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Items: 36


Celiac Disease: A Review of Current Concepts in Pathogenesis, Prevention, and Novel Therapies.

Tye-Din JA, Galipeau HJ, Agardh D.

Front Pediatr. 2018 Nov 21;6:350. doi: 10.3389/fped.2018.00350. eCollection 2018. Review.


Gluten in "gluten-free" manufactured foods in Australia: a cross-sectional study.

Halmos EP, Clarke D, Pizzey C, Tye-Din JA.

Med J Aust. 2018 Nov 19;209(10):448-449. Epub 2018 Nov 12. No abstract available.


Genome mapping of seed-borne allergens and immunoresponsive proteins in wheat.

Juhász A, Belova T, Florides CG, Maulis C, Fischer I, Gell G, Birinyi Z, Ong J, Keeble-Gagnère G, Maharajan A, Ma W, Gibson P, Jia J, Lang D, Mayer KFX, Spannagl M; International Wheat Genome Sequencing Consortium, Tye-Din JA, Appels R, Olsen OA.

Sci Adv. 2018 Aug 17;4(8):eaar8602. doi: 10.1126/sciadv.aar8602. eCollection 2018 Aug.


T cells in coeliac disease: a rational target for diagnosis and therapy.

Hardy MY, Tye-Din JA.

Nat Rev Gastroenterol Hepatol. 2018 Oct;15(10):583-584. doi: 10.1038/s41575-018-0043-4. No abstract available.


Gluten in "gluten-free" food from food outlets in Melbourne: a cross-sectional study.

Halmos EP, Di Bella CA, Webster R, Deng M, Tye-Din JA.

Med J Aust. 2018 Jun 2;209(1):42-43. Epub 2018 May 28. No abstract available.


High rates of variation in HLA-DQ2/DQ8 testing for coeliac disease: results from an RCPAQAP pilot program.

Horan MP, Chai SY, Munusamy N, Tay KH, Wienholt L, Tye-Din JA, Daveson J, Varney M, Badrick T.

J Clin Pathol. 2018 Oct;71(10):900-905. doi: 10.1136/jclinpath-2018-205209. Epub 2018 May 15.


Food knowledge and psychological state predict adherence to a gluten-free diet in a survey of 5310 Australians and New Zealanders with coeliac disease.

Halmos EP, Deng M, Knowles SR, Sainsbury K, Mullan B, Tye-Din JA.

Aliment Pharmacol Ther. 2018 Jul;48(1):78-86. doi: 10.1111/apt.14791. Epub 2018 May 7.


Maintenance of a gluten free diet in coeliac disease: The roles of self-regulation, habit, psychological resources, motivation, support, and goal priority.

Sainsbury K, Halmos EP, Knowles S, Mullan B, Tye-Din JA.

Appetite. 2018 Jun 1;125:356-366. doi: 10.1016/j.appet.2018.02.023. Epub 2018 Feb 24.


Rapid, Loop-Mediated Isothermal Amplification Detection of Celiac Disease Risk Alleles.

Erlichster M, Tye-Din JA, Varney MD, Skafidas E, Kwan P.

J Mol Diagn. 2018 May;20(3):307-315. doi: 10.1016/j.jmoldx.2018.01.005. Epub 2018 Feb 17.


Resolving incomplete single nucleotide polymorphism tagging of HLA-DQ2.2 for coeliac disease genotyping using digital droplet PCR.

Hardy MY, Ontiveros N, Varney MD, Tye-Din JA.

HLA. 2018 Apr;91(4):280-288. doi: 10.1111/tan.13219. Epub 2018 Feb 26.


Editorial: a novel approach to monitor mucosal healing in coeliac disease-as simple as shifting goalposts?

Tye-Din JA.

Aliment Pharmacol Ther. 2017 Nov;46(9):894-895. doi: 10.1111/apt.14287. No abstract available.


Discrepancies in genetic testing results for coeliac disease: call for standardised testing and reporting.

Daveson AJM, Varney M, Jackson KE, Tye-Din JA.

Med J Aust. 2017 Aug 21;207(4):179-180. No abstract available.


Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies.

Goel G, King T, Daveson AJ, Andrews JM, Krishnarajah J, Krause R, Brown GJE, Fogel R, Barish CF, Epstein R, Kinney TP, Miner PB Jr, Tye-Din JA, Girardin A, Taavela J, Popp A, Sidney J, Mäki M, Goldstein KE, Griffin PH, Wang S, Dzuris JL, Williams LJ, Sette A, Xavier RJ, Sollid LM, Jabri B, Anderson RP.

Lancet Gastroenterol Hepatol. 2017 Jul;2(7):479-493. doi: 10.1016/S2468-1253(17)30110-3. Epub 2017 May 11.


The practice and perception of precautionary allergen labelling by the Australasian food manufacturing industry.

Zurzolo GA, Peters RL, Koplin JJ, de Courten M, Mathai ML, Tye-Din JA, Tang MLK, Campbell DE, Ponsonby AL, Prescott SL, Gurrin L, Dharmage SC, Allen KJ.

Clin Exp Allergy. 2017 Jul;47(7):961-968. doi: 10.1111/cea.12923. Epub 2017 Apr 10.


Circulating gluten-specific FOXP3+CD39+ regulatory T cells have impaired suppressive function in patients with celiac disease.

Cook L, Munier CML, Seddiki N, van Bockel D, Ontiveros N, Hardy MY, Gillies JK, Levings MK, Reid HH, Petersen J, Rossjohn J, Anderson RP, Zaunders JJ, Tye-Din JA, Kelleher AD.

J Allergy Clin Immunol. 2017 Dec;140(6):1592-1603.e8. doi: 10.1016/j.jaci.2017.02.015. Epub 2017 Mar 8.


Coeliac disease: a unique model for investigating broken tolerance in autoimmunity.

Hardy MY, Tye-Din JA.

Clin Transl Immunology. 2016 Nov 2;5(11):e112. eCollection 2016 Nov. Review.


Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity.

Caminero A, Galipeau HJ, McCarville JL, Johnston CW, Bernier SP, Russell AK, Jury J, Herran AR, Casqueiro J, Tye-Din JA, Surette MG, Magarvey NA, Schuppan D, Verdu EF.

Gastroenterology. 2016 Oct;151(4):670-83. doi: 10.1053/j.gastro.2016.06.041. Epub 2016 Jun 30.



Hardy MY, Anderson RP, Tye-Din JA.

Gastroenterology. 2016 Mar;150(3):779-80. doi: 10.1053/j.gastro.2016.01.027. Epub 2016 Jan 27. No abstract available.


Genomic prediction of celiac disease targeting HLA-positive individuals.

Abraham G, Rohmer A, Tye-Din JA, Inouye M.

Genome Med. 2015 Jul 16;7(1):72. doi: 10.1186/s13073-015-0196-5. eCollection 2015.


Consistency in polyclonal T-cell responses to gluten between children and adults with celiac disease.

Hardy MY, Girardin A, Pizzey C, Cameron DJ, Watson KA, Picascia S, Auricchio R, Greco L, Gianfrani C, La Gruta NL, Anderson RP, Tye-Din JA.

Gastroenterology. 2015 Nov;149(6):1541-1552.e2. doi: 10.1053/j.gastro.2015.07.013. Epub 2015 Jul 29.


Point-of-care testing for coeliac disease antibodies - what is the evidence?

Newnham ED, Tye-Din JA.

Med J Aust. 2015 May 4;202(8):418-9. No abstract available.


Appropriate clinical use of human leukocyte antigen typing for coeliac disease: an Australasian perspective.

Tye-Din JA, Cameron DJ, Daveson AJ, Day AS, Dellsperger P, Hogan C, Newnham ED, Shepherd SJ, Steele RH, Wienholt L, Varney MD.

Intern Med J. 2015 Apr;45(4):441-50. doi: 10.1111/imj.12716.


Ingestion of oats and barley in patients with celiac disease mobilizes cross-reactive T cells activated by avenin peptides and immuno-dominant hordein peptides.

Hardy MY, Tye-Din JA, Stewart JA, Schmitz F, Dudek NL, Hanchapola I, Purcell AW, Anderson RP.

J Autoimmun. 2015 Jan;56:56-65. doi: 10.1016/j.jaut.2014.10.003. Epub 2014 Nov 1.


Accurate and robust genomic prediction of celiac disease using statistical learning.

Abraham G, Tye-Din JA, Bhalala OG, Kowalczyk A, Zobel J, Inouye M.

PLoS Genet. 2014 Feb 13;10(2):e1004137. doi: 10.1371/journal.pgen.1004137. eCollection 2014 Feb. Erratum in: PLoS Genet. 2014 Apr;10(4):e1004374.


A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways.

Anderson RP, Henry MJ, Taylor R, Duncan EL, Danoy P, Costa MJ, Addison K, Tye-Din JA, Kotowicz MA, Knight RE, Pollock W, Nicholson GC, Toh BH, Brown MA, Pasco JA.

BMC Med. 2013 Aug 28;11:188. doi: 10.1186/1741-7015-11-188.


Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease.

Broughton SE, Petersen J, Theodossis A, Scally SW, Loh KL, Thompson A, van Bergen J, Kooy-Winkelaar Y, Henderson KN, Beddoe T, Tye-Din JA, Mannering SI, Purcell AW, McCluskey J, Anderson RP, Koning F, Reid HH, Rossjohn J.

Immunity. 2012 Oct 19;37(4):611-21. doi: 10.1016/j.immuni.2012.07.013. Epub 2012 Oct 11.


For celiac disease, diagnosis is not enough.

Gibson PR, Shepherd SJ, Tye-Din JA.

Clin Gastroenterol Hepatol. 2012 Aug;10(8):900-1. doi: 10.1016/j.cgh.2012.03.020. Epub 2012 Apr 10. No abstract available.


Dissecting the T-cell response to hordeins in coeliac disease can develop barley with reduced immunotoxicity.

Tanner GJ, Howitt CA, Forrester RI, Campbell PM, Tye-Din JA, Anderson RP.

Aliment Pharmacol Ther. 2010 Nov;32(9):1184-91. doi: 10.1111/j.1365-2036.2010.04452.x. Epub 2010 Sep 15.


Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease.

Tye-Din JA, Stewart JA, Dromey JA, Beissbarth T, van Heel DA, Tatham A, Henderson K, Mannering SI, Gianfrani C, Jewell DP, Hill AV, McCluskey J, Rossjohn J, Anderson RP.

Sci Transl Med. 2010 Jul 21;2(41):41ra51. doi: 10.1126/scitranslmed.3001012.


Surveillance of FAP: a prospective blinded comparison of capsule endoscopy and other GI imaging to detect small bowel polyps.

Tescher P, Macrae FA, Speer T, Stella D, Gibson R, Tye-Din JA, Srivatsa G, Jones IT, Marion K.

Hered Cancer Clin Pract. 2010 Apr 4;8(1):3. doi: 10.1186/1897-4287-8-3.


The effects of ALV003 pre-digestion of gluten on immune response and symptoms in celiac disease in vivo.

Tye-Din JA, Anderson RP, Ffrench RA, Brown GJ, Hodsman P, Siegel M, Botwick W, Shreeniwas R.

Clin Immunol. 2010 Mar;134(3):289-95. doi: 10.1016/j.clim.2009.11.001. Epub 2009 Nov 25.


A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease.

Henderson KN, Tye-Din JA, Reid HH, Chen Z, Borg NA, Beissbarth T, Tatham A, Mannering SI, Purcell AW, Dudek NL, van Heel DA, McCluskey J, Rossjohn J, Anderson RP.

Immunity. 2007 Jul;27(1):23-34. Epub 2007 Jul 12.


Antagonists and non-toxic variants of the dominant wheat gliadin T cell epitope in coeliac disease.

Anderson RP, van Heel DA, Tye-Din JA, Jewell DP, Hill AV.

Gut. 2006 Apr;55(4):485-91. Epub 2005 Nov 18.


T cells in peripheral blood after gluten challenge in coeliac disease.

Anderson RP, van Heel DA, Tye-Din JA, Barnardo M, Salio M, Jewell DP, Hill AV.

Gut. 2005 Sep;54(9):1217-23.


A systematic approach for comprehensive T-cell epitope discovery using peptide libraries.

Beissbarth T, Tye-Din JA, Smyth GK, Speed TP, Anderson RP.

Bioinformatics. 2005 Jun;21 Suppl 1:i29-37.


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