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Items: 14

1.

Clinical validation of a noninvasive prenatal test for genomewide detection of fetal copy number variants.

Lefkowitz RB, Tynan JA, Liu T, Wu Y, Mazloom AR, Almasri E, Hogg G, Angkachatchai V, Zhao C, Grosu DS, McLennan G, Ehrich M.

Am J Obstet Gynecol. 2016 Aug;215(2):227.e1-227.e16. doi: 10.1016/j.ajog.2016.02.030. Epub 2016 Feb 17.

2.

Application of risk score analysis to low-coverage whole genome sequencing data for the noninvasive detection of trisomy 21, trisomy 18, and trisomy 13.

Tynan JA, Kim SK, Mazloom AR, Zhao C, McLennan G, Tim R, Liu L, Hannum G, Hull A, Bombard AT, Oeth P, Burcham T, van den Boom D, Ehrich M.

Prenat Diagn. 2016 Jan;36(1):56-62. doi: 10.1002/pd.4712. Epub 2015 Dec 23.

PMID:
26505614
3.

Restriction enzyme-mediated enhanced detection of circulating cell-free fetal DNA in maternal plasma.

Tynan JA, Mahboubi P, Cagasan LL, van den Boom D, Ehrich M, Oeth P.

J Mol Diagn. 2011 Jul;13(4):382-9. doi: 10.1016/j.jmoldx.2011.02.001. Epub 2011 May 6.

4.

Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting.

Ehrich M, Deciu C, Zwiefelhofer T, Tynan JA, Cagasan L, Tim R, Lu V, McCullough R, McCarthy E, Nygren AO, Dean J, Tang L, Hutchison D, Lu T, Wang H, Angkachatchai V, Oeth P, Cantor CR, Bombard A, van den Boom D.

Am J Obstet Gynecol. 2011 Mar;204(3):205.e1-11. doi: 10.1016/j.ajog.2010.12.060. Epub 2011 Feb 18.

PMID:
21310373
5.

Multiplexed analysis of circulating cell-free fetal nucleic acids for noninvasive prenatal diagnostic RHD testing.

Tynan JA, Angkachatchai V, Ehrich M, Paladino T, van den Boom D, Oeth P.

Am J Obstet Gynecol. 2011 Mar;204(3):251.e1-6. doi: 10.1016/j.ajog.2010.09.028. Epub 2010 Nov 18.

PMID:
21092930
6.

Ets2 is required for trophoblast stem cell self-renewal.

Wen F, Tynan JA, Cecena G, Williams R, MĂșnera J, Mavrothalassitis G, Oshima RG.

Dev Biol. 2007 Dec 1;312(1):284-99. Epub 2007 Sep 22.

7.

Ets2-dependent microenvironmental support of mouse mammary tumors.

Tynan JA, Wen F, Muller WJ, Oshima RG.

Oncogene. 2005 Oct 20;24(46):6870-6.

PMID:
16007139
8.

Ets2-dependent stromal regulation of mouse mammary tumors.

Man AK, Young LJ, Tynan JA, Lesperance J, Egeblad M, Werb Z, Hauser CA, Muller WJ, Cardiff RD, Oshima RG.

Mol Cell Biol. 2003 Dec;23(23):8614-25.

9.

Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2.

Porter LA, Dellinger RW, Tynan JA, Barnes EA, Kong M, Lenormand JL, Donoghue DJ.

J Cell Biol. 2002 Apr 29;157(3):357-66. Epub 2002 Apr 29.

10.

Rotational coupling of the transmembrane and kinase domains of the Neu receptor tyrosine kinase.

Bell CA, Tynan JA, Hart KC, Meyer AN, Robertson SC, Donoghue DJ.

Mol Biol Cell. 2000 Oct;11(10):3589-99.

11.

Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4.

Hart KC, Robertson SC, Kanemitsu MY, Meyer AN, Tynan JA, Donoghue DJ.

Oncogene. 2000 Jul 6;19(29):3309-20.

12.

RTK mutations and human syndromeswhen good receptors turn bad.

Robertson SC, Tynan JA, Donoghue DJ.

Trends Genet. 2000 Jun;16(6):265-71. Review. Erratum in: Trends Genet 2000 Aug;16(8):368.

PMID:
10827454
13.

Automated Detection of Trinucleotide Repeats in Fragile X Syndrome.

Hamdan H, Tynan JA, Fenwick RA, Leon JA.

Mol Diagn. 1997 Dec;2(4):259-269.

PMID:
10462618
14.

Myasthenia gravis.

Tynan JA.

Lamp. 1980 Jul;37(7):19-26. No abstract available.

PMID:
6901958

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