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Youth Needs at Intake into Trauma-Informed Group Homes and Response to Services: An Examination of Trauma Exposure, Symptoms, and Clinical Impression.

Tyler PM, Patwardan I, Ringle JL, Chmelka MB, Mason WA.

Am J Community Psychol. 2019 Aug 1. doi: 10.1002/ajcp.12364. [Epub ahead of print]


Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation.

Hippensteel JA, Uchimido R, Tyler PD, Burke RC, Han X, Zhang F, McMurtry SA, Colbert JF, Lindsell CJ, Angus DC, Kellum JA, Yealy DM, Linhardt RJ, Shapiro NI, Schmidt EP.

Crit Care. 2019 Jul 23;23(1):259. doi: 10.1186/s13054-019-2534-2.


Estimation of Actual and Ideal Bodyweight Using Morphometric Measurements of Miniature, Saddle-Type, and Thoroughbred Horses.

Catalano DN, Coleman RJ, Hathaway MR, Neu AE, Wagner EL, Tyler PJ, McCue ME, Martinson KL.

J Equine Vet Sci. 2019 Jul;78:117-122. doi: 10.1016/j.jevs.2019.04.008. Epub 2019 May 13.


Threat Responsiveness as a Function of Cannabis and Alcohol Use Disorder Severity.

Blair RJR, White SF, Tyler PM, Johnson K, Lukoff J, Thornton LC, Leiker EK, Filbey F, Dobbertin M, Blair KS.

J Child Adolesc Psychopharmacol. 2019 Jun 6. doi: 10.1089/cap.2019.0004. [Epub ahead of print]


Association of Different Types of Childhood Maltreatment With Emotional Responding and Response Control Among Youths.

Blair KS, Aloi J, Crum K, Meffert H, White SF, Taylor BK, Leiker EK, Thornton LC, Tyler PM, Shah N, Johnson K, Abdel-Rahim H, Lukoff J, Dobbertin M, Pope K, Pollak S, Blair RJ.

JAMA Netw Open. 2019 May 3;2(5):e194604. doi: 10.1001/jamanetworkopen.2019.4604.


Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase.

Harijan RK, Hoff O, Ducati RG, Firestone RS, Hirsch BM, Evans GB, Schramm VL, Tyler PC.

J Med Chem. 2019 Apr 11;62(7):3286-3296. doi: 10.1021/acs.jmedchem.8b01642. Epub 2019 Mar 28.


Differential dysfunctions related to alcohol and cannabis use disorder symptoms in reward and error-processing neuro-circuitries in adolescents.

Aloi J, Meffert H, White SF, Blair KS, Hwang S, Tyler PM, Thornton LC, Crum KI, Adams KO, Killanin AD, Filbey F, Pope K, Blair RJR.

Dev Cogn Neurosci. 2019 Apr;36:100618. doi: 10.1016/j.dcn.2019.100618. Epub 2019 Jan 24.


Segregating sustained attention from response inhibition in ADHD: An fMRI study.

Hwang S, Meffert H, Parsley I, Tyler PM, Erway AK, Botkin ML, Pope K, Blair RJR.

Neuroimage Clin. 2019;21:101677. doi: 10.1016/j.nicl.2019.101677. Epub 2019 Jan 15.


Assessment of Intensive Care Unit Laboratory Values That Differ From Reference Ranges and Association With Patient Mortality and Length of Stay.

Tyler PD, Du H, Feng M, Bai R, Xu Z, Horowitz GL, Stone DJ, Celi LA.

JAMA Netw Open. 2018 Nov 2;1(7):e184521. doi: 10.1001/jamanetworkopen.2018.4521.


The transition to magic bullets - transition state analogue drug design.

Evans GB, Schramm VL, Tyler PC.

Medchemcomm. 2018 Aug 28;9(12):1983-1993. doi: 10.1039/c8md00372f. eCollection 2018 Dec 1. Review.


The Potential Role of Ultrasound in the Work-up of Appendicitis in the Emergency Department.

Tyler PD, Carey J, Stashko E, Levenson RB, Shapiro NI, Rosen CL.

J Emerg Med. 2019 Feb;56(2):191-196. doi: 10.1016/j.jemermed.2018.10.034. Epub 2018 Dec 26.


Using automated glycan assembly (AGA) for the practical synthesis of heparan sulfate oligosaccharide precursors.

Budhadev D, Saxby K, Walton J, Davies G, Tyler PC, Schwörer R, Fascione MA.

Org Biomol Chem. 2019 Feb 13;17(7):1817-1821. doi: 10.1039/c8ob02756k.


Dendrimer Heparan Sulfate Glycomimetics: Potent Heparanase Inhibitors for Anticancer Therapy.

Zubkova OV, Ahmed YA, Guimond SE, Noble SL, Miller JH, Alfred Smith RA, Nurcombe V, Tyler PC, Weissmann M, Vlodavsky I, Turnbull JE.

ACS Chem Biol. 2018 Dec 21;13(12):3236-3242. doi: 10.1021/acschembio.8b00909. Epub 2018 Nov 29.


A novel ceramic coating for reduced metal ion release in metal-on-metal hip surgery.

Blunn GW, Ferro De Godoy R, Meswania J, Briggs TWR, Tyler P, Hargunani R, Wilson H, Khan I, Marriott T, Coathup MJ.

J Biomed Mater Res B Appl Biomater. 2019 Aug;107(6):1760-1771. doi: 10.1002/jbm.b.34268. Epub 2018 Nov 17.


Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+ T Cell-Effector Responses.

Clancy-Thompson E, Devlin CA, Tyler PM, Servos MM, Ali LR, Ventre KS, Bhuiyan MA, Bruck PT, Birnbaum ME, Dougan SK.

Cancer Immunol Res. 2018 Dec;6(12):1524-1536. doi: 10.1158/2326-6066.CIR-18-0348. Epub 2018 Oct 23.


Transition-State Analogues of Campylobacter jejuni 5'-Methylthioadenosine Nucleosidase.

Ducati RG, Harijan RK, Cameron SA, Tyler PC, Evans GB, Schramm VL.

ACS Chem Biol. 2018 Nov 16;13(11):3173-3183. doi: 10.1021/acschembio.8b00781. Epub 2018 Oct 19.


The authors reply.

Tyler PD, Rush B, Celi LA.

Crit Care Med. 2018 Sep;46(9):e963-e964. doi: 10.1097/CCM.0000000000003243. No abstract available.


Adolescents show differential dysfunctions related to Alcohol and Cannabis Use Disorder severity in emotion and executive attention neuro-circuitries.

Aloi J, Blair KS, Crum KI, Meffert H, White SF, Tyler PM, Thornton LC, Mobley AM, Killanin AD, Adams KO, Filbey F, Pope K, Blair RJR.

Neuroimage Clin. 2018 Jun 5;19:782-792. doi: 10.1016/j.nicl.2018.06.005. eCollection 2018.


The authors reply.

Tyler PD, Rush B, Celi LA.

Crit Care Med. 2018 Jul;46(7):e730-e731. doi: 10.1097/CCM.0000000000003178. No abstract available.


Behind the scenes: A medical natural language processing project.

Wu JT, Dernoncourt F, Gehrmann S, Tyler PD, Moseley ET, Carlson ET, Grant DW, Li Y, Welt J, Celi LA.

Int J Med Inform. 2018 Apr;112:68-73. doi: 10.1016/j.ijmedinf.2017.12.003. Epub 2017 Dec 9.


Targeting Cytokine Therapy to the Pancreatic Tumor Microenvironment Using PD-L1-Specific VHHs.

Dougan M, Ingram JR, Jeong HJ, Mosaheb MM, Bruck PT, Ali L, Pishesha N, Blomberg O, Tyler PM, Servos MM, Rashidian M, Nguyen QD, von Andrian UH, Ploegh HL, Dougan SK.

Cancer Immunol Res. 2018 Apr;6(4):389-401. doi: 10.1158/2326-6066.CIR-17-0495. Epub 2018 Feb 19.


Comparing deep learning and concept extraction based methods for patient phenotyping from clinical narratives.

Gehrmann S, Dernoncourt F, Li Y, Carlson ET, Wu JT, Welt J, Foote J Jr, Moseley ET, Grant DW, Tyler PD, Celi LA.

PLoS One. 2018 Feb 15;13(2):e0192360. doi: 10.1371/journal.pone.0192360. eCollection 2018.


Applying a Cognitive Neuroscience Perspective to Disruptive Behavior Disorders: Implications for Schools.

Tyler PM, White SF, Thompson RW, Blair RJR.

Dev Neuropsychol. 2019 Jan-Feb;44(1):17-42. doi: 10.1080/87565641.2017.1334782. Epub 2018 Feb 12.


Moderation of prior exposure to trauma on the inverse relationship between callous-unemotional traits and amygdala responses to fearful expressions: an exploratory study.

Meffert H, Thornton LC, Tyler PM, Botkin ML, Erway AK, Kolli V, Pope K, White SF, Blair RJR.

Psychol Med. 2018 Nov;48(15):2541-2549. doi: 10.1017/S0033291718000156. Epub 2018 Feb 12.


A Framework for Tracking Former Patients in the Electronic Health Record Using an Educational Registry.

Brisson GE, Barnard C, Tyler PD, Liebovitz DM, Neely KJ.

J Gen Intern Med. 2018 Apr;33(4):563-566. doi: 10.1007/s11606-017-4278-5. Epub 2018 Jan 4.


Immucillins in Infectious Diseases.

Evans GB, Tyler PC, Schramm VL.

ACS Infect Dis. 2018 Feb 9;4(2):107-117. doi: 10.1021/acsinfecdis.7b00172. Epub 2017 Dec 5. Review.


Racial and Geographic Disparities in Interhospital ICU Transfers.

Tyler PD, Stone DJ, Geisler BP, McLennan S, Celi LA, Rush B.

Crit Care Med. 2018 Jan;46(1):e76-e80. doi: 10.1097/CCM.0000000000002776.


Outcomes of Ventilated Patients With Sepsis Who Undergo Interhospital Transfer: A Nationwide Linked Analysis.

Rush B, Tyler PD, Stone DJ, Geisler BP, Walley KR, Celi LA.

Crit Care Med. 2018 Jan;46(1):e81-e86. doi: 10.1097/CCM.0000000000002777.


Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase.

Moggré GJ, Poulin MB, Tyler PC, Schramm VL, Parker EJ.

ACS Chem Biol. 2017 Oct 20;12(10):2662-2670. doi: 10.1021/acschembio.7b00484. Epub 2017 Sep 19.


Transition State Analogue Inhibitors of 5'-Deoxyadenosine/5'-Methylthioadenosine Nucleosidase from Mycobacterium tuberculosis.

Namanja-Magliano HA, Evans GB, Harijan RK, Tyler PC, Schramm VL.

Biochemistry. 2017 Sep 26;56(38):5090-5098. doi: 10.1021/acs.biochem.7b00576. Epub 2017 Sep 7.


Tele-ICU Increases Interhospital Transfers: Does Big Brother Know Better?

Tyler PD, Celi LA.

Crit Care Med. 2017 Aug;45(8):1417-1419. doi: 10.1097/CCM.0000000000002510. No abstract available.


Mechanism-based inactivator of isocitrate lyases 1 and 2 from Mycobacterium tuberculosis.

Pham TV, Murkin AS, Moynihan MM, Harris L, Tyler PC, Shetty N, Sacchettini JC, Huang HL, Meek TD.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7617-7622. doi: 10.1073/pnas.1706134114. Epub 2017 Jul 5.


Monoclonal Invariant NKT (iNKT) Cell Mice Reveal a Role for Both Tissue of Origin and the TCR in Development of iNKT Functional Subsets.

Clancy-Thompson E, Chen GZ, Tyler PM, Servos MM, Barisa M, Brennan PJ, Ploegh HL, Dougan SK.

J Immunol. 2017 Jul 1;199(1):159-171. doi: 10.4049/jimmunol.1700214. Epub 2017 Jun 2.


Regulation of acetyl-CoA synthetase transcription by the CrbS/R two-component system is conserved in genetically diverse environmental pathogens.

Jacob K, Rasmussen A, Tyler P, Servos MM, Sylla M, Prado C, Daniele E, Sharp JS, Purdy AE.

PLoS One. 2017 May 18;12(5):e0177825. doi: 10.1371/journal.pone.0177825. eCollection 2017.


Comparative Phytochemical Analysis of Chinese and Bay Starvine (Schisandra spp.): Potential for Development as a New Dietary Supplement Ingredient.

Lyles JT, Tyler P, Bradbury EJ, Nelson K, Brown CF, Pierce ST, Quave CL.

J Diet Suppl. 2017 Nov 2;14(6):640-652. doi: 10.1080/19390211.2017.1304483. Epub 2017 Apr 6.


Carrots, Not Sticks: Adverse Impact and Wellness Programs.

Switzer FS 3rd, Cheung JH, Burns DK, Sinclair RR, Roth PL, Tyler P, McCubbin J.

J Occup Environ Med. 2017 Mar;59(3):250-255. doi: 10.1097/JOM.0000000000000940.


Clinical Dosing Regimen of Selinexor Maintains Normal Immune Homeostasis and T-cell Effector Function in Mice: Implications for Combination with Immunotherapy.

Tyler PM, Servos MM, de Vries RC, Klebanov B, Kashyap T, Sacham S, Landesman Y, Dougan M, Dougan SK.

Mol Cancer Ther. 2017 Mar;16(3):428-439. doi: 10.1158/1535-7163.MCT-16-0496. Epub 2017 Feb 1.


Anti-Acne Activity of Italian Medicinal Plants Used for Skin Infection.

Nelson K, Lyles JT, Li T, Saitta A, Addie-Noye E, Tyler P, Quave CL.

Front Pharmacol. 2016 Nov 10;7:425. eCollection 2016.


Oligonucleotide transition state analogues of saporin L3.

Mason JM, Yuan H, Evans GB, Tyler PC, Du Q, Schramm VL.

Eur J Med Chem. 2017 Feb 15;127:793-809. doi: 10.1016/j.ejmech.2016.10.059. Epub 2016 Oct 27.


Continuous Fluorescence Assays for Reactions Involving Adenine.

Firestone RS, Cameron SA, Tyler PC, Ducati RG, Spitz AZ, Schramm VL.

Anal Chem. 2016 Dec 6;88(23):11860-11867. Epub 2016 Nov 11.


Youth with substance abuse histories exhibit dysfunctional representation of expected value during a passive avoidance task.

White SF, Tyler P, Botkin ML, Erway AK, Thornton LC, Kolli V, Pope K, Meffert H, Blair RJ.

Psychiatry Res Neuroimaging. 2016 Nov 30;257:17-24. doi: 10.1016/j.pscychresns.2016.08.010. Epub 2016 Sep 21.


Medical Student Use of Electronic Health Records to Track Former Patients.

Brisson GE, Tyler PD.

JAMA Intern Med. 2016 Sep 1;176(9):1395-7. doi: 10.1001/jamainternmed.2016.3878. No abstract available.


Access to Prescription Opioids-Primum Non Nocere: A Teachable Moment.

Tyler PD, Larochelle MR, Mafi JN.

JAMA Intern Med. 2016 Sep 1;176(9):1251-2. doi: 10.1001/jamainternmed.2016.3926. No abstract available.


Characterization of CC-531 as a Rat Model of Colorectal Liver Metastases.

White SB, Procissi D, Chen J, Gogineni VR, Tyler P, Yang Y, Omary RA, Larson AC.

PLoS One. 2016 May 12;11(5):e0155334. doi: 10.1371/journal.pone.0155334. eCollection 2016.


Dysfunctional representation of expected value is associated with reinforcement-based decision-making deficits in adolescents with conduct problems.

White SF, Tyler PM, Erway AK, Botkin ML, Kolli V, Meffert H, Pope K, Blair JR.

J Child Psychol Psychiatry. 2016 Aug;57(8):938-46. doi: 10.1111/jcpp.12557. Epub 2016 Apr 8.


Connectivity in the cold: the comparative population genetics of vent-endemic fauna in the Scotia Sea, Southern Ocean.

Roterman CN, Copley JT, Linse KT, Tyler PA, Rogers AD.

Mol Ecol. 2016 Mar;25(5):1073-88. doi: 10.1111/mec.13541.


Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis.

Freitas EO, Nico D, Alves-Silva MV, Morrot A, Clinch K, Evans GB, Tyler PC, Schramm VL, Palatnik-de-Sousa CB.

PLoS Negl Trop Dis. 2015 Dec 23;9(12):e0004297. doi: 10.1371/journal.pntd.0004297. eCollection 2015 Dec.


Diagnostic and Therapeutic Nanoparticles in Cardiovascular Diseases.

Tyler PD, Kang PM.

Curr Pharm Des. 2015;21(42):6070-80. Review.


New Antibiotic Candidates against Helicobacter pylori.

Wang S, Cameron SA, Clinch K, Evans GB, Wu Z, Schramm VL, Tyler PC.

J Am Chem Soc. 2015 Nov 18;137(45):14275-80. doi: 10.1021/jacs.5b06110. Epub 2015 Nov 9.


Composition, sequencing and ion mobility mass spectrometry of heparan sulfate-like octasaccharide isomers differing in glucuronic and iduronic acid content.

Leary JA, Miller RL, Wei W, Schwörer R, Zubkova OV, Tyler PC, Turnbull JE.

Eur J Mass Spectrom (Chichester). 2015;21(3):245-54. doi: 10.1255/ejms.1337.


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