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Items: 1 to 50 of 82

1.

Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.

Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ.

Diabetes. 2002 Apr;51(4):966-76.

2.

In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain.

Fallon J, Reid S, Kinyamu R, Opole I, Opole R, Baratta J, Korc M, Endo TL, Duong A, Nguyen G, Karkehabadhi M, Twardzik D, Patel S, Loughlin S.

Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14686-91. Erratum in: Proc Natl Acad Sci U S A 2001 Jul 3;98(14):8157.

3.

Identification of rat prostatic steroid-binding protein as a target antigen of experimental autoimmune prostatitis: implications for prostate cancer therapy.

Liu KJ, Chatta GS, Twardzik DR, Vedvick TS, True LD, Spies AG, Cheever MA.

J Immunol. 1997 Jul 1;159(1):472-80.

PMID:
9200488
4.

Effects of retinol on activation of latent transforming growth factor-beta by isolated osteoclasts.

Bonewald LF, Oreffo RO, Lee CH, Park-Snyder S, Twardzik D, Mundy GR.

Endocrinology. 1997 Feb;138(2):657-66.

PMID:
9003000
5.

Acceleration of wound healing in aged rats by topical application of transforming growth factor-beta(1).

Puolakkainen PA, Reed MJ, Gombotz WR, Twardzik DR, Abrass IB, Sage HE.

Wound Repair Regen. 1995 Jul-Sep;3(3):330-9.

PMID:
17173560
6.

The enhancement in wound healing by transforming growth factor-beta 1 (TGF-beta 1) depends on the topical delivery system.

Puolakkainen PA, Twardzik DR, Ranchalis JE, Pankey SC, Reed MJ, Gombotz WR.

J Surg Res. 1995 Mar;58(3):321-9.

PMID:
7885030
7.

Increase of plasma transforming growth factor beta (TGF beta) during immunotherapy with IL-2.

Puolakkainen P, Twardzik D, Ranchalis J, Moroni M, Mandeli J, Paciucci PA.

Cancer Invest. 1995;13(6):583-9.

PMID:
7583707
8.

Latent transforming growth factor-beta is produced by chondrocytes and activated by extracellular matrix vesicles upon exposure to 1,25-(OH)2D3.

Boyan BD, Schwartz Z, Park-Snyder S, Dean DD, Yang F, Twardzik D, Bonewald LF.

J Biol Chem. 1994 Nov 11;269(45):28374-81.

9.

Novel delivery system for inducing quiescence in intestinal stem cells in rats by transforming growth factor beta 1.

Puolakkainen PA, Ranchalis JE, Gombotz WR, Hoffman AS, Mumper RJ, Twardzik DR.

Gastroenterology. 1994 Nov;107(5):1319-26.

PMID:
7926496
10.

Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta.

Hildebrand A, Romarís M, Rasmussen LM, Heinegård D, Twardzik DR, Border WA, Ruoslahti E.

Biochem J. 1994 Sep 1;302 ( Pt 2):527-34.

12.

Inhibition of interleukin-2 synthesis and interleukin-2 receptor alpha expression on T cells by a cell-free factor derived from a CD4+ regulatory T cell clone.

Okino T, Chakraborty NG, Stabach P, Twardzik DR, Padula SJ, Mukherji B.

Clin Immunol Immunopathol. 1993 Sep;68(3):256-62.

PMID:
8103719
13.

The effect of sterilization on transforming growth factor beta isolated from demineralized human bone.

Puolakkainen PA, Ranchalis JE, Strong DM, Twardzik DR.

Transfusion. 1993 Aug;33(8):679-85.

PMID:
8342237
14.
15.

Transforming growth factor beta as a virulence mechanism for Leishmania braziliensis.

Barral A, Barral-Netto M, Yong EC, Brownell CE, Twardzik DR, Reed SG.

Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3442-6.

16.

Transforming growth factor-beta in leishmanial infection: a parasite escape mechanism.

Barral-Netto M, Barral A, Brownell CE, Skeiky YA, Ellingsworth LR, Twardzik DR, Reed SG.

Science. 1992 Jul 24;257(5069):545-8.

PMID:
1636092
17.

Transforming growth factor beta has neurotrophic actions on sensory neurons in vitro and is synergistic with nerve growth factor.

Chalazonitis A, Kalberg J, Twardzik DR, Morrison RS, Kessler JA.

Dev Biol. 1992 Jul;152(1):121-32.

PMID:
1378411
18.

Transforming growth factor alpha, but not epidermal growth factor, promotes the survival of sensory neurons in vitro.

Chalazonitis A, Kessler JA, Twardzik DR, Morrison RS.

J Neurosci. 1992 Feb;12(2):583-94.

19.

Adoptive transfer of activated human autologous macrophages results in regression of transplanted human melanoma cells in SCID mice.

Chakraborty NG, Okino T, Stabach P, Padula SJ, Yamase H, Morse E, Sha'afi RI, Twardzik DR, Shultz LJ, Mukherji B.

In Vivo. 1991 Nov-Dec;5(6):609-14.

PMID:
1810447
20.
21.

Production of transforming growth factor beta 1 during repair of arterial injury.

Majesky MW, Lindner V, Twardzik DR, Schwartz SM, Reidy MA.

J Clin Invest. 1991 Sep;88(3):904-10.

22.
23.

Assessment of biological activity of synthetic fragments of transforming growth factor alpha.

Schultz G, Twardzik D.

Methods Enzymol. 1991;198:200-13. No abstract available.

PMID:
1857219
24.

Role of cytokines in inflammation and autoimmunity.

Talmadge JE, Twardzik DR.

Agents Actions Suppl. 1991;35:135-41. No abstract available.

PMID:
1781418
25.

Autologous melanoma-induced activation of regulatory T cells that suppress cytotoxic response.

Chakraborty NG, Twardzik DR, Sivanandham M, Ergin MT, Hellstrom KE, Mukherji B.

J Immunol. 1990 Oct 1;145(7):2359-64.

PMID:
1975829
26.

Localization of cells containing transforming growth factor-alpha precursor immunoreactivity in the basal ganglia of the adult rat brain.

Fallon JH, Annis CM, Gentry LE, Twardzik DR, Loughlin SE.

Growth Factors. 1990;2(2-3):241-50.

PMID:
2340185
27.

Gamma-interferon-induced activation of latent transforming growth factor-beta by human monocytes.

Twardzik DR, Mikovits JA, Ranchalis JE, Purchio AF, Ellingsworth L, Ruscetti FW.

Ann N Y Acad Sci. 1990;593:276-84. No abstract available.

PMID:
2115757
28.

Inhibition and promotion of differentiated-like phenotype of a human lung carcinoma in athymic mice by natural and recombinant forms of transforming growth factor-beta.

Twardzik DR, Ranchalis JE, McPherson JM, Ogawa Y, Gentry L, Purchio A, Plata E, Todaro GJ.

J Natl Cancer Inst. 1989 Aug 2;81(15):1182-5.

PMID:
2746671
29.

Ovarian transforming growth factor-beta (TGF beta): cellular site(s), and mechanism(s) of action.

Adashi EY, Resnick CE, Hernandez ER, May JV, Purchio AF, Twardzik DR.

Mol Cell Endocrinol. 1989 Feb;61(2):247-56.

PMID:
2492958
30.
31.

Transforming growth factor alpha (TGF alpha) induction of C-FOS and C-MYC expression in C3H 10T1/2 cells.

Cutry AF, Kinniburgh AJ, Twardzik DR, Wenner CE.

Biochem Biophys Res Commun. 1988 Apr 15;152(1):216-22.

PMID:
3258745
32.

Assessment of biological activity of synthetic fragments of transforming growth factor-alpha.

Darlak K, Franklin G, Woost P, Sonnenfeld E, Twardzik D, Spatola A, Schultz G.

J Cell Biochem. 1988 Apr;36(4):341-52.

PMID:
2897968
33.

Deletion of the vaccinia virus growth factor gene reduces virus virulence.

Buller RM, Chakrabarti S, Cooper JA, Twardzik DR, Moss B.

J Virol. 1988 Mar;62(3):866-74.

34.

Transforming growth factor-beta 2: cDNA cloning and sequence analysis.

Madisen L, Webb NR, Rose TM, Marquardt H, Ikeda T, Twardzik D, Seyedin S, Purchio AF.

DNA. 1988 Jan-Feb;7(1):1-8.

PMID:
3162414
35.

Bone-derived and recombinant transforming growth factor beta's are potent inhibitors of tumor cell growth.

Ranchalis JE, Gentry L, Ogawa Y, Seyedin SM, McPherson J, Purchio A, Twardzik DR.

Biochem Biophys Res Commun. 1987 Oct 29;148(2):783-9.

PMID:
3479985
36.

Type 1 transforming growth factor beta: amplified expression and secretion of mature and precursor polypeptides in Chinese hamster ovary cells.

Gentry LE, Webb NR, Lim GJ, Brunner AM, Ranchalis JE, Twardzik DR, Lioubin MN, Marquardt H, Purchio AF.

Mol Cell Biol. 1987 Oct;7(10):3418-27.

37.

Ovarian transforming growth factor-alpha gene expression: immunohistochemical localization to the theca-interstitial cells.

Kudlow JE, Kobrin MS, Purchio AF, Twardzik DR, Hernandez ER, Asa SL, Adashi EY.

Endocrinology. 1987 Oct;121(4):1577-9.

PMID:
3477453
38.

Cloning and sequence analysis of simian transforming growth factor-beta cDNA.

Sharples K, Plowman GD, Rose TM, Twardzik DR, Purchio AF.

DNA. 1987 Jun;6(3):239-44.

PMID:
3474130
39.

Expression and characterization of transforming growth factor alpha precursor protein in transfected mammalian cells.

Gentry LE, Twardzik DR, Lim GJ, Ranchalis JE, Lee DC.

Mol Cell Biol. 1987 May;7(5):1585-91.

40.

Epithelial wound healing enhanced by transforming growth factor-alpha and vaccinia growth factor.

Schultz GS, White M, Mitchell R, Brown G, Lynch J, Twardzik DR, Todaro GJ.

Science. 1987 Jan 16;235(4786):350-2.

PMID:
3492044
41.

Vaccinia growth factor: newest member of the family of growth modulators which utilize the membrane receptor for EGF.

Twardzik DR, Ranchalis JE, Moss B, Todaro GJ.

Acta Neurochir Suppl (Wien). 1987;41:104-9.

PMID:
3502224
42.

Synthesis of an active hybrid growth factor (GF) in bacteria: transforming GF-alpha/vaccinia GF fusion protein.

Purchio AF, Twardzik DR, Bruce AG, Wizental L, Madisen L, Ranchalis JE, Hu SL, Todaro G.

Gene. 1987;60(2-3):175-82.

PMID:
3327748
43.
44.

Inhibition of endothelial regeneration by type-beta transforming growth factor from platelets.

Heimark RL, Twardzik DR, Schwartz SM.

Science. 1986 Sep 5;233(4768):1078-80.

PMID:
3461562
46.
47.
48.

Vaccinia virus-infected cells release a novel polypeptide functionally related to transforming and epidermal growth factors.

Twardzik DR, Brown JP, Ranchalis JE, Todaro GJ, Moss B.

Proc Natl Acad Sci U S A. 1985 Aug;82(16):5300-4.

49.

Stimulation of bone resorption in vitro by synthetic transforming growth factor-alpha.

Ibbotson KJ, Twardzik DR, D'Souza SM, Hargreaves WR, Todaro GJ, Mundy GR.

Science. 1985 May 24;228(4702):1007-9.

PMID:
3859011
50.

Comparison of growth factors functionally related to epidermal growth factor in the urine of normal and human tumor-bearing athymic mice.

Twardzik DR, Kimball ES, Sherwin SA, Ranchalis JE, Todaro GJ.

Cancer Res. 1985 May;45(5):1934-9.

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