauf A, Wanji S, Kempf DJ, Turner JD, Ward SA.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaau2086. doi: 10.1126/scitranslmed.aau2086.

PMID:
30867321
2.

Author Correction: Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.

Aljayyoussi G, Tyrer HE, Ford L, Sjoberg H, Pionnier N, Waterhouse D, Davies J, Gamble J, Metuge H, Cook DAN, Steven A, Sharma R, Guimaraes AF, Clare RH, Cassidy A, Johnston KL, Myhill L, Hayward L, Wanji S, Turner JD, Taylor MJ, Ward SA.

Sci Rep. 2018 Jan 18;8(1):1384. doi: 10.1038/s41598-018-19723-1.

3.

Corrigendum: Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.

Sharma R, Aljayyoussi G, Tyrer HE, Gamble J, Hayward L, Guimaraes AF, Davies J, Waterhouse D, Cook DAN, Myhill LJ, Clare RH, Cassidy A, Steven A, Johnston KL, Ford L, Turner JD, Ward SA, Taylor MJ.

Sci Rep. 2018 Jan 8;8:46934. doi: 10.1038/srep46934.

4.

Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis.

Turner JD, Sharma R, Al Jayoussi G, Tyrer HE, Gamble J, Hayward L, Priestley RS, Murphy EA, Davies J, Waterhouse D, Cook DAN, Clare RH, Cassidy A, Steven A, Johnston KL, McCall J, Ford L, Hemingway J, Ward SA, Taylor MJ.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9712-E9721. doi: 10.1073/pnas.1710845114. Epub 2017 Oct 23.

5.

A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways.

Crompton M, Purnell T, Tyrer HE, Parker A, Ball G, Hardisty-Hughes RE, Gale R, Williams D, Dean CH, Simon MM, Mallon AM, Wells S, Bhutta MF, Burton MJ, Tateossian H, Brown SDM.

PLoS Genet. 2017 Aug 14;13(8):e1006969. doi: 10.1371/journal.pgen.1006969. eCollection 2017 Aug.

6.

Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.

Aljayyoussi G, Tyrer HE, Ford L, Sjoberg H, Pionnier N, Waterhouse D, Davies J, Gamble J, Metuge H, Cook DAN, Steven A, Sharma R, Guimaraes AF, Clare RH, Cassidy A, Johnston KL, Myhill L, Hayward L, Wanji S, Turner JD, Taylor MJ, Ward SA.

Sci Rep. 2017 Mar 16;7(1):210. doi: 10.1038/s41598-017-00322-5. Erratum in: Sci Rep. 2018 Jan 18;8(1):1384.

7.

Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.

Sharma R, Al Jayoussi G, Tyrer HE, Gamble J, Hayward L, Guimaraes AF, Davies J, Waterhouse D, Cook DA, Myhill LJ, Clare RH, Cassidy A, Steven A, Johnston KL, Ford L, Turner JD, Ward SA, Taylor MJ.

Sci Rep. 2016 Mar 21;6:23458. doi: 10.1038/srep23458. Erratum in: Sci Rep. 2018 Jan 08;8:46934.

8.

A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis.

Halliday A, Guimaraes AF, Tyrer HE, Metuge HM, Patrick CN, Arnaud KO, Kwenti TD, Forsbrook G, Steven A, Cook D, Enyong P, Wanji S, Taylor MJ, Turner JD.

Parasit Vectors. 2014 Oct 24;7:472. doi: 10.1186/s13071-014-0472-z.

9.

What have we learned from murine models of otitis media?

Tyrer HE, Crompton M, Bhutta MF.

Curr Allergy Asthma Rep. 2013 Oct;13(5):501-11. doi: 10.1007/s11882-013-0360-1. Review.

PMID:
23775349
10.

A mouse model for osseous heteroplasia.

Cheeseman MT, Vowell K, Hough TA, Jones L, Pathak P, Tyrer HE, Kelly M, Cox R, Warren MV, Peters J.

PLoS One. 2012;7(12):e51835. doi: 10.1371/journal.pone.0051835. Epub 2012 Dec 19.

11.

HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.

Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD.

PLoS Genet. 2011 Oct;7(10):e1002336. doi: 10.1371/journal.pgen.1002336. Epub 2011 Oct 20.

Supplemental Content

Loading ...
Support Center