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Items: 1 to 50 of 512

1.

Differential regulation of claudin-2 and claudin-15 expression in children and adults with malabsorptive disease.

Ong MLDM, Yeruva S, Sailer A, Nilsen SP, Turner JR.

Lab Invest. 2019 Oct 11. doi: 10.1038/s41374-019-0324-8. [Epub ahead of print]

PMID:
31605016
2.

Altered gating of Kv1.4 in the nucleus accumbens suppresses motivation for reward.

O'Donovan B, Adeluyi A, Anderson EL, Cole RD, Turner JR, Ortinski PI.

Elife. 2019 Sep 5;8. pii: e47870. doi: 10.7554/eLife.47870.

3.

The International Council for Harmonisation and a Case Study in Regulatory Science.

Turner JR.

Ther Innov Regul Sci. 2019 Sep;53(5):561-563. doi: 10.1177/2168479019869740. No abstract available.

PMID:
31438726
4.

Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase 3 Expression.

Kuo WT, Shen L, Zuo L, Shashikanth N, Ong MLDM, Wu L, Zha J, Edelblum KL, Wang Y, Wang Y, Nilsen SP, Turner JR.

Gastroenterology. 2019 Aug 8. pii: S0016-5085(19)41200-6. doi: 10.1053/j.gastro.2019.07.058. [Epub ahead of print]

PMID:
31401143
5.

Restricted mean survival time for the analysis of cardiovascular outcome trials assessing non-inferiority: Case studies from antihyperglycemic drug development.

Manner DH, Battioui C, Hantel S, Beasley BN, Wei LJ, Geiger MJ, Turner JR, Abt M.

Am Heart J. 2019 Sep;215:178-186. doi: 10.1016/j.ahj.2019.05.016. Epub 2019 Jun 6. Review.

PMID:
31349109
6.

Slowed gastric emptying and improved oral glucose tolerance produced by a nanomolar-potency inhibitor of calcium-activated chloride channel TMEM16A.

Cil O, Anderson MO, Yen R, Kelleher B, Huynh TL, Seo Y, Nilsen SP, Turner JR, Verkman AS.

FASEB J. 2019 Oct;33(10):11247-11257. doi: 10.1096/fj.201900858R. Epub 2019 Jul 12.

PMID:
31299174
7.

Molecular Mechanisms Associated with Nicotine Pharmacology and Dependence.

Fowler CD, Turner JR, Imad Damaj M.

Handb Exp Pharmacol. 2019 Jul 3. doi: 10.1007/164_2019_252. [Epub ahead of print]

PMID:
31267166
8.

Correction to: Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens.

Pandey SP, Yan J, Turner JR, Abraham C.

Mucosal Immunol. 2019 Jul;12(4):1065. doi: 10.1038/s41385-019-0179-8.

PMID:
31182816
9.

Occludin knockdown is not sufficient to induce transepithelial macromolecule passage.

Richter JF, Hildner M, Schmauder R, Turner JR, Schumann M, Reiche J.

Tissue Barriers. 2019;7(2):1612661. doi: 10.1080/21688370.2019.1608759. Epub 2019 Jun 4.

PMID:
31161924
10.

On the Genesis of CMGH.

Turner JR.

Cell Mol Gastroenterol Hepatol. 2019;8(1):143-144. doi: 10.1016/j.jcmgh.2019.04.011. Epub 2019 May 10. No abstract available.

11.

Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens.

Pandey SP, Yan J, Turner JR, Abraham C.

Mucosal Immunol. 2019 Jul;12(4):874-887. doi: 10.1038/s41385-019-0165-1. Epub 2019 May 3. Erratum in: Mucosal Immunol. 2019 Jun 10;:.

PMID:
31053739
12.

Relative vs absolute risk and odds: Understanding the difference.

Jiroutek MR, Turner JR.

J Clin Hypertens (Greenwich). 2019 Jun;21(6):859-861. doi: 10.1111/jch.13548. Epub 2019 Apr 25. No abstract available.

13.

Rigor, Reproducibility, and Responsibility: A Quantum of Solace.

Turner JR.

Cell Mol Gastroenterol Hepatol. 2019;7(4):869-871. doi: 10.1016/j.jcmgh.2019.03.006. Epub 2019 Apr 9. No abstract available.

14.

Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis.

Graham WV, He W, Marchiando AM, Zha J, Singh G, Li HS, Biswas A, Ong MLDM, Jiang ZH, Choi W, Zuccola H, Wang Y, Griffith J, Wu J, Rosenberg HJ, Wang Y, Snapper SB, Ostrov D, Meredith SC, Miller LW, Turner JR.

Nat Med. 2019 Apr;25(4):690-700. doi: 10.1038/s41591-019-0393-7. Epub 2019 Apr 1.

15.

"We" Before "Me": Differences in Usage of Collectivistic and Individualistic Language Influence Judgments of Electability and Performance.

Turner JR, Stanley JT.

J Gerontol B Psychol Sci Soc Sci. 2019 Mar 10. pii: gbz030. doi: 10.1093/geronb/gbz030. [Epub ahead of print]

PMID:
30852612
16.

The Role of Worst-Case Scenarios in Sponsors' and Regulators' Decision Making.

Turner JR.

Ther Innov Regul Sci. 2019 Jan;53(1):5-7. doi: 10.1177/2168479018822468. No abstract available.

PMID:
30789097
17.

An Age-Friendly University (AFU) assists with technology learning and social engagement among older adults and individuals with developmental disabilities.

Stanley JT, Morrison LB, Webster BA, Turner JR, Richards CJ.

Gerontol Geriatr Educ. 2019 Apr-Jun;40(2):261-275. doi: 10.1080/02701960.2019.1572009. Epub 2019 Feb 1.

PMID:
30707650
18.

Interleukin 22 Expands Transit-Amplifying Cells While Depleting Lgr5+ Stem Cells via Inhibition of Wnt and Notch Signaling.

Zha JM, Li HS, Lin Q, Kuo WT, Jiang ZH, Tsai PY, Ding N, Wu J, Xu SF, Wang YT, Pan J, Zhou XM, Chen K, Tao M, Odenwald MA, Tamura A, Tsukita S, Turner JR, He WQ.

Cell Mol Gastroenterol Hepatol. 2019;7(2):255-274. doi: 10.1016/j.jcmgh.2018.09.006. Epub 2018 Sep 18.

19.

Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability.

Nalle SC, Zuo L, Ong MLDM, Singh G, Worthylake AM, Choi W, Manresa MC, Southworth AP, Edelblum KL, Baker GJ, Joseph NE, Savage PA, Turner JR.

J Clin Invest. 2019 Feb 1;129(2):902-914. doi: 10.1172/JCI98554. Epub 2019 Jan 22.

20.

cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity.

Tse CM, Yin J, Singh V, Sarker R, Lin R, Verkman AS, Turner JR, Donowitz M.

Cell Mol Gastroenterol Hepatol. 2019;7(3):641-653. doi: 10.1016/j.jcmgh.2019.01.002. Epub 2019 Jan 17.

21.

Measuring Blood Pressure in Clinical Practice: We Can and Must Do Better.

Turner JR.

Ther Innov Regul Sci. 2018 Nov;52(6):685-686. doi: 10.1177/2168479018809978. No abstract available.

PMID:
30419184
22.

The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations in vitro and in vivo.

Odenwald MA, Choi W, Kuo WT, Singh G, Sailer A, Wang Y, Shen L, Fanning AS, Turner JR.

J Biol Chem. 2018 Nov 9;293(45):17317-17335. doi: 10.1074/jbc.RA118.003908. Epub 2018 Sep 21.

23.

DIA Then and Now: A Half-Century Odyssey.

Turner JR.

Ther Innov Regul Sci. 2017 Sep;51(5):531-533. doi: 10.1177/2168479017725516. No abstract available.

PMID:
30231677
24.

Update From the Field of Renal Sympathetic Denervation: A Focus on Safety Nomenclature Considerations.

Turner JR.

Ther Innov Regul Sci. 2017 Nov;51(6):664-668. doi: 10.1177/2168479017739927. No abstract available.

PMID:
30227095
25.

Proposed Proarrhythmic Cardiac Safety Education in Medical, Pharmacy, and Nursing Schools: An Interprofessional Model.

Turner JR.

Ther Innov Regul Sci. 2018 Sep;52(5):529-530. doi: 10.1177/2168479018797715. No abstract available.

PMID:
30204494
26.

An intestinal paracellular pathway biased toward positively-charged macromolecules.

Almansour K, Taverner A, Turner JR, Eggleston IM, Mrsny RJ.

J Control Release. 2018 Oct 28;288:111-125. doi: 10.1016/j.jconrel.2018.09.003. Epub 2018 Sep 6.

PMID:
30194947
27.

Comprehensive In Vitro Proarrhythmia Assay (CiPA) Update from a Cardiac Safety Research Consortium / Health and Environmental Sciences Institute / FDA Meeting.

Strauss DG, Gintant G, Li Z, Wu W, Blinova K, Vicente J, Turner JR, Sager PT.

Ther Innov Regul Sci. 2019 Jul;53(4):519-525. doi: 10.1177/2168479018795117. Epub 2018 Aug 29.

PMID:
30157676
28.

Cell injury triggers actin polymerization to initiate epithelial restitution.

Aihara E, Medina-Candelaria NM, Hanyu H, Matthis AL, Engevik KA, Gurniak CB, Witke W, Turner JR, Zhang T, Montrose MH.

J Cell Sci. 2018 Aug 20;131(16). pii: jcs216317. doi: 10.1242/jcs.216317.

29.

"Assessment of Pressor Effects of Drugs"-A New US FDA Draft Guidance for Industry.

Turner JR.

Ther Innov Regul Sci. 2018 Jul;52(4):397-399. doi: 10.1177/2168479018786478. No abstract available.

PMID:
29996733
30.

Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection.

Zukauskas A, Mrsny RJ, Cortés Barrantes P, Turner JR, Leong JM, McCormick BA.

mSphere. 2018 Jul 5;3(4). pii: e00303-18. doi: 10.1128/mSphere.00303-18.

31.

Mesenteric Adipose-derived Stromal Cells From Crohn's Disease Patients Induce Protective Effects in Colonic Epithelial Cells and Mice With Colitis.

Hoffman JM, Sideri A, Ruiz JJ, Stavrakis D, Shih DQ, Turner JR, Pothoulakis C, Karagiannides I.

Cell Mol Gastroenterol Hepatol. 2018 Feb 8;6(1):1-16. doi: 10.1016/j.jcmgh.2018.02.001. eCollection 2018.

32.

Epithelial IL-15 Is a Critical Regulator of γδ Intraepithelial Lymphocyte Motility within the Intestinal Mucosa.

Hu MD, Ethridge AD, Lipstein R, Kumar S, Wang Y, Jabri B, Turner JR, Edelblum KL.

J Immunol. 2018 Jul 15;201(2):747-756. doi: 10.4049/jimmunol.1701603. Epub 2018 Jun 8.

33.

Individual-Specific QT Interval Correction for Drugs With Substantial Heart Rate Effect Using Holter ECGs Extracted Over a Wide Range of Heart Rates.

Panicker GK, Kadam P, Chakraborty S, Kothari S, Turner JR, Karnad DR.

J Clin Pharmacol. 2018 May 18. doi: 10.1002/jcph.1258. [Epub ahead of print]

PMID:
29775213
34.

A Milestone: Therapeutic Innovation & Regulatory Science Has Been Accepted for Inclusion in MEDLINE.

Turner JR.

Ther Innov Regul Sci. 2018 May;52(3):265-266. doi: 10.1177/2168479018773321. No abstract available.

PMID:
29723060
35.

Cardiodiabesity and Related Updates.

Turner JR.

Ther Innov Regul Sci. 2018 Jan;52(1):4-6. doi: 10.1177/2168479017747867. No abstract available.

PMID:
29714607
36.

Reporting of Randomized Clinical Trials Remains Far from Optimal.

Turner JR.

Ther Innov Regul Sci. 2018 Mar;52(2):137-139. doi: 10.1177/2168479018761353. No abstract available.

PMID:
29714522
37.

Dopamine Triggers CTCF-Dependent Morphological and Genomic Remodeling of Astrocytes.

Galloway A, Adeluyi A, O'Donovan B, Fisher ML, Rao CN, Critchfield P, Sajish M, Turner JR, Ortinski PI.

J Neurosci. 2018 May 23;38(21):4846-4858. doi: 10.1523/JNEUROSCI.3349-17.2018. Epub 2018 Apr 30.

38.

Limited impact of an invasive oyster on intertidal assemblage structure and biodiversity: the importance of environmental context and functional equivalency with native species.

Zwerschke N, Hollyman PR, Wild R, Strigner R, Turner JR, King JW.

Mar Biol. 2018;165(5):89. doi: 10.1007/s00227-018-3338-7. Epub 2018 Apr 20.

39.

State of the Journal: CMGH's Progress, Prospects, and Impact Factor.

Turner JR, Goldenring JR, Rescigno M, Wells RG.

Cell Mol Gastroenterol Hepatol. 2017 Dec 18;5(2):157-158. doi: 10.1016/j.jcmgh.2017.12.002. eCollection 2018. No abstract available.

40.

Attaching-and-Effacing Pathogens Exploit Junction Regulatory Activities of N-WASP and SNX9 to Disrupt the Intestinal Barrier.

Garber JJ, Mallick EM, Scanlon KM, Turner JR, Donnenberg MS, Leong JM, Snapper SB.

Cell Mol Gastroenterol Hepatol. 2017 Dec 15;5(3):273-288. doi: 10.1016/j.jcmgh.2017.11.015. eCollection 2018 Mar.

41.

Drug-induced Proarrhythmia and Torsade de Pointes: A Primer for Students and Practitioners of Medicine and Pharmacy.

Turner JR, Rodriguez I, Mantovani E, Gintant G, Kowey PR, Klotzbaugh RJ, Prasad K, Sager PT, Stockbridge N, Strnadova C; Cardiac Safety Research Consortium.

J Clin Pharmacol. 2018 Apr 19. doi: 10.1002/jcph.1129. [Epub ahead of print] Review.

PMID:
29672845
42.

Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation.

Drolia R, Tenguria S, Durkes AC, Turner JR, Bhunia AK.

Cell Host Microbe. 2018 Apr 11;23(4):470-484.e7. doi: 10.1016/j.chom.2018.03.004. Epub 2018 Apr 5.

43.

Lactobacillus accelerates ISCs regeneration to protect the integrity of intestinal mucosa through activation of STAT3 signaling pathway induced by LPLs secretion of IL-22.

Hou Q, Ye L, Liu H, Huang L, Yang Q, Turner JR, Yu Q.

Cell Death Differ. 2018 Sep;25(9):1657-1670. doi: 10.1038/s41418-018-0070-2. Epub 2018 Feb 19.

44.

State of the Journal: CMGH's Progress, Prospects, and Impact Factor.

Turner JR, Goldenring JR, Rescigno M, Wells RG.

Gastroenterology. 2018 Feb;154(3):460-461. doi: 10.1053/j.gastro.2018.01.008. No abstract available.

PMID:
29433893
45.

An Essential Postdevelopmental Role for Lis1 in Mice.

Hines TJ, Gao X, Sahu S, Lange MM, Turner JR, Twiss JL, Smith DS.

eNeuro. 2018 Feb 2;5(1). pii: ENEURO.0350-17.2018. doi: 10.1523/ENEURO.0350-17.2018. eCollection 2018 Jan-Feb.

46.

An algorithm for the classification of mRNA patterns in eosinophilic esophagitis: Integration of machine learning.

Sallis BF, Erkert L, Moñino-Romero S, Acar U, Wu R, Konnikova L, Lexmond WS, Hamilton MJ, Dunn WA, Szepfalusi Z, Vanderhoof JA, Snapper SB, Turner JR, Goldsmith JD, Spencer LA, Nurko S, Fiebiger E.

J Allergy Clin Immunol. 2018 Apr;141(4):1354-1364.e9. doi: 10.1016/j.jaci.2017.11.027. Epub 2017 Dec 19.

47.

Enabling social listening for cardiac safety monitoring: Proceedings from a drug information association-cardiac safety research consortium cosponsored think tank.

Seifert HA, Malik RE, Bhattacharya M, Campbell KR, Okun S, Pierce C, Terkowitz J, Turner JR, Krucoff MW, Powell GE.

Am Heart J. 2017 Dec;194:107-115. doi: 10.1016/j.ahj.2017.08.021. Epub 2017 Sep 4. Review.

PMID:
29223428
48.

Why it is nonsensical to use retrospective power analyses to conduct a postmortem on your study.

Jiroutek MR, Turner JR.

J Clin Hypertens (Greenwich). 2018 Feb;20(2):408-410. doi: 10.1111/jch.13173. Epub 2017 Nov 23. No abstract available.

49.

Neuregulin 3 Signaling Mediates Nicotine-Dependent Synaptic Plasticity in the Orbitofrontal Cortex and Cognition.

Zhou L, Fisher ML, Cole RD, Gould TJ, Parikh V, Ortinski PI, Turner JR.

Neuropsychopharmacology. 2018 May;43(6):1343-1354. doi: 10.1038/npp.2017.278. Epub 2017 Nov 7.

50.

Health assessment of future PM2.5 exposures from indoor, outdoor, and secondhand tobacco smoke concentrations under alternative policy pathways in Ulaanbaatar, Mongolia.

Hill LD, Edwards R, Turner JR, Argo YD, Olkhanud PB, Odsuren M, Guttikunda S, Ochir C, Smith KR.

PLoS One. 2017 Oct 31;12(10):e0186834. doi: 10.1371/journal.pone.0186834. eCollection 2017. Erratum in: PLoS One. 2017 Dec 22;12 (12 ):e0190432.

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