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Items: 1 to 50 of 51

1.

Genome-wide cfDNA screening: clinical laboratory experience with the first 10,000 cases.

Ehrich M, Tynan J, Mazloom A, Almasri E, McCullough R, Boomer T, Grosu D, Chibuk J.

Genet Med. 2017 Dec;19(12):1332-1337. doi: 10.1038/gim.2017.56. Epub 2017 Jun 15.

PMID:
28617416
2.

Using Targeted Sequencing of Paralogous Sequences for Noninvasive Detection of Selected Fetal Aneuploidies.

Ellison CK, Sun Y, Hogg G, Fox J, Tao H, McCarthy E, Sagoe B, Azab MA, Mazloom AR, Tynan J, Burcham T, Kim SK, van den Boom D, Ehrich M, Jensen TJ.

Clin Chem. 2016 Dec;62(12):1621-1629. Epub 2016 Sep 30.

3.

Reply.

Ehrich M, Grosu D, van den Boom D, Tynan J.

Am J Obstet Gynecol. 2016 Oct;215(4):534-5. doi: 10.1016/j.ajog.2016.06.009. Epub 2016 Jun 15. No abstract available.

PMID:
27316785
4.

Clinical validation of a noninvasive prenatal test for genomewide detection of fetal copy number variants.

Lefkowitz RB, Tynan JA, Liu T, Wu Y, Mazloom AR, Almasri E, Hogg G, Angkachatchai V, Zhao C, Grosu DS, McLennan G, Ehrich M.

Am J Obstet Gynecol. 2016 Aug;215(2):227.e1-227.e16. doi: 10.1016/j.ajog.2016.02.030. Epub 2016 Feb 17.

5.

Application of risk score analysis to low-coverage whole genome sequencing data for the noninvasive detection of trisomy 21, trisomy 18, and trisomy 13.

Tynan JA, Kim SK, Mazloom AR, Zhao C, McLennan G, Tim R, Liu L, Hannum G, Hull A, Bombard AT, Oeth P, Burcham T, van den Boom D, Ehrich M.

Prenat Diagn. 2016 Jan;36(1):56-62. doi: 10.1002/pd.4712. Epub 2015 Dec 23.

PMID:
26505614
6.

Determination of fetal DNA fraction from the plasma of pregnant women using sequence read counts.

Kim SK, Hannum G, Geis J, Tynan J, Hogg G, Zhao C, Jensen TJ, Mazloom AR, Oeth P, Ehrich M, van den Boom D, Deciu C.

Prenat Diagn. 2015 Aug;35(8):810-5. doi: 10.1002/pd.4615. Epub 2015 Jun 3.

PMID:
25967380
7.

Detection of fetal subchromosomal abnormalities by sequencing circulating cell-free DNA from maternal plasma.

Zhao C, Tynan J, Ehrich M, Hannum G, McCullough R, Saldivar JS, Oeth P, van den Boom D, Deciu C.

Clin Chem. 2015 Apr;61(4):608-16. doi: 10.1373/clinchem.2014.233312. Epub 2015 Feb 20.

8.

Noninvasive prenatal detection of sex chromosomal aneuploidies by sequencing circulating cell-free DNA from maternal plasma.

Mazloom AR, Džakula Ž, Oeth P, Wang H, Jensen T, Tynan J, McCullough R, Saldivar JS, Ehrich M, van den Boom D, Bombard AT, Maeder M, McLennan G, Meschino W, Palomaki GE, Canick JA, Deciu C.

Prenat Diagn. 2013 Jun;33(6):591-7. doi: 10.1002/pd.4127.

PMID:
23592550
9.

High-throughput massively parallel sequencing for fetal aneuploidy detection from maternal plasma.

Jensen TJ, Zwiefelhofer T, Tim RC, Džakula Ž, Kim SK, Mazloom AR, Zhu Z, Tynan J, Lu T, McLennan G, Palomaki GE, Canick JA, Oeth P, Deciu C, van den Boom D, Ehrich M.

PLoS One. 2013;8(3):e57381. doi: 10.1371/journal.pone.0057381. Epub 2013 Mar 6.

10.

Adult fingers visualized on neonatal intensive care unit chest radiographs: what you don't see.

Russell J, Burbridge BE, Duncan MD, Tynan J.

Can Assoc Radiol J. 2013 Aug;64(3):236-9. doi: 10.1016/j.carj.2012.04.004. Epub 2012 Aug 9.

11.

Restriction enzyme-mediated enhanced detection of circulating cell-free fetal DNA in maternal plasma.

Tynan JA, Mahboubi P, Cagasan LL, van den Boom D, Ehrich M, Oeth P.

J Mol Diagn. 2011 Jul;13(4):382-9. doi: 10.1016/j.jmoldx.2011.02.001. Epub 2011 May 6.

12.

Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting.

Ehrich M, Deciu C, Zwiefelhofer T, Tynan JA, Cagasan L, Tim R, Lu V, McCullough R, McCarthy E, Nygren AO, Dean J, Tang L, Hutchison D, Lu T, Wang H, Angkachatchai V, Oeth P, Cantor CR, Bombard A, van den Boom D.

Am J Obstet Gynecol. 2011 Mar;204(3):205.e1-11. doi: 10.1016/j.ajog.2010.12.060. Epub 2011 Feb 18.

PMID:
21310373
13.

Multiplexed analysis of circulating cell-free fetal nucleic acids for noninvasive prenatal diagnostic RHD testing.

Tynan JA, Angkachatchai V, Ehrich M, Paladino T, van den Boom D, Oeth P.

Am J Obstet Gynecol. 2011 Mar;204(3):251.e1-6. doi: 10.1016/j.ajog.2010.09.028. Epub 2010 Nov 18.

PMID:
21092930
14.

Hirayama disease.

Tynan J, Frangou E, Voll C, Otani R, Harder S.

Can J Neurol Sci. 2010 Sep;37(5):703-5. No abstract available.

PMID:
21059525
15.

The suitability of matrix assisted laser desorption/ionization time of flight mass spectrometry in a laboratory developed test using cystic fibrosis carrier screening as a model.

Farkas DH, Miltgen NE, Stoerker J, van den Boom D, Highsmith WE, Cagasan L, McCullough R, Mueller R, Tang L, Tynan J, Tate C, Bombard A.

J Mol Diagn. 2010 Sep;12(5):611-9. doi: 10.2353/jmoldx.2010.090233. Epub 2010 Jul 8.

16.

Case of the month #163. Acute lymphoblastic leukaemia.

Bird JR, Tynan JR, Dzus AK, Leswick DA.

Can Assoc Radiol J. 2010 Jun;61(3):177-8, 180-3. doi: 10.1016/j.carj.2009.11.011. No abstract available.

17.

Clinical and neuroimaging findings of Cree leukodystrophy: a retrospective case series.

Harder S, Gourgaris A, Frangou E, Hopp K, Huntsman R, Lowry N, Seshia S, Lemire E, Robinson C, Tynan J.

AJNR Am J Neuroradiol. 2010 Sep;31(8):1418-23. doi: 10.3174/ajnr.A2108. Epub 2010 Apr 29.

18.

Answer to case of the month #161. Internal hernia through the foramen of Winslow.

Mann SA, Tynan J, Warburton R, Bell C, Kriegler S, Stoneham GW.

Can Assoc Radiol J. 2010 Apr;61(2):113-6. doi: 10.1016/j.carj.2009.10.001. No abstract available.

19.

Answer to Case of the Month #159. Traumatic pseudoaneurysm diagnosis and treatment.

Mirakhur A, Tynan JR, Dhir A, Shenouda M.

Can Assoc Radiol J. 2010 Feb;61(1):54-7. doi: 10.1016/j.carj.2009.05.012. No abstract available.

20.

Answer to case of the month #155. Shock bowel.

Mirakhur A, Tynan JR, Dhir A, Stoneham GW.

Can Assoc Radiol J. 2009 Oct;60(4):220-2. doi: 10.1016/j.carj.2009.05.003. No abstract available.

21.

Reduction of adult fingers visualized on pediatric intensive care unit (PICU) chest radiographs after radiation technologist and PICU staff radiation safety education.

Tynan JR, Duncan MD, Burbridge BE.

Can Assoc Radiol J. 2009 Oct;60(4):182-4. doi: 10.1016/j.carj.2009.06.006. Epub 2009 Jul 23.

22.

Metastatic craniopharyngioma: case report and literature review.

Frangou EM, Tynan JR, Robinson CA, Ogieglo LM, Vitali AM.

Childs Nerv Syst. 2009 Sep;25(9):1143-7. doi: 10.1007/s00381-009-0917-4. Epub 2009 Jun 11. Review.

PMID:
19517118
23.

Case of the month #141. Rhombencephalosynapsis.

Tynan J, Szkup P.

Can Assoc Radiol J. 2008 Dec;59(5):275-7. No abstract available.

PMID:
19385157
24.

Ets2 is required for trophoblast stem cell self-renewal.

Wen F, Tynan JA, Cecena G, Williams R, Múnera J, Mavrothalassitis G, Oshima RG.

Dev Biol. 2007 Dec 1;312(1):284-99. Epub 2007 Sep 22.

25.

Answer to case of the month #107. Appendiceal mucocele as a presentation of mucinous adenocarcinoma.

Tynan JR, Marshall GB, Gray RR.

Can Assoc Radiol J. 2006 Apr;57(2):117-9. No abstract available.

PMID:
16944685
26.

Answer to case of the month #110. Magnetic resonance imaging and spectroscopy in Leigh disease.

Tynan JR, Wiebe S, Robinson C, Harder S.

Can Assoc Radiol J. 2006 Jun;57(3):182-4. No abstract available.

PMID:
16881477
27.
28.

Evidence-based radiology problem: subcapsular hematoma secondary to retracted internal-external drain after percutaneous biliary drainage.

Tynan JR, Marshall GB, Larrigan J, Gray RR.

Can Assoc Radiol J. 2005 Jun;56(3):123-7; quiz 128. No abstract available.

PMID:
16144271
29.

A 7-year-old female with hypotonia and atakia.

Tynan J, Szkup P.

Br J Radiol. 2005 Sep;78(933):869-70. No abstract available.

PMID:
16110116
30.

Ets2-dependent microenvironmental support of mouse mammary tumors.

Tynan JA, Wen F, Muller WJ, Oshima RG.

Oncogene. 2005 Oct 20;24(46):6870-6.

PMID:
16007139
31.

Pathologic fracture through a unicameral bone cyst of the pelvis: CT-guided percutaneous curettage, biopsy, and bone matrix injection.

Tynan JR, Schachar NS, Marshall GB, Gray RR.

J Vasc Interv Radiol. 2005 Feb;16(2 Pt 1):293-6.

PMID:
15713933
32.

Ets2-dependent stromal regulation of mouse mammary tumors.

Man AK, Young LJ, Tynan JA, Lesperance J, Egeblad M, Werb Z, Hauser CA, Muller WJ, Cardiff RD, Oshima RG.

Mol Cell Biol. 2003 Dec;23(23):8614-25.

34.

Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2.

Porter LA, Dellinger RW, Tynan JA, Barnes EA, Kong M, Lenormand JL, Donoghue DJ.

J Cell Biol. 2002 Apr 29;157(3):357-66. Epub 2002 Apr 29.

36.

Rotational coupling of the transmembrane and kinase domains of the Neu receptor tyrosine kinase.

Bell CA, Tynan JA, Hart KC, Meyer AN, Robertson SC, Donoghue DJ.

Mol Biol Cell. 2000 Oct;11(10):3589-99.

37.

Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4.

Hart KC, Robertson SC, Kanemitsu MY, Meyer AN, Tynan JA, Donoghue DJ.

Oncogene. 2000 Jul 6;19(29):3309-20.

38.

RTK mutations and human syndromes: when good receptors turn bad

Robertson SC, Tynan J, Donoghue DJ.

Trends Genet. 2000 Aug;16(8):368. No abstract available.

PMID:
10904266
39.

RTK mutations and human syndromeswhen good receptors turn bad.

Robertson SC, Tynan JA, Donoghue DJ.

Trends Genet. 2000 Jun;16(6):265-71. Review. Erratum in: Trends Genet 2000 Aug;16(8):368.

PMID:
10827454
40.

Automated Detection of Trinucleotide Repeats in Fragile X Syndrome.

Hamdan H, Tynan JA, Fenwick RA, Leon JA.

Mol Diagn. 1997 Dec;2(4):259-269.

PMID:
10462618
41.

Wound care. Unity in practice.

Cooper S, Gebhardt K, Tynan J.

Nurs Times. 1998 Feb 18-24;94(7):70-2. No abstract available.

PMID:
9536739
42.

Periodontal status in a Hutterite population.

Hoover J, Tynan J.

Community Dent Oral Epidemiol. 1989 Dec;17(6):330.

PMID:
2591188
43.

Attracting dental graduates to rural locations: evaluation of the Saskatchewan initiative.

McDermott RE, Tynan JJ.

Can J Community Dent. 1988 Summer;3(2):24-8. No abstract available.

PMID:
3268320
44.

Application of the Community Periodontal Index of Treatment Needs (CPITN) in a group of Canadian adults.

Hoover JN, Tynan JJ.

Oral Health. 1986 Oct;76(10):13-5. No abstract available.

PMID:
3466116
45.

Periodontal status of a group of Canadian adults.

Hoover JN, Tynan JJ.

J Can Dent Assoc. 1986 Sep;52(9):761-3. No abstract available.

PMID:
3530401
46.

Oral hygiene habits and periodontal knowledge in a group of Canadian adults--a pilot study.

Hoover JN, Tynan JJ.

Can J Public Health. 1986 Mar-Apr;77(2):154-6. No abstract available.

PMID:
3708501
47.

Pseudomonas aeruginosa in the oral cavity and sputum of patients with cystic fibrosis.

Komiyama K, Tynan JJ, Habbick BF, Duncan DE, Liepert DJ.

Oral Surg Oral Med Oral Pathol. 1985 Jun;59(6):590-4.

PMID:
3925406
48.

Cystic fibrosis and oral health.

Tynan JJ, Komiyama K.

J Can Dent Assoc. 1984 Nov;50(11):833-5. Review. No abstract available.

PMID:
6391624
49.

Myasthenia gravis.

Tynan JA.

Lamp. 1980 Jul;37(7):19-26. No abstract available.

PMID:
6901958
50.

Subphrenic vs. perinephric abscess: anatomic considerations, diagnosis and treatment.

BEACH EW, TYNAN JC.

J Urol. 1955 Sep;74(3):278-90. No abstract available.

PMID:
13252704

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