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Cerebrovascular Blood Flow in Patients with Tetralogy of Fallot: Prediction for Early Surgical Intervention.

Campbell M, Ronai C, Punn R, Tacy T, Tworetzky W, Madriago E.

Prenat Diagn. 2019 Sep 16. doi: 10.1002/pd.5561. [Epub ahead of print]


Early-Emerging Sulcal Patterns Are Atypical in Fetuses with Congenital Heart Disease.

Ortinau CM, Rollins CK, Gholipour A, Yun HJ, Marshall M, Gagoski B, Afacan O, Friedman K, Tworetzky W, Warfield SK, Newburger JW, Inder TE, Grant PE, Im K.

Cereb Cortex. 2018 Oct 1. doi: 10.1093/cercor/bhy235. [Epub ahead of print]


Clinical and Hemodynamic Results After Conversion from Single to Biventricular Circulation After Fetal Aortic Stenosis Intervention.

Barry OM, Friedman KG, Bergersen L, Emani S, Moeyersoms A, Tworetzky W, Marshall AC, Lock JE.

Am J Cardiol. 2018 Aug 1;122(3):511-516. doi: 10.1016/j.amjcard.2018.04.035. Epub 2018 May 1.


Echocardiographic predictors of neonatal illness severity in fetuses with critical left heart obstruction with intact or restrictive atrial septum.

Gellis L, Drogosz M, Lu M, Sleeper LA, Cheng H, Allan C, Marshall AC, Tworetzky W, Friedman KG.

Prenat Diagn. 2018 Sep;38(10):788-794. doi: 10.1002/pd.5322. Epub 2018 Jul 16.


Early hemodynamic changes after fetal aortic stenosis valvuloplasty predict biventricular circulation at birth.

Prosnitz AR, Drogosz M, Marshall AC, Wilkins-Haug LE, Benson CB, Sleeper LA, Tworetzky W, Friedman KG.

Prenat Diagn. 2018 Mar;38(4):286-292. doi: 10.1002/pd.5232. Epub 2018 Feb 26.


Myocardial injury in fetal aortic stenosis: Insights from amniotic fluid analysis.

Friedman KG, Sleeper LA, Fichorova RN, Weilnau T, Tworetzky W, Wilkins-Haug LE.

Prenat Diagn. 2018 Feb;38(3):190-195. doi: 10.1002/pd.5213. Epub 2018 Feb 6.


Fetal interventions for structural heart disease.

Schidlow DN, Freud L, Friedman K, Tworetzky W.

Echocardiography. 2017 Dec;34(12):1834-1841. doi: 10.1111/echo.13667. Review.


The boundaries of fetal cardiac intervention: Expand or tighten?

Gellis L, Tworetzky W.

Semin Fetal Neonatal Med. 2017 Dec;22(6):399-403. doi: 10.1016/j.siny.2017.08.006. Epub 2017 Sep 1. Review.


Improved technical success, postnatal outcome and refined predictors of outcome for fetal aortic valvuloplasty.

Friedman KG, Sleeper LA, Freud LR, Marshall AC, Godfrey ME, Drogosz M, Lafranchi T, Benson CB, Wilkins-Haug LE, Tworetzky W.

Ultrasound Obstet Gynecol. 2018 Aug;52(2):212-220. doi: 10.1002/uog.17530. Epub 2018 Jul 4.


Right Atrial Dysfunction in the Fetus with Severely Regurgitant Tricuspid Valve Disease: A Potential Source of Cardiovascular Compromise.

Howley LW, Khoo NS, Moon-Grady AJ, Patel SS, Alrais F, Tworetzky W, Colen T, Brooks P, Trines J, Ojala T, Hornberger LK.

J Am Soc Echocardiogr. 2017 Jun;30(6):579-588. doi: 10.1016/j.echo.2017.01.002. Epub 2017 Apr 11.


Neurodevelopmental Outcome in Children after Fetal Cardiac Intervention for Aortic Stenosis with Evolving Hypoplastic Left Heart Syndrome.

Laraja K, Sadhwani A, Tworetzky W, Marshall AC, Gauvreau K, Freud L, Hass C, Dunbar-Masterson C, Ware J, Lafranchi T, Wilkins-Haug L, Newburger JW.

J Pediatr. 2017 May;184:130-136.e4. doi: 10.1016/j.jpeds.2017.01.034. Epub 2017 Feb 21.


Umbilical Venous Catheter Malposition Is Associated with Necrotizing Enterocolitis in Premature Infants.

Sulemanji M, Vakili K, Zurakowski D, Tworetzky W, Fishman SJ, Kim HB.

Neonatology. 2017;111(4):337-343. doi: 10.1159/000451022. Epub 2017 Jan 17.


The Fetus with Ectopia Cordis: Experience and Expectations from Two Centers.

Escobar-Diaz MC, Sunderji S, Tworetzky W, Moon-Grady AJ.

Pediatr Cardiol. 2017 Mar;38(3):531-538. doi: 10.1007/s00246-016-1545-x. Epub 2016 Dec 19.


Cardiac output and blood flow redistribution in fetuses with D-loop transposition of the great arteries and intact ventricular septum: insights into pathophysiology.

Godfrey ME, Friedman KG, Drogosz M, Rudolph AM, Tworetzky W.

Ultrasound Obstet Gynecol. 2017 Nov;50(5):612-617. doi: 10.1002/uog.17370.


Assessment of Progressive Pathophysiology After Early Prenatal Diagnosis of the Ebstein Anomaly or Tricuspid Valve Dysplasia.

Selamet Tierney ES, McElhinney DB, Freud LR, Tworetzky W, Cuneo BF, Escobar-Diaz MC, Ikemba C, Kalish BT, Komarlu R, Levasseur SM, Puchalski MD, Satou GM, Silverman NH, Moon-Grady AJ.

Am J Cardiol. 2017 Jan 1;119(1):106-111. doi: 10.1016/j.amjcard.2016.09.022. Epub 2016 Sep 29.


Sonographic Pulmonary Abnormalities in Fetuses With Hypoplastic Left Heart Syndrome and Intact Atrial Septum Undergoing Attempted Atrial Septostomy In Utero.

Mackesy MM, Kalish BT, Tworetzky W, Sanders S, Al-Ibraheemi A, Wilkins-Haug L, Lock J, Marshall A, Benson CB.

Ultrasound Q. 2017 Mar;33(1):82-85. doi: 10.1097/RUQ.0000000000000247.


Assessment of the Melody valve in the mitral position in young children by echocardiography.

Freud LR, Marx GR, Marshall AC, Tworetzky W, Emani SM.

J Thorac Cardiovasc Surg. 2017 Jan;153(1):153-160.e1. doi: 10.1016/j.jtcvs.2016.07.017. Epub 2016 Jul 25.


Detection and successful treatment of emergent anti-SSA-mediated fetal atrioventricular block.

Cuneo BF, Ambrose SE, Tworetzky W.

Am J Obstet Gynecol. 2016 Oct;215(4):527-8. doi: 10.1016/j.ajog.2016.07.002. Epub 2016 Jul 12. No abstract available.


Detection and successful treatment of emergent anti-SSA mediated fetal atrioventricular block.

Cuneo BF, Ambrose SE, Tworetzky W.

Am J Obstet Gynecol. 2016 Jul 9. pii: S0002-9378(16)30439-2. doi: 10.1016/j.ajog.2016.07.006. [Epub ahead of print] No abstract available.


Cardiac Findings in the Fetus with Cerebral Arteriovenous Malformation Are Associated with Adverse Outcome.

Godfrey ME, Tworetzky W, Morash D, Friedman KG.

Fetal Diagn Ther. 2017;41(2):108-114. doi: 10.1159/000446432. Epub 2016 Jun 3.


Brain Injury in Neonates with Complex Congenital Heart Disease: What Is the Predictive Value of MRI in the Fetal Period?

Brossard-Racine M, du Plessis A, Vezina G, Robertson R, Donofrio M, Tworetzky W, Limperopoulos C.

AJNR Am J Neuroradiol. 2016 Jul;37(7):1338-46. doi: 10.3174/ajnr.A4716. Epub 2016 Mar 17.


Fetal interventions for congenital heart disease.

Freud LR, Tworetzky W.

Curr Opin Pediatr. 2016 Apr;28(2):156-62. doi: 10.1097/MOP.0000000000000331. Review.


International Fetal Cardiac Intervention Registry: A Worldwide Collaborative Description and Preliminary Outcomes.

Moon-Grady AJ, Morris SA, Belfort M, Chmait R, Dangel J, Devlieger R, Emery S, Frommelt M, Galindo A, Gelehrter S, Gembruch U, Grinenco S, Habli M, Herberg U, Jaeggi E, Kilby M, Kontopoulos E, Marantz P, Miller O, Otaño L, Pedra C, Pedra S, Pruetz J, Quintero R, Ryan G, Sharland G, Simpson J, Vlastos E, Tworetzky W, Wilkins-Haug L, Oepkes D; International Fetal Cardiac Intervention Registry.

J Am Coll Cardiol. 2015 Jul 28;66(4):388-99. doi: 10.1016/j.jacc.2015.05.037.


Outcomes and Predictors of Perinatal Mortality in Fetuses With Ebstein Anomaly or Tricuspid Valve Dysplasia in the Current Era: A Multicenter Study.

Freud LR, Escobar-Diaz MC, Kalish BT, Komarlu R, Puchalski MD, Jaeggi ET, Szwast AL, Freire G, Levasseur SM, Kavanaugh-McHugh A, Michelfelder EC, Moon-Grady AJ, Donofrio MT, Howley LW, Tierney ES, Cuneo BF, Morris SA, Pruetz JD, van der Velde ME, Kovalchin JP, Ikemba CM, Vernon MM, Samai C, Satou GM, Gotteiner NL, Phoon CK, Silverman NH, McElhinney DB, Tworetzky W.

Circulation. 2015 Aug 11;132(6):481-9. doi: 10.1161/CIRCULATIONAHA.115.015839. Epub 2015 Jun 9.


Left Ventricular Remodeling and Function in Children with Biventricular Circulation After Fetal Aortic Valvuloplasty.

Friedman KG, Freud L, Escobar-Diaz M, Banka P, Emani S, Tworetzky W.

Pediatr Cardiol. 2015 Oct;36(7):1502-9. doi: 10.1007/s00246-015-1193-6. Epub 2015 May 15.


Prenatal diagnosis of transposition of the great arteries over a 20-year period: improved but imperfect.

Escobar-Diaz MC, Freud LR, Bueno A, Brown DW, Friedman KG, Schidlow D, Emani S, Del Nido PJ, Tworetzky W.

Ultrasound Obstet Gynecol. 2015 Jun;45(6):678-82. doi: 10.1002/uog.14751. Epub 2015 Apr 30.


Low rate of prenatal diagnosis among neonates with critical aortic stenosis: insight into the natural history in utero.

Freud LR, Moon-Grady A, Escobar-Diaz MC, Gotteiner NL, Young LT, McElhinney DB, Tworetzky W.

Ultrasound Obstet Gynecol. 2015 Mar;45(3):326-32. doi: 10.1002/uog.14667. Epub 2015 Jan 28.


Fetal aortic valvuloplasty for evolving hypoplastic left heart syndrome: postnatal outcomes of the first 100 patients.

Freud LR, McElhinney DB, Marshall AC, Marx GR, Friedman KG, del Nido PJ, Emani SM, Lafranchi T, Silva V, Wilkins-Haug LE, Benson CB, Lock JE, Tworetzky W.

Circulation. 2014 Aug 19;130(8):638-45. doi: 10.1161/CIRCULATIONAHA.114.009032. Epub 2014 Jul 22.


Perinatal outcome after prenatal diagnosis of single-ventricle cardiac defects.

Beroukhim RS, Gauvreau K, Benavidez OJ, Baird CW, LaFranchi T, Tworetzky W.

Ultrasound Obstet Gynecol. 2015 Jun;45(6):657-63. doi: 10.1002/uog.14634. Epub 2015 Apr 23.


Perinatal and infant outcomes of prenatal diagnosis of heterotaxy syndrome (asplenia and polysplenia).

Escobar-Diaz MC, Friedman K, Salem Y, Marx GR, Kalish BT, Lafranchi T, Rathod RH, Emani S, Geva T, Tworetzky W.

Am J Cardiol. 2014 Aug 15;114(4):612-7. doi: 10.1016/j.amjcard.2014.05.042. Epub 2014 Jun 6.


Percutaneous fetal cardiac interventions for structural heart disease.

Schidlow DN, Tworetzky W, Wilkins-Haug LE.

Am J Perinatol. 2014 Aug;31(7):629-36. doi: 10.1055/s-0034-1383884. Epub 2014 Jun 12. Review.


Left ventricular diastolic function and characteristics in fetal aortic stenosis.

Friedman KG, Schidlow D, Freud L, Escobar-Diaz M, Tworetzky W.

Am J Cardiol. 2014 Jul 1;114(1):122-7. doi: 10.1016/j.amjcard.2014.04.013. Epub 2014 Apr 18.


Diagnosis and treatment of fetal cardiac disease: a scientific statement from the American Heart Association.

Donofrio MT, Moon-Grady AJ, Hornberger LK, Copel JA, Sklansky MS, Abuhamad A, Cuneo BF, Huhta JC, Jonas RA, Krishnan A, Lacey S, Lee W, Michelfelder EC Sr, Rempel GR, Silverman NH, Spray TL, Strasburger JF, Tworetzky W, Rychik J; American Heart Association Adults With Congenital Heart Disease Joint Committee of the Council on Cardiovascular Disease in the Young and Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and Council on Cardiovascular and Stroke Nursing.

Circulation. 2014 May 27;129(21):2183-242. doi: 10.1161/01.cir.0000437597.44550.5d. Epub 2014 Apr 24. Review. Erratum in: Circulation. 2014 May 27;129(21):e512.


Perinatal outcome in fetuses with heterotaxy syndrome and atrioventricular block or bradycardia.

Escobar-Diaz MC, Tworetzky W, Friedman K, Lafranchi T, Fynn-Thompson F, Alexander ME, Mah DY.

Pediatr Cardiol. 2014 Aug;35(6):906-13. doi: 10.1007/s00246-014-0874-x. Epub 2014 Feb 9.


Ventricular strain in fetuses with aortic stenosis and evolving hypoplastic left heart syndrome before and after prenatal aortic valvuloplasty.

Ishii T, McElhinney DB, Harrild DM, Marcus EN, Sahn DJ, Truong U, Tworetzky W.

Fetal Diagn Ther. 2014;35(1):18-26. doi: 10.1159/000341717. Epub 2013 Nov 19.


Biventricular conversion after single ventricle palliation in patients with small left heart structures: short-term outcomes.

Kalish BT, Banka P, Lafranchi T, Tworetzky W, Del Nido P, Emani SM.

Ann Thorac Surg. 2013 Oct;96(4):1406-1412. doi: 10.1016/j.athoracsur.2013.05.060. Epub 2013 Jul 31.


Midgestation fetal pulmonary annulus size is predictive of outcome in tetralogy of fallot.

Friedman K, Balasubramanian S, Tworetzky W.

Congenit Heart Dis. 2014 May-Jun;9(3):187-93. doi: 10.1111/chd.12120. Epub 2013 Jul 3.


Technical challenges of atrial septal stent placement in fetuses with hypoplastic left heart syndrome and intact atrial septum.

Kalish BT, Tworetzky W, Benson CB, Wilkins-Haug L, Mizrahi-Arnaud A, McElhinney DB, Lock JE, Marshall AC.

Catheter Cardiovasc Interv. 2014 Jul 1;84(1):77-85. doi: 10.1002/ccd.25098. Epub 2014 Apr 7.


Staged left ventricular recruitment after single-ventricle palliation in patients with borderline left heart hypoplasia.

Emani SM, McElhinney DB, Tworetzky W, Myers PO, Schroeder B, Zurakowski D, Pigula FA, Marx GR, Lock JE, del Nido PJ.

J Am Coll Cardiol. 2012 Nov 6;60(19):1966-74. doi: 10.1016/j.jacc.2012.07.041. Epub 2012 Oct 10.


Delayed cortical development in fetuses with complex congenital heart disease.

Clouchoux C, du Plessis AJ, Bouyssi-Kobar M, Tworetzky W, McElhinney DB, Brown DW, Gholipour A, Kudelski D, Warfield SK, McCarter RJ, Robertson RL Jr, Evans AC, Newburger JW, Limperopoulos C.

Cereb Cortex. 2013 Dec;23(12):2932-43. doi: 10.1093/cercor/bhs281. Epub 2012 Sep 12.


Hypoplastic left heart syndrome: current considerations and expectations.

Feinstein JA, Benson DW, Dubin AM, Cohen MS, Maxey DM, Mahle WT, Pahl E, Villafañe J, Bhatt AB, Peng LF, Johnson BA, Marsden AL, Daniels CJ, Rudd NA, Caldarone CA, Mussatto KA, Morales DL, Ivy DD, Gaynor JW, Tweddell JS, Deal BJ, Furck AK, Rosenthal GL, Ohye RG, Ghanayem NS, Cheatham JP, Tworetzky W, Martin GR.

J Am Coll Cardiol. 2012 Jan 3;59(1 Suppl):S1-42. doi: 10.1016/j.jacc.2011.09.022. Review. Erratum in: J Am Coll Cardiol. 2012 Jan 31;59(5):544.


Ebstein's malformation of the tricuspid valve: short-term outcomes of the "cone procedure" versus conventional surgery.

Vogel M, Marx GR, Tworetzky W, Cecchin F, Graham D, Mayer JE, Pigula FA, Bacha EA, Del Nido PJ.

Congenit Heart Dis. 2012 Jan-Feb;7(1):50-8. doi: 10.1111/j.1747-0803.2011.00603.x. Epub 2011 Dec 18.


Circumferential and longitudinal ventricular strain in the normal human fetus.

Ishii T, McElhinney DB, Harrild DM, Marcus EN, Sahn DJ, Truong U, Tworetzky W.

J Am Soc Echocardiogr. 2012 Jan;25(1):105-11. doi: 10.1016/j.echo.2011.09.016. Epub 2011 Oct 26.


Left ventricular function and geometry in fetuses with severe tricuspid regurgitation.

Ishii T, Tworetzky W, Harrild DM, Marcus EN, McElhinney DB.

Ultrasound Obstet Gynecol. 2012 Jul;40(1):55-61. doi: 10.1002/uog.10115. Epub 2012 Jun 15.


Postnatal left ventricular diastolic function after fetal aortic valvuloplasty.

Friedman KG, Margossian R, Graham DA, Harrild DM, Emani SM, Wilkins-Haug LE, McElhinney DB, Tworetzky W.

Am J Cardiol. 2011 Aug 15;108(4):556-60. doi: 10.1016/j.amjcard.2011.03.085. Epub 2011 May 31.


Early reintervention on the pulmonary arteries and right ventricular outflow tract after neonatal or early infant repair of truncus arteriosus using homograft conduits.

Lund AM, Vogel M, Marshall AC, Emani SM, Pigula FA, Tworetzky W, McElhinney DB.

Am J Cardiol. 2011 Jul 1;108(1):106-13. doi: 10.1016/j.amjcard.2011.03.006. Epub 2011 Apr 29.


2010 Report from the ISPD Special Interest Group fetal therapy: fetal cardiac interventions.

Oepkes D, Moon-Grady AJ, Wilkins-Haug L, Tworetzky W, Arzt W, Devlieger R.

Prenat Diagn. 2011 Mar;31(3):249-51. doi: 10.1002/pd.2696. Epub 2011 Feb 1. No abstract available.


The Fetus as a Cardiac Patient: Assessment and Therapy of Cardiovascular Pathology before Birth.

Moon-Grady AJ, Hirose S, Kesby G, Menahem S, Tworetzky W.

Int J Pediatr. 2010;2010:974520. doi: 10.1155/2010/974520. Epub 2010 Dec 29. No abstract available.


Aortic stenosis and severe mitral regurgitation in the fetus resulting in giant left atrium and hydrops: pathophysiology, outcomes, and preliminary experience with pre-natal cardiac intervention.

Vogel M, McElhinney DB, Wilkins-Haug LE, Marshall AC, Benson CB, Juraszek AL, Silva V, Lock JE, Marx GR, Tworetzky W.

J Am Coll Cardiol. 2011 Jan 18;57(3):348-55. doi: 10.1016/j.jacc.2010.08.636.


Assessment of left ventricular endocardial fibroelastosis in fetuses with aortic stenosis and evolving hypoplastic left heart syndrome.

McElhinney DB, Vogel M, Benson CB, Marshall AC, Wilkins-Haug LE, Silva V, Tworetzky W.

Am J Cardiol. 2010 Dec 15;106(12):1792-7. doi: 10.1016/j.amjcard.2010.08.022.


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