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Items: 1 to 50 of 525

1.

Cumulative Histologic Inflammation Predicts Colorectal Neoplasia in Ulcerative Colitis: A Validation Study.

Yvellez OV, Rai V, Sossenheimer PH, Hart J, Turner JR, Weber C, El Jurdi K, Rubin DT.

Inflamm Bowel Dis. 2020 Mar 10. pii: izaa047. doi: 10.1093/ibd/izaa047. [Epub ahead of print]

PMID:
32152624
2.

Targeted Intestinal Tight Junction Hyperpermeability Alters the Microbiome, Behavior, and Visceromotor Responses.

Inczefi O, Bacquié V, Olier-Pierre M, Rincel M, Ringot-Destrez B, Ellero-Simatos S, Eutamène H, Bétoulières C, Thomas J, Laine J, Gros L, Lévêque M, Leonard R, Harkat C, Robbe-Masselot C, Roka R, Mercier-Bonin M, Theodorou V, Darnaudéry M, Turner JR, Ferrier L.

Cell Mol Gastroenterol Hepatol. 2020 Mar 6. pii: S2352-345X(20)30035-7. doi: 10.1016/j.jcmgh.2020.02.008. [Epub ahead of print] No abstract available.

3.

Quantification of Proliferative and Dead Cells in Enteroids.

Li HS, Xu SF, Sheng JY, Jiang ZH, Wang J, Ding N, Wang T, Odenwald MA, Turner JR, He WQ, Xu H, Zha JM.

J Vis Exp. 2020 Jan 31;(155). doi: 10.3791/60501.

PMID:
32065148
4.

Cadmium ingestion exacerbates Salmonella infection, with a loss of goblet cells through activation of Notch signaling pathways by ROS in the intestine.

Xie S, Jiang L, Wang M, Sun W, Yu S, Turner JR, Yu Q.

J Hazard Mater. 2020 Feb 9;391:122262. doi: 10.1016/j.jhazmat.2020.122262. [Epub ahead of print]

PMID:
32062544
5.

Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis.

He WQ, Wang J, Sheng JY, Zha JM, Graham WV, Turner JR.

Int J Mol Sci. 2020 Feb 3;21(3). pii: E993. doi: 10.3390/ijms21030993. Review.

6.

Drug-induced proarrhythmia: Discussion and considerations for clinical practice.

Klotzbaugh RJ, Martin A, Turner JR.

J Am Assoc Nurse Pract. 2020 Feb;32(2):128-135. doi: 10.1097/JXX.0000000000000348.

PMID:
32015278
7.

Age similarities in matching pro- and contra-hedonic emotional strategies to everyday scenarios.

Allard ES, Stanley JT, Turner JR, Harrington AK.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2020 Feb 3:1-23. doi: 10.1080/13825585.2020.1722792. [Epub ahead of print]

PMID:
32011217
8.

Drug-induced proarrhythmia: Discussion and considerations for clinical practice.

Klotzbaugh RJ, Martin A, Turner JR.

JAAPA. 2020 Feb;33(2):1-7. doi: 10.1097/01.JAA.0000651776.53223.e7.

PMID:
31990841
9.

Histologic Healing Is More Strongly Associated with Clinical Outcomes in Ileal Crohn's Disease than Endoscopic Healing.

Christensen B, Erlich J, Gibson PR, Turner JR, Hart J, Rubin DT.

Clin Gastroenterol Hepatol. 2019 Dec 5. pii: S1542-3565(19)31396-5. doi: 10.1016/j.cgh.2019.11.056. [Epub ahead of print]

PMID:
31812654
10.

Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation.

Aksenova M, Sybrandt J, Cui B, Sikirzhytski V, Ji H, Odhiambo D, Lucius MD, Turner JR, Broude E, Peña E, Lizarraga S, Zhu J, Safro I, Wyatt MD, Shtutman M.

J Neuroimmune Pharmacol. 2019 Dec 4. doi: 10.1007/s11481-019-09885-8. [Epub ahead of print]

PMID:
31802418
11.

How to Prescribe Drugs With an Identified Proarrhythmic Liability.

Thind M, Rodriguez I, Kosari S, Turner JR.

J Clin Pharmacol. 2020 Mar;60(3):284-294. doi: 10.1002/jcph.1551. Epub 2019 Nov 19.

PMID:
31743455
12.

Identification of Risk of QT Prolongation by Pharmacists When Conducting Medication Reviews in Residential Aged Care Settings: A Missed Opportunity?

Christensen L, Turner JR, Peterson GM, Naunton M, Thomas J, Yee KC, Kosari S.

J Clin Med. 2019 Nov 4;8(11). pii: E1866. doi: 10.3390/jcm8111866.

13.

Microglia morphology and proinflammatory signaling in the nucleus accumbens during nicotine withdrawal.

Adeluyi A, Guerin L, Fisher ML, Galloway A, Cole RD, Chan SSL, Wyatt MD, Davis SW, Freeman LR, Ortinski PI, Turner JR.

Sci Adv. 2019 Oct 9;5(10):eaax7031. doi: 10.1126/sciadv.aax7031. eCollection 2019 Oct.

14.

Differential regulation of claudin-2 and claudin-15 expression in children and adults with malabsorptive disease.

Ong MLDM, Yeruva S, Sailer A, Nilsen SP, Turner JR.

Lab Invest. 2020 Mar;100(3):483-490. doi: 10.1038/s41374-019-0324-8. Epub 2019 Oct 11.

PMID:
31605016
15.

Altered gating of Kv1.4 in the nucleus accumbens suppresses motivation for reward.

O'Donovan B, Adeluyi A, Anderson EL, Cole RD, Turner JR, Ortinski PI.

Elife. 2019 Sep 5;8. pii: e47870. doi: 10.7554/eLife.47870.

16.

The International Council for Harmonisation and a Case Study in Regulatory Science.

Turner JR.

Ther Innov Regul Sci. 2019 Sep;53(5):561-563. doi: 10.1177/2168479019869740. No abstract available.

PMID:
31438726
17.

Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase-3 Expression.

Kuo WT, Shen L, Zuo L, Shashikanth N, Ong MLDM, Wu L, Zha J, Edelblum KL, Wang Y, Wang Y, Nilsen SP, Turner JR.

Gastroenterology. 2019 Nov;157(5):1323-1337. doi: 10.1053/j.gastro.2019.07.058. Epub 2019 Aug 8.

PMID:
31401143
18.

Restricted mean survival time for the analysis of cardiovascular outcome trials assessing non-inferiority: Case studies from antihyperglycemic drug development.

Manner DH, Battioui C, Hantel S, Beasley BN, Wei LJ, Geiger MJ, Turner JR, Abt M.

Am Heart J. 2019 Sep;215:178-186. doi: 10.1016/j.ahj.2019.05.016. Epub 2019 Jun 6. Review.

PMID:
31349109
19.

Slowed gastric emptying and improved oral glucose tolerance produced by a nanomolar-potency inhibitor of calcium-activated chloride channel TMEM16A.

Cil O, Anderson MO, Yen R, Kelleher B, Huynh TL, Seo Y, Nilsen SP, Turner JR, Verkman AS.

FASEB J. 2019 Oct;33(10):11247-11257. doi: 10.1096/fj.201900858R. Epub 2019 Jul 12.

PMID:
31299174
20.

Molecular Mechanisms Associated with Nicotine Pharmacology and Dependence.

Fowler CD, Turner JR, Imad Damaj M.

Handb Exp Pharmacol. 2019 Jul 3. doi: 10.1007/164_2019_252. [Epub ahead of print]

PMID:
31267166
21.

Correction to: Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens.

Pandey SP, Yan J, Turner JR, Abraham C.

Mucosal Immunol. 2019 Jul;12(4):1065. doi: 10.1038/s41385-019-0179-8.

PMID:
31182816
22.

Occludin knockdown is not sufficient to induce transepithelial macromolecule passage.

Richter JF, Hildner M, Schmauder R, Turner JR, Schumann M, Reiche J.

Tissue Barriers. 2019;7(2):1612661. doi: 10.1080/21688370.2019.1608759. Epub 2019 Jun 4.

PMID:
31161924
23.

On the Genesis of CMGH.

Turner JR.

Cell Mol Gastroenterol Hepatol. 2019;8(1):143-144. doi: 10.1016/j.jcmgh.2019.04.011. Epub 2019 May 10. No abstract available.

24.

Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens.

Pandey SP, Yan J, Turner JR, Abraham C.

Mucosal Immunol. 2019 Jul;12(4):874-887. doi: 10.1038/s41385-019-0165-1. Epub 2019 May 3. Erratum in: Mucosal Immunol. 2019 Jun 10;:.

25.

Relative vs absolute risk and odds: Understanding the difference.

Jiroutek MR, Turner JR.

J Clin Hypertens (Greenwich). 2019 Jun;21(6):859-861. doi: 10.1111/jch.13548. Epub 2019 Apr 25. No abstract available.

26.

Rigor, Reproducibility, and Responsibility: A Quantum of Solace.

Turner JR.

Cell Mol Gastroenterol Hepatol. 2019;7(4):869-871. doi: 10.1016/j.jcmgh.2019.03.006. Epub 2019 Apr 9. No abstract available.

27.

Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis.

Graham WV, He W, Marchiando AM, Zha J, Singh G, Li HS, Biswas A, Ong MLDM, Jiang ZH, Choi W, Zuccola H, Wang Y, Griffith J, Wu J, Rosenberg HJ, Wang Y, Snapper SB, Ostrov D, Meredith SC, Miller LW, Turner JR.

Nat Med. 2019 Apr;25(4):690-700. doi: 10.1038/s41591-019-0393-7. Epub 2019 Apr 1.

28.

"We" Before "Me": Differences in Usage of Collectivistic and Individualistic Language Influence Judgments of Electability and Performance.

Turner JR, Stanley JT.

J Gerontol B Psychol Sci Soc Sci. 2019 Mar 10. pii: gbz030. doi: 10.1093/geronb/gbz030. [Epub ahead of print]

PMID:
30852612
29.

The Role of Worst-Case Scenarios in Sponsors' and Regulators' Decision Making.

Turner JR.

Ther Innov Regul Sci. 2019 Jan;53(1):5-7. doi: 10.1177/2168479018822468. No abstract available.

PMID:
30789097
30.

An Age-Friendly University (AFU) assists with technology learning and social engagement among older adults and individuals with developmental disabilities.

Stanley JT, Morrison LB, Webster BA, Turner JR, Richards CJ.

Gerontol Geriatr Educ. 2019 Apr-Jun;40(2):261-275. doi: 10.1080/02701960.2019.1572009. Epub 2019 Feb 1.

PMID:
30707650
31.

Interleukin 22 Expands Transit-Amplifying Cells While Depleting Lgr5+ Stem Cells via Inhibition of Wnt and Notch Signaling.

Zha JM, Li HS, Lin Q, Kuo WT, Jiang ZH, Tsai PY, Ding N, Wu J, Xu SF, Wang YT, Pan J, Zhou XM, Chen K, Tao M, Odenwald MA, Tamura A, Tsukita S, Turner JR, He WQ.

Cell Mol Gastroenterol Hepatol. 2019;7(2):255-274. doi: 10.1016/j.jcmgh.2018.09.006. Epub 2018 Sep 18.

32.

Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability.

Nalle SC, Zuo L, Ong MLDM, Singh G, Worthylake AM, Choi W, Manresa MC, Southworth AP, Edelblum KL, Baker GJ, Joseph NE, Savage PA, Turner JR.

J Clin Invest. 2019 Feb 1;129(2):902-914. doi: 10.1172/JCI98554. Epub 2019 Jan 22.

33.

cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity.

Tse CM, Yin J, Singh V, Sarker R, Lin R, Verkman AS, Turner JR, Donowitz M.

Cell Mol Gastroenterol Hepatol. 2019;7(3):641-653. doi: 10.1016/j.jcmgh.2019.01.002. Epub 2019 Jan 17.

34.

Measuring Blood Pressure in Clinical Practice: We Can and Must Do Better.

Turner JR.

Ther Innov Regul Sci. 2018 Nov;52(6):685-686. doi: 10.1177/2168479018809978. No abstract available.

PMID:
30419184
35.

The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations in vitro and in vivo.

Odenwald MA, Choi W, Kuo WT, Singh G, Sailer A, Wang Y, Shen L, Fanning AS, Turner JR.

J Biol Chem. 2018 Nov 9;293(45):17317-17335. doi: 10.1074/jbc.RA118.003908. Epub 2018 Sep 21.

36.

DIA Then and Now: A Half-Century Odyssey.

Turner JR.

Ther Innov Regul Sci. 2017 Sep;51(5):531-533. doi: 10.1177/2168479017725516. No abstract available.

PMID:
30231677
37.

Update From the Field of Renal Sympathetic Denervation: A Focus on Safety Nomenclature Considerations.

Turner JR.

Ther Innov Regul Sci. 2017 Nov;51(6):664-668. doi: 10.1177/2168479017739927. No abstract available.

PMID:
30227095
38.

Proposed Proarrhythmic Cardiac Safety Education in Medical, Pharmacy, and Nursing Schools: An Interprofessional Model.

Turner JR.

Ther Innov Regul Sci. 2018 Sep;52(5):529-530. doi: 10.1177/2168479018797715. No abstract available.

PMID:
30204494
39.

An intestinal paracellular pathway biased toward positively-charged macromolecules.

Almansour K, Taverner A, Turner JR, Eggleston IM, Mrsny RJ.

J Control Release. 2018 Oct 28;288:111-125. doi: 10.1016/j.jconrel.2018.09.003. Epub 2018 Sep 6.

40.

Comprehensive In Vitro Proarrhythmia Assay (CiPA) Update from a Cardiac Safety Research Consortium / Health and Environmental Sciences Institute / FDA Meeting.

Strauss DG, Gintant G, Li Z, Wu W, Blinova K, Vicente J, Turner JR, Sager PT.

Ther Innov Regul Sci. 2019 Jul;53(4):519-525. doi: 10.1177/2168479018795117. Epub 2018 Aug 29.

PMID:
30157676
41.

Cell injury triggers actin polymerization to initiate epithelial restitution.

Aihara E, Medina-Candelaria NM, Hanyu H, Matthis AL, Engevik KA, Gurniak CB, Witke W, Turner JR, Zhang T, Montrose MH.

J Cell Sci. 2018 Aug 20;131(16). pii: jcs216317. doi: 10.1242/jcs.216317.

42.

"Assessment of Pressor Effects of Drugs"-A New US FDA Draft Guidance for Industry.

Turner JR.

Ther Innov Regul Sci. 2018 Jul;52(4):397-399. doi: 10.1177/2168479018786478. No abstract available.

PMID:
29996733
43.

Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection.

Zukauskas A, Mrsny RJ, Cortés Barrantes P, Turner JR, Leong JM, McCormick BA.

mSphere. 2018 Jul 5;3(4). pii: e00303-18. doi: 10.1128/mSphere.00303-18.

44.

Mesenteric Adipose-derived Stromal Cells From Crohn's Disease Patients Induce Protective Effects in Colonic Epithelial Cells and Mice With Colitis.

Hoffman JM, Sideri A, Ruiz JJ, Stavrakis D, Shih DQ, Turner JR, Pothoulakis C, Karagiannides I.

Cell Mol Gastroenterol Hepatol. 2018 Feb 8;6(1):1-16. doi: 10.1016/j.jcmgh.2018.02.001. eCollection 2018.

45.

Epithelial IL-15 Is a Critical Regulator of γδ Intraepithelial Lymphocyte Motility within the Intestinal Mucosa.

Hu MD, Ethridge AD, Lipstein R, Kumar S, Wang Y, Jabri B, Turner JR, Edelblum KL.

J Immunol. 2018 Jul 15;201(2):747-756. doi: 10.4049/jimmunol.1701603. Epub 2018 Jun 8.

46.

Individual-Specific QT Interval Correction for Drugs With Substantial Heart Rate Effect Using Holter ECGs Extracted Over a Wide Range of Heart Rates.

Panicker GK, Kadam P, Chakraborty S, Kothari S, Turner JR, Karnad DR.

J Clin Pharmacol. 2018 May 18. doi: 10.1002/jcph.1258. [Epub ahead of print]

PMID:
29775213
47.

A Milestone: Therapeutic Innovation & Regulatory Science Has Been Accepted for Inclusion in MEDLINE.

Turner JR.

Ther Innov Regul Sci. 2018 May;52(3):265-266. doi: 10.1177/2168479018773321. No abstract available.

PMID:
29723060
48.

Cardiodiabesity and Related Updates.

Turner JR.

Ther Innov Regul Sci. 2018 Jan;52(1):4-6. doi: 10.1177/2168479017747867. No abstract available.

PMID:
29714607
49.

Reporting of Randomized Clinical Trials Remains Far from Optimal.

Turner JR.

Ther Innov Regul Sci. 2018 Mar;52(2):137-139. doi: 10.1177/2168479018761353. No abstract available.

PMID:
29714522
50.

Dopamine Triggers CTCF-Dependent Morphological and Genomic Remodeling of Astrocytes.

Galloway A, Adeluyi A, O'Donovan B, Fisher ML, Rao CN, Critchfield P, Sajish M, Turner JR, Ortinski PI.

J Neurosci. 2018 May 23;38(21):4846-4858. doi: 10.1523/JNEUROSCI.3349-17.2018. Epub 2018 Apr 30.

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