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Items: 25

1.

Dopamine Is a Siderophore-Like Iron Chelator That Promotes Salmonella enterica Serovar Typhimurium Virulence in Mice.

Dichtl S, Demetz E, Haschka D, Tymoszuk P, Petzer V, Nairz M, Seifert M, Hoffmann A, Brigo N, Würzner R, Theurl I, Karlinsey JE, Fang FC, Weiss G.

MBio. 2019 Feb 5;10(1). pii: e02624-18. doi: 10.1128/mBio.02624-18.

2.

Iron in the Tumor Microenvironment-Connecting the Dots.

Pfeifhofer-Obermair C, Tymoszuk P, Petzer V, Weiss G, Nairz M.

Front Oncol. 2018 Nov 26;8:549. doi: 10.3389/fonc.2018.00549. eCollection 2018. Review.

3.

Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome.

Haschka D, Volani C, Stefani A, Tymoszuk P, Mitterling T, Holzknecht E, Heidbreder A, Coassin S, Sumbalova Z, Seifert M, Dichtl S, Theurl I, Gnaiger E, Kronenberg F, Frauscher B, Högl B, Weiss G.

Mov Disord. 2019 Jan;34(1):114-123. doi: 10.1002/mds.27482. Epub 2018 Oct 11.

PMID:
30311259
4.

The crucial impact of iron deficiency definition for the course of precapillary pulmonary hypertension.

Sonnweber T, Nairz M, Theurl I, Petzer V, Tymoszuk P, Haschka D, Rieger E, Kaessmann B, Deri M, Watzinger K, Steringer-Mascherbauer R, Tancevski I, Weiss G, Löffler-Ragg J.

PLoS One. 2018 Aug 30;13(8):e0203396. doi: 10.1371/journal.pone.0203396. eCollection 2018.

5.

Iron and innate antimicrobial immunity-Depriving the pathogen, defending the host.

Nairz M, Dichtl S, Schroll A, Haschka D, Tymoszuk P, Theurl I, Weiss G.

J Trace Elem Med Biol. 2018 Jul;48:118-133. doi: 10.1016/j.jtemb.2018.03.007. Epub 2018 Mar 10. Review.

PMID:
29773170
6.

Correction for Wu et al., "Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling".

Wu A, Tymoszuk P, Haschka D, Heeke S, Dichtl S, Petzer V, Seifert M, Hilbe R, Sopper S, Talasz H, Bumann D, Lass-Flörl C, Theurl I, Zhang K, Weiss G.

Infect Immun. 2018 Feb 20;86(3). pii: e00881-17. doi: 10.1128/IAI.00881-17. Print 2018 Mar. No abstract available.

7.

Salmonella utilizes zinc to subvert anti-microbial host defense of macrophages via modulation of NF-κB signaling.

Wu A, Tymoszuk P, Haschka D, Heeke S, Dichtl S, Petzer V, Seifert M, Hilbe R, Sopper S, Talasz H, Bumann D, Lass-Flörl C, Theurl I, Zhang K, Weiss G.

Infect Immun. 2017 Sep 5. pii: IAI.00418-17. doi: 10.1128/IAI.00418-17. [Epub ahead of print] Erratum in: Infect Immun. 2018 Feb 20;86(3):.

8.

Genetic and Dietary Iron Overload Differentially Affect the Course of Salmonella Typhimurium Infection.

Nairz M, Schroll A, Haschka D, Dichtl S, Tymoszuk P, Demetz E, Moser P, Haas H, Fang FC, Theurl I, Weiss G.

Front Cell Infect Microbiol. 2017 Apr 11;7:110. doi: 10.3389/fcimb.2017.00110. eCollection 2017.

9.

Langerhans cells and NK cells cooperate in the inhibition of chemical skin carcinogenesis.

Ortner D, Tripp CH, Komenda K, Dubrac S, Zelger B, Hermann M, Doppler W, Tymoszuk PZ, Boon L, Clausen BE, Stoitzner P.

Oncoimmunology. 2016 Nov 18;6(2):e1260215. doi: 10.1080/2162402X.2016.1260215. eCollection 2017.

10.

Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents.

Asshoff M, Petzer V, Warr MR, Haschka D, Tymoszuk P, Demetz E, Seifert M, Posch W, Nairz M, Maciejewski P, Fowles P, Burns CJ, Smith G, Wagner KU, Weiss G, Whitney JA, Theurl I.

Blood. 2017 Mar 30;129(13):1823-1830. doi: 10.1182/blood-2016-09-740092. Epub 2017 Feb 10.

11.

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver.

Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, He S, Gerhardt LM, Holderried TA, Seifert M, Sopper S, Fenn AM, Anzai A, Rattik S, McAlpine C, Theurl M, Wieghofer P, Iwamoto Y, Weber GF, Harder NK, Chousterman BG, Arvedson TL, McKee M, Wang F, Lutz OM, Rezoagli E, Babitt JL, Berra L, Prinz M, Nahrendorf M, Weiss G, Weissleder R, Lin HY, Swirski FK.

Nat Med. 2016 Aug;22(8):945-51. doi: 10.1038/nm.4146. Epub 2016 Jul 18.

12.

Lipocalin 2 drives neutrophilic inflammation in alcoholic liver disease.

Wieser V, Tymoszuk P, Adolph TE, Grander C, Grabherr F, Enrich B, Pfister A, Lichtmanegger L, Gerner R, Drach M, Moser P, Zoller H, Weiss G, Moschen AR, Theurl I, Tilg H.

J Hepatol. 2016 Apr;64(4):872-80. doi: 10.1016/j.jhep.2015.11.037. Epub 2015 Dec 9.

PMID:
26682726
13.

The BH3-only protein BIM contributes to late-stage involution in the mouse mammary gland.

Schuler F, Baumgartner F, Klepsch V, Chamson M, Müller-Holzner E, Watson CJ, Oh S, Hennighausen L, Tymoszuk P, Doppler W, Villunger A.

Cell Death Differ. 2016 Jan;23(1):41-51. doi: 10.1038/cdd.2015.61. Epub 2015 Jun 5.

14.

Secretoneurin gene therapy improves hind limb and cardiac ischaemia in Apo E⁻/⁻ mice without influencing systemic atherosclerosis.

Theurl M, Schgoer W, Albrecht-Schgoer K, Lener D, Wolf D, Wolf M, Demetz E, Tymoszuk P, Tancevski I, Fischer-Colbrie R, Franz WM, Marschang P, Kirchmair R.

Cardiovasc Res. 2015 Jan 1;105(1):96-106. doi: 10.1093/cvr/cvu237. Epub 2014 Nov 5.

PMID:
25377726
15.

In situ proliferation contributes to accumulation of tumor-associated macrophages in spontaneous mammary tumors.

Tymoszuk P, Evens H, Marzola V, Wachowicz K, Wasmer MH, Datta S, Müller-Holzner E, Fiegl H, Böck G, van Rooijen N, Theurl I, Doppler W.

Eur J Immunol. 2014 Aug;44(8):2247-62. doi: 10.1002/eji.201344304. Epub 2014 Jun 16.

16.

High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer.

Tymoszuk P, Charoentong P, Hackl H, Spilka R, Müller-Holzner E, Trajanoski Z, Obrist P, Revillion F, Peyrat JP, Fiegl H, Doppler W.

BMC Cancer. 2014 Apr 12;14:257. doi: 10.1186/1471-2407-14-257.

17.
18.

Replenishment of the B cell compartment after doxorubicin-induced hematopoietic toxicity is facilitated by STAT1.

Datta S, Parajuli N, Tymoszuk P, Ottina E, Parson W, Sgonc R, Villunger A, Doppler W.

J Leukoc Biol. 2014 Jun;95(6):853-66. doi: 10.1189/jlb.0113053. Epub 2013 Dec 2.

PMID:
24295829
19.

Lapatinib and doxorubicin enhance the Stat1-dependent antitumor immune response.

Hannesdóttir L, Tymoszuk P, Parajuli N, Wasmer MH, Philipp S, Daschil N, Datta S, Koller JB, Tripp CH, Stoitzner P, Müller-Holzner E, Wiegers GJ, Sexl V, Villunger A, Doppler W.

Eur J Immunol. 2013 Oct;43(10):2718-29. doi: 10.1002/eji.201242505. Epub 2013 Jul 11.

20.

MMTV-neu mice deficient in STAT1 are susceptible to develop ovarian teratomas.

Hannesdóttir L, Daschil N, Philipp S, Tymoszuk P, Müller-Holzner E, Klima G, Verdorfer I, Doppler W.

Int J Dev Biol. 2012;56(4):279-83. doi: 10.1387/ijdb.113397lh.

21.

EGF activates TTP expression by activation of ELK-1 and EGR-1 transcription factors.

Florkowska M, Tymoszuk P, Balwierz A, Skucha A, Kochan J, Wawro M, Stalinska K, Kasza A.

BMC Mol Biol. 2012 Mar 20;13:8. doi: 10.1186/1471-2199-13-8.

22.

Upregulation of TLR2 and TLR4 in the human adrenocortical cells differentially modulates adrenal steroidogenesis.

Kanczkowski W, Tymoszuk P, Chavakis T, Janitzky V, Weirich T, Zacharowski K, Ehrhart-Bornstein M, Bornstein SR.

Mol Cell Endocrinol. 2011 Apr 10;336(1-2):41-6. doi: 10.1016/j.mce.2010.12.013. Epub 2010 Dec 15.

PMID:
21167252
23.

Abrogation of TLR4 and CD14 expression and signaling in human adrenocortical tumors.

Kanczkowski W, Tymoszuk P, Ehrhart-Bornstein M, Wirth MP, Zacharowski K, Bornstein SR.

J Clin Endocrinol Metab. 2010 Dec;95(12):E421-9. doi: 10.1210/jc.2010-1100. Epub 2010 Sep 8.

PMID:
20826579
24.

Transcription factors Elk-1 and SRF are engaged in IL1-dependent regulation of ZC3H12A expression.

Kasza A, Wyrzykowska P, Horwacik I, Tymoszuk P, Mizgalska D, Palmer K, Rokita H, Sharrocks AD, Jura J.

BMC Mol Biol. 2010 Feb 6;11:14. doi: 10.1186/1471-2199-11-14.

25.

[Degradation of eukaryotic transcripts. Role and regulation of tristetraprolin activity].

Balwierz AK, Tymoszuk P, Kasza A.

Postepy Biochem. 2009;55(3):290-8. Review. Polish.

PMID:
19928585

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