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Items: 1 to 50 of 72

1.

Development of an orthotopic canine prostate cancer model expressing human GRPr.

Tweedle MF, Ding H, Drost WT, Dowell J, Spain J, Joseph M, Elshafae SM, Menendez MI, Gong L, Kothandaraman S, Dirksen WP, Wright CL, Bahnson R, Knopp MV, Rosol TJ.

Prostate. 2018 Jul 11. doi: 10.1002/pros.23686. [Epub ahead of print]

PMID:
29992622
2.

Linker engineering in anti-TAG-72 antibody fragments optimizes biophysical properties, serum half-life, and high-specificity tumor imaging.

Long NE, Sullivan BJ, Ding H, Doll S, Ryan MA, Hitchcock CL, Martin EW Jr, Kumar K, Tweedle MF, Magliery TJ.

J Biol Chem. 2018 Jun 8;293(23):9030-9040. doi: 10.1074/jbc.RA118.002538. Epub 2018 Apr 18.

PMID:
29669811
3.

Science to Practice: Will Gadolinium Chelates Be Replaced by Iron Chelates in MR Imaging?

Tweedle MF.

Radiology. 2018 Feb;286(2):409-411. doi: 10.1148/radiol.2017172305.

PMID:
29356647
4.

A 3E8.scFv.Cys-IR800 Conjugate Targeting TAG-72 in an Orthotopic Colorectal Cancer Model.

Gong L, Ding H, Long NE, Sullivan BJ, Martin EW Jr, Magliery TJ, Tweedle MF.

Mol Imaging Biol. 2018 Feb;20(1):47-54. doi: 10.1007/s11307-017-1096-4.

5.

Balancing the intermolecular forces in peptide amphiphiles for controlling self-assembly transitions.

Buettner CJ, Wallace AJ, Ok S, Manos AA, Nicholl MJ, Ghosh A, Tweedle MF, Goldberger JE.

Org Biomol Chem. 2017 Jun 21;15(24):5220-5226. doi: 10.1039/c7ob00875a.

PMID:
28594046
6.

Biological Evaluation of a Fluorescent-Imaging Agent for Medullary Thyroid Cancer in an Orthotopic Model.

Rossfeld KK, Justiniano SE, Ding H, Gong L, Kothandaraman S, Sawant D, Saji M, Wright CL, Kirschner LS, Ringel MD, Tweedle MF, Phay JE.

J Clin Endocrinol Metab. 2017 Sep 1;102(9):3268-3277. doi: 10.1210/jc.2017-00573.

PMID:
28591772
7.

Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection.

Tummers WS, Warram JM, Tipirneni KE, Fengler J, Jacobs P, Shankar L, Henderson L, Ballard B, Pogue BW, Weichert JP, Bouvet M, Sorger J, Contag CH, Frangioni JV, Tweedle MF, Basilion JP, Gambhir SS, Rosenthal EL.

Cancer Res. 2017 May 1;77(9):2197-2206. doi: 10.1158/0008-5472.CAN-16-3217. Epub 2017 Apr 20. Erratum in: Cancer Res. 2018 Feb 15;78(4):1123.

8.

The use of gadolinium-based contrast agents should be discontinued until proven safe.

Branch SM, Tweedle MF, Orton CG.

Med Phys. 2017 Jul;44(7):3371-3374. doi: 10.1002/mp.12212. Epub 2017 Apr 17. No abstract available.

PMID:
28295396
9.

Optical Surgical Navigation for Precision in Tumor Resections.

Harmsen S, Teraphongphom N, Tweedle MF, Basilion JP, Rosenthal EL.

Mol Imaging Biol. 2017 Jun;19(3):357-362. doi: 10.1007/s11307-017-1054-1. Review.

10.

Gadolinium deposition: Is it chelated or dissociated gadolinium? How can we tell?

Tweedle MF.

Magn Reson Imaging. 2016 Dec;34(10):1377-1382. doi: 10.1016/j.mri.2016.09.003. Epub 2016 Sep 30. Review.

PMID:
27697544
11.

Advancing theranostics with tumor-targeting peptides for precision otolaryngology.

Wright CL, Pan Q, Knopp MV, Tweedle MF.

World J Otorhinolaryngol Head Neck Surg. 2016 Jul 26;2(2):98-108. doi: 10.1016/j.wjorl.2016.05.006. eCollection 2016 Jun. Review.

12.

A Wearable Goggle Navigation System for Dual-Mode Optical and Ultrasound Localization of Suspicious Lesions: Validation Studies Using Tissue-Simulating Phantoms and an Ex Vivo Human Breast Tissue Model.

Zhang Z, Pei J, Wang D, Gan Q, Ye J, Yue J, Wang B, Povoski SP, Martin EW Jr, Hitchcock CL, Yilmaz A, Tweedle MF, Shao P, Xu RX.

PLoS One. 2016 Jul 1;11(7):e0157854. doi: 10.1371/journal.pone.0157854. eCollection 2016.

13.

A human GRPr-transfected Ace-1 canine prostate cancer model in mice.

Ding H, Kothandaraman S, Gong L, Williams MM, Dirksen WP, Rosol TJ, Tweedle MF.

Prostate. 2016 Jun;76(9):783-95. doi: 10.1002/pros.23172. Epub 2016 Mar 4.

14.

Gastrin-releasing peptide receptor (GRPr) promotes EMT, growth, and invasion in canine prostate cancer.

Elshafae SM, Hassan BB, Supsavhad W, Dirksen WP, Camiener RY, Ding H, Tweedle MF, Rosol TJ.

Prostate. 2016 Jun;76(9):796-809. doi: 10.1002/pros.23154. Epub 2016 Mar 4.

15.

Successful Translation of Fluorescence Navigation During Oncologic Surgery: A Consensus Report.

Rosenthal EL, Warram JM, de Boer E, Basilion JP, Biel MA, Bogyo M, Bouvet M, Brigman BE, Colson YL, DeMeester SR, Gurtner GC, Ishizawa T, Jacobs PM, Keereweer S, Liao JC, Nguyen QT, Olson JM, Paulsen KD, Rieves D, Sumer BD, Tweedle MF, Vahrmeijer AL, Weichert JP, Wilson BC, Zenn MR, Zinn KR, van Dam GM.

J Nucl Med. 2016 Jan;57(1):144-50. doi: 10.2967/jnumed.115.158915. Epub 2015 Oct 8.

16.

Theranostic Imaging of Yttrium-90.

Wright CL, Zhang J, Tweedle MF, Knopp MV, Hall NC.

Biomed Res Int. 2015;2015:481279. doi: 10.1155/2015/481279. Epub 2015 May 28. Review.

17.

Residual or retained gadolinium: practical implications for radiologists and our patients.

Kanal E, Tweedle MF.

Radiology. 2015 Jun;275(3):630-4. doi: 10.1148/radiol.2015150805. Epub 2015 May 5. No abstract available.

PMID:
25942418
18.

Probing peptide amphiphile self-assembly in blood serum.

Ghosh A, Buettner CJ, Manos AA, Wallace AJ, Tweedle MF, Goldberger JE.

Biomacromolecules. 2014 Dec 8;15(12):4488-94. doi: 10.1021/bm501311g. Epub 2014 Nov 12.

19.

A high-affinity near-infrared fluorescent probe to target bombesin receptors.

Shrivastava A, Ding H, Kothandaraman S, Wang SH, Gong L, Williams M, Milum K, Zhang S, Tweedle MF.

Mol Imaging Biol. 2014 Oct;16(5):661-9. doi: 10.1007/s11307-014-0727-2.

20.

Development of a calcium-sensing receptor molecular imaging agent.

Yusof AM, Kothandaraman S, Zhang X, Saji M, Ringel MD, Tweedle MF, Phay JE.

Surgery. 2013 Dec;154(6):1378-84; discussion 1384. doi: 10.1016/j.surg.2013.06.044.

21.

Site specific discrete PEGylation of (124)I-labeled mCC49 Fab' fragments improves tumor MicroPET/CT imaging in mice.

Ding H, Carlton MM, Povoski SP, Milum K, Kumar K, Kothandaraman S, Hinkle GH, Colcher D, Brody R, Davis PD, Pokora A, Phelps M, Martin EW Jr, Tweedle MF.

Bioconjug Chem. 2013 Nov 20;24(11):1945-54. doi: 10.1021/bc400375f. Epub 2013 Oct 31.

22.

Identification of ideal peptides for heterovalent ligands.

Shrivastava A, von Wronski M, Tweedle MF, Nunn AD.

Methods Mol Biol. 2014;1088:97-105. doi: 10.1007/978-1-62703-673-3_7.

PMID:
24146399
23.

Localization of CaSR antagonists in CaSR-expressing medullary thyroid cancer.

Ding H, Yusof AM, Kothandaraman S, Saji M, Wang C, Kumar K, Milum K, Carleton M, Pan X, Ringel MD, Tweedle MF, Phay JE.

J Clin Endocrinol Metab. 2013 Nov;98(11):E1722-9. doi: 10.1210/jc.2013-1756. Epub 2013 Sep 12.

24.

Heterobivalent dual-target probe for targeting GRP and Y1 receptors on tumor cells.

Shrivastava A, Wang SH, Raju N, Gierach I, Ding H, Tweedle MF.

Bioorg Med Chem Lett. 2013 Feb 1;23(3):687-92. doi: 10.1016/j.bmcl.2012.11.110. Epub 2012 Dec 5.

25.

Fine-tuning the pH trigger of self-assembly.

Ghosh A, Haverick M, Stump K, Yang X, Tweedle MF, Goldberger JE.

J Am Chem Soc. 2012 Feb 29;134(8):3647-50. doi: 10.1021/ja211113n. Epub 2012 Feb 13.

26.

Synthesis, in vitro evaluation, and in vivo metabolism of fluor/quencher compounds containing IRDye 800CW and Black Hole Quencher-3 (BHQ-3).

Linder KE, Metcalfe E, Nanjappan P, Arunachalam T, Ramos K, Skedzielewski TM, Marinelli ER, Tweedle MF, Nunn AD, Swenson RE.

Bioconjug Chem. 2011 Jul 20;22(7):1287-97. doi: 10.1021/bc100457s. Epub 2011 Jun 27.

PMID:
21639144
27.

Drug-loaded biodegradable microspheres for image-guided combinatory epigenetic therapy in cells.

Xu RX, Xu JS, Zuo T, Shen R, Huang TH, Tweedle MF.

J Biomed Opt. 2011 Feb;16(2):020507. doi: 10.1117/1.3548878.

28.

177Lu-AMBA biodistribution, radiotherapeutic efficacy, imaging, and autoradiography in prostate cancer models with low GRP-R expression.

Maddalena ME, Fox J, Chen J, Feng W, Cagnolini A, Linder KE, Tweedle MF, Nunn AD, Lantry LE.

J Nucl Med. 2009 Dec;50(12):2017-24. doi: 10.2967/jnumed.109.064444. Epub 2009 Nov 12.

29.

Peptide-targeted diagnostics and radiotherapeutics.

Tweedle MF.

Acc Chem Res. 2009 Jul 21;42(7):958-68. doi: 10.1021/ar800215p.

PMID:
19552403
30.

Designer peptides: learning from nature.

Shrivastava A, Nunn AD, Tweedle MF.

Curr Pharm Des. 2009;15(6):675-81. Review.

PMID:
19199988
31.

Brain tumor enhancement in magnetic resonance imaging: dependency on the level of protein binding of applied contrast agents.

Wintersperger BJ, Runge VM, Tweedle MF, Jackson CB, Reiser MF.

Invest Radiol. 2009 Feb;44(2):89-94. doi: 10.1097/RLI.0b013e318191a334.

PMID:
19077910
32.

Synthesis, stabilization and formulation of [177Lu]Lu-AMBA, a systemic radiotherapeutic agent for Gastrin Releasing Peptide receptor positive tumors.

Chen J, Linder KE, Cagnolini A, Metcalfe E, Raju N, Tweedle MF, Swenson RE.

Appl Radiat Isot. 2008 Apr;66(4):497-505. doi: 10.1016/j.apradiso.2007.11.007. Epub 2007 Nov 19.

PMID:
18178448
33.

"Stability" of gadolinium chelates.

Tweedle MF.

Br J Radiol. 2007 Jul;80(955):583-4; author reply 584-5. No abstract available.

PMID:
17704319
34.

Binding of the C-terminal amino acids of VEGF121 directly with neuropilin-1 should be considered.

von Wronski MA, Tweedle MF, Nunn AD.

FASEB J. 2007 May;21(7):1292; author reply 1293. No abstract available.

PMID:
17470574
35.

Adventures in multivalency, the Harry S. Fischer memorial lecture CMR 2005; Evian, France.

Tweedle MF.

Contrast Media Mol Imaging. 2006 Jan-Feb;1(1):2-9.

PMID:
17193594
36.

177Lu-AMBA: Synthesis and characterization of a selective 177Lu-labeled GRP-R agonist for systemic radiotherapy of prostate cancer.

Lantry LE, Cappelletti E, Maddalena ME, Fox JS, Feng W, Chen J, Thomas R, Eaton SM, Bogdan NJ, Arunachalam T, Reubi JC, Raju N, Metcalfe EC, Lattuada L, Linder KE, Swenson RE, Tweedle MF, Nunn AD.

J Nucl Med. 2006 Jul;47(7):1144-52.

38.

Tuftsin binds neuropilin-1 through a sequence similar to that encoded by exon 8 of vascular endothelial growth factor.

von Wronski MA, Raju N, Pillai R, Bogdan NJ, Marinelli ER, Nanjappan P, Ramalingam K, Arunachalam T, Eaton S, Linder KE, Yan F, Pochon S, Tweedle MF, Nunn AD.

J Biol Chem. 2006 Mar 3;281(9):5702-10. Epub 2005 Dec 21.

39.

A distinct strategy to generate high-affinity peptide binders to receptor tyrosine kinases.

Shrivastava A, von Wronski MA, Sato AK, Dransfield DT, Sexton D, Bogdan N, Pillai R, Nanjappan P, Song B, Marinelli E, DeOliveira D, Luneau C, Devlin M, Muruganandam A, Abujoub A, Connelly G, Wu QL, Conley G, Chang Q, Tweedle MF, Ladner RC, Swenson RE, Nunn AD.

Protein Eng Des Sel. 2005 Sep;18(9):417-24. Epub 2005 Aug 8.

PMID:
16087652
40.

Polymethylated DOTA ligands. 2. Synthesis of rigidified lanthanide chelates and studies on the effect of alkyl substitution on conformational mobility and relaxivity.

Ranganathan RS, Raju N, Fan H, Zhang X, Tweedle MF, Desreux JF, Jacques V.

Inorg Chem. 2002 Dec 16;41(25):6856-66.

PMID:
12470084
41.

Polymethylated DOTA ligands. 1. Synthesis of rigidified ligands and studies on the effects of alkyl substitution on acid-base properties and conformational mobility.

Ranganathan RS, Pillai RK, Raju N, Fan H, Nguyen H, Tweedle MF, Desreux JF, Jacques V.

Inorg Chem. 2002 Dec 16;41(25):6846-55.

PMID:
12470083
42.

Using radiotracers to characterize magnetic resonance imaging contrast agents.

Tweedle MF.

Invest Radiol. 2002 Mar;37(3):107-13. Review. No abstract available.

PMID:
11882789
43.

Caenorhabditis elegans as an alternative animal species.

Williams PL, Anderson GL, Johnstone JL, Nunn AD, Tweedle MF, Wedeking P.

J Toxicol Environ Health A. 2000 Dec 29;61(8):641-7.

PMID:
11132694
44.

Synthesis, characterization, and imaging performance of a new class of macrocyclic hepatobiliary MR contrast agents.

Marinelli ER, Neubeck R, Song B, Wagler T, Ranganathan RS, Sukumaran K, Wedeking PW, Nunn A, Runge VM, Tweedle MF.

Invest Radiol. 2000 Jan;35(1):8-24.

PMID:
10639032
45.

Utilization of the nephrectomized mouse for determining threshold effects of MRI contrast agents.

Wedeking P, Shukla R, Kouch YT, Nunn AD, Tweedle MF.

Magn Reson Imaging. 1999 May;17(4):569-75.

PMID:
10231183
46.

New multimeric magnetic resonance imaging agents.

Ranganathan RS, Fernandez ME, Kang SI, Nunn AD, Ratsep PC, Pillai KM, Zhang X, Tweedle MF.

Invest Radiol. 1998 Nov;33(11):779-97.

PMID:
9818313
47.

A noninvasive method for monitoring renal status at bedside.

Tweedle MF, Zhang X, Fernandez M, Wedeking P, Nunn AD, Strauss HW.

Invest Radiol. 1997 Dec;32(12):802-5.

PMID:
9406021
48.

Can receptors be imaged with MRI agents?

Nunn AD, Linder KE, Tweedle MF.

Q J Nucl Med. 1997 Jun;41(2):155-62. Review.

PMID:
9203854
49.

The ProHance story: the making of a novel MRI contrast agent.

Tweedle MF.

Eur Radiol. 1997;7 Suppl 5:225-30.

PMID:
9370548
50.

Design of conformationally rigid dimeric MRI agents.

Shukla R, Fernandez M, Pillai RK, Ranganathan R, Ratsep PC, Zhang X, Tweedle MF.

Magn Reson Med. 1996 Jun;35(6):928-31.

PMID:
8744023

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