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Items: 47

1.

Intratumor MAPK and PI3K signaling pathway heterogeneity in glioblastoma tissue correlates with CREB signaling and distinct target gene signatures.

Daniel PM, Filiz G, Tymms MJ, Ramsay RG, Kaye AH, Stylli SS, Mantamadiotis T.

Exp Mol Pathol. 2018 Aug;105(1):23-31. doi: 10.1016/j.yexmp.2018.05.009. Epub 2018 May 28.

PMID:
29852183
2.

Xenome--a tool for classifying reads from xenograft samples.

Conway T, Wazny J, Bromage A, Tymms M, Sooraj D, Williams ED, Beresford-Smith B.

Bioinformatics. 2012 Jun 15;28(12):i172-8. doi: 10.1093/bioinformatics/bts236.

3.

G2/M checkpoint gene expression in developing germ cells.

Hasthorpe S, Tainton K, Peart M, Roeszler KN, Bell KM, Lusby PE, Hutson JM, Tymms MJ.

Mol Reprod Dev. 2007 May;74(5):531-8.

PMID:
17290426
4.

The chromosome 21 transcription factor ETS2 transactivates the beta-APP promoter: implications for Down syndrome.

Wolvetang EW, Bradfield OM, Tymms M, Zavarsek S, Hatzistavrou T, Kola I, Hertzog PJ.

Biochim Biophys Acta. 2003 Jul 28;1628(2):105-10.

PMID:
12890557
5.
6.

Expression of the ETS transcription factor ELF3 in the retinal pigment epithelium.

Jobling AI, Fang Z, Koleski D, Tymms MJ.

Invest Ophthalmol Vis Sci. 2002 Nov;43(11):3530-7.

PMID:
12407165
7.

Human aminopeptidase B (rnpep) on chromosome 1q32.2: complementary DNA, genomic structure and expression.

Piesse C, Tymms M, Garrafa E, Gouzy C, Lacasa M, Cadel S, Cohen P, Foulon T.

Gene. 2002 Jun 12;292(1-2):129-40.

PMID:
12119107
8.

The Elf group of Ets-related transcription factors. ELF3 and ELF5.

Thomas RS, Ng AN, Zhou J, Tymms MJ, Doppler W, Kola I.

Adv Exp Med Biol. 2000;480:123-8. Review. No abstract available.

PMID:
10959418
9.

In vitro promoter analysis using nuclear extracts and G-free cassette vectors.

Tymms MJ.

Methods Mol Biol. 2000;130:247-56. Review. No abstract available.

PMID:
10589436
11.

The role of Ets-1 in mast cell granulocyte-macrophage colony-stimulating factor expression and activation.

McKinlay LH, Tymms MJ, Thomas RS, Seth A, Hasthorpe S, Hertzog PJ, Kola I.

J Immunol. 1998 Oct 15;161(8):4098-105.

12.

A novel epithelial-expressed ETS gene, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer.

Tymms MJ, Ng AY, Thomas RS, Schutte BC, Zhou J, Eyre HJ, Sutherland GR, Seth A, Rosenberg M, Papas T, Debouck C, Kola I.

Oncogene. 1997 Nov 13;15(20):2449-62.

13.
14.

ETS1, NFkappaB and AP1 synergistically transactivate the human GM-CSF promoter.

Thomas RS, Tymms MJ, McKinlay LH, Shannon MF, Seth A, Kola I.

Oncogene. 1997 Jun 12;14(23):2845-55.

15.

Regulation of Pdha-2 expression is mediated by proximal promoter sequences and CpG methylation.

Iannello RC, Young J, Sumarsono S, Tymms MJ, Dahl HH, Gould J, Hedger M, Kola I.

Mol Cell Biol. 1997 Feb;17(2):612-9.

16.

Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice.

Sumarsono SH, Wilson TJ, Tymms MJ, Venter DJ, Corrick CM, Kola R, Lahoud MH, Papas TS, Seth A, Kola I.

Nature. 1996 Feb 8;379(6565):534-7.

PMID:
8596630
17.

Construction of a mouse blastocyst cDNA library by PCR amplification from total RNA.

Corrick CM, Silvestro MJ, Lahoud MH, Allen GJ, Tymms MJ, Kola I.

Mol Reprod Dev. 1996 Jan;43(1):7-16.

PMID:
8720109
18.

A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses.

Hwang SY, Hertzog PJ, Holland KA, Sumarsono SH, Tymms MJ, Hamilton JA, Whitty G, Bertoncello I, Kola I.

Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):11284-8. Erratum in: Proc Natl Acad Sci U S A 1996 Apr 30;93(9):4519.

19.

ETS1 transactivates the human GM-CSF promoter in Jurkat T cells stimulated with PMA and ionomycin.

Thomas RS, Tymms MJ, Seth A, Shannon MF, Kola I.

Oncogene. 1995 Nov 16;11(10):2135-43.

PMID:
7478534
20.

Human ERG is a proto-oncogene with mitogenic and transforming activity.

Hart AH, Corrick CM, Tymms MJ, Hertzog PJ, Kola I.

Oncogene. 1995 Apr 6;10(7):1423-30.

PMID:
7731694
21.

Random amplified polymorphic DNA and plasmid analyses used in investigation of an outbreak of multiresistant Klebsiella pneumoniae.

Eisen D, Russell EG, Tymms M, Roper EJ, Grayson ML, Turnidge J.

J Clin Microbiol. 1995 Mar;33(3):713-7.

22.

A model for understanding gene regulation during spermatogenesis: the mouse testis Pdha-2 promoter.

Iannello RC, Young J, Sumarsono S, Tymms M, Kola I.

Reprod Fertil Dev. 1995;7(4):705-12. Review.

PMID:
8711207
23.

Structure-function studies based on in vitro expression.

Tymms MJ, Hertzog PJ.

Methods Mol Biol. 1995;37:317-35. No abstract available.

PMID:
7780513
24.

Quantitative measurement of mRNA using the RNase protection assay.

Tymms MJ.

Methods Mol Biol. 1995;37:31-46. No abstract available.

PMID:
7780512
25.

Regulation of gene expression by transcription factors Ets-1 and Ets-2.

Tymms MJ, Kola I.

Mol Reprod Dev. 1994 Oct;39(2):208-14. Review.

PMID:
7826624
26.
27.
28.

Mouse testis Pdha-2 promoter upstream sequences confer tissue-and temporal-specific activity in transgenic mice.

Iannello RC, Young JC, Sumarsono S, Tymms MJ, Kola I.

Reprod Fertil Dev. 1994;6(5):599-604.

PMID:
7569039
29.
30.

Influence of nucleotides flanking the ggaa core sequence on ets1 and ets2 DNA-binding activity and the mechanism of ets1 autoregulation.

Ascione R, Thompson D, Thomas R, Panayiotakis A, Ramsay R, Tymms M, Kola I, Seth A.

Int J Oncol. 1992 Nov;1(6):631-7.

PMID:
21584592
32.

Localization of four human chromosome 21 genes--SOD1, ETS2, IFNAR, and CBR--to two different chromosomes in the marsupial species Macropus eugenii.

Brookes S, Maccarone P, de Haan JB, Tymms M, Forrest GL, Graves JA, Kola I.

Cytogenet Cell Genet. 1992;61(1):25-8.

PMID:
1380419
33.

Universal antibodies to human interferon-alpha subtypes--the production of antipeptide antibodies to conserved regions of interferon-alpha.

Sattayasai N, McMullen GL, Marzuki S, Tribbick G, Geysen HM, Tymms MJ, Linnane AW.

J Interferon Res. 1991 Feb;11(1):41-8.

PMID:
1709418
34.

Structure-function studies of human interferons-alpha: enhanced activity on human and murine cells.

Cheetham BF, McInnes B, Mantamadiotis T, Murray PJ, Alin P, Bourke P, Linnane AW, Tymms MJ.

Antiviral Res. 1991 Jan;15(1):27-39.

PMID:
1903622
35.

Pharmacokinetics, tissue distribution, and cell localization of [35S]methionine-labeled recombinant human and murine alpha interferons in mice.

Johns TG, Kerry JA, Veitch BA, Mackay IR, Tutton PJ, Tymms MJ, Cheetham BF, Hertzog PJ, Linnane AW.

Cancer Res. 1990 Aug 1;50(15):4718-23.

36.

Structure-function studies of interferon-alpha based on random mutagenesis and expression in vitro.

Tymms MJ, McInnes B, Alin P, Linnane AW, Cheetham BF.

Genet Anal Tech Appl. 1990 May;7(3):53-63.

PMID:
1970261
37.

Comparison of augmentation of human natural killer cell cytotoxicity by interferon-alpha subtypes.

Verhagen A, Mackay IR, Rowley M, Tymms M.

Nat Immun Cell Growth Regul. 1990;9(5):325-33.

PMID:
2077397
38.

Functional significance of amino acid residues within conserved hydrophilic regions in human interferons-alpha.

Tymms MJ, McInnes B, Waine GJ, Cheetham BF, Linnane AW.

Antiviral Res. 1989 Aug;12(1):37-47.

PMID:
2688550
39.

Structure-function studies of interferons-alpha: amino acid substitutions at the conserved residue tyrosine 123 in human interferon-alpha 1.

McInnes B, Chambers PJ, Cheetham BF, Beilharz MW, Tymms MJ.

J Interferon Res. 1989 Jun;9(3):305-14.

PMID:
2526185
40.

Amino acid substitutions which alter the antiviral activity of human interferon-alpha 1 on mouse cells.

Beilharz MW, Tymms MJ, Chambers PJ, McInnes B, Pitha-Rowe PM, Linnane AW.

J Interferon Res. 1988 Dec;8(6):779-82.

PMID:
3148007
41.

Conserved amino acid residues arginine 33 and tyrosine 123 are critical for the antiviral activity of murine interferon-alpha 1.

Kerry JA, Tymms MJ, Linnane AW.

Biochem Biophys Res Commun. 1988 Sep 15;155(2):714-9.

PMID:
3421963
42.
43.

Antiviral and antiproliferative activities of interferon-alpha 1: the role of cysteine residues.

Beilharz MW, Nisbet IT, Tymms MJ, Hertzog PJ, Linnane AW.

J Interferon Res. 1986 Dec;6(6):677-85.

PMID:
3572088
44.

Single amino acid substitutions at conserved residues of human interferon-alpha can effect antiviral specific activity.

Nisbet IT, Beilharz MW, Hertzog PJ, Tymms MJ, Linnane AW.

Biochem Int. 1985 Sep;11(3):301-9.

PMID:
3904757
45.
46.

Plastid-DNA levels in the different tissues of potato.

Scott NS, Tymms MJ, Possingham JV.

Planta. 1984 Jan;161(1):12-9. doi: 10.1007/BF00951454.

PMID:
24253550
47.

DNA Content of Beta vulgaris Chloroplasts during Leaf Cell Expansion.

Tymms MJ, Scott NS, Possingham JV.

Plant Physiol. 1983 Apr;71(4):785-8.

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