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Should Genetic Testing for Cancer Predisposition Be Standard-of-Care for Women with Invasive Breast Cancer? The Murtha Cancer Center Experience.

Rummel SK, Lovejoy LA, Turner CE, Shriver CD, Ellsworth RE.

Cancers (Basel). 2020 Jan 17;12(1). pii: E234. doi: 10.3390/cancers12010234.


The Emergence of Successful Streptococcus pyogenes Lineages through Convergent Pathways of Capsule Loss and Recombination Directing High Toxin Expression.

Turner CE, Holden MTG, Blane B, Horner C, Peacock SJ, Sriskandan S.

mBio. 2019 Dec 10;10(6). pii: e02521-19. doi: 10.1128/mBio.02521-19.


The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts.

Vohnoutka RB, Gulvady AC, Goreczny G, Alpha K, Handelman SK, Sexton JZ, Turner CE.

Mol Biol Cell. 2019 Dec 1;30(25):3037-3056. doi: 10.1091/mbc.E19-08-0442. Epub 2019 Oct 23.


High burden and seasonal variation of paediatric scabies and pyoderma prevalence in The Gambia: A cross-sectional study.

Armitage EP, Senghore E, Darboe S, Barry M, Camara J, Bah S, Marks M, Cerami C, Roca A, Antonio M, Turner CE, de Silva TI.

PLoS Negl Trop Dis. 2019 Oct 14;13(10):e0007801. doi: 10.1371/journal.pntd.0007801. eCollection 2019 Oct.


Toxic Shock Syndrome Toxin 1 Evaluation and Antibiotic Impact in a Transgenic Model of Staphylococcal Soft Tissue Infection.

Sharma H, Turner CE, Siggins MK, El-Bahrawy M, Pichon B, Kearns A, Sriskandan S.

mSphere. 2019 Oct 9;4(5). pii: e00665-19. doi: 10.1128/mSphere.00665-19.


Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study.

Lynskey NN, Jauneikaite E, Li HK, Zhi X, Turner CE, Mosavie M, Pearson M, Asai M, Lobkowicz L, Chow JY, Parkhill J, Lamagni T, Chalker VJ, Sriskandan S.

Lancet Infect Dis. 2019 Nov;19(11):1209-1218. doi: 10.1016/S1473-3099(19)30446-3. Epub 2019 Sep 10.


Pathogenicity Factors in Group C and G Streptococci.

Turner CE, Bubba L, Efstratiou A.

Microbiol Spectr. 2019 May;7(3). doi: 10.1128/microbiolspec.GPP3-0020-2018. Review.


Paxillin-dependent regulation of apical-basal polarity in mammary gland morphogenesis.

Xu W, Gulvady AC, Goreczny GJ, Olson EC, Turner CE.

Development. 2019 May 1;146(9). pii: dev174367. doi: 10.1242/dev.174367.


Hic-5 regulates Src-induced invadopodia rosette formation and organization.

Gulvady AC, Forsythe IJ, Turner CE.

Mol Biol Cell. 2019 May 15;30(11):1298-1313. doi: 10.1091/mbc.E18-10-0629. Epub 2019 Mar 20.


Streptococcal superantigen-induced expansion of human tonsil T cells leads to altered T follicular helper cell phenotype, B cell death and reduced immunoglobulin release.

Davies FJ, Olme C, Lynskey NN, Turner CE, Sriskandan S.

Clin Exp Immunol. 2019 Jul;197(1):83-94. doi: 10.1111/cei.13282. Epub 2019 Mar 13.


Identification of two new core chromosome-encoded superantigens in Streptococcus pyogenes; speQ and speR.

Reglinski M, Sriskandan S, Turner CE.

J Infect. 2019 May;78(5):358-363. doi: 10.1016/j.jinf.2019.02.005. Epub 2019 Feb 20.


Nuclear position relative to the Golgi body and nuclear orientation are differentially responsive indicators of cell polarized motility.

Brasch ME, Passucci G, Gulvady AC, Turner CE, Manning ML, Henderson JH.

PLoS One. 2019 Feb 13;14(2):e0211408. doi: 10.1371/journal.pone.0211408. eCollection 2019.


Impact of contusion injury on intramuscular emm1 group a streptococcus infection and lymphatic spread.

Lamb LE, Siggins MK, Scudamore C, Macdonald W, Turner CE, Lynskey NN, Tan LKK, Sriskandan S.

Virulence. 2018;9(1):1074-1084. doi: 10.1080/21505594.2018.1482180.


Hic-5 expression is a major indicator of cancer cell morphology, migration, and plasticity in three-dimensional matrices.

Gulvady AC, Dubois F, Deakin NO, Goreczny GJ, Turner CE.

Mol Biol Cell. 2018 Jul 15;29(13):1704-1717. doi: 10.1091/mbc.E18-02-0092. Epub 2018 May 17.


Proteomic analysis at the sites of clinical infection with invasive Streptococcus pyogenes.

Edwards RJ, Pyzio M, Gierula M, Turner CE, Abdul-Salam VB, Sriskandan S.

Sci Rep. 2018 Apr 13;8(1):5950. doi: 10.1038/s41598-018-24216-2.


The DNases of pathogenic Lancefield streptococci.

Remmington A, Turner CE.

Microbiology. 2018 Mar;164(3):242-250. doi: 10.1099/mic.0.000612. Epub 2018 Jan 25. Review.


De novo variants in CDK13 associated with syndromic ID/DD: Molecular and clinical delineation of 15 individuals and a further review.

van den Akker WMR, Brummelman I, Martis LM, Timmermans RN, Pfundt R, Kleefstra T, Willemsen MH, Gerkes EH, Herkert JC, van Essen AJ, Rump P, Vansenne F, Terhal PA, van Haelst MM, Cristian I, Turner CE, Cho MT, Begtrup A, Willaert R, Fassi E, van Gassen KLI, Stegmann APA, de Vries BBA, Schuurs-Hoeijmakers JHM.

Clin Genet. 2018 May;93(5):1000-1007. doi: 10.1111/cge.13225.


Clinical and Molecular Epidemiology of Staphylococcal Toxic Shock Syndrome in the United Kingdom.

Sharma H, Smith D, Turner CE, Game L, Pichon B, Hope R, Hill R, Kearns A, Sriskandan S.

Emerg Infect Dis. 2018 Feb;24(2). doi: 10.3201/eid2402.170606.


Hic-5 regulates fibrillar adhesion formation to control tumor extracellular matrix remodeling through interaction with tensin1.

Goreczny GJ, Forsythe IJ, Turner CE.

Oncogene. 2018 Mar;37(13):1699-1713. doi: 10.1038/s41388-017-0074-2. Epub 2018 Jan 19.


Military genomics: a perspective on the successes and challenges of genomic medicine in the Armed Services.

De Castro MJ, Turner CE.

Mol Genet Genomic Med. 2017 Nov;5(6):617-620. doi: 10.1002/mgg3.335. Epub 2017 Sep 14.


Paxillin regulates cell polarization and anterograde vesicle trafficking during cell migration.

Dubois F, Alpha K, Turner CE.

Mol Biol Cell. 2017 Dec 15;28(26):3815-3831. doi: 10.1091/mbc.E17-08-0488. Epub 2017 Oct 18.


Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation.

Rashid M, Belmont J, Carpenter D, Turner CE, Olson EC.

Development. 2017 Nov 1;144(21):4002-4014. doi: 10.1242/dev.147934. Epub 2017 Sep 21.


Community outbreaks of group A Streptococcus revealed by genome sequencing.

Turner CE, Bedford L, Brown NM, Judge K, Török ME, Parkhill J, Peacock SJ.

Sci Rep. 2017 Aug 17;7(1):8554. doi: 10.1038/s41598-017-08914-x.


On-command on/off switching of progenitor cell and cancer cell polarized motility and aligned morphology via a cytocompatible shape memory polymer scaffold.

Wang J, Quach A, Brasch ME, Turner CE, Henderson JH.

Biomaterials. 2017 Sep;140:150-161. doi: 10.1016/j.biomaterials.2017.06.016. Epub 2017 Jun 14.


Enhanced nasopharyngeal infection and shedding associated with an epidemic lineage of emm3 group A Streptococcus.

Afshar B, Turner CE, Lamagni TL, Smith KC, Al-Shahib A, Underwood A, Holden MTG, Efstratiou A, Sriskandan S.

Virulence. 2017 Oct 3;8(7):1390-1400. doi: 10.1080/21505594.2017.1325070. Epub 2017 May 1.


MicroRNAs of the mir-17~92 cluster regulate multiple aspects of pancreatic tumor development and progression.

Quattrochi B, Gulvady A, Driscoll DR, Sano M, Klimstra DS, Turner CE, Lewis BC.

Oncotarget. 2017 May 30;8(22):35902-35918. doi: 10.18632/oncotarget.16277.


Laparoscopic ventral rectopexy for rectal prolapse and rectal intussusception using a biological mesh.

Albayati S, Morgan MJ, Turner CE.

Colorectal Dis. 2017 Sep;19(9):857-862. doi: 10.1111/codi.13671.


Corrigendum: Emergence of a novel lineage containing a prophage in emm/M3 group A Streptococcus associated with upsurge in invasive disease in the UK.

Al-Shahib A, Underwood A, Afshar B, Turner CE, Lamagni T, Sriskandan S, Efstratiou A.

Microb Genom. 2016 Nov 30;2(11):e000097. doi: 10.1099/mgen.0.000097. eCollection 2016 Nov.


Emergence of a novel lineage containing a prophage in emm/M3 group A Streptococcus associated with upsurge in invasive disease in the UK.

Al-Shahib A, Underwood A, Afshar B, Turner CE, Lamagni T, Sriskandan S, Efstratiou A.

Microb Genom. 2016 Jun 24;2(6):e000059. doi: 10.1099/mgen.0.000059. eCollection 2016 Jun. Erratum in: Microb Genom. 2016 Nov 30;2(11):e000097.


Identification of commonly expressed exoproteins and proteolytic cleavage events by proteomic mining of clinically relevant UK isolates of Staphylococcus aureus.

Smith DS, Siggins MK, Gierula M, Pichon B, Turner CE, Lynskey NN, Mosavie M, Kearns AM, Edwards RJ, Sriskandan S.

Microb Genom. 2016 Feb 23;2(2):e000049. doi: 10.1099/mgen.0.000049. eCollection 2016 Feb.


Paxillin genes and actomyosin contractility regulate myotome morphogenesis in zebrafish.

Jacob AE, Amack JD, Turner CE.

Dev Biol. 2017 May 1;425(1):70-84. doi: 10.1016/j.ydbio.2017.03.012. Epub 2017 Mar 15.


Frequent inactivating germline mutations in DNA repair genes in patients with Ewing sarcoma.

Brohl AS, Patidar R, Turner CE, Wen X, Song YK, Wei JS, Calzone KA, Khan J.

Genet Med. 2017 Aug;19(8):955-958. doi: 10.1038/gim.2016.206. Epub 2017 Jan 26.


EIF2S3 Mutations Associated with Severe X-Linked Intellectual Disability Syndrome MEHMO.

Skopkova M, Hennig F, Shin BS, Turner CE, Stanikova D, Brennerova K, Stanik J, Fischer U, Henden L, Müller U, Steinberger D, Leshinsky-Silver E, Bottani A, Kurdiova T, Ukropec J, Nyitrayova O, Kolnikova M, Klimes I, Borck G, Bahlo M, Haas SA, Kim JR, Lotspeich-Cole LE, Gasperikova D, Dever TE, Kalscheuer VM.

Hum Mutat. 2017 Apr;38(4):409-425. doi: 10.1002/humu.23170. Epub 2017 Jan 23.


Hic-5 remodeling of the stromal matrix promotes breast tumor progression.

Goreczny GJ, Ouderkirk-Pecone JL, Olson EC, Krendel M, Turner CE.

Oncogene. 2017 May 11;36(19):2693-2703. doi: 10.1038/onc.2016.422. Epub 2016 Nov 28.


Evolution and Expression of Paxillin Genes in Teleost Fish.

Jacob AE, Turner CE, Amack JD.

PLoS One. 2016 Nov 2;11(11):e0165266. doi: 10.1371/journal.pone.0165266. eCollection 2016.


De novo missense variants in PPP1CB are associated with intellectual disability and congenital heart disease.

Ma L, Bayram Y, McLaughlin HM, Cho MT, Krokosky A, Turner CE, Lindstrom K, Bupp CP, Mayberry K, Mu W, Bodurtha J, Weinstein V, Zadeh N, Alcaraz W, Powis Z, Shao Y, Scott DA, Lewis AM, White JJ, Jhangiani SN, Gulec EY, Lalani SR, Lupski JR, Retterer K, Schnur RE, Wentzensen IM, Bale S, Chung WK.

Hum Genet. 2016 Dec;135(12):1399-1409. Epub 2016 Sep 28.


Category Membership and Semantic Coding in the Cerebral Hemispheres.

Turner CE, Kellogg RT.

Am J Psychol. 2016 Summer;129(2):135-48.


Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation.

Ouderkirk-Pecone JL, Goreczny GJ, Chase SE, Tatum AH, Turner CE, Krendel M.

Oncotarget. 2016 Jul 19;7(29):46419-46432. doi: 10.18632/oncotarget.10139.


The effect of two levels of hemospermia on stallion fertility.

Turner CE, Walbornn SR, Blanchard TL, Varner DD, Brinsko SP, LaCaze KA, Teague SR, Love CC.

Theriogenology. 2016 Oct 1;86(6):1399-1402. doi: 10.1016/j.theriogenology.2016.04.084. Epub 2016 May 7.


Scarlet Fever Upsurge in England and Molecular-Genetic Analysis in North-West London, 2014.

Turner CE, Pyzio M, Song B, Lamagni T, Meltzer M, Chow JY, Efstratiou A, Curtis S, Sriskandan S.

Emerg Infect Dis. 2016 Jun;22(6):1075-8. doi: 10.3201/eid2206.151726.


Semantic processing in the left versus right cerebral hemispheres following unilateral hand contractions.

Turner CE, Hahn ME, Kellogg RT.

Laterality. 2017 Mar;22(2):219-232. doi: 10.1080/1357650X.2016.1154861. Epub 2016 Mar 7.


Hoyeraal-Hreidarsson Syndrome due to PARN Mutations: Fourteen Years of Follow-Up.

Burris AM, Ballew BJ, Kentosh JB, Turner CE, Norton SA; NCI DCEG Cancer Genomics Research Laboratory; NCI DCEG Cancer Sequencing Working Group, Giri N, Alter BP, Nellan A, Gamper C, Hartman KR, Savage SA.

Pediatr Neurol. 2016 Mar;56:62-68.e1. doi: 10.1016/j.pediatrneurol.2015.12.005. Epub 2015 Dec 19.


Turner et al. Reply to "Emergence of the Same Successful Clade among Distinct Populations of emm89 Streptococcus pyogenes in Multiple Geographic Regions".

Turner CE, Lamagni T, Holden MT, David S, Jones MD, Game L, Efstratiou A, Sriskandan S.

mBio. 2015 Dec 1;6(6):e01883-15. doi: 10.1128/mBio.01883-15. No abstract available.


A Simplified System for Evaluating Cell Mechanosensing and Durotaxis In Vitro.

Goreczny GJ, Wormer DB, Turner CE.

J Vis Exp. 2015 Aug 27;(102):e52949. doi: 10.3791/52949.


Emergence of a New Highly Successful Acapsular Group A Streptococcus Clade of Genotype emm89 in the United Kingdom.

Turner CE, Abbott J, Lamagni T, Holden MT, David S, Jones MD, Game L, Efstratiou A, Sriskandan S.

mBio. 2015 Jul 14;6(4):e00622. doi: 10.1128/mBio.00622-15.


Comparative quantification of dietary supplemented neural creatine concentrations with (1)H-MRS peak fitting and basis spectrum methods.

Turner CE, Russell BR, Gant N.

Magn Reson Imaging. 2015 Nov;33(9):1163-1167. doi: 10.1016/j.mri.2015.06.018. Epub 2015 Jun 25.


Hypogammaglobulinemia and impaired antibody response in a child with chromosome 2p15-16.1 microdeletion syndrome.

Ottolini KM, Turner CE, Gada SM.

Ann Allergy Asthma Immunol. 2015 Aug;115(2):153-5. doi: 10.1016/j.anai.2015.05.016. Epub 2015 Jun 20. No abstract available.


Panton-Valentine leucocidin expression by Staphylococcus aureus exposed to common antibiotics.

Turner CE, Sriskandan S.

J Infect. 2015 Sep;71(3):338-46. doi: 10.1016/j.jinf.2015.05.008. Epub 2015 May 28.


A truncation in the regulator RocA underlies heightened capsule expression in serotype M3 group A streptococci.

Lynskey NN, Turner CE, Heng LS, Sriskandan S.

Infect Immun. 2015 Apr;83(4):1732-3. doi: 10.1128/IAI.02892-14. No abstract available.

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