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Items: 43

1.

Metagenomic and metatranscriptomic analysis of the microbial community in Swiss-type Maasdam cheese during ripening.

Duru IC, Laine P, Andreevskaya M, Paulin L, Kananen S, Tynkkynen S, Auvinen P, Smolander OP.

Int J Food Microbiol. 2018 Sep 20;281:10-22. doi: 10.1016/j.ijfoodmicro.2018.05.017. Epub 2018 May 19.

2.

Functional genomics provides insights into the role of Propionibacterium freudenreichii ssp. shermanii JS in cheese ripening.

Ojala T, Laine PKS, Ahlroos T, Tanskanen J, Pitkänen S, Salusjärvi T, Kankainen M, Tynkkynen S, Paulin L, Auvinen P.

Int J Food Microbiol. 2017 Jan 16;241:39-48. doi: 10.1016/j.ijfoodmicro.2016.09.022. Epub 2016 Sep 26.

PMID:
27744211
3.

Effect of live and inactivated Lactobacillus rhamnosus GG on experimentally induced rhinovirus colds: randomised, double blind, placebo-controlled pilot trial.

Kumpu M, Kekkonen RA, Korpela R, Tynkkynen S, Järvenpää S, Kautiainen H, Allen EK, Hendley JO, Pitkäranta A, Winther B.

Benef Microbes. 2015;6(5):631-9. doi: 10.3920/BM2014.0164. Epub 2015 Aug 31.

PMID:
26322544
4.

A comparison of REACH-derived no-effect levels for workers with EU indicative occupational exposure limit values and national limit values in Finland.

Tynkkynen S, Santonen T, Stockmann-Juvala H.

Ann Occup Hyg. 2015 May;59(4):401-15. doi: 10.1093/annhyg/meu112. Epub 2015 Jan 30.

PMID:
25638729
5.

Recovery of probiotic Lactobacillus rhamnosus GG in tonsil tissue after oral administration: randomised, placebo-controlled, double-blind clinical trial.

Kumpu M, Swanljung E, Tynkkynen S, Hatakka K, Kekkonen RA, Järvenpää S, Korpela R, Pitkäranta A.

Br J Nutr. 2013 Jun 28;109(12):2240-6. doi: 10.1017/S0007114512004540. Epub 2012 Oct 24.

PMID:
23092692
6.

Effect of acid stress on protein expression and phosphorylation in Lactobacillus rhamnosus GG.

Koponen J, Laakso K, Koskenniemi K, Kankainen M, Savijoki K, Nyman TA, de Vos WM, Tynkkynen S, Kalkkinen N, Varmanen P.

J Proteomics. 2012 Feb 2;75(4):1357-74. doi: 10.1016/j.jprot.2011.11.009. Epub 2011 Nov 16.

PMID:
22119544
7.

Growth phase-associated changes in the proteome and transcriptome of Lactobacillus rhamnosus GG in industrial-type whey medium.

Laakso K, Koskenniemi K, Koponen J, Kankainen M, Surakka A, Salusjärvi T, Auvinen P, Savijoki K, Nyman TA, Kalkkinen N, Tynkkynen S, Varmanen P.

Microb Biotechnol. 2011 Nov;4(6):746-66. doi: 10.1111/j.1751-7915.2011.00275.x. Epub 2011 Sep 1.

8.

Improving the storage stability of Bifidobacterium breve in low pH fruit juice.

Saarela M, Alakomi HL, Mättö J, Ahonen AM, Puhakka A, Tynkkynen S.

Int J Food Microbiol. 2011 Sep 1;149(1):106-10. doi: 10.1016/j.ijfoodmicro.2010.12.002. Epub 2010 Dec 13.

PMID:
21195496
9.

Proteomics and transcriptomics characterization of bile stress response in probiotic Lactobacillus rhamnosus GG.

Koskenniemi K, Laakso K, Koponen J, Kankainen M, Greco D, Auvinen P, Savijoki K, Nyman TA, Surakka A, Salusjärvi T, de Vos WM, Tynkkynen S, Kalkkinen N, Varmanen P.

Mol Cell Proteomics. 2011 Feb;10(2):M110.002741. doi: 10.1074/mcp.M110.002741. Epub 2010 Nov 15.

10.

Persistence of probiotic strains in the gastrointestinal tract when administered as capsules, yoghurt, or cheese.

Saxelin M, Lassig A, Karjalainen H, Tynkkynen S, Surakka A, Vapaatalo H, Järvenpää S, Korpela R, Mutanen M, Hatakka K.

Int J Food Microbiol. 2010 Dec 15;144(2):293-300. doi: 10.1016/j.ijfoodmicro.2010.10.009. Epub 2010 Oct 21.

PMID:
21074284
11.

Characterization of MabA, a modulator of Lactobacillus rhamnosus GG adhesion and biofilm formation.

Vélez MP, Petrova MI, Lebeer S, Verhoeven TL, Claes I, Lambrichts I, Tynkkynen S, Vanderleyden J, De Keersmaecker SC.

FEMS Immunol Med Microbiol. 2010 Aug;59(3):386-98. doi: 10.1111/j.1574-695X.2010.00680.x. Epub 2010 Apr 9.

12.

Mucosal adhesion properties of the probiotic Lactobacillus rhamnosus GG SpaCBA and SpaFED pilin subunits.

von Ossowski I, Reunanen J, Satokari R, Vesterlund S, Kankainen M, Huhtinen H, Tynkkynen S, Salminen S, de Vos WM, Palva A.

Appl Environ Microbiol. 2010 Apr;76(7):2049-57. doi: 10.1128/AEM.01958-09. Epub 2010 Jan 29.

13.

Comparative genomic analysis of Lactobacillus rhamnosus GG reveals pili containing a human- mucus binding protein.

Kankainen M, Paulin L, Tynkkynen S, von Ossowski I, Reunanen J, Partanen P, Satokari R, Vesterlund S, Hendrickx AP, Lebeer S, De Keersmaecker SC, Vanderleyden J, Hämäläinen T, Laukkanen S, Salovuori N, Ritari J, Alatalo E, Korpela R, Mattila-Sandholm T, Lassig A, Hatakka K, Kinnunen KT, Karjalainen H, Saxelin M, Laakso K, Surakka A, Palva A, Salusjärvi T, Auvinen P, de Vos WM.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17193-8. doi: 10.1073/pnas.0908876106. Epub 2009 Sep 17.

14.

Proteome analysis of Lactobacillus rhamnosus GG using 2-D DIGE and mass spectrometry shows differential protein production in laboratory and industrial-type growth media.

Koskenniemi K, Koponen J, Kankainen M, Savijoki K, Tynkkynen S, de Vos WM, Kalkkinen N, Varmanen P.

J Proteome Res. 2009 Nov;8(11):4993-5007. doi: 10.1021/pr9003823.

PMID:
19780546
15.

The effect of age and non-steroidal anti-inflammatory drugs on human intestinal microbiota composition.

Mäkivuokko H, Tiihonen K, Tynkkynen S, Paulin L, Rautonen N.

Br J Nutr. 2010 Jan;103(2):227-34. doi: 10.1017/S0007114509991553. Epub 2009 Aug 25.

PMID:
19703328
16.

Quantitative strain-specific detection of Lactobacillus rhamnosus GG in human faecal samples by real-time PCR.

Ahlroos T, Tynkkynen S.

J Appl Microbiol. 2009 Feb;106(2):506-14. doi: 10.1111/j.1365-2672.2008.04018.x.

17.

Potentially probiotic bacteria induce efficient maturation but differential cytokine production in human monocyte-derived dendritic cells.

Latvala S, Pietila TE, Veckman V, Kekkonen RA, Tynkkynen S, Korpela R, Julkunen I.

World J Gastroenterol. 2008 Sep 28;14(36):5570-83; discussion 5581-2.

18.

In school-aged children a combination of galacto-oligosaccharides and Lactobacillus GG increases bifidobacteria more than Lactobacillus GG on its own.

Piirainen L, Kekkonen RA, Kajander K, Ahlroos T, Tynkkynen S, Nevala R, Korpela R.

Ann Nutr Metab. 2008;52(3):204-8. doi: 10.1159/000138124. Epub 2008 Jun 11.

PMID:
18544974
19.

Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults.

Kekkonen RA, Lummela N, Karjalainen H, Latvala S, Tynkkynen S, Jarvenpaa S, Kautiainen H, Julkunen I, Vapaatalo H, Korpela R.

World J Gastroenterol. 2008 Apr 7;14(13):2029-36.

20.

The effect of ageing with and without non-steroidal anti-inflammatory drugs on gastrointestinal microbiology and immunology.

Tiihonen K, Tynkkynen S, Ouwehand A, Ahlroos T, Rautonen N.

Br J Nutr. 2008 Jul;100(1):130-7. doi: 10.1017/S000711450888871X. Epub 2008 Feb 18.

PMID:
18279548
21.

Effect of prebiotic supplementation on a probiotic bacteria mixture: comparison between a rat model and clinical trials.

Tiihonen K, Suomalainen T, Tynkkynen S, Rautonen N.

Br J Nutr. 2008 Apr;99(4):826-31. Epub 2007 Sep 10.

PMID:
17868490
22.

Effects of anti-Helicobacter pylori treatment and probiotic supplementation on intestinal microbiota.

Myllyluoma E, Ahlroos T, Veijola L, Rautelin H, Tynkkynen S, Korpela R.

Int J Antimicrob Agents. 2007 Jan;29(1):66-72. Epub 2006 Dec 1.

PMID:
17141481
23.

Lactobacillus bacteremia, species identification, and antimicrobial susceptibility of 85 blood isolates.

Salminen MK, Rautelin H, Tynkkynen S, Poussa T, Saxelin M, Valtonen V, Järvinen A.

Clin Infect Dis. 2006 Mar 1;42(5):e35-44. Epub 2006 Jan 25.

PMID:
16447101
24.

Probiotic supplementation improves tolerance to Helicobacter pylori eradication therapy--a placebo-controlled, double-blind randomized pilot study.

Myllyluoma E, Veijola L, Ahlroos T, Tynkkynen S, Kankuri E, Vapaatalo H, Rautelin H, Korpela R.

Aliment Pharmacol Ther. 2005 May 15;21(10):1263-72.

25.

Probiotic and other functional microbes: from markets to mechanisms.

Saxelin M, Tynkkynen S, Mattila-Sandholm T, de Vos WM.

Curr Opin Biotechnol. 2005 Apr;16(2):204-11. Review.

PMID:
15831388
26.

The efficacy and safety of probiotic Lactobacillus rhamnosus GG on prolonged, noninfectious diarrhea in HIV Patients on antiretroviral therapy: a randomized, placebo-controlled, crossover study.

Salminen MK, Tynkkynen S, Rautelin H, Poussa T, Saxelin M, Ristola M, Valtonen V, Järvinen A.

HIV Clin Trials. 2004 Jul-Aug;5(4):183-91.

PMID:
15472792
27.

Lactobacillus bacteremia, clinical significance, and patient outcome, with special focus on probiotic L. rhamnosus GG.

Salminen MK, Rautelin H, Tynkkynen S, Poussa T, Saxelin M, Valtonen V, Järvinen A.

Clin Infect Dis. 2004 Jan 1;38(1):62-9. Epub 2003 Dec 4.

PMID:
14679449
28.

Food-grade host/vector expression system for Lactobacillus casei based on complementation of plasmid-associated phospho-beta-galactosidase gene lacG.

Takala TM, Saris PE, Tynkkynen SS.

Appl Microbiol Biotechnol. 2003 Jan;60(5):564-70. Epub 2002 Nov 7.

PMID:
12536257
29.

Lactobacillus bacteremia during a rapid increase in probiotic use of Lactobacillus rhamnosus GG in Finland.

Salminen MK, Tynkkynen S, Rautelin H, Saxelin M, Vaara M, Ruutu P, Sarna S, Valtonen V, Järvinen A.

Clin Infect Dis. 2002 Nov 15;35(10):1155-60. Epub 2002 Oct 21.

PMID:
12410474
30.

Expression of Bacillus subtilis phytase in Lactobacillus plantarum 755.

Kerovuo J, Tynkkynen S.

Lett Appl Microbiol. 2000 Apr;30(4):325-9.

31.

X-prolyl dipeptidyl aminopeptidase gene (pepX) is part of the glnRA operon in Lactobacillus rhamnosus.

Varmanen P, Savijoki K, Avall S, Palva A, Tynkkynen S.

J Bacteriol. 2000 Jan;182(1):146-54.

32.
33.

Liver abscess due to a Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG.

Rautio M, Jousimies-Somer H, Kauma H, Pietarinen I, Saxelin M, Tynkkynen S, Koskela M.

Clin Infect Dis. 1999 May;28(5):1159-60. No abstract available.

PMID:
10452653
34.

Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes.

Tynkkynen S, Singh KV, Varmanen P.

Int J Food Microbiol. 1998 Jun 16;41(3):195-204.

PMID:
9706787
35.

Cloning and characterization of a prolinase gene (pepR) from Lactobacillus rhamnosus.

Varmanen P, Rantanen T, Palva A, Tynkkynen S.

Appl Environ Microbiol. 1998 May;64(5):1831-6.

36.

Highly bioluminescent Streptococcus thermophilus strain for the detection of diary-relevant antibiotics in milk.

Jacobs MF, Tynkkynen S, Sibakov M.

Appl Microbiol Biotechnol. 1995 Dec;44(3-4):405-12.

PMID:
8597542
37.

High expression of a foreign reporter gene in Streptococcus thermophilus.

Sibakov M, Tynkkynen S, Jacobs M.

Dev Biol Stand. 1995;85:549-54. No abstract available.

PMID:
8586230
38.

Genetic and biochemical characterization of the oligopeptide transport system of Lactococcus lactis.

Tynkkynen S, Buist G, Kunji E, Kok J, Poolman B, Venema G, Haandrikman A.

J Bacteriol. 1993 Dec;175(23):7523-32.

39.

Isolation of a replication region of a large lactococcal plasmid and use in cloning of a nisin resistance determinant.

von Wright A, Wessels S, Tynkkynen S, Saarela M.

Appl Environ Microbiol. 1990 Jul;56(7):2029-35.

40.

Peptide Utilization Encoded by Lactococcus lactis subsp. lactis SSL135 Chromosomal DNA.

Tynkkynen S, von Wright A, Syväoja EL.

Appl Environ Microbiol. 1989 Oct;55(10):2690-5.

41.
42.

Cloning of a Streptococcus lactis subsp. lactis Chromosomal Fragment Associated with the Ability To Grow in Milk.

von Wright A, Tynkkynen S, Suominen M.

Appl Environ Microbiol. 1987 Jul;53(7):1584-8.

43.

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