Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 206

1.

Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury.

Rosenzweig ES, Salegio EA, Liang JJ, Weber JL, Weinholtz CA, Brock JH, Moseanko R, Hawbecker S, Pender R, Cruzen CL, Iaci JF, Caggiano AO, Blight AR, Haenzi B, Huie JR, Havton LA, Nout-Lomas YS, Fawcett JW, Ferguson AR, Beattie MS, Bresnahan JC, Tuszynski MH.

Nat Neurosci. 2019 Aug;22(8):1269-1275. doi: 10.1038/s41593-019-0424-1. Epub 2019 Jun 24.

PMID:
31235933
2.

Reorganization of Recurrent Layer 5 Corticospinal Networks Following Adult Motor Training.

Biane JS, Takashima Y, Scanziani M, Conner JM, Tuszynski MH.

J Neurosci. 2019 Jun 12;39(24):4684-4693. doi: 10.1523/JNEUROSCI.3442-17.2019. Epub 2019 Apr 4.

PMID:
30948479
3.

Regenerating Corticospinal Axons Innervate Phenotypically Appropriate Neurons within Neural Stem Cell Grafts.

Kumamaru H, Lu P, Rosenzweig ES, Kadoya K, Tuszynski MH.

Cell Rep. 2019 Feb 26;26(9):2329-2339.e4. doi: 10.1016/j.celrep.2019.01.099.

4.

Astrocytes migrate from human neural stem cell grafts and functionally integrate into the injured rat spinal cord.

Lien BV, Tuszynski MH, Lu P.

Exp Neurol. 2019 Apr;314:46-57. doi: 10.1016/j.expneurol.2019.01.006. Epub 2019 Jan 15.

PMID:
30653967
5.

Biomimetic 3D-printed scaffolds for spinal cord injury repair.

Koffler J, Zhu W, Qu X, Platoshyn O, Dulin JN, Brock J, Graham L, Lu P, Sakamoto J, Marsala M, Chen S, Tuszynski MH.

Nat Med. 2019 Feb;25(2):263-269. doi: 10.1038/s41591-018-0296-z. Epub 2019 Jan 14.

6.

Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion.

Castle MJ, Cheng Y, Asokan A, Tuszynski MH.

Sci Adv. 2018 Nov 14;4(11):eaau9859. doi: 10.1126/sciadv.aau9859. eCollection 2018 Nov.

7.

Activation of Intrinsic Growth State Enhances Host Axonal Regeneration into Neural Progenitor Cell Grafts.

Kumamaru H, Lu P, Rosenzweig ES, Tuszynski MH.

Stem Cell Reports. 2018 Oct 9;11(4):861-868. doi: 10.1016/j.stemcr.2018.08.009. Epub 2018 Sep 6.

8.

Generation and post-injury integration of human spinal cord neural stem cells.

Kumamaru H, Kadoya K, Adler AF, Takashima Y, Graham L, Coppola G, Tuszynski MH.

Nat Methods. 2018 Sep;15(9):723-731. doi: 10.1038/s41592-018-0074-3. Epub 2018 Aug 6.

PMID:
30082899
9.

Adult rat myelin enhances axonal outgrowth from neural stem cells.

Poplawski GHD, Lie R, Hunt M, Kumamaru H, Kawaguchi R, Lu P, Schäfer MKE, Woodruff G, Robinson J, Canete P, Dulin JN, Geoffroy CG, Menzel L, Zheng B, Coppola G, Tuszynski MH.

Sci Transl Med. 2018 May 23;10(442). pii: eaal2563. doi: 10.1126/scitranslmed.aal2563.

PMID:
29794059
10.

Adeno-Associated Viral Vector (Serotype 2)-Nerve Growth Factor for Patients With Alzheimer Disease: A Randomized Clinical Trial.

Rafii MS, Tuszynski MH, Thomas RG, Barba D, Brewer JB, Rissman RA, Siffert J, Aisen PS; AAV2-NGF Study Team.

JAMA Neurol. 2018 Jul 1;75(7):834-841. doi: 10.1001/jamaneurol.2018.0233.

11.

MR-guided delivery of AAV2-BDNF into the entorhinal cortex of non-human primates.

Nagahara AH, Wilson BR, Ivasyk I, Kovacs I, Rawalji S, Bringas JR, Pivirotto PJ, Sebastian WS, Samaranch L, Bankiewicz KS, Tuszynski MH.

Gene Ther. 2018 Apr;25(2):104-114. doi: 10.1038/s41434-018-0010-2. Epub 2018 Mar 13.

12.

Restorative effects of human neural stem cell grafts on the primate spinal cord.

Rosenzweig ES, Brock JH, Lu P, Kumamaru H, Salegio EA, Kadoya K, Weber JL, Liang JJ, Moseanko R, Hawbecker S, Huie JR, Havton LA, Nout-Lomas YS, Ferguson AR, Beattie MS, Bresnahan JC, Tuszynski MH.

Nat Med. 2018 May;24(4):484-490. doi: 10.1038/nm.4502. Epub 2018 Feb 26.

13.

Microstructure and in vivo characterization of multi-channel nerve guidance scaffolds.

Pawelec KM, Koffler J, Shahriari D, Galvan A, Tuszynski MH, Sakamoto J.

Biomed Mater. 2018 Apr 25;13(4):044104. doi: 10.1088/1748-605X/aaad85.

PMID:
29411711
14.

Oriented Nanofibrous Polymer Scaffolds Containing Protein-Loaded Porous Silicon Generated by Spray Nebulization.

Zuidema JM, Kumeria T, Kim D, Kang J, Wang J, Hollett G, Zhang X, Roberts DS, Chan N, Dowling C, Blanco-Suarez E, Allen NJ, Tuszynski MH, Sailor MJ.

Adv Mater. 2018 Mar;30(12):e1706785. doi: 10.1002/adma.201706785. Epub 2018 Jan 24.

15.

Injured adult motor and sensory axons regenerate into appropriate organotypic domains of neural progenitor grafts.

Dulin JN, Adler AF, Kumamaru H, Poplawski GHD, Lee-Kubli C, Strobl H, Gibbs D, Kadoya K, Fawcett JW, Lu P, Tuszynski MH.

Nat Commun. 2018 Jan 8;9(1):84. doi: 10.1038/s41467-017-02613-x.

16.

Rodent Neural Progenitor Cells Support Functional Recovery after Cervical Spinal Cord Contusion.

Brock JH, Graham L, Staufenberg E, Im S, Tuszynski MH.

J Neurotrauma. 2018 May 1;35(9):1069-1078. doi: 10.1089/neu.2017.5244. Epub 2018 Mar 1.

17.

Enhanced axonal transport: A novel form of "plasticity" after primate and rodent spinal cord injury.

Brock JH, Rosenzweig ES, Yang H, Tuszynski MH.

Exp Neurol. 2018 Mar;301(Pt A):59-69. doi: 10.1016/j.expneurol.2017.12.009. Epub 2017 Dec 22.

PMID:
29277625
18.

Prolonged human neural stem cell maturation supports recovery in injured rodent CNS.

Lu P, Ceto S, Wang Y, Graham L, Wu D, Kumamaru H, Staufenberg E, Tuszynski MH.

J Clin Invest. 2017 Sep 1;127(9):3287-3299. doi: 10.1172/JCI92955. Epub 2017 Aug 21.

19.

Peripheral nerve growth within a hydrogel microchannel scaffold supported by a kink-resistant conduit.

Shahriari D, Shibayama M, Lynam DA, Wolf KJ, Kubota G, Koffler JY, Tuszynski MH, Campana WM, Sakamoto JS.

J Biomed Mater Res A. 2017 Dec;105(12):3392-3399. doi: 10.1002/jbm.a.36186. Epub 2017 Sep 25.

20.

Myelination of axons emerging from neural progenitor grafts after spinal cord injury.

Hunt M, Lu P, Tuszynski MH.

Exp Neurol. 2017 Oct;296:69-73. doi: 10.1016/j.expneurol.2017.07.005. Epub 2017 Jul 8.

PMID:
28698030
21.

Comprehensive Monosynaptic Rabies Virus Mapping of Host Connectivity with Neural Progenitor Grafts after Spinal Cord Injury.

Adler AF, Lee-Kubli C, Kumamaru H, Kadoya K, Tuszynski MH.

Stem Cell Reports. 2017 Jun 6;8(6):1525-1533. doi: 10.1016/j.stemcr.2017.04.004. Epub 2017 May 4.

22.

Introduction to neuroscience letters special issue: "Plasticity and regeneration after spinal cord injury".

Lu P, Tuszynski MH.

Neurosci Lett. 2017 Jun 23;652:1-2. doi: 10.1016/j.neulet.2017.04.029. Epub 2017 Apr 18. No abstract available.

PMID:
28432027
23.

Hierarchically Ordered Porous and High-Volume Polycaprolactone Microchannel Scaffolds Enhanced Axon Growth in Transected Spinal Cords.

Shahriari D, Koffler JY, Tuszynski MH, Campana WM, Sakamoto JS.

Tissue Eng Part A. 2017 May;23(9-10):415-425. doi: 10.1089/ten.TEA.2016.0378. Epub 2017 Mar 31.

24.

Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration.

Kadoya K, Lu P, Nguyen K, Lee-Kubli C, Kumamaru H, Yao L, Knackert J, Poplawski G, Dulin JN, Strobl H, Takashima Y, Biane J, Conner J, Zhang SC, Tuszynski MH.

Nat Med. 2016 May;22(5):479-87. doi: 10.1038/nm.4066. Epub 2016 Mar 28.

25.

Thalamocortical Projections onto Behaviorally Relevant Neurons Exhibit Plasticity during Adult Motor Learning.

Biane JS, Takashima Y, Scanziani M, Conner JM, Tuszynski MH.

Neuron. 2016 Mar 16;89(6):1173-1179. doi: 10.1016/j.neuron.2016.02.001. Epub 2016 Mar 3.

26.

Rehabilitation drives enhancement of neuronal structure in functionally relevant neuronal subsets.

Wang L, Conner JM, Nagahara AH, Tuszynski MH.

Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):2750-5. doi: 10.1073/pnas.1514682113. Epub 2016 Feb 22.

27.

Analysis of the behavioral, cellular and molecular characteristics of pain in severe rodent spinal cord injury.

Lee-Kubli CA, Ingves M, Henry KW, Shiao R, Collyer E, Tuszynski MH, Campana WM.

Exp Neurol. 2016 Apr;278:91-104. doi: 10.1016/j.expneurol.2016.01.009. Epub 2016 Jan 22.

PMID:
26808661
28.

A Unilateral Cervical Spinal Cord Contusion Injury Model in Non-Human Primates (Macaca mulatta).

Salegio EA, Bresnahan JC, Sparrey CJ, Camisa W, Fischer J, Leasure J, Buckley J, Nout-Lomas YS, Rosenzweig ES, Moseanko R, Strand S, Hawbecker S, Lemoy MJ, Haefeli J, Ma X, Nielson JL, Edgerton VR, Ferguson AR, Tuszynski MH, Beattie MS.

J Neurotrauma. 2016 Mar 1;33(5):439-59. doi: 10.1089/neu.2015.3956. Epub 2016 Jan 20.

29.

Molecular and Cellular Mechanisms of Axonal Regeneration After Spinal Cord Injury.

van Niekerk EA, Tuszynski MH, Lu P, Dulin JN.

Mol Cell Proteomics. 2016 Feb;15(2):394-408. doi: 10.1074/mcp.R115.053751. Epub 2015 Dec 22. Review.

30.

Characterizing the degradation of alginate hydrogel for use in multilumen scaffolds for spinal cord repair.

Shahriari D, Koffler J, Lynam DA, Tuszynski MH, Sakamoto JS.

J Biomed Mater Res A. 2016 Mar;104(3):611-619. doi: 10.1002/jbm.a.35600. Epub 2015 Nov 12.

31.

Transcriptomic Approaches to Neural Repair.

Dulin JN, Antunes-Martins A, Chandran V, Costigan M, Lerch JK, Willis DE, Tuszynski MH.

J Neurosci. 2015 Oct 14;35(41):13860-7. doi: 10.1523/JNEUROSCI.2599-15.2015. Review.

32.

Bone Marrow Stromal Cell Intraspinal Transplants Fail to Improve Motor Outcomes in a Severe Model of Spinal Cord Injury.

Brock JH, Graham L, Staufenberg E, Collyer E, Koffler J, Tuszynski MH.

J Neurotrauma. 2016 Jun 15;33(12):1103-14. doi: 10.1089/neu.2015.4009. Epub 2015 Nov 13.

33.

Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates.

Friedli L, Rosenzweig ES, Barraud Q, Schubert M, Dominici N, Awai L, Nielson JL, Musienko P, Nout-Lomas Y, Zhong H, Zdunowski S, Roy RR, Strand SC, van den Brand R, Havton LA, Beattie MS, Bresnahan JC, Bézard E, Bloch J, Edgerton VR, Ferguson AR, Curt A, Tuszynski MH, Courtine G.

Sci Transl Med. 2015 Aug 26;7(302):302ra134. doi: 10.1126/scitranslmed.aac5811.

34.

Nerve Growth Factor Gene Therapy: Activation of Neuronal Responses in Alzheimer Disease.

Tuszynski MH, Yang JH, Barba D, U HS, Bakay RA, Pay MM, Masliah E, Conner JM, Kobalka P, Roy S, Nagahara AH.

JAMA Neurol. 2015 Oct;72(10):1139-47. doi: 10.1001/jamaneurol.2015.1807.

35.

Motor cortex maturation is associated with reductions in recurrent connectivity among functional subpopulations and increases in intrinsic excitability.

Biane JS, Scanziani M, Tuszynski MH, Conner JM.

J Neurosci. 2015 Mar 18;35(11):4719-28. doi: 10.1523/JNEUROSCI.2792-14.2015.

36.

Brain derived neurotrophic factor release from layer-by-layer coated agarose nerve guidance scaffolds.

Lynam DA, Shahriari D, Wolf KJ, Angart PA, Koffler J, Tuszynski MH, Chan C, Walton P, Sakamoto J.

Acta Biomater. 2015 May;18:128-31. doi: 10.1016/j.actbio.2015.02.014. Epub 2015 Feb 21.

PMID:
25712385
37.

Cholinergic systems are essential for late-stage maturation and refinement of motor cortical circuits.

Ramanathan DS, Conner JM, Anilkumar AA, Tuszynski MH.

J Neurophysiol. 2015 Mar 1;113(5):1585-97. doi: 10.1152/jn.00408.2014. Epub 2014 Dec 10.

38.

Leveraging biomedical informatics for assessing plasticity and repair in primate spinal cord injury.

Nielson JL, Haefeli J, Salegio EA, Liu AW, Guandique CF, Stück ED, Hawbecker S, Moseanko R, Strand SC, Zdunowski S, Brock JH, Roy RR, Rosenzweig ES, Nout-Lomas YS, Courtine G, Havton LA, Steward O, Reggie Edgerton V, Tuszynski MH, Beattie MS, Bresnahan JC, Ferguson AR.

Brain Res. 2015 Sep 4;1619:124-38. doi: 10.1016/j.brainres.2014.10.048. Epub 2014 Nov 4. Review.

39.

Nerve growth factor is primarily produced by GABAergic neurons of the adult rat cortex.

Biane J, Conner JM, Tuszynski MH.

Front Cell Neurosci. 2014 Aug 7;8:220. doi: 10.3389/fncel.2014.00220. eCollection 2014.

40.

Long-distance axonal growth from human induced pluripotent stem cells after spinal cord injury.

Lu P, Woodruff G, Wang Y, Graham L, Hunt M, Wu D, Boehle E, Ahmad R, Poplawski G, Brock J, Goldstein LS, Tuszynski MH.

Neuron. 2014 Aug 20;83(4):789-96. doi: 10.1016/j.neuron.2014.07.014. Epub 2014 Aug 7.

41.

Neural stem cells in models of spinal cord injury.

Tuszynski MH, Wang Y, Graham L, McHale K, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Lu P.

Exp Neurol. 2014 Nov;261:494-500. doi: 10.1016/j.expneurol.2014.07.011. Epub 2014 Jul 28.

PMID:
25079369
42.

Development of a database for translational spinal cord injury research.

Nielson JL, Guandique CF, Liu AW, Burke DA, Lash AT, Moseanko R, Hawbecker S, Strand SC, Zdunowski S, Irvine KA, Brock JH, Nout-Lomas YS, Gensel JC, Anderson KD, Segal MR, Rosenzweig ES, Magnuson DS, Whittemore SR, McTigue DM, Popovich PG, Rabchevsky AG, Scheff SW, Steward O, Courtine G, Edgerton VR, Tuszynski MH, Beattie MS, Bresnahan JC, Ferguson AR.

J Neurotrauma. 2014 Nov 1;31(21):1789-99. doi: 10.1089/neu.2014.3399. Epub 2014 Jul 31.

43.

Axonal growth and connectivity from neural stem cell grafts in models of spinal cord injury.

Lu P, Kadoya K, Tuszynski MH.

Curr Opin Neurobiol. 2014 Aug;27:103-9. doi: 10.1016/j.conb.2014.03.010. Epub 2014 Apr 5. Review.

PMID:
24709371
44.

Neural stem cell dissemination after grafting to CNS injury sites.

Tuszynski MH, Wang Y, Graham L, Gao M, Wu D, Brock J, Blesch A, Rosenzweig ES, Havton LA, Zheng B, Conner JM, Marsala M, Lu P.

Cell. 2014 Jan 30;156(3):388-9. doi: 10.1016/j.cell.2014.01.016. No abstract available.

45.

Guest editorial: Opportunities in rehabilitation research.

Ommaya AK, Adams KM, Allman RM, Collins EG, Cooper RA, Dixon CE, Fishman PS, Henry JA, Kardon R, Kerns RD, Kupersmith J, Lo A, Macko R, McArdle R, McGlinchey RE, McNeil MR, O'Toole TP, Peckham PH, Tuszynski MH, Waxman SG, Wittenberg GF.

J Rehabil Res Dev. 2013;50(6):vii-xxxii. doi: 10.1682/JRRD.2012.09.0167. No abstract available.

46.

Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice.

Nagahara AH, Mateling M, Kovacs I, Wang L, Eggert S, Rockenstein E, Koo EH, Masliah E, Tuszynski MH.

J Neurosci. 2013 Sep 25;33(39):15596-602. doi: 10.1523/JNEUROSCI.5195-12.2013.

47.

SnoN facilitates axonal regeneration after spinal cord injury.

Do JL, Bonni A, Tuszynski MH.

PLoS One. 2013 Aug 2;8(8):e71906. doi: 10.1371/journal.pone.0071906. Print 2013.

48.

Low-density lipoprotein receptor-related protein 1 (LRP1)-dependent cell signaling promotes axonal regeneration.

Yoon C, Van Niekerk EA, Henry K, Ishikawa T, Orita S, Tuszynski MH, Campana WM.

J Biol Chem. 2013 Sep 13;288(37):26557-68. doi: 10.1074/jbc.M113.478552. Epub 2013 Jul 18.

49.
50.

Templated agarose scaffolds for the support of motor axon regeneration into sites of complete spinal cord transection.

Gao M, Lu P, Bednark B, Lynam D, Conner JM, Sakamoto J, Tuszynski MH.

Biomaterials. 2013 Feb;34(5):1529-36. doi: 10.1016/j.biomaterials.2012.10.070. Epub 2012 Nov 23.

Supplemental Content

Loading ...
Support Center