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Items: 1 to 50 of 113

1.

Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness.

Tye BW, Commins N, Ryazanova LV, Wühr M, Springer M, Pincus D, Churchman LS.

Elife. 2019 Mar 7;8. pii: e43002. doi: 10.7554/eLife.43002.

2.

Structure of the origin recognition complex bound to DNA replication origin.

Li N, Lam WH, Zhai Y, Cheng J, Cheng E, Zhao Y, Gao N, Tye BK.

Nature. 2018 Jul;559(7713):217-222. doi: 10.1038/s41586-018-0293-x. Epub 2018 Jul 4.

PMID:
29973722
3.

Structure of the MCM2-7 Double Hexamer and Its Implications for the Mechanistic Functions of the Mcm2-7 Complex.

Zhai Y, Tye BK.

Adv Exp Med Biol. 2017;1042:189-205. doi: 10.1007/978-981-10-6955-0_9. Review.

PMID:
29357059
4.

Desorption of harmful hydrocarbon compounds in soil using micron-sized magnetic particles and high-frequency magnetic fields.

Tye BS, Vyas RJ.

Heliyon. 2017 Oct 10;3(10):e00418. doi: 10.1016/j.heliyon.2017.e00418. eCollection 2017 Oct.

5.

Unique Roles of the Non-identical MCM Subunits in DNA Replication Licensing.

Zhai Y, Li N, Jiang H, Huang X, Gao N, Tye BK.

Mol Cell. 2017 Jul 20;67(2):168-179. doi: 10.1016/j.molcel.2017.06.016. Review.

6.

Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer.

Zhai Y, Cheng E, Wu H, Li N, Yung PY, Gao N, Tye BK.

Nat Struct Mol Biol. 2017 Mar;24(3):300-308. doi: 10.1038/nsmb.3374. Epub 2017 Feb 13.

PMID:
28191894
7.

Development and production of good manufacturing practice grade human embryonic stem cell lines as source material for clinical application.

De Sousa PA, Downie JM, Tye BJ, Bruce K, Dand P, Dhanjal S, Serhal P, Harper J, Turner M, Bateman M.

Stem Cell Res. 2016 Sep;17(2):379-390. doi: 10.1016/j.scr.2016.08.011. Epub 2016 Aug 26.

8.

Derivation of the clinical grade human embryonic stem cell line RCe015-A (RC-11).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Laurie A, Canham M, Kunath T, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Jul;17(1):42-48. doi: 10.1016/j.scr.2016.04.021. Epub 2016 May 7.

9.

Derivation of the clinical grade human embryonic stem cell line RCe013-A (RC-9).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Canham MA, Kunath T, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Jul;17(1):36-41. doi: 10.1016/j.scr.2016.04.020. Epub 2016 May 6.

10.

Derivation of the clinical grade human embryonic stem cell line RCe021-A (RC-17).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Allan D, Laurie A, Kunath T, Canham MA, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Jul;17(1):1-5. doi: 10.1016/j.scr.2016.04.019. Epub 2016 Apr 30.

11.

Derivation of the clinical grade human embryonic stem cell line RCe020-a (RC-16).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Laurie A, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 May;16(3):790-4. doi: 10.1016/j.scr.2016.04.002. Epub 2016 Apr 9.

12.

Derivation of the clinical grade human embryonic stem cell line RCe016-A (RC-12).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Laurie A, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 May;16(3):770-5. doi: 10.1016/j.scr.2016.04.001. Epub 2016 Apr 14.

13.

Derivation of the clinical grade human embryonic stem cell line RCe018-A (RC-14).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Laurie A, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 May;16(3):761-5. doi: 10.1016/j.scr.2016.04.004. Epub 2016 Apr 13.

14.

Derivation of the clinical grade human embryonic stem cell line RCe017-A (RC-13).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Laurie A, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 May;16(3):756-60. doi: 10.1016/j.scr.2016.04.006. Epub 2016 Apr 13.

15.

Derivation of the clinical grade human embryonic stem cell line RCe019-A (RC-15).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Laurie A, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 May;16(3):751-5. doi: 10.1016/j.scr.2016.04.003. Epub 2016 Apr 13.

16.

Derivation of the human embryonic stem cell line RCe008-A (RC-4).

De Sousa PA, Tye B, Bruce K, Dand P, Gardner J, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 May;16(3):607-10. doi: 10.1016/j.scr.2016.02.039. Epub 2016 Mar 3.

17.

Derivation of the human embryonic stem cell line RCe007-A (RC-3).

De Sousa PA, Tye B, Bruce K, Dand P, Russell G, Gardner J, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 May;16(3):593-6. doi: 10.1016/j.scr.2016.02.041. Epub 2016 Mar 9.

18.

Derivation of the human embryonic stem cell line RCe014-A (RC-10).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, Bradburn H, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Mar;16(2):537-40. doi: 10.1016/j.scr.2016.02.034. Epub 2016 Feb 23.

19.

Derivation of the human embryonic stem cell line RCe012-A (RC-8).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, Bradburn H, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Mar;16(2):489-92. doi: 10.1016/j.scr.2016.02.033. Epub 2016 Feb 23.

20.

Derivation of the human embryonic stem cell line RCe011-A (RC-7).

De Sousa PA, Tye BJ, Collins DM, Bruce K, Dand P, Russell G, Bradburn H, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Mar;16(2):485-8. doi: 10.1016/j.scr.2016.02.036. Epub 2016 Feb 23.

21.

Derivation of the human embryonic stem cell line RCe010-A (RC-6).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Bradburn H, Gardner J, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Mar;16(2):481-4. doi: 10.1016/j.scr.2016.02.035. Epub 2016 Feb 23.

22.

Derivation of the human embryonic stem cell line RCM1.

De Sousa PA, Tye BJ, Sneddon S, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Gardner J, Downie JM, Courtney A, Brison DR.

Stem Cell Res. 2016 Mar;16(2):476-80. doi: 10.1016/j.scr.2015.12.020. Epub 2015 Dec 31.

23.

Derivation of the human embryonic stem cell line RCe006-A (RC-2).

De Sousa PA, Tye B, Bruce K, Dand P, Russell G, Gardner J, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Mar;16(2):452-5. doi: 10.1016/j.scr.2016.02.029. Epub 2016 Feb 16.

24.

Derivation of the human embryonic stem cell line RCe009-A (RC-5).

De Sousa PA, Tye B, Bruce K, Dand P, Russell G, Collins DM, Gardner J, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Mar;16(2):418-22. doi: 10.1016/j.scr.2016.02.030. Epub 2016 Feb 16.

25.

Structure of the eukaryotic MCM complex at 3.8 Å.

Li N, Zhai Y, Zhang Y, Li W, Yang M, Lei J, Tye BK, Gao N.

Nature. 2015 Aug 13;524(7564):186-91. doi: 10.1038/nature14685. Epub 2015 Jul 29.

PMID:
26222030
26.

Small molecule gated split-tyrosine phosphatases and orthogonal split-tyrosine kinases.

Camacho-Soto K, Castillo-Montoya J, Tye B, Ogunleye LO, Ghosh I.

J Am Chem Soc. 2014 Dec 10;136(49):17078-86. doi: 10.1021/ja5080745. Epub 2014 Nov 26.

PMID:
25409264
27.

Program evaluation of remote heart failure monitoring: healthcare utilization analysis in a rural regional medical center.

Riley WT, Keberlein P, Sorenson G, Mohler S, Tye B, Ramirez AS, Carroll M.

Telemed J E Health. 2015 Mar;21(3):157-62. doi: 10.1089/tmj.2014.0093. Epub 2014 Jul 15.

28.

Ligand-gated split-kinases.

Camacho-Soto K, Castillo-Montoya J, Tye B, Ghosh I.

J Am Chem Soc. 2014 Mar 12;136(10):3995-4002. doi: 10.1021/ja4130803. Epub 2014 Feb 28.

PMID:
24533431
29.

Derivation of vascular endothelial cells from human embryonic stem cells under GMP-compliant conditions: towards clinical studies in ischaemic disease.

Kaupisch A, Kennedy L, Stelmanis V, Tye B, Kane NM, Mountford JC, Courtney A, Baker AH.

J Cardiovasc Transl Res. 2012 Oct;5(5):605-17. Epub 2012 Aug 2.

PMID:
22855254
30.

Novel features of ARS selection in budding yeast Lachancea kluyveri.

Liachko I, Tanaka E, Cox K, Chung SC, Yang L, Seher A, Hallas L, Cha E, Kang G, Pace H, Barrow J, Inada M, Tye BK, Keich U.

BMC Genomics. 2011 Dec 28;12:633. doi: 10.1186/1471-2164-12-633.

31.

Structural insights into the Cdt1-mediated MCM2-7 chromatin loading.

Liu C, Wu R, Zhou B, Wang J, Wei Z, Tye BK, Liang C, Zhu G.

Nucleic Acids Res. 2012 Apr;40(7):3208-17. doi: 10.1093/nar/gkr1118. Epub 2011 Dec 2.

32.

Old-fashioned genetic screens give new insights to DNA replication.

Tye BK.

Cell Cycle. 2010 Dec 1;9(23):4610-1. No abstract available.

PMID:
21260947
33.

Ploidy dictates repair pathway choice under DNA replication stress.

Li XC, Tye BK.

Genetics. 2011 Apr;187(4):1031-40. doi: 10.1534/genetics.110.125450. Epub 2011 Jan 17.

34.

A comprehensive genome-wide map of autonomously replicating sequences in a naive genome.

Liachko I, Bhaskar A, Lee C, Chung SC, Tye BK, Keich U.

PLoS Genet. 2010 May 13;6(5):e1000946. doi: 10.1371/journal.pgen.1000946.

35.

Alternative mechanisms for coordinating polymerase alpha and MCM helicase.

Lee C, Liachko I, Bouten R, Kelman Z, Tye BK.

Mol Cell Biol. 2010 Jan;30(2):423-35. doi: 10.1128/MCB.01240-09. Epub 2009 Nov 16.

36.

Aneuploidy and improved growth are coincident but not causal in a yeast cancer model.

Li XC, Schimenti JC, Tye BK.

PLoS Biol. 2009 Jul;7(7):e1000161. doi: 10.1371/journal.pbio.1000161. Epub 2009 Jul 28.

37.

Novel DNA binding properties of the Mcm10 protein from Saccharomyces cerevisiae.

Eisenberg S, Korza G, Carson J, Liachko I, Tye BK.

J Biol Chem. 2009 Sep 11;284(37):25412-20. doi: 10.1074/jbc.M109.033175. Epub 2009 Jul 15.

38.

Clinically failed eggs as a source of normal human embryo stem cells.

De Sousa PA, Gardner J, Sneddon S, Pells S, Tye BJ, Dand P, Collins DM, Stewart K, Shaw L, Przyborski S, Cooke M, McLaughlin KJ, Kimber SJ, Lieberman BA, Wilmut I, Brison DR.

Stem Cell Res. 2009 May;2(3):188-97. doi: 10.1016/j.scr.2009.01.002. Epub 2009 Feb 6.

39.

Memories of Ray Wu by a colleague.

Tye BK.

Sci China C Life Sci. 2009 Feb;52(2):133-4. doi: 10.1007/s11427-009-0027-2. No abstract available.

PMID:
19277524
40.

Mcm10 mediates the interaction between DNA replication and silencing machineries.

Liachko I, Tye BK.

Genetics. 2009 Feb;181(2):379-91. doi: 10.1534/genetics.108.099101. Epub 2008 Dec 8.

41.

Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast.

Keich U, Gao H, Garretson JS, Bhaskar A, Liachko I, Donato J, Tye BK.

BMC Bioinformatics. 2008 Sep 12;9:372. doi: 10.1186/1471-2105-9-372.

42.

Bone tissue formation from human embryonic stem cells in vivo.

Tremoleda JL, Forsyth NR, Khan NS, Wojtacha D, Christodoulou I, Tye BJ, Racey SN, Collishaw S, Sottile V, Thomson AJ, Simpson AH, Noble BS, McWhir J.

Cloning Stem Cells. 2008 Mar;10(1):119-32. doi: 10.1089/clo.2007.0R36.

PMID:
18241129
43.

A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice.

Shima N, Alcaraz A, Liachko I, Buske TR, Andrews CA, Munroe RJ, Hartford SA, Tye BK, Schimenti JC.

Nat Genet. 2007 Jan;39(1):93-8. Epub 2006 Dec 3.

PMID:
17143284
44.

Endolyn (CD164) modulates the CXCL12-mediated migration of umbilical cord blood CD133+ cells.

Forde S, Tye BJ, Newey SE, Roubelakis M, Smythe J, McGuckin CP, Pettengell R, Watt SM.

Blood. 2007 Mar 1;109(5):1825-33. Epub 2006 Oct 31.

PMID:
17077324
45.

Genome-wide hierarchy of replication origin usage in Saccharomyces cerevisiae.

Donato JJ, Chung SC, Tye BK.

PLoS Genet. 2006 Sep 8;2(9):e141. Epub 2006 Jul 25.

46.
47.

Dual functional regulators coordinate DNA replication and gene expression in proliferating cells.

Tye BK, Chang VK.

Front Biosci. 2004 Sep 1;9:2548-55. Review.

PMID:
15358580
48.

Mcm1 promotes replication initiation by binding specific elements at replication origins.

Chang VK, Donato JJ, Chan CS, Tye BK.

Mol Cell Biol. 2004 Jul;24(14):6514-24.

49.

Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae.

Sawyer SL, Cheng IH, Chai W, Tye BK.

J Mol Biol. 2004 Jul 2;340(2):195-202.

PMID:
15201046
50.

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