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Eleven High-Quality Reference Genome Sequences and 360 Draft Assemblies of Shiga Toxin-Producing Escherichia coli Isolates from Human, Food, Animal, and Environmental Sources in Canada.

Tyson S, Peterson CL, Olson A, Tyler S, Knox N, Griffiths E, Dooley D, Hsiao W, Cabral J, Johnson RP, Laing C, Gannon V, Lynch T, Van Domselaar G, Brinkman F, Graham M.

Microbiol Resour Announc. 2019 Oct 10;8(41). pii: e00625-19. doi: 10.1128/MRA.00625-19.


Leveraging -omics for asthma endotyping.

Tyler SR, Bunyavanich S.

J Allergy Clin Immunol. 2019 Jul;144(1):13-23. doi: 10.1016/j.jaci.2019.05.015. Review.


Prolonged Neuromodulation of Cortical Networks Following Low-Frequency rTMS and Its Potential for Clinical Interventions.

Edwards G, Agosta S, Herpich F, Contò F, Parrott D, Tyler S, Grossman ED, Battelli L.

Front Psychol. 2019 Mar 12;10:529. doi: 10.3389/fpsyg.2019.00529. eCollection 2019.


Otoscopy and aural cytological findings in a population of rescue cats and cases in a referral small animal hospital in England and Wales.

Tyler S, Swales N, Foster AP, Knowles TG, Barnard N.

J Feline Med Surg. 2019 Mar 18:1098612X19834969. doi: 10.1177/1098612X19834969. [Epub ahead of print]


Highly Efficient Transgenesis in Ferrets Using CRISPR/Cas9-Mediated Homology-Independent Insertion at the ROSA26 Locus.

Yu M, Sun X, Tyler SR, Liang B, Swatek AM, Lynch TJ, He N, Yuan F, Feng Z, Rotti PG, Choi SH, Shahin W, Liu X, Yan Z, Engelhardt JF.

Sci Rep. 2019 Feb 13;9(1):1971. doi: 10.1038/s41598-018-37192-4.


PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq.

Tyler SR, Rotti PG, Sun X, Yi Y, Xie W, Winter MC, Flamme-Wiese MJ, Tucker BA, Mullins RF, Norris AW, Engelhardt JF.

Cell Rep. 2019 Feb 12;26(7):1951-1964.e8. doi: 10.1016/j.celrep.2019.01.063.


A revision of the new genus Amiga Nakahara, Willmott & Espeland, gen. n., described for Papilioarnaca Fabricius, 1776 (Lepidoptera, Nymphalidae, Satyrinae).

Nakahara S, Lamas G, Tyler S, Marín MA, Huertas B, Willmott KR, Mielke OHH, Espeland M.

Zookeys. 2019 Jan 31;(821):85-152. doi: 10.3897/zookeys.821.31782. eCollection 2019.


Shared genome analyses of notable listeriosis outbreaks, highlighting the critical importance of epidemiological evidence, input datasets and interpretation criteria.

Reimer A, Weedmark K, Petkau A, Peterson CL, Walker M, Knox N, Kent H, Mabon P, Berry C, Tyler S, Tschetter L, Jerome M, Allen V, Hoang L, Bekal S, Clark C, Nadon C, Van Domselaar G, Pagotto F, Graham M, Farber J, Gilmour M.

Microb Genom. 2019 Jan;5(1). doi: 10.1099/mgen.0.000237. Epub 2019 Jan 16.


In Reply to Daugherty and Lawrence.

Tyler S, Truong PT.

Int J Radiat Oncol Biol Phys. 2019 Jan 1;103(1):285. doi: 10.1016/j.ijrobp.2018.09.007. Epub 2018 Dec 12. No abstract available.


Whole genome sequencing and phylogenetic analysis of strains of the agent of Lyme disease Borrelia burgdorferi from Canadian emergence zones.

Tyler S, Tyson S, Dibernardo A, Drebot M, Feil EJ, Graham M, Knox NC, Lindsay LR, Margos G, Mechai S, Van Domselaar G, Thorpe HA, Ogden NH.

Sci Rep. 2018 Jul 12;8(1):10552. doi: 10.1038/s41598-018-28908-7.


Owner-reported flea treatment measures and skin disease in cats.

Tyler S, Roberts C, Foster A, Barnard N, Murray JK.

J Feline Med Surg. 2019 Apr;21(4):282-285. doi: 10.1177/1098612X18773911. Epub 2018 May 23.


Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium.

Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, Mou H, Herring BP, Thorne PS, Rajagopal J, Yeaman C, Parekh KR, Engelhardt JF.

Cell Stem Cell. 2018 May 3;22(5):779. doi: 10.1016/j.stem.2018.04.007. No abstract available.


Close Margins Less Than 2 mm Are Not Associated With Higher Risks of 10-Year Local Recurrence and Breast Cancer Mortality Compared With Negative Margins in Women Treated With Breast-Conserving Therapy.

Tyler S, Truong PT, Lesperance M, Nichol A, Baliski C, Warburton R, Tyldesley S.

Int J Radiat Oncol Biol Phys. 2018 Jul 1;101(3):661-670. doi: 10.1016/j.ijrobp.2018.03.005. Epub 2018 Mar 13.


Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium.

Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, Mou H, Herring BP, Thorne PS, Rajagopal J, Yeaman C, Parekh KR, Engelhardt JF.

Cell Stem Cell. 2018 May 3;22(5):653-667.e5. doi: 10.1016/j.stem.2018.03.017. Epub 2018 Apr 12. Erratum in: Cell Stem Cell. 2018 May 3;22(5):779.


Whole genome typing of the recently emerged Canadian serogroup W Neisseria meningitidis sequence type 11 clonal complex isolates associated with invasive meningococcal disease.

Tsang RSW, Ahmad T, Tyler S, Lefebvre B, Deeks SL, Gilca R, Hoang L, Tyrrell G, Van Caeseele P, Van Domselaar G, Jamieson FB.

Int J Infect Dis. 2018 Apr;69:55-62. doi: 10.1016/j.ijid.2018.01.019. Epub 2018 Feb 4.


Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets.

Rotti PG, Xie W, Poudel A, Yi Y, Sun X, Tyler SR, Uc A, Norris AW, Hara M, Engelhardt JF, Gibson-Corley KN.

Am J Pathol. 2018 Apr;188(4):876-890. doi: 10.1016/j.ajpath.2017.12.015. Epub 2018 Jan 31.


Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR-Knockout Ferrets.

Rosen BH, Evans TIA, Moll SR, Gray JS, Liang B, Sun X, Zhang Y, Jensen-Cody CW, Swatek AM, Zhou W, He N, Rotti PG, Tyler SR, Keiser NW, Anderson PJ, Brooks L, Li Y, Pope RM, Rajput M, Hoffman EA, Wang K, Harris JK, Parekh KR, Gibson-Corley KN, Engelhardt JF.

Am J Respir Crit Care Med. 2018 May 15;197(10):1308-1318. doi: 10.1164/rccm.201708-1616OC.


Rapid Improvement on a Temporal Attention Task within a Single Session of High-frequency Transcranial Random Noise Stimulation.

Tyler SC, Contò F, Battelli L.

J Cogn Neurosci. 2018 May;30(5):656-666. doi: 10.1162/jocn_a_01235. Epub 2018 Jan 11.


Depletion of Airway Submucosal Glands and TP63+KRT5+ Basal Cells in Obliterative Bronchiolitis.

Swatek AM, Lynch TJ, Crooke AK, Anderson PJ, Tyler SR, Brooks L, Ivanovic M, Klesney-Tait JA, Eberlein M, Pena T, Meyerholz DK, Engelhardt JF, Parekh KR.

Am J Respir Crit Care Med. 2018 Apr 15;197(8):1045-1057. doi: 10.1164/rccm.201707-1368OC.


Real-Time Monitoring of Insulin Using a Graphene Field-Effect Transistor Aptameric Nanosensor.

Hao Z, Zhu Y, Wang X, Rotti PG, DiMarco C, Tyler SR, Zhao X, Engelhardt JF, Hone J, Lin Q.

ACS Appl Mater Interfaces. 2017 Aug 23;9(33):27504-27511. doi: 10.1021/acsami.7b07684. Epub 2017 Aug 11.


Nickel Complexes of C-Substituted Cyclams and Their Activity for CO2 and H+ Reduction.

Cook TD, Tyler SF, McGuire CM, Zeller M, Fanwick PE, Evans DH, Peters DG, Ren T.

ACS Omega. 2017 Jul 26;2(7):3966-3976. doi: 10.1021/acsomega.7b00714. eCollection 2017 Jul 31.


The Pivotal Role of the Right Parietal Lobe in Temporal Attention.

Agosta S, Magnago D, Tyler S, Grossman E, Galante E, Ferraro F, Mazzini N, Miceli G, Battelli L.

J Cogn Neurosci. 2017 May;29(5):805-815. doi: 10.1162/jocn_a_01086. Epub 2016 Dec 19.


Network Connectivity of the Right STS in Three Social Perception Localizers.

Dasgupta S, Tyler SC, Wicks J, Srinivasan R, Grossman ED.

J Cogn Neurosci. 2017 Feb;29(2):221-234. doi: 10.1162/jocn_a_01054. Epub 2016 Oct 19.


Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors.

Ortiz DF, Lansing JC, Rutitzky L, Kurtagic E, Prod'homme T, Choudhury A, Washburn N, Bhatnagar N, Beneduce C, Holte K, Prenovitz R, Child M, Killough J, Tyler S, Brown J, Nguyen S, Schwab I, Hains M, Meccariello R, Markowitz L, Wang J, Zouaoui R, Simpson A, Schultes B, Capila I, Ling L, Nimmerjahn F, Manning AM, Bosques CJ.

Sci Transl Med. 2016 Nov 16;8(365):365ra158.


Use of Distributed Temperature Sensing Technology to Characterize Fire Behavior.

Cram D, Hatch CE, Tyler S, Ochoa C.

Sensors (Basel). 2016 Oct 17;16(10). pii: E1712.


c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer.

Maina PK, Shao P, Liu Q, Fazli L, Tyler S, Nasir M, Dong X, Qi HH.

Oncotarget. 2016 Nov 15;7(46):75585-75602. doi: 10.18632/oncotarget.12310.


Cr(III)-HMC (HMC = 5,5,7,12,12,14-Hexamethyl-1,4,8,11-tetraazacyclotetradecane) Alkynyl Complexes: Preparation and Emission Properties.

Tyler SF, Judkins EC, Song Y, Cao F, McMillin DR, Fanwick PE, Ren T.

Inorg Chem. 2016 Sep 6;55(17):8736-43. doi: 10.1021/acs.inorgchem.6b01285. Epub 2016 Aug 16.


One-Visit Behavioral Intervention for Older Primary Care Patients with Mild to Moderate Depressive Symptoms.

Gum AM, Schonfeld L, Tyler S, Fishleder S, Guerra L.

South Med J. 2016 Aug;109(8):442-7. doi: 10.14423/SMJ.0000000000000497.


Wnt Signaling Regulates Airway Epithelial Stem Cells in Adult Murine Submucosal Glands.

Lynch TJ, Anderson PJ, Xie W, Crooke AK, Liu X, Tyler SR, Luo M, Kusner DM, Zhang Y, Neff T, Burnette DC, Walters KS, Goodheart MJ, Parekh KR, Engelhardt JF.

Stem Cells. 2016 Nov;34(11):2758-2771. doi: 10.1002/stem.2443. Epub 2016 Jul 11.


Phenotypic H-Antigen Typing by Mass Spectrometry Combined with Genetic Typing of H Antigens, O Antigens, and Toxins by Whole-Genome Sequencing Enhances Identification of Escherichia coli Isolates.

Cheng K, Chui H, Domish L, Sloan A, Hernandez D, McCorrister S, Robinson A, Walker M, Peterson LA, Majcher M, Ratnam S, Haldane DJ, Bekal S, Wylie J, Chui L, Tyler S, Xu B, Reimer A, Nadon C, Knox JD, Wang G.

J Clin Microbiol. 2016 Aug;54(8):2162-8. doi: 10.1128/JCM.00422-16. Epub 2016 Jun 15.


A Study of the Infant Nasal Microbiome Development over the First Year of Life and in Relation to Their Primary Adult Caregivers Using cpn60 Universal Target (UT) as a Phylogenetic Marker.

Peterson SW, Knox NC, Golding GR, Tyler SD, Tyler AD, Mabon P, Embree JE, Fleming F, Fanella S, Van Domselaar G, Mulvey MR, Graham MR.

PLoS One. 2016 Mar 28;11(3):e0152493. doi: 10.1371/journal.pone.0152493. eCollection 2016.


The outlook for 2016.

Tyler S.

Midwives. 2015 Winter;18:5. No abstract available.


Timing and location of reproduction in African waterfowl: an overview of >100 years of nest records.

Cumming GS, Harebottle DM, Mundava J, Otieno N, Tyler SJ.

Ecol Evol. 2016 Jan 18;6(3):631-46. doi: 10.1002/ece3.1853. eCollection 2016 Feb.


A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling.

Yi Y, Sun X, Gibson-Corley K, Xie W, Liang B, He N, Tyler SR, Uc A, Philipson LH, Wang K, Hara M, Ode KL, Norris AW, Engelhardt JF.

Endocrinology. 2016 May;157(5):1852-65. doi: 10.1210/en.2015-1935. Epub 2016 Feb 10.


Interpreting Variations in Groundwater Flows from Repeated Distributed Thermal Perturbation Tests.

Hausner MB, Kryder L, Klenke J, Reinke R, Tyler SW.

Ground Water. 2016 Jul;54(4):559-68. doi: 10.1111/gwat.12393. Epub 2015 Dec 29.


Two new acoels (Acoelomorpha) of the genus Haplogonaria from the northwest Atlantic.

Hooge MD, Tyler S.

Zootaxa. 2015 Sep 7;4013(1):111-9. doi: 10.11646/zootaxa.4013.1.8.


High geothermal heat flux measured below the West Antarctic Ice Sheet.

Fisher AT, Mankoff KD, Tulaczyk SM, Tyler SW, Foley N; WISSARD Science Team.

Sci Adv. 2015 Jul 10;1(6):e1500093. doi: 10.1126/sciadv.1500093. eCollection 2015 Jul.


Drinking behavior among older adults in a planned retirement community: results from The Villages survey.

Fishleder S, Schonfeld L, Corvin J, Tyler S, VandeWeerd C.

Int J Geriatr Psychiatry. 2016 May;31(5):536-43. doi: 10.1002/gps.4359. Epub 2015 Oct 5.


Turning a New Leaf on Metal-TMC Chemistry: Ni(II)(TMC) Acetylides.

Tyler SF, Natoli SN, Vlaisavljevich B, Fanwick PE, Ren T.

Inorg Chem. 2015 Oct 19;54(20):10058-64. doi: 10.1021/acs.inorgchem.5b01883. Epub 2015 Sep 28.


Glandular Proteome Identifies Antiprotease Cystatin C as a Critical Modulator of Airway Hydration and Clearance.

Evans TI, Joo NS, Keiser NW, Yan Z, Tyler SR, Xie W, Zhang Y, Hsiao JJ, Cho HJ, Wright ME, Wine JJ, Engelhardt JF.

Am J Respir Cell Mol Biol. 2016 Apr;54(4):469-81. doi: 10.1165/rcmb.2015-0090OC.


Chlamydia trachomatis virulence factor CT135 is stable in vivo but highly polymorphic in vitro.

Bonner C, Caldwell HD, Carlson JH, Graham MR, Kari L, Sturdevant GL, Tyler S, Zetner A, McClarty G.

Pathog Dis. 2015 Aug;73(6):ftv043. doi: 10.1093/femspd/ftv043. Epub 2015 Jun 24.


Identification of a novel Afipia species isolated from an Indian flying fox.

Pickering BS, Tyler S, Smith G, Burton L, Li M, Dallaire A, Weingartl H.

PLoS One. 2015 Apr 15;10(4):e0121274. doi: 10.1371/journal.pone.0121274. eCollection 2015.


Functional connectivity of parietal cortex during temporal selective attention.

Tyler SC, Dasgupta S, Agosta S, Battelli L, Grossman ED.

Cortex. 2015 Apr;65:195-207. doi: 10.1016/j.cortex.2015.01.015. Epub 2015 Feb 9.


Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity.

Washburn N, Schwab I, Ortiz D, Bhatnagar N, Lansing JC, Medeiros A, Tyler S, Mekala D, Cochran E, Sarvaiya H, Garofalo K, Meccariello R, Meador JW 3rd, Rutitzky L, Schultes BC, Ling L, Avery W, Nimmerjahn F, Manning AM, Kaundinya GV, Bosques CJ.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1297-306. doi: 10.1073/pnas.1422481112. Epub 2015 Mar 2. Erratum in: Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4339.


'What matters to graduates': An evaluation of a structured clinical support program for newly graduated nurses.

Henderson A, Ossenberg C, Tyler S.

Nurse Educ Pract. 2015 May;15(3):225-31. doi: 10.1016/j.nepr.2015.01.009. Epub 2015 Jan 26.


Neuregulin 1 expression is a predictive biomarker for response to AV-203, an ERBB3 inhibitory antibody, in human tumor models.

Meetze K, Vincent S, Tyler S, Mazsa EK, Delpero AR, Bottega S, McIntosh D, Nicoletti R, Winston WM, Weiler S, Feng B, Gyuris J, Weng Z.

Clin Cancer Res. 2015 Mar 1;21(5):1106-14. doi: 10.1158/1078-0432.CCR-14-2407. Epub 2014 Dec 26.


Design and nuclear magnetic resonance (NMR) structure determination of the second extracellular immunoglobulin tyrosine kinase A (TrkAIg2) domain construct for binding site elucidation in drug discovery.

Shoemark DK, Williams C, Fahey MS, Watson JJ, Tyler SJ, Scoltock SJ, Ellis RZ, Wickenden E, Burton AJ, Hemmings JL, Bailey CD, Dawbarn D, Jane DE, Willis CL, Sessions RB, Allen SJ, Crump MP.

J Med Chem. 2015 Jan 22;58(2):767-77. doi: 10.1021/jm501307e. Epub 2014 Dec 22.


The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease.

Peng X, Alföldi J, Gori K, Eisfeld AJ, Tyler SR, Tisoncik-Go J, Brawand D, Law GL, Skunca N, Hatta M, Gasper DJ, Kelly SM, Chang J, Thomas MJ, Johnson J, Berlin AM, Lara M, Russell P, Swofford R, Turner-Maier J, Young S, Hourlier T, Aken B, Searle S, Sun X, Yi Y, Suresh M, Tumpey TM, Siepel A, Wisely SM, Dessimoz C, Kawaoka Y, Birren BW, Lindblad-Toh K, Di Palma F, Engelhardt JF, Palermo RE, Katze MG.

Nat Biotechnol. 2014 Dec;32(12):1250-5. doi: 10.1038/nbt.3079. Epub 2014 Nov 17.


Defective innate immunity and hyperinflammation in newborn cystic fibrosis transmembrane conductance regulator-knockout ferret lungs.

Keiser NW, Birket SE, Evans IA, Tyler SR, Crooke AK, Sun X, Zhou W, Nellis JR, Stroebele EK, Chu KK, Tearney GJ, Stevens MJ, Harris JK, Rowe SM, Engelhardt JF.

Am J Respir Cell Mol Biol. 2015 Jun;52(6):683-94. doi: 10.1165/rcmb.2014-0250OC.

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