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Items: 1 to 50 of 95

1.

Glyco-Engineering of Plant-Based Expression Systems.

Fischer R, Holland T, Sack M, Schillberg S, Stoger E, Twyman RM, Buyel JF.

Adv Biochem Eng Biotechnol. 2018 Aug 2. doi: 10.1007/10_2018_76. [Epub ahead of print]

PMID:
30069741
2.

Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm.

Vamvaka E, Farré G, Molinos-Albert LM, Evans A, Canela-Xandri A, Twyman RM, Carrillo J, Ordóñez RA, Shattock RJ, O'Keefe BR, Clotet B, Blanco J, Khush GS, Christou P, Capell T.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7854-E7862. doi: 10.1073/pnas.1806022115. Epub 2018 Jul 30.

3.

The FT/FD-dependent initiation of flowering under long-day conditions in the day-neutral species Nicotiana tabacum originates from the facultative short-day ancestor Nicotiana tomentosiformis.

Beinecke FA, Grundmann L, Wiedmann DR, Schmidt FJ, Caesar AS, Zimmermann M, Lahme M, Twyman RM, Prüfer D, Noll GA.

Plant J. 2018 Jul 21. doi: 10.1111/tpj.14033. [Epub ahead of print]

PMID:
30030859
4.

Very-large-scale production of antibodies in plants: The biologization of manufacturing.

Buyel JF, Twyman RM, Fischer R.

Biotechnol Adv. 2017 Jul;35(4):458-465. doi: 10.1016/j.biotechadv.2017.03.011. Epub 2017 Mar 25. Review.

5.

Antibodies from plants for bionanomaterials.

Edgue G, Twyman RM, Beiss V, Fischer R, Sack M.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Nov;9(6). doi: 10.1002/wnan.1462. Epub 2017 Mar 27. Review.

PMID:
28345261
6.

Biofortification of crops with nutrients: factors affecting utilization and storage.

Díaz-Gómez J, Twyman RM, Zhu C, Farré G, Serrano JC, Portero-Otin M, Muñoz P, Sandmann G, Capell T, Christou P.

Curr Opin Biotechnol. 2017 Apr;44:115-123. doi: 10.1016/j.copbio.2016.12.002. Epub 2017 Jan 6. Review.

PMID:
28068552
7.

The distribution of carotenoids in hens fed on biofortified maize is influenced by feed composition, absorption, resource allocation and storage.

Moreno JA, Díaz-Gómez J, Nogareda C, Angulo E, Sandmann G, Portero-Otin M, Serrano JC, Twyman RM, Capell T, Zhu C, Christou P.

Sci Rep. 2016 Oct 14;6:35346. doi: 10.1038/srep35346.

8.

Characteristics of Genome Editing Mutations in Cereal Crops.

Zhu C, Bortesi L, Baysal C, Twyman RM, Fischer R, Capell T, Schillberg S, Christou P.

Trends Plant Sci. 2017 Jan;22(1):38-52. doi: 10.1016/j.tplants.2016.08.009. Epub 2016 Sep 17. Review.

PMID:
27645899
9.

Patterns of CRISPR/Cas9 activity in plants, animals and microbes.

Bortesi L, Zhu C, Zischewski J, Perez L, Bassié L, Nadi R, Forni G, Lade SB, Soto E, Jin X, Medina V, Villorbina G, Muñoz P, Farré G, Fischer R, Twyman RM, Capell T, Christou P, Schillberg S.

Plant Biotechnol J. 2016 Dec;14(12):2203-2216. doi: 10.1111/pbi.12634. Epub 2016 Oct 11. Review.

10.

A Plant-Based Transient Expression System for the Rapid Production of Malaria Vaccine Candidates.

Boes A, Reimann A, Twyman RM, Fischer R, Schillberg S, Spiegel H.

Methods Mol Biol. 2016;1404:597-619. doi: 10.1007/978-1-4939-3389-1_39.

PMID:
27076325
11.

Virus-based nanoparticles as platform technologies for modern vaccines.

Lee KL, Twyman RM, Fiering S, Steinmetz NF.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Jul;8(4):554-78. doi: 10.1002/wnan.1383. Epub 2016 Jan 19. Review.

12.

Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants.

Ma JK, Drossard J, Lewis D, Altmann F, Boyle J, Christou P, Cole T, Dale P, van Dolleweerd CJ, Isitt V, Katinger D, Lobedan M, Mertens H, Paul MJ, Rademacher T, Sack M, Hundleby PA, Stiegler G, Stoger E, Twyman RM, Vcelar B, Fischer R.

Plant Biotechnol J. 2015 Oct;13(8):1106-20. doi: 10.1111/pbi.12416. Epub 2015 Jul 3.

13.

Extraction and downstream processing of plant-derived recombinant proteins.

Buyel JF, Twyman RM, Fischer R.

Biotechnol Adv. 2015 Nov 1;33(6 Pt 1):902-13. doi: 10.1016/j.biotechadv.2015.04.010. Epub 2015 Apr 25. Review.

PMID:
25922318
14.

Rice endosperm produces an underglycosylated and potent form of the HIV-neutralizing monoclonal antibody 2G12.

Vamvaka E, Twyman RM, Murad AM, Melnik S, Teh AY, Arcalis E, Altmann F, Stoger E, Rech E, Ma JK, Christou P, Capell T.

Plant Biotechnol J. 2016 Jan;14(1):97-108. doi: 10.1111/pbi.12360. Epub 2015 Apr 7.

15.

Insect antimicrobial peptides show potentiating functional interactions against Gram-negative bacteria.

Rahnamaeian M, Cytryńska M, Zdybicka-Barabas A, Dobslaff K, Wiesner J, Twyman RM, Zuchner T, Sadd BM, Regoes RR, Schmid-Hempel P, Vilcinskas A.

Proc Biol Sci. 2015 May 7;282(1806):20150293. doi: 10.1098/rspb.2015.0293.

16.

Identification of a Taraxacum brevicorniculatum rubber elongation factor protein that is localized on rubber particles and promotes rubber biosynthesis.

Laibach N, Hillebrand A, Twyman RM, Prüfer D, Schulze Gronover C.

Plant J. 2015 May;82(4):609-20. doi: 10.1111/tpj.12836. Epub 2015 Apr 21.

17.

Insects as models to study the epigenetic basis of disease.

Mukherjee K, Twyman RM, Vilcinskas A.

Prog Biophys Mol Biol. 2015 Jul;118(1-2):69-78. doi: 10.1016/j.pbiomolbio.2015.02.009. Epub 2015 Mar 14. Review.

18.

Uncertain role of MtSEO-F3 in assembly of Medicago truncatula forisomes.

Groscurth S, Müller B, Visser F, Blob B, Menzel M, Rüping BA, Twyman RM, Prüfer D, Noll GA.

Plant Signal Behav. 2014;9(9):e29581. doi: 10.4161/psb.29581.

19.

The Impact of Aspect Ratio on the Biodistribution and Tumor Homing of Rigid Soft-Matter Nanorods.

Shukla S, Eber FJ, Nagarajan AS, DiFranco NA, Schmidt N, Wen AM, Eiben S, Twyman RM, Wege C, Steinmetz NF.

Adv Healthc Mater. 2015 Apr 22;4(6):874-82. doi: 10.1002/adhm.201400641. Epub 2015 Jan 13.

20.

High-value products from plants: the challenges of process optimization.

Fischer R, Vasilev N, Twyman RM, Schillberg S.

Curr Opin Biotechnol. 2015 Apr;32:156-162. doi: 10.1016/j.copbio.2014.12.018. Epub 2015 Jan 3. Review.

PMID:
25562816
21.

Comparative evaluation of heterologous production systems for recombinant pulmonary surfactant protein D.

Salgado D, Fischer R, Schillberg S, Twyman RM, Rasche S.

Front Immunol. 2014 Dec 8;5:623. doi: 10.3389/fimmu.2014.00623. eCollection 2014. Review.

22.

Knowledge-driven approaches for engineering complex metabolic pathways in plants.

Farré G, Twyman RM, Christou P, Capell T, Zhu C.

Curr Opin Biotechnol. 2015 Apr;32:54-60. doi: 10.1016/j.copbio.2014.11.004. Epub 2014 Nov 25. Review.

PMID:
25448233
23.

The characteristics and potential applications of structural lipid droplet proteins in plants.

Laibach N, Post J, Twyman RM, Gronover CS, Prüfer D.

J Biotechnol. 2015 May 10;201:15-27. doi: 10.1016/j.jbiotec.2014.08.020. Epub 2014 Aug 23. Review.

PMID:
25160916
24.

Uncertain role of MtSEO-F3 in assembly of Medicago truncatula forisomes.

Groscurth S, Müller B, Visser F, Blob B, Menzel M, Rüping BA, Twyman RM, Prüfer D, Noll G.

Plant Signal Behav. 2014 Jun 18;9. pii: e29581. [Epub ahead of print]

PMID:
24940601
25.

Characterization of five subgroups of the sieve element occlusion gene family in Glycine max reveals genes encoding non-forisome P-proteins, forisomes and forisome tails.

Zielonka S, Ernst AM, Hawat S, Twyman RM, Prüfer D, Noll GA.

Plant Mol Biol. 2014 Sep;86(1-2):51-67. doi: 10.1007/s11103-014-0211-z. Epub 2014 Jun 14.

PMID:
24928491
26.

Molecular and ultrastructural analysis of forisome subunits reveals the principles of forisome assembly.

Müller B, Groscurth S, Menzel M, Rüping BA, Twyman RM, Prüfer D, Noll GA.

Ann Bot. 2014 Jun;113(7):1121-37. doi: 10.1093/aob/mcu036. Epub 2014 Apr 2.

27.

Can plant biotechnology help break the HIV-malaria link?

Vamvaka E, Twyman RM, Christou P, Capell T.

Biotechnol Adv. 2014 May-Jun;32(3):575-82. doi: 10.1016/j.biotechadv.2014.02.004. Epub 2014 Mar 6. Review.

PMID:
24607600
28.

Strategic patent analysis in plant biotechnology: terpenoid indole alkaloid metabolic engineering as a case study.

Miralpeix B, Sabalza M, Twyman RM, Capell T, Christou P.

Plant Biotechnol J. 2014 Feb;12(2):117-34. doi: 10.1111/pbi.12134. Review.

29.

Engineering metabolic pathways in plants by multigene transformation.

Zorrilla-López U, Masip G, Arjó G, Bai C, Banakar R, Bassie L, Berman J, Farré G, Miralpeix B, Pérez-Massot E, Sabalza M, Sanahuja G, Vamvaka E, Twyman RM, Christou P, Zhu C, Capell T.

Int J Dev Biol. 2013;57(6-8):565-76. doi: 10.1387/ijdb.130162pc. Review.

30.

A question of balance: achieving appropriate nutrient levels in biofortified staple crops.

Sanahuja G, Farré G, Berman J, Zorrilla-López U, Twyman RM, Capell T, Christou P, Zhu C.

Nutr Res Rev. 2013 Dec;26(2):235-45. doi: 10.1017/S0954422413000176. Epub 2013 Oct 18. Review.

PMID:
24134863
31.

Molecular farming in tobacco hairy roots by triggering the secretion of a pharmaceutical antibody.

Häkkinen ST, Raven N, Henquet M, Laukkanen ML, Anderlei T, Pitkänen JP, Twyman RM, Bosch D, Oksman-Caldentey KM, Schillberg S, Ritala A.

Biotechnol Bioeng. 2014 Feb;111(2):336-46. doi: 10.1002/bit.25113. Epub 2013 Sep 24.

PMID:
24030771
32.

P-proteins in Arabidopsis are heteromeric structures involved in rapid sieve tube sealing.

Jekat SB, Ernst AM, von Bohl A, Zielonka S, Twyman RM, Noll GA, Prüfer D.

Front Plant Sci. 2013 Jul 3;4:225. doi: 10.3389/fpls.2013.00225. eCollection 2013.

33.

Cellulases from insects.

Fischer R, Ostafe R, Twyman RM.

Adv Biochem Eng Biotechnol. 2013;136:51-64. doi: 10.1007/10_2013_206.

PMID:
23728162
34.

Paradoxical EU agricultural policies on genetically engineered crops.

Masip G, Sabalza M, Pérez-Massot E, Banakar R, Cebrian D, Twyman RM, Capell T, Albajes R, Christou P.

Trends Plant Sci. 2013 Jun;18(6):312-24. doi: 10.1016/j.tplants.2013.03.004. Epub 2013 Apr 25. Review.

PMID:
23623240
35.

Can the world afford to ignore biotechnology solutions that address food insecurity?

Berman J, Zhu C, Pérez-Massot E, Arjó G, Zorrilla-López U, Masip G, Banakar R, Sanahuja G, Farré G, Miralpeix B, Bai C, Vamvaka E, Sabalza M, Twyman RM, Bassié L, Capell T, Christou P.

Plant Mol Biol. 2013 Sep;83(1-2):5-19. doi: 10.1007/s11103-013-0027-2. Epub 2013 Feb 21.

PMID:
23430566
36.

Molecular farming of pharmaceutical proteins using plant suspension cell and tissue cultures.

Schillberg S, Raven N, Fischer R, Twyman RM, Schiermeyer A.

Curr Pharm Des. 2013;19(31):5531-42. Review.

PMID:
23394569
37.

Optimizing the yield of recombinant pharmaceutical proteins in plants.

Twyman RM, Schillberg S, Fischer R.

Curr Pharm Des. 2013;19(31):5486-94. Review.

PMID:
23394567
38.

Commercial aspects of pharmaceutical protein production in plants.

Fischer R, Schillberg S, Buyel JF, Twyman RM.

Curr Pharm Des. 2013;19(31):5471-7.

PMID:
23394566
39.

Target product selection - where can Molecular Pharming make the difference?

Paul MJ, Teh AY, Twyman RM, Ma JK.

Curr Pharm Des. 2013;19(31):5478-85. Review.

PMID:
23394563
40.

Longevity in the red flour beetle Tribolium castaneum is enhanced by broccoli and depends on nrf-2, jnk-1 and foxo-1 homologous genes.

Grünwald S, Stellzig J, Adam IV, Weber K, Binger S, Boll M, Knorr E, Twyman RM, Vilcinskas A, Wenzel U.

Genes Nutr. 2013 Sep;8(5):439-48. doi: 10.1007/s12263-012-0330-6. Epub 2013 Jan 16.

41.

Abscisic acid-dependent regulation of small rubber particle protein gene expression in Taraxacum brevicorniculatum is mediated by TbbZIP1.

Fricke J, Hillebrand A, Twyman RM, Prüfer D, Schulze Gronover C.

Plant Cell Physiol. 2013 Apr;54(4):448-64. doi: 10.1093/pcp/pcs182. Epub 2013 Jan 9.

PMID:
23303876
42.

Artificial forisomes are ideal models of forisome assembly and activity that allow the development of technical devices.

Groscurth S, Müller B, Schwan S, Menzel M, Diekstall F, Senft M, Kendall A, Kommor BA, Neumann U, Kalischuk M, Kawchuk LM, Krzyzanek V, Heilmann A, Stubbs G, Twyman RM, Prüfer D, Noll GA.

Biomacromolecules. 2012 Oct 8;13(10):3076-86. doi: 10.1021/bm3008499. Epub 2012 Sep 24.

PMID:
22963540
43.

The contribution of transgenic plants to better health through improved nutrition: opportunities and constraints.

Pérez-Massot E, Banakar R, Gómez-Galera S, Zorrilla-López U, Sanahuja G, Arjó G, Miralpeix B, Vamvaka E, Farré G, Rivera SM, Dashevskaya S, Berman J, Sabalza M, Yuan D, Bai C, Bassie L, Twyman RM, Capell T, Christou P, Zhu C.

Genes Nutr. 2013 Jan;8(1):29-41. doi: 10.1007/s12263-012-0315-5. Epub 2012 Aug 29.

44.

Proteins from the FLOWERING LOCUS T-like subclade of the PEBP family act antagonistically to regulate floral initiation in tobacco.

Harig L, Beinecke FA, Oltmanns J, Muth J, Müller O, Rüping B, Twyman RM, Fischer R, Prüfer D, Noll GA.

Plant J. 2012 Dec;72(6):908-21. doi: 10.1111/j.1365-313X.2012.05125.x. Epub 2012 Oct 15.

45.

Sieve element occlusion (SEO) genes encode structural phloem proteins involved in wound sealing of the phloem.

Ernst AM, Jekat SB, Zielonka S, Müller B, Neumann U, Rüping B, Twyman RM, Krzyzanek V, Prüfer D, Noll GA.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):E1980-9. doi: 10.1073/pnas.1202999109. Epub 2012 Jun 25.

46.

Multiple cis-regulatory elements are involved in the complex regulation of the sieve element-specific MtSEO-F1 promoter from Medicago truncatula.

Bucsenez M, Rüping B, Behrens S, Twyman RM, Noll GA, Prüfer D.

Plant Biol (Stuttg). 2012 Sep;14(5):714-24. doi: 10.1111/j.1438-8677.2011.00556.x. Epub 2012 Mar 8.

PMID:
22404711
47.

Using storage organelles for the accumulation and encapsulation of recombinant proteins.

Khan I, Twyman RM, Arcalis E, Stoger E.

Biotechnol J. 2012 Sep;7(9):1099-108. doi: 10.1002/biot.201100089. Epub 2012 Mar 7. Review.

PMID:
22396218
48.

Combinatorial genetic transformation of cereals and the creation of metabolic libraries for the carotenoid pathway.

Farre G, Naqvi S, Sanahuja G, Bai C, Zorrilla-López U, Rivera SM, Canela R, Sandman G, Twyman RM, Capell T, Zhu C, Christou P.

Methods Mol Biol. 2012;847:419-35. doi: 10.1007/978-1-61779-558-9_33.

PMID:
22351026
49.

Field trials and tribulations--making sense of the regulations for experimental field trials of transgenic crops in Europe.

Gómez-Galera S, Twyman RM, Sparrow PA, Van Droogenbroeck B, Custers R, Capell T, Christou P.

Plant Biotechnol J. 2012 Jun;10(5):511-23. doi: 10.1111/j.1467-7652.2012.00681.x. Epub 2012 Jan 30. Review.

50.

Laticifer-specific cis-prenyltransferase silencing affects the rubber, triterpene, and inulin content of Taraxacum brevicorniculatum.

Post J, van Deenen N, Fricke J, Kowalski N, Wurbs D, Schaller H, Eisenreich W, Huber C, Twyman RM, Prüfer D, Gronover CS.

Plant Physiol. 2012 Mar;158(3):1406-17. doi: 10.1104/pp.111.187880. Epub 2012 Jan 11.

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