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Items: 1 to 50 of 302

1.

Contribution of allelic imbalance to colorectal cancer.

Palin K, Pitkänen E, Turunen M, Sahu B, Pihlajamaa P, Kivioja T, Kaasinen E, Välimäki N, Hänninen UA, Cajuso T, Aavikko M, Tuupanen S, Kilpivaara O, van den Berg L, Kondelin J, Tanskanen T, Katainen R, Grau M, Rauanheimo H, Plaketti RM, Taira A, Sulo P, Hartonen T, Dave K, Schmierer B, Botla S, Sokolova M, Vähärautio A, Gladysz K, Ongen H, Dermitzakis E, Bramsen JB, Ørntoft TF, Andersen CL, Ristimäki A, Lepistö A, Renkonen-Sinisalo L, Mecklin JP, Taipale J, Aaltonen LA.

Nat Commun. 2018 Sep 10;9(1):3664. doi: 10.1038/s41467-018-06132-1.

2.

Comprehensive evaluation of coding region point mutations in microsatellite-unstable colorectal cancer.

Kondelin J, Salokas K, Saarinen L, Ovaska K, Rauanheimo H, Plaketti RM, Hamberg J, Liu X, Yadav L, Gylfe AE, Cajuso T, Hänninen UA, Palin K, Ristolainen H, Katainen R, Kaasinen E, Tanskanen T, Aavikko M, Taipale M, Taipale J, Renkonen-Sinisalo L, Lepistö A, Koskensalo S, Böhm J, Mecklin JP, Ongen H, Dermitzakis ET, Kilpivaara O, Vahteristo P, Turunen M, Hautaniemi S, Tuupanen S, Karhu A, Välimäki N, Varjosalo M, Pitkänen E, Aaltonen LA.

EMBO Mol Med. 2018 Sep;10(9). pii: e8552. doi: 10.15252/emmm.201708552.

3.

Occupant satisfaction with indoor environmental quality and health after energy retrofits of multi-family buildings: Results from INSULAtE-project.

Haverinen-Shaughnessy U, Pekkonen M, Leivo V, Prasauskas T, Turunen M, Kiviste M, Aaltonen A, Martuzevicius D.

Int J Hyg Environ Health. 2018 Jul;221(6):921-928. doi: 10.1016/j.ijheh.2018.05.009. Epub 2018 May 30.

PMID:
29859666
4.

Linking multiscale deformation to microstructure in cortical bone using in situ loading, digital image correlation and synchrotron X-ray scattering.

Gustafsson A, Mathavan N, Turunen MJ, Engqvist J, Khayyeri H, Hall SA, Isaksson H.

Acta Biomater. 2018 Mar 15;69:323-331. doi: 10.1016/j.actbio.2018.01.037. Epub 2018 Feb 2.

5.

The compositional and nano-structural basis of fracture healing in healthy and osteoporotic bone.

Mathavan N, Turunen MJ, Guizar-Sicairos M, Bech M, Schaff F, Tägil M, Isaksson H.

Sci Rep. 2018 Jan 25;8(1):1591. doi: 10.1038/s41598-018-19296-z.

6.

Doxycycline modulates VEGF-A expression: Failure of doxycycline-inducible lentivirus shRNA vector to knockdown VEGF-A expression in transgenic mice.

Merentie M, Rissanen R, Lottonen-Raikaslehto L, Huusko J, Gurzeler E, Turunen MP, Holappa L, Mäkinen P, Ylä-Herttuala S.

PLoS One. 2018 Jan 19;13(1):e0190981. doi: 10.1371/journal.pone.0190981. eCollection 2018.

7.

Indoor thermal environment, air exchange rates, and carbon dioxide concentrations before and after energy retro fits in Finnish and Lithuanian multi-family buildings.

Leivo V, Prasauskas T, Du L, Turunen M, Kiviste M, Aaltonen A, Martuzevicius D, Haverinen-Shaughnessy U.

Sci Total Environ. 2018 Apr 15;621:398-406. doi: 10.1016/j.scitotenv.2017.11.227. Epub 2017 Nov 27.

PMID:
29190562
8.

Microbial growth in building material samples and occupants' health in severely moisture-damaged homes.

Järvi K, Hyvärinen A, Täubel M, Karvonen AM, Turunen M, Jalkanen K, Patovirta R, Syrjänen T, Pirinen J, Salonen H, Nevalainen A, Pekkanen J.

Indoor Air. 2018 Mar;28(2):287-297. doi: 10.1111/ina.12440. Epub 2017 Dec 2.

PMID:
29151276
9.

Achilles tendon compositional and structural properties are altered after unloading by botox.

Khayyeri H, Blomgran P, Hammerman M, Turunen MJ, Löwgren A, Guizar-Sicairos M, Aspenberg P, Isaksson H.

Sci Rep. 2017 Oct 12;7(1):13067. doi: 10.1038/s41598-017-13107-7.

10.

CRISPR/Cas9 screening using unique molecular identifiers.

Schmierer B, Botla SK, Zhang J, Turunen M, Kivioja T, Taipale J.

Mol Syst Biol. 2017 Oct 9;13(10):945. doi: 10.15252/msb.20177834.

11.

Effects of tissue fixation and dehydration on tendon collagen nanostructure.

Turunen MJ, Khayyeri H, Guizar-Sicairos M, Isaksson H.

J Struct Biol. 2017 Sep;199(3):209-215. doi: 10.1016/j.jsb.2017.07.009. Epub 2017 Jul 28.

PMID:
28760694
12.

Neutron tomographic imaging of bone-implant interface: Comparison with X-ray tomography.

Isaksson H, Le Cann S, Perdikouri C, Turunen MJ, Kaestner A, Tägil M, Hall SA, Tudisco E.

Bone. 2017 Oct;103:295-301. doi: 10.1016/j.bone.2017.07.022. Epub 2017 Jul 22.

PMID:
28739417
13.

Enhancing Angiogenesis in Mice by VEGF-Targeting Small Activating RNAs.

Turunen TA, Ylä-Herttuala S, Turunen MP.

Adv Exp Med Biol. 2017;983:195-205. doi: 10.1007/978-981-10-4310-9_14.

PMID:
28639201
14.

Somatic MED12 Nonsense Mutation Escapes mRNA Decay and Reveals a Motif Required for Nuclear Entry.

Heikkinen T, Kämpjärvi K, Keskitalo S, von Nandelstadh P, Liu X, Rantanen V, Pitkänen E, Kinnunen M, Kuusanmäki H, Kontro M, Turunen M, Mäkinen N, Taipale J, Heckman C, Lehti K, Mustjoki S, Varjosalo M, Vahteristo P.

Hum Mutat. 2017 Mar;38(3):269-274. doi: 10.1002/humu.23157. Epub 2017 Jan 11.

PMID:
28054750
15.

Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion.

Sokolova M, Turunen M, Mortusewicz O, Kivioja T, Herr P, Vähärautio A, Björklund M, Taipale M, Helleday T, Taipale J.

Cell Cycle. 2017 Jan 17;16(2):189-199. doi: 10.1080/15384101.2016.1261765. Epub 2016 Dec 8.

16.

In Vivo Contrast-Enhanced Cone Beam CT Provides Quantitative Information on Articular Cartilage and Subchondral Bone.

Myller KA, Turunen MJ, Honkanen JT, Väänänen SP, Iivarinen JT, Salo J, Jurvelin JS, Töyräs J.

Ann Biomed Eng. 2017 Mar;45(3):811-818. doi: 10.1007/s10439-016-1730-3. Epub 2016 Sep 19.

PMID:
27646147
17.

Statistical associations between housing quality and health among Finnish households with children - Results from two (repeated) national surveys.

Turunen M, Iso-Markku K, Pekkonen M, Haverinen-Shaughnessy U.

Sci Total Environ. 2017 Jan 1;574:1580-1587. doi: 10.1016/j.scitotenv.2016.08.194. Epub 2016 Sep 7.

PMID:
27614864
18.

Myc requires RhoA/SRF to reprogram glutamine metabolism.

Haikala HM, Marques E, Turunen M, Klefström J.

Small GTPases. 2018 May 4;9(3):274-282. doi: 10.1080/21541248.2016.1224287. Epub 2016 Sep 20.

19.

Selective release of muscle-specific, extracellular microRNAs during myogenic differentiation.

Coenen-Stass AM, Betts CA, Lee YF, Mäger I, Turunen MP, El Andaloussi S, Morgan JE, Wood MJ, Roberts TC.

Hum Mol Genet. 2016 Sep 15;25(18):3960-3974. doi: 10.1093/hmg/ddw237. Epub 2016 Jul 27.

20.

Bone mineral crystal size and organization vary across mature rat bone cortex.

Turunen MJ, Kaspersen JD, Olsson U, Guizar-Sicairos M, Bech M, Schaff F, Tägil M, Jurvelin JS, Isaksson H.

J Struct Biol. 2016 Sep;195(3):337-344. doi: 10.1016/j.jsb.2016.07.005. Epub 2016 Jul 11.

21.

Cationic Contrast Agent Diffusion Differs Between Cartilage and Meniscus.

Honkanen JTJ, Turunen MJ, Freedman JD, Saarakkala S, Grinstaff MW, Ylärinne JH, Jurvelin JS, Töyräs J.

Ann Biomed Eng. 2016 Oct;44(10):2913-2921. doi: 10.1007/s10439-016-1629-z. Epub 2016 Apr 29.

22.

Modeling Associations between Principals' Reported Indoor Environmental Quality and Students' Self-Reported Respiratory Health Outcomes Using GLMM and ZIP Models.

Toyinbo O, Matilainen M, Turunen M, Putus T, Shaughnessy R, Haverinen-Shaughnessy U.

Int J Environ Res Public Health. 2016 Mar 30;13(4):385. doi: 10.3390/ijerph13040385.

23.

Small-Angle X-ray Scattering Demonstrates Similar Nanostructure in Cortical Bone from Young Adult Animals of Different Species.

Kaspersen JD, Turunen MJ, Mathavan N, Lages S, Pedersen JS, Olsson U, Isaksson H.

Calcif Tissue Int. 2016 Jul;99(1):76-87. doi: 10.1007/s00223-016-0120-z. Epub 2016 Feb 25.

PMID:
26914607
24.

Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication.

Balistreri G, Viiliäinen J, Turunen M, Diaz R, Lyly L, Pekkonen P, Rantala J, Ojala K, Sarek G, Teesalu M, Denisova O, Peltonen K, Julkunen I, Varjosalo M, Kainov D, Kallioniemi O, Laiho M, Taipale J, Hautaniemi S, Ojala PM.

PLoS Pathog. 2016 Feb 18;12(2):e1005424. doi: 10.1371/journal.ppat.1005424. eCollection 2016 Feb.

25.

Transport of Iodine Is Different in Cartilage and Meniscus.

Honkanen JT, Turunen MJ, Tiitu V, Jurvelin JS, Töyräs J.

Ann Biomed Eng. 2016 Jul;44(7):2114-22. doi: 10.1007/s10439-015-1513-2. Epub 2015 Dec 9.

PMID:
26661617
26.

Identifying User Interaction Patterns in E-Textbooks.

Saarinen S, Heimonen T, Turunen M, Mikkilä-Erdmann M, Raisamo R, Erdmann N, Yrjänäinen S, Keskinen T.

ScientificWorldJournal. 2015;2015:981520. doi: 10.1155/2015/981520. Epub 2015 Oct 29.

27.

Somatic MED12 mutations in prostate cancer and uterine leiomyomas promote tumorigenesis through distinct mechanisms.

Kämpjärvi K, Kim NH, Keskitalo S, Clark AD, von Nandelstadh P, Turunen M, Heikkinen T, Park MJ, Mäkinen N, Kivinummi K, Lintula S, Hotakainen K, Nevanlinna H, Hokland P, Böhling T, Bützow R, Böhm J, Mecklin JP, Järvinen H, Kontro M, Visakorpi T, Taipale J, Varjosalo M, Boyer TG, Vahteristo P.

Prostate. 2016 Jan;76(1):22-31. doi: 10.1002/pros.23092. Epub 2015 Sep 18.

PMID:
26383637
28.

Seasonal and inter-annual variation in the chlorophyll content of three co-existing Sphagnum species exceeds the effect of solar UV reduction in a subarctic peatland.

Hyyryläinen A, Rautio P, Turunen M, Huttunen S.

Springerplus. 2015 Sep 4;4:478. doi: 10.1186/s40064-015-1253-7. eCollection 2015.

29.

Mechanical Analysis of Ultrasound-Activated Pins and Resorbable Screws: Two Different Techniques to Fixate Osteosynthesis in Craniosynostosis Surgery.

Savolainen MJ, Ritvanen AG, Koljonen VS, Turunen MP, Hulkkonen HH, Vuorinen VH, Leikola JP.

J Craniofac Surg. 2015 Jun;26(4):1234-7. doi: 10.1097/SCS.0000000000001736.

PMID:
26080164
30.

Intravenous dexketoprofen induces less injection pain than racemic ketoprofen.

Sjövall S, Kokki M, Nokela A, Halinen L, Turunen M, Kokki H.

J Clin Pharm Ther. 2015 Aug;40(4):431-5. doi: 10.1111/jcpt.12284. Epub 2015 May 22.

PMID:
26011787
31.

Quantitative evaluation of knee subchondral bone mineral density using cone beam computed tomography.

Turunen MJ, Töyräs J, Kokkonen HT, Jurvelin JS.

IEEE Trans Med Imaging. 2015 Oct;34(10):2186-90. doi: 10.1109/TMI.2015.2426684. Epub 2015 Apr 28.

PMID:
25935027
32.

Characterising bone material composition and structure in the ovariectomized (OVX) rat model of osteoporosis.

Mathavan N, Turunen MJ, Tägil M, Isaksson H.

Calcif Tissue Int. 2015 Aug;97(2):134-44. doi: 10.1007/s00223-015-9991-7. Epub 2015 Apr 17.

PMID:
25894067
33.

Sámi reindeer herders' perspective on herbivory of subarctic mountain birch forests by geometrid moths and reindeer: a case study from northernmost Finland.

Vuojala-Magga T, Turunen MT.

Springerplus. 2015 Mar 20;4:134. doi: 10.1186/s40064-015-0921-y. eCollection 2015.

34.

Assessment of indoor environmental quality in existing multi-family buildings in North-East Europe.

Du L, Prasauskas T, Leivo V, Turunen M, Pekkonen M, Kiviste M, Aaltonen A, Martuzevicius D, Haverinen-Shaughnessy U.

Environ Int. 2015 Jun;79:74-84. doi: 10.1016/j.envint.2015.03.001. Epub 2015 Mar 20.

PMID:
25797585
35.

Relationships between tissue composition and viscoelastic properties in human trabecular bone.

Ojanen X, Isaksson H, Töyräs J, Turunen MJ, Malo MK, Halvari A, Jurvelin JS.

J Biomech. 2015 Jan 21;48(2):269-75. doi: 10.1016/j.jbiomech.2014.11.034. Epub 2014 Dec 3.

PMID:
25498367
36.

A New Gene Therapy Approach for Cardiovascular Disease by Non-coding RNAs Acting in the Nucleus.

Husso T, Ylä-Herttuala S, Turunen MP.

Mol Ther Nucleic Acids. 2014 Nov 18;3:e197. doi: 10.1038/mtna.2014.48. Review.

37.

The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera.

Ahola V, Lehtonen R, Somervuo P, Salmela L, Koskinen P, Rastas P, Välimäki N, Paulin L, Kvist J, Wahlberg N, Tanskanen J, Hornett EA, Ferguson LC, Luo S, Cao Z, de Jong MA, Duplouy A, Smolander OP, Vogel H, McCoy RC, Qian K, Chong WS, Zhang Q, Ahmad F, Haukka JK, Joshi A, Salojärvi J, Wheat CW, Grosse-Wilde E, Hughes D, Katainen R, Pitkänen E, Ylinen J, Waterhouse RM, Turunen M, Vähärautio A, Ojanen SP, Schulman AH, Taipale M, Lawson D, Ukkonen E, Mäkinen V, Goldsmith MR, Holm L, Auvinen P, Frilander MJ, Hanski I.

Nat Commun. 2014 Sep 5;5:4737. doi: 10.1038/ncomms5737.

38.

Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.

Turunen M, Spaeth JM, Keskitalo S, Park MJ, Kivioja T, Clark AD, Mäkinen N, Gao F, Palin K, Nurkkala H, Vähärautio A, Aavikko M, Kämpjärvi K, Vahteristo P, Kim CA, Aaltonen LA, Varjosalo M, Taipale J, Boyer TG.

Cell Rep. 2014 May 8;7(3):654-60. doi: 10.1016/j.celrep.2014.03.047. Epub 2014 Apr 18.

39.

Indoor environmental quality in school buildings, and the health and wellbeing of students.

Turunen M, Toyinbo O, Putus T, Nevalainen A, Shaughnessy R, Haverinen-Shaughnessy U.

Int J Hyg Environ Health. 2014 Sep;217(7):733-9. doi: 10.1016/j.ijheh.2014.03.002. Epub 2014 Mar 19.

PMID:
24709335
40.

Epigenetic upregulation of endogenous VEGF-A reduces myocardial infarct size in mice.

Turunen MP, Husso T, Musthafa H, Laidinen S, Dragneva G, Laham-Karam N, Honkanen S, Paakinaho A, Laakkonen JP, Gao E, Vihinen-Ranta M, Liimatainen T, Ylä-Herttuala S.

PLoS One. 2014 Feb 26;9(2):e89979. doi: 10.1371/journal.pone.0089979. eCollection 2014.

41.

Evaluation of composition and mineral structure of callus tissue in rat femoral fracture.

Turunen MJ, Lages S, Labrador A, Olsson U, Tägil M, Jurvelin JS, Isaksson H.

J Biomed Opt. 2014 Feb;19(2):025003. doi: 10.1117/1.JBO.19.2.025003.

PMID:
24522802
42.

Increased heterogeneity of bone matrix mineralization in pediatric patients prone to fractures: a biopsy study.

Tamminen IS, Misof BM, Roschger P, Mäyränpää MK, Turunen MJ, Isaksson H, Kröger H, Mäkitie O, Klaushofer K.

J Bone Miner Res. 2014;29(5):1110-7. doi: 10.1002/jbmr.2124.

43.

Epigenetic regulation in vascular cells.

Turunen MP, Aavik E, Ylä-Herttuala S.

Curr Opin Lipidol. 2013 Oct;24(5):438-43. doi: 10.1097/MOL.0b013e328364292d. Review.

PMID:
23872638
44.

Identification of candidate oncogenes in human colorectal cancers with microsatellite instability.

Gylfe AE, Kondelin J, Turunen M, Ristolainen H, Katainen R, Pitkänen E, Kaasinen E, Rantanen V, Tanskanen T, Varjosalo M, Lehtonen H, Palin K, Taipale M, Taipale J, Renkonen-Sinisalo L, Järvinen H, Böhm J, Mecklin JP, Ristimäki A, Kilpivaara O, Tuupanen S, Karhu A, Vahteristo P, Aaltonen LA.

Gastroenterology. 2013 Sep;145(3):540-3.e22. doi: 10.1053/j.gastro.2013.05.015. Epub 2013 May 16.

PMID:
23684749
45.

Incidence and bone biopsy findings of atypical femoral fractures.

Tamminen IS, Yli-Kyyny T, Isaksson H, Turunen MJ, Tong X, Jurvelin JS, Kröger H.

J Bone Miner Metab. 2013 Sep;31(5):585-94. doi: 10.1007/s00774-013-0448-7. Epub 2013 Apr 4.

PMID:
23553501
46.

Efficient pro-survival/angiogenic miRNA delivery by an MRI-detectable nanomaterial.

Gomes RS, das Neves RP, Cochlin L, Lima A, Carvalho R, Korpisalo P, Dragneva G, Turunen M, Liimatainen T, Clarke K, Ylä-Herttuala S, Carr C, Ferreira L.

ACS Nano. 2013 Apr 23;7(4):3362-72. doi: 10.1021/nn400171w. Epub 2013 Mar 8.

PMID:
23451983
47.

Composition and microarchitecture of human trabecular bone change with age and differ between anatomical locations.

Turunen MJ, Prantner V, Jurvelin JS, Kröger H, Isaksson H.

Bone. 2013 May;54(1):118-25. doi: 10.1016/j.bone.2013.01.045. Epub 2013 Feb 4.

PMID:
23388419
48.

Transcriptional networks controlling the cell cycle.

Bonke M, Turunen M, Sokolova M, Vähärautio A, Kivioja T, Taipale M, Björklund M, Taipale J.

G3 (Bethesda). 2013 Jan;3(1):75-90. doi: 10.1534/g3.112.004283. Epub 2013 Jan 1.

49.

Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors.

Sur IK, Hallikas O, Vähärautio A, Yan J, Turunen M, Enge M, Taipale M, Karhu A, Aaltonen LA, Taipale J.

Science. 2012 Dec 7;338(6112):1360-3. doi: 10.1126/science.1228606. Epub 2012 Nov 1.

50.

Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis.

Nikulenkov F, Spinnler C, Li H, Tonelli C, Shi Y, Turunen M, Kivioja T, Ignatiev I, Kel A, Taipale J, Selivanova G.

Cell Death Differ. 2012 Dec;19(12):1992-2002. doi: 10.1038/cdd.2012.89. Epub 2012 Jul 13.

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