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Items: 14


The neuronal ceroid lipofuscinosis protein Cln7 functions in the postsynaptic cell to regulate synapse development.

Connolly KJ, O'Hare MB, Mohammed A, Aitchison KM, Anthoney NC, Taylor MJ, Stewart BA, Tuxworth RI, Tear G.

Sci Rep. 2019 Oct 30;9(1):15592. doi: 10.1038/s41598-019-51588-w.


Continuous tracking of startled Drosophila as an alternative to the negative geotaxis climbing assay.

Taylor MJ, Tuxworth RI.

J Neurogenet. 2019 Sep;33(3):190-198. doi: 10.1080/01677063.2019.1634065. Epub 2019 Jul 10.


Dysregulation of autophagy as a common mechanism in lysosomal storage diseases.

Seranova E, Connolly KJ, Zatyka M, Rosenstock TR, Barrett T, Tuxworth RI, Sarkar S.

Essays Biochem. 2017 Dec 12;61(6):733-749. doi: 10.1042/EBC20170055. Print 2017 Dec 12. Review.


in vivo localization of the neuronal ceroid lipofuscinosis proteins, CLN3 and CLN7, at endogenous expression levels.

Mohammed A, O'Hare MB, Warley A, Tear G, Tuxworth RI.

Neurobiol Dis. 2017 Jul;103:123-132. doi: 10.1016/j.nbd.2017.03.015. Epub 2017 Mar 29.


The neuronal ceroid lipofuscinoses: Opportunities from model systems.

Faller KM, Gutierrez-Quintana R, Mohammed A, Rahim AA, Tuxworth RI, Wager K, Bond M.

Biochim Biophys Acta. 2015 Oct;1852(10 Pt B):2267-78. doi: 10.1016/j.bbadis.2015.04.022. Epub 2015 Apr 29. Review.


Modification of the Drosophila model of in vivo Tau toxicity reveals protective phosphorylation by GSK3β.

Povellato G, Tuxworth RI, Hanger DP, Tear G.

Biol Open. 2014 Jan 15;3(1):1-11. doi: 10.1242/bio.20136692.


The Batten disease gene CLN3 is required for the response to oxidative stress.

Tuxworth RI, Chen H, Vivancos V, Carvajal N, Huang X, Tear G.

Hum Mol Genet. 2011 May 15;20(10):2037-47. doi: 10.1093/hmg/ddr088. Epub 2011 Mar 3.


Interactions between the juvenile Batten disease gene, CLN3, and the Notch and JNK signalling pathways.

Tuxworth RI, Vivancos V, O'Hare MB, Tear G.

Hum Mol Genet. 2009 Feb 15;18(4):667-78. doi: 10.1093/hmg/ddn396. Epub 2008 Nov 21.


Identification of a myosin VII-talin complex.

Tuxworth RI, Stephens S, Ryan ZC, Titus MA.

J Biol Chem. 2005 Jul 15;280(28):26557-64. Epub 2005 Apr 11.


A role for myosin VII in dynamic cell adhesion.

Tuxworth RI, Weber I, Wessels D, Addicks GC, Soll DR, Gerisch G, Titus MA.

Curr Biol. 2001 Mar 6;11(5):318-29.


Unconventional myosins: anchors in the membrane traffic relay.

Tuxworth RI, Titus MA.

Traffic. 2000 Jan;1(1):11-8. Review.


Dictyostelium RasG is required for normal motility and cytokinesis, but not growth.

Tuxworth RI, Cheetham JL, Machesky LM, Spiegelmann GB, Weeks G, Insall RH.

J Cell Biol. 1997 Aug 11;138(3):605-14.


DNA polymorphisms of the complement C6 and C7 genes.

Fernie BA, Würzner R, Unsworth DJ, Tuxworth RI, Hobart MJ.

Ann Hum Genet. 1995 Apr;59(2):163-81. Erratum in: Ann Hum Genet 1995 Jul;59(Pt 3):337.


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