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Items: 1 to 50 of 209

1.

Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis.

Messacar K, Sillau S, Hopkins SE, Otten C, Wilson-Murphy M, Wong B, Santoro JD, Treister A, Bains HK, Torres A, Zabrocki L, Glanternik JR, Hurst AL, Martin JA, Schreiner T, Makhani N, DeBiasi RL, Kruer MC, Tremoulet AH, Van Haren K, Desai J, Benson LA, Gorman MP, Abzug MJ, Tyler KL, Dominguez SR.

Neurology. 2018 Nov 9. pii: 10.1212/WNL.0000000000006670. doi: 10.1212/WNL.0000000000006670. [Epub ahead of print]

PMID:
30413631
2.

Contemporary Circulating Enterovirus D68 Strains Have Acquired the Capacity for Viral Entry and Replication in Human Neuronal Cells.

Brown DM, Hixon AM, Oldfield LM, Zhang Y, Novotny M, Wang W, Das SR, Shabman RS, Tyler KL, Scheuermann RH.

MBio. 2018 Oct 16;9(5). pii: e01954-18. doi: 10.1128/mBio.01954-18.

3.

Acute Viral Encephalitis.

Tyler KL.

N Engl J Med. 2018 Aug 9;379(6):557-566. doi: 10.1056/NEJMra1708714. Review. No abstract available.

PMID:
30089069
4.

Pharmacologic Depletion of Microglia Increases Viral Load in the Brain and Enhances Mortality in Murine Models of Flavivirus-Induced Encephalitis.

Seitz S, Clarke P, Tyler KL.

J Virol. 2018 Jul 31;92(16). pii: e00525-18. doi: 10.1128/JVI.00525-18. Print 2018 Aug 15.

PMID:
29899084
5.

What's Next (Generation) for the Diagnosis of Chronic Meningitis?

Tyler KL.

JAMA Neurol. 2018 Aug 1;75(8):915-917. doi: 10.1001/jamaneurol.2018.0473. No abstract available.

PMID:
29710076
6.

Enterovirus D68 and acute flaccid myelitis-evaluating the evidence for causality.

Messacar K, Asturias EJ, Hixon AM, Van Leer-Buter C, Niesters HGM, Tyler KL, Abzug MJ, Dominguez SR.

Lancet Infect Dis. 2018 Aug;18(8):e239-e247. doi: 10.1016/S1473-3099(18)30094-X. Epub 2018 Feb 23. Review.

PMID:
29482893
7.

Encephalitis in US Children.

Messacar K, Fischer M, Dominguez SR, Tyler KL, Abzug MJ.

Infect Dis Clin North Am. 2018 Mar;32(1):145-162. doi: 10.1016/j.idc.2017.10.007. Epub 2017 Dec 8. Review.

PMID:
29224854
8.

Metagenomic Investigation of Idiopathic Meningoencephalomyelitis in Dogs.

Hoon-Hanks LL, McGrath S, Tyler KL, Owen C, Stenglein MD.

J Vet Intern Med. 2018 Jan;32(1):324-330. doi: 10.1111/jvim.14877. Epub 2017 Dec 2.

9.

An Overview of Yellow Fever Virus Disease.

McGuinness I, Beckham JD, Tyler KL, Pastula DM.

Neurohospitalist. 2017 Oct;7(4):157-158. doi: 10.1177/1941874417708129. Epub 2017 May 10. No abstract available.

10.

Evaluating Treatment Efficacy in a Mouse Model of Enterovirus D68-Associated Paralytic Myelitis.

Hixon AM, Clarke P, Tyler KL.

J Infect Dis. 2017 Dec 5;216(10):1245-1253. doi: 10.1093/infdis/jix468.

PMID:
28968718
11.

Minocycline Has Anti-inflammatory Effects and Reduces Cytotoxicity in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection.

Quick ED, Seitz S, Clarke P, Tyler KL.

J Virol. 2017 Oct 27;91(22). pii: e00569-17. doi: 10.1128/JVI.00569-17. Print 2017 Nov 15.

12.

The Expanding Spectrum of Zika Virus Infections of the Nervous System.

Tyler KL, Roos KL.

JAMA Neurol. 2017 Oct 1;74(10):1169-1171. doi: 10.1001/jamaneurol.2017.1471. No abstract available.

PMID:
28806454
13.

Outcomes of Colorado children with acute flaccid myelitis at 1 year.

Martin JA, Messacar K, Yang ML, Maloney JA, Lindwall J, Carry T, Kenyon P, Sillau SH, Oleszek J, Tyler KL, Dominguez SR, Schreiner TL.

Neurology. 2017 Jul 11;89(2):129-137. doi: 10.1212/WNL.0000000000004081. Epub 2017 Jun 14.

14.

Molecular mechanisms of neuroinflammation and injury during acute viral encephalitis.

Shives KD, Tyler KL, Beckham JD.

J Neuroimmunol. 2017 Jul 15;308:102-111. doi: 10.1016/j.jneuroim.2017.03.006. Epub 2017 Mar 11. Review.

PMID:
28291542
15.

A mouse model of paralytic myelitis caused by enterovirus D68.

Hixon AM, Yu G, Leser JS, Yagi S, Clarke P, Chiu CY, Tyler KL.

PLoS Pathog. 2017 Feb 23;13(2):e1006199. doi: 10.1371/journal.ppat.1006199. eCollection 2017 Feb.

16.

To PLEX or not to PLEX in natalizumab-associated PML.

Tyler KL, Vollmer TL.

Neurology. 2017 Mar 21;88(12):1108-1109. doi: 10.1212/WNL.0000000000003747. Epub 2017 Feb 22. No abstract available.

PMID:
28228561
17.

Zika Virus Disease and Associated Neurologic Complications.

Duca LM, Beckham JD, Tyler KL, Pastula DM.

Curr Infect Dis Rep. 2017 Jan;19(1):4. doi: 10.1007/s11908-017-0557-x. Review.

PMID:
28220392
18.

Zika virus disease for neurologists.

Smith DE, Beckham JD, Tyler KL, Pastula DM.

Neurol Clin Pract. 2016 Dec;6(6):515-522. doi: 10.1212/CPJ.0000000000000307. Review.

19.

Zika Virus Disease for the Neurointensivist.

Pastula DM, Durrant JC, Smith DE, Beckham JD, Tyler KL.

Neurocrit Care. 2017 Jun;26(3):457-463. doi: 10.1007/s12028-016-0333-z. Review.

PMID:
27995511
20.

Hepatitis E Virus and Guillain-Barré Syndrome.

Tyler KL, Pastula DM.

JAMA Neurol. 2017 Jan 1;74(1):13-15. doi: 10.1001/jamaneurol.2016.3651. No abstract available.

PMID:
27820625
21.

Emerging Diagnostic and Therapeutic Tools for Central Nervous System Infections.

Wilson M, Tyler KL.

JAMA Neurol. 2016 Dec 1;73(12):1389-1390. doi: 10.1001/jamaneurol.2016.3617. No abstract available.

22.

Zika virus: An emergent neuropathological agent.

White MK, Wollebo HS, David Beckham J, Tyler KL, Khalili K.

Ann Neurol. 2016 Oct;80(4):479-89. doi: 10.1002/ana.24748. Epub 2016 Aug 10. Review.

23.

Acute flaccid myelitis: A clinical review of US cases 2012-2015.

Messacar K, Schreiner TL, Van Haren K, Yang M, Glaser CA, Tyler KL, Dominguez SR.

Ann Neurol. 2016 Sep;80(3):326-38. doi: 10.1002/ana.24730. Epub 2016 Aug 4. Review.

24.

An Overview of Zika Virus Disease.

Pastula DM, Smith DE, Beckham JD, Tyler KL.

Neurohospitalist. 2016 Jul;6(3):93-4. doi: 10.1177/1941874416637409. Epub 2016 Mar 24. No abstract available.

25.

A complement-microglial axis drives synapse loss during virus-induced memory impairment.

Vasek MJ, Garber C, Dorsey D, Durrant DM, Bollman B, Soung A, Yu J, Perez-Torres C, Frouin A, Wilton DK, Funk K, DeMasters BK, Jiang X, Bowen JR, Mennerick S, Robinson JK, Garbow JR, Tyler KL, Suthar MS, Schmidt RE, Stevens B, Klein RS.

Nature. 2016 Jun 23;534(7608):538-43. doi: 10.1038/nature18283.

26.

Mitochondrial p53 Contributes to Reovirus-Induced Neuronal Apoptosis and Central Nervous System Injury in a Mouse Model of Viral Encephalitis.

Zhuang Y, Berens-Norman HM, Leser JS, Clarke P, Tyler KL.

J Virol. 2016 Aug 12;90(17):7684-91. doi: 10.1128/JVI.00583-16. Print 2016 Sep 1.

27.

Zika Virus as an Emerging Global Pathogen: Neurological Complications of Zika Virus.

Beckham JD, Pastula DM, Massey A, Tyler KL.

JAMA Neurol. 2016 Jul 1;73(7):875-9. doi: 10.1001/jamaneurol.2016.0800. Review.

28.

Four emerging arboviral diseases in North America: Jamestown Canyon, Powassan, chikungunya, and Zika virus diseases.

Pastula DM, Smith DE, Beckham JD, Tyler KL.

J Neurovirol. 2016 Jun;22(3):257-60. doi: 10.1007/s13365-016-0428-5. Epub 2016 Feb 22. Review.

29.

Arbovirus Infections.

Beckham JD, Tyler KL.

Continuum (Minneap Minn). 2015 Dec;21(6 Neuroinfectious Disease):1599-611. doi: 10.1212/CON.0000000000000240. Review.

30.

2nd International Conference on Progressive Multifocal Leukoencephalopathy (PML) 2015: JCV virology, progressive multifocal leukoencephalopathy pathogenesis, diagnosis and risk stratification, and new approaches to prevention and treatment.

Patera AC, Butler SL, Cinque P, Clifford DB, Elston R, Garcea RL, Major EO, Pavlovic D, Peterson IS, Ryan AM, Tyler KL, Weber T; PML Consortium.

J Neurovirol. 2015 Dec;21(6):702-5. doi: 10.1007/s13365-015-0392-5. No abstract available.

PMID:
26501778
31.

Editorial Commentary: Failure of Adjunctive Valacyclovir to Improve Outcomes in Herpes Simplex Encephalitis.

Tyler KL.

Clin Infect Dis. 2015 Sep 1;61(5):692-4. doi: 10.1093/cid/civ373. Epub 2015 May 8. No abstract available.

PMID:
25956893
32.

Rationale for the evaluation of fluoxetine in the treatment of enterovirus D68-associated acute flaccid myelitis.

Tyler KL.

JAMA Neurol. 2015 May;72(5):493-4. doi: 10.1001/jamaneurol.2014.4625. No abstract available.

33.

Fingolimod and risk of varicella-zoster virus infection: back to the future with an old infection and a new drug.

Tyler KL.

JAMA Neurol. 2015 Jan;72(1):10-3. doi: 10.1001/jamaneurol.2014.3390. No abstract available.

PMID:
25420159
34.

The toll (like receptor 3) to the pathogenesis of herpes simplex encephalitis.

Steiner I, Tyler KL.

Neurology. 2014 Nov 18;83(21):1882-3. doi: 10.1212/WNL.0000000000001011. Epub 2014 Oct 22. No abstract available.

PMID:
25339218
35.

Activation of intrinsic immune responses and microglial phagocytosis in an ex vivo spinal cord slice culture model of West Nile virus infection.

Quick ED, Leser JS, Clarke P, Tyler KL.

J Virol. 2014 Nov;88(22):13005-14. doi: 10.1128/JVI.01994-14. Epub 2014 Aug 27.

36.

West Nile and St. Louis encephalitis viruses.

Oyer RJ, David Beckham J, Tyler KL.

Handb Clin Neurol. 2014;123:433-47. doi: 10.1016/B978-0-444-53488-0.00020-1. No abstract available.

PMID:
25015498
37.

Current developments in understanding of West Nile virus central nervous system disease.

Tyler KL.

Curr Opin Neurol. 2014 Jun;27(3):342-8. doi: 10.1097/WCO.0000000000000088. Review.

39.

Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response.

Clarke P, Leser JS, Quick ED, Dionne KR, Beckham JD, Tyler KL.

J Virol. 2014 Jan;88(2):1080-9. doi: 10.1128/JVI.02944-13. Epub 2013 Nov 6.

40.

A 20-year-old woman with headache and transient numbness.

Tyler KL, Johnson EC, Cantu DS, Haller BL.

Neurohospitalist. 2013 Apr;3(2):101-10. doi: 10.1177/1941874412473118. No abstract available.

41.

Slice culture modeling of central nervous system (CNS) viral infection.

Dionne KR, Tyler KL.

Methods Mol Biol. 2013;1078:97-117. doi: 10.1007/978-1-62703-640-5_9.

42.

Novel approaches and challenges to treatment of central nervous system viral infections.

Nath A, Tyler KL.

Ann Neurol. 2013 Sep;74(3):412-22. doi: 10.1002/ana.23988. Review.

43.

PML therapy: "It's Déjà vu all over again".

Tyler KL.

J Neurovirol. 2013 Aug;19(4):311-3. doi: 10.1007/s13365-013-0191-9. Epub 2013 Aug 3. No abstract available.

44.

Elevated CSF cytokines in the Jarisch-Herxheimer reaction of general paresis.

Davis LE, Oyer R, Beckham JD, Tyler KL.

JAMA Neurol. 2013 Aug;70(8):1060-4. doi: 10.1001/jamaneurol.2013.2120.

PMID:
23732875
45.

Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis.

Dionne KR, Zhuang Y, Leser JS, Tyler KL, Clarke P.

J Virol. 2013 Mar;87(6):3447-60. doi: 10.1128/JVI.02324-12. Epub 2013 Jan 9.

46.

West Nile virus growth is independent of autophagy activation.

Beatman E, Oyer R, Shives KD, Hedman K, Brault AC, Tyler KL, Beckham JD.

Virology. 2012 Nov 10;433(1):262-72. doi: 10.1016/j.virol.2012.08.016. Epub 2012 Aug 29.

47.

Activation of innate immune responses in the central nervous system during reovirus myelitis.

Schittone SA, Dionne KR, Tyler KL, Clarke P.

J Virol. 2012 Aug;86(15):8107-18. doi: 10.1128/JVI.00171-12. Epub 2012 May 23.

48.

Signal transducer and activator of transcription-5 mediates neuronal apoptosis induced by inhibition of Rac GTPase activity.

Stankiewicz TR, Loucks FA, Schroeder EK, Nevalainen MT, Tyler KL, Aktories K, Bouchard RJ, Linseman DA.

J Biol Chem. 2012 May 11;287(20):16835-48. doi: 10.1074/jbc.M111.302166. Epub 2012 Feb 29.

49.

Neuro-intensive care of patients with acute CNS infections.

Beckham JD, Tyler KL.

Neurotherapeutics. 2012 Jan;9(1):124-38. doi: 10.1007/s13311-011-0086-5. Review.

50.

Issues and updates in emerging neurologic viral infections.

Wilson MR, Tyler KL.

Semin Neurol. 2011 Jul;31(3):245-53. doi: 10.1055/s-0031-1287650. Epub 2011 Sep 30. Review.

PMID:
21964843

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