Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 10

1.

A randomized, double-blind, placebo-controlled trial assessing the efficacy of S66913 in patients with paroxysmal atrial fibrillation.

Camm AJ, Dorian P, Hohnloser SH, Kowey PR, Tyl B, Ni Y, Vandzhura V, Maison-Blanche P, de Melis M, Sanders P.

Eur Heart J Cardiovasc Pharmacother. 2019 Jan 1;5(1):21-28. doi: 10.1093/ehjcvp/pvy022.

PMID:
30052825
2.

New medicinal products for chronic heart failure: advances in clinical trial design and efficacy assessment.

Cowie MR, Filippatos GS, Alonso Garcia MLA, Anker SD, Baczynska A, Bloomfield DM, Borentain M, Bruins Slot K, Cronin M, Doevendans PA, El-Gazayerly A, Gimpelewicz C, Honarpour N, Janmohamed S, Janssen H, Kim AM, Lautsch D, Laws I, Lefkowitz M, Lopez-Sendon J, Lyon AR, Malik FI, McMurray JJV, Metra M, Figueroa Perez S, Pfeffer MA, Pocock SJ, Ponikowski P, Prasad K, Richard-Lordereau I, Roessig L, Rosano GMC, Sherman W, Stough WG, Swedberg K, Tyl B, Zannad F, Boulton C, De Graeff P.

Eur J Heart Fail. 2017 Jun;19(6):718-727. doi: 10.1002/ejhf.809. Epub 2017 Mar 27. Review.

3.

The positive frequency-dependent electrophysiological effects of the IKur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation.

Ford J, Milnes J, El Haou S, Wettwer E, Loose S, Matschke K, Tyl B, Round P, Ravens U.

Heart Rhythm. 2016 Feb;13(2):555-64. doi: 10.1016/j.hrthm.2015.10.003. Epub 2015 Oct 13.

4.

Effects of bilastine on T-wave morphology and the QTc interval: a randomized, double-blind, placebo-controlled, thorough QTc study.

Graff C, Struijk JJ, Kanters JK, Andersen MP, Toft E, Tyl B.

Clin Drug Investig. 2012 May 1;32(5):339-51. doi: 10.2165/11599270-000000000-00000.

PMID:
22393898
5.

Lack of significant effect of bilastine administered at therapeutic and supratherapeutic doses and concomitantly with ketoconazole on ventricular repolarization: results of a thorough QT study (TQTS) with QT-concentration analysis.

Tyl B, Kabbaj M, Azzam S, Sologuren A, Valiente R, Reinbolt E, Roupe K, Blanco N, Wheeler W.

J Clin Pharmacol. 2012 Jun;52(6):893-903. doi: 10.1177/0091270011407191. Epub 2011 Jun 3.

PMID:
21642470
6.

Improvement and limitation of the reliability of automated QT measurement by recent algorithms.

Tyl B, Azzam S, Blanco N, Wheeler W.

J Electrocardiol. 2011 May-Jun;44(3):320-5. doi: 10.1016/j.jelectrocard.2010.11.006. Epub 2010 Dec 15.

PMID:
21163494
7.

Comparison of semiautomated and fully automated methods for QT measurement during a thorough QT/QTc study: variability and sample size considerations.

Tyl B, Kabbaj M, Fassi B, De Jode P, Wheeler W.

J Clin Pharmacol. 2009 Aug;49(8):905-15. doi: 10.1177/0091270009337944. Epub 2009 Jun 19.

PMID:
19542314
8.

Detection of clinically significant QTc prolongation in phase I studies in healthy participants: comparison of 2 semiautomated QT measurement methods.

Sarapa N, Francom SF, Azzam SM, Wickremasingha PK, Tyl B.

J Clin Pharmacol. 2009 Jan;49(1):103-8. doi: 10.1177/0091270008326717. Epub 2008 Oct 28. No abstract available.

PMID:
18957527
9.

Magnitude, mechanism, and reproducibility of QT interval differences between superimposed global and individual lead ECG complexes.

Kligfield P, Tyl B, Maarek M, Maison-Blanche P.

Ann Noninvasive Electrocardiol. 2007 Apr;12(2):145-52.

PMID:
17593183
10.

A gene necessary for late sperm function in Drosophila melanogaster.

Geer BW, Bowman JT, Tyl BT.

J Exp Zool. 1979 Sep;209(3):387-94.

PMID:
114601

Supplemental Content

Support Center