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Items: 1 to 50 of 249

1.

A novel cardiac output response to stress test developed to improve diagnosis and monitoring of heart failure in primary care.

Charman SJ, Okwose NC, Stefanetti RJ, Bailey K, Skinner J, Ristic A, Seferovic PM, Scott M, Turley S, Fuat A, Mant J, Hobbs RFD, MacGowan GA, Jakovljevic DG.

ESC Heart Fail. 2018 Jun 26. doi: 10.1002/ehf2.12302. [Epub ahead of print]

PMID:
29943902
2.

Niemann-Pick C1-deficient mice lacking sterol O-acyltransferase 2 have less hepatic cholesterol entrapment and improved liver function.

Lopez AM, Jones RD, Repa JJ, Turley SD.

Am J Physiol Gastrointest Liver Physiol. 2018 Jun 7. doi: 10.1152/ajpgi.00124.2018. [Epub ahead of print]

PMID:
29878847
3.

Testosterone is an endogenous regulator of BAFF and splenic B cell number.

Wilhelmson AS, Lantero Rodriguez M, Stubelius A, Fogelstrand P, Johansson I, Buechler MB, Lianoglou S, Kapoor VN, Johansson ME, Fagman JB, Duhlin A, Tripathi P, Camponeschi A, Porse BT, Rolink AG, Nissbrandt H, Turley SJ, Carlsten H, Mårtensson IL, Karlsson MCI, Tivesten Å.

Nat Commun. 2018 May 25;9(1):2067. doi: 10.1038/s41467-018-04408-0.

4.

Tumor elastography and its association with collagen and the tumor microenvironment.

Riegler J, Labyed Y, Rosenzweig S, Javinal V, Castiglioni A, Dominguez CX, Long JE, Li Q, Sandoval W, Junttila MR, Turley SJ, Schartner JM, Carano R.

Clin Cancer Res. 2018 May 24. pii: clincanres.3262.2017. doi: 10.1158/1078-0432.CCR-17-3262. [Epub ahead of print]

PMID:
29798909
5.

Identification of Correlative Shifts in Indices of Brain Cholesterol Metabolism in the C57BL6/Mecp2tm1.1Bird Mouse, a Model for Rett Syndrome.

Lütjohann D, Lopez AM, Chuang JC, Kerksiek A, Turley SD.

Lipids. 2018 Apr;53(4):363-373. doi: 10.1002/lipd.12041. Epub 2018 May 17.

PMID:
29770459
6.

The crystal structure of the drug target Mycobacterium tuberculosis methionyl-tRNA synthetase in complex with a catalytic intermediate.

Barros-Álvarez X, Turley S, Ranade RM, Gillespie JR, Duster NA, Verlinde CLMJ, Fan E, Buckner FS, Hol WGJ.

Acta Crystallogr F Struct Biol Commun. 2018 Apr 1;74(Pt 4):245-254. doi: 10.1107/S2053230X18003151. Epub 2018 Mar 28.

PMID:
29633973
7.

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel EE III, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Banchereau R, Yang Y, Guan Y, Chalouni C, Ziai J, Şenbabaoğlu Y, Santoro S, Sheinson D, Hung J, Giltnane JM, Pierce AA, Mesh K, Lianoglou S, Riegler J, Carano RAD, Eriksson P, Höglund M, Somarriba L, Halligan DL, van der Heijden MS, Loriot Y, Rosenberg JE, Fong L, Mellman I, Chen DS, Green M, Derleth C, Fine GD, Hegde PS, Bourgon R, Powles T.

Nature. 2018 Feb 22;554(7693):544-548. doi: 10.1038/nature25501. Epub 2018 Feb 14.

PMID:
29443960
8.

Tumour lymph vessels boost immunotherapy.

Moussion C, Turley SJ.

Nature. 2017 Dec 21;552(7685):340-342. doi: 10.1038/d41586-017-08669-5. No abstract available. Erratum in: Nature. 2018 Jan 11;553(7687):164.

PMID:
29293219
9.

Impact of loss of SOAT2 function on disease progression in the lysosomal acid lipase-deficient mouse.

Lopez AM, Chuang JC, Turley SD.

Steroids. 2018 Feb;130:7-14. doi: 10.1016/j.steroids.2017.11.015. Epub 2017 Dec 13.

PMID:
29246491
10.

A short field guide to fibroblast function in immunity.

Buechler MB, Turley SJ.

Semin Immunol. 2018 Feb;35:48-58. doi: 10.1016/j.smim.2017.11.001. Epub 2017 Dec 1. Review.

PMID:
29198601
11.

Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.

Barros-Álvarez X, Kerchner KM, Koh CY, Turley S, Pardon E, Steyaert J, Ranade RM, Gillespie JR, Zhang Z, Verlinde CLMJ, Fan E, Buckner FS, Hol WGJ.

Biochimie. 2017 Jul;138:124-136. doi: 10.1016/j.biochi.2017.04.006. Epub 2017 Apr 18.

12.

Quantitation of the rates of hepatic and intestinal cholesterol synthesis in lysosomal acid lipase-deficient mice before and during treatment with ezetimibe.

Chuang JC, Lopez AM, Turley SD.

Biochem Pharmacol. 2017 Jul 1;135:116-125. doi: 10.1016/j.bcp.2017.03.010. Epub 2017 Mar 18.

13.

Macrophage Death following Influenza Vaccination Initiates the Inflammatory Response that Promotes Dendritic Cell Function in the Draining Lymph Node.

Chatziandreou N, Farsakoglu Y, Palomino-Segura M, D'Antuono R, Pizzagalli DU, Sallusto F, Lukacs-Kornek V, Uguccioni M, Corti D, Turley SJ, Lanzavecchia A, Carroll MC, Gonzalez SF.

Cell Rep. 2017 Mar 7;18(10):2427-2440. doi: 10.1016/j.celrep.2017.02.026.

14.

Measurement of Rates of Cholesterol and Fatty Acid Synthesis In Vivo Using Tritiated Water.

Lopez AM, Chuang JC, Turley SD.

Methods Mol Biol. 2017;1583:241-256. doi: 10.1007/978-1-4939-6875-6_18.

PMID:
28205179
15.

Enteral Administration of Twice-Daily Dolutegravir and Rilpivirine as a Part of a Triple-Therapy Regimen in a Critically Ill Patient with HIV.

Turley SL, Fulco PP.

J Int Assoc Provid AIDS Care. 2017 Mar/Apr;16(2):117-119. doi: 10.1177/2325957417692678. Epub 2017 Feb 15.

PMID:
28198203
16.

'Corrigenda to "Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis" [Brain Res. 1654 (2017) 77-84]'.

Lopez AM, Chuang JC, Posey KS, Turley SD.

Brain Res. 2017 Feb 15;1657:383. doi: 10.1016/j.brainres.2016.12.016. Epub 2016 Dec 22. No abstract available.

17.

Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis.

Lopez AM, Chuang JC, Posey KS, Turley SD.

Brain Res. 2017 Jan 1;1654(Pt A):77-84. doi: 10.1016/j.brainres.2016.10.021. Epub 2016 Oct 24. Erratum in: Brain Res. 2017 Feb 15;1657:383.

18.

Emerging role of ivabradine for rate control in atrial fibrillation.

Turley SL, Francis KE, Lowe DK, Cahoon WD Jr.

Ther Adv Cardiovasc Dis. 2016 Dec;10(6):348-352. Epub 2016 Sep 22. Review.

19.

Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality.

Novkovic M, Onder L, Cupovic J, Abe J, Bomze D, Cremasco V, Scandella E, Stein JV, Bocharov G, Turley SJ, Ludewig B.

PLoS Biol. 2016 Jul 14;14(7):e1002515. doi: 10.1371/journal.pbio.1002515. eCollection 2016 Jul.

20.

Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation.

Pikor NB, Astarita JL, Summers-Deluca L, Galicia G, Qu J, Ward LA, Armstrong S, Dominguez CX, Malhotra D, Heiden B, Kay R, Castanov V, Touil H, Boon L, O'Connor P, Bar-Or A, Prat A, Ramaglia V, Ludwin S, Turley SJ, Gommerman JL.

Immunity. 2015 Dec 15;43(6):1160-73. doi: 10.1016/j.immuni.2015.11.010.

21.

Immunological hallmarks of stromal cells in the tumour microenvironment.

Turley SJ, Cremasco V, Astarita JL.

Nat Rev Immunol. 2015 Nov;15(11):669-82. doi: 10.1038/nri3902. Epub 2015 Oct 16. Review.

PMID:
26471778
22.

Lysosomal Acid Lipase Activity: A Tool for the Detection and Management of Fatty Liver Disease?

Ramirez CM, Lopez AM, Turley SD.

EBioMedicine. 2015 Jun 10;2(7):638-9. doi: 10.1016/j.ebiom.2015.06.008. eCollection 2015 Jul. No abstract available.

23.

PRD125, a potent and selective inhibitor of sterol O-acyltransferase 2 markedly reduces hepatic cholesteryl ester accumulation and improves liver function in lysosomal acid lipase-deficient mice.

Lopez AM, Chuang JC, Posey KS, Ohshiro T, Tomoda H, Rudel LL, Turley SD.

J Pharmacol Exp Ther. 2015 Nov;355(2):159-67. doi: 10.1124/jpet.115.227207. Epub 2015 Aug 17.

24.

DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance.

Conde P, Rodriguez M, van der Touw W, Jimenez A, Burns M, Miller J, Brahmachary M, Chen HM, Boros P, Rausell-Palamos F, Yun TJ, Riquelme P, Rastrojo A, Aguado B, Stein-Streilein J, Tanaka M, Zhou L, Zhang J, Lowary TL, Ginhoux F, Park CG, Cheong C, Brody J, Turley SJ, Lira SA, Bronte V, Gordon S, Heeger PS, Merad M, Hutchinson J, Chen SH, Ochando J.

Immunity. 2015 Jun 16;42(6):1143-58. doi: 10.1016/j.immuni.2015.05.009. Epub 2015 Jun 9.

25.

IgE/FcεRI-Mediated Antigen Cross-Presentation by Dendritic Cells Enhances Anti-Tumor Immune Responses.

Platzer B, Elpek KG, Cremasco V, Baker K, Stout MM, Schultz C, Dehlink E, Shade KT, Anthony RM, Blumberg RS, Turley SJ, Fiebiger E.

Cell Rep. 2015 Mar 3. pii: S2211-1247(15)00143-6. doi: 10.1016/j.celrep.2015.02.015. [Epub ahead of print]

26.

Fibroblastic reticular cells: organization and regulation of the T lymphocyte life cycle.

Brown FD, Turley SJ.

J Immunol. 2015 Feb 15;194(4):1389-94. doi: 10.4049/jimmunol.1402520. Review.

27.

Stromal infrastructure of the lymph node and coordination of immunity.

Chang JE, Turley SJ.

Trends Immunol. 2015 Jan;36(1):30-9. doi: 10.1016/j.it.2014.11.003. Epub 2014 Dec 9. Review.

PMID:
25499856
28.

Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.

Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, Weigert O, Kopp N, Wu SC, Kim SS, Liu H, Tivey T, Christie AL, Elpek KG, Card J, Gritsman K, Gotlib J, Deininger MW, Makishima H, Turley SJ, Javidi-Sharifi N, Maciejewski JP, Jaiswal S, Ebert BL, Rodig SJ, Tyner JW, Marto JA, Weinstock DM, Lane AA.

Nat Med. 2015 Jan;21(1):71-5. doi: 10.1038/nm.3751. Epub 2014 Dec 8.

29.

Hepatic immune regulation by stromal cells.

Schildberg FA, Sharpe AH, Turley SJ.

Curr Opin Immunol. 2015 Feb;32:1-6. doi: 10.1016/j.coi.2014.10.002. Epub 2014 Oct 28. Review.

PMID:
25463592
30.
31.

Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice.

Jones RD, Lopez AM, Tong EY, Posey KS, Chuang JC, Repa JJ, Turley SD.

Steroids. 2015 Jan;93:87-95. doi: 10.1016/j.steroids.2014.11.002. Epub 2014 Nov 28.

32.

The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.

Astarita JL, Cremasco V, Fu J, Darnell MC, Peck JR, Nieves-Bonilla JM, Song K, Kondo Y, Woodruff MC, Gogineni A, Onder L, Ludewig B, Weimer RM, Carroll MC, Mooney DJ, Xia L, Turley SJ.

Nat Immunol. 2015 Jan;16(1):75-84. doi: 10.1038/ni.3035. Epub 2014 Oct 27.

33.

Dendritic cells control fibroblastic reticular network tension and lymph node expansion.

Acton SE, Farrugia AJ, Astarita JL, Mourão-Sá D, Jenkins RP, Nye E, Hooper S, van Blijswijk J, Rogers NC, Snelgrove KJ, Rosewell I, Moita LF, Stamp G, Turley SJ, Sahai E, Reis e Sousa C.

Nature. 2014 Oct 23;514(7523):498-502. doi: 10.1038/nature13814.

34.

B cell homeostasis and follicle confines are governed by fibroblastic reticular cells.

Cremasco V, Woodruff MC, Onder L, Cupovic J, Nieves-Bonilla JM, Schildberg FA, Chang J, Cremasco F, Harvey CJ, Wucherpfennig K, Ludewig B, Carroll MC, Turley SJ.

Nat Immunol. 2014 Oct;15(10):973-81. doi: 10.1038/ni.2965. Epub 2014 Aug 24.

35.

Hepatic entrapment of esterified cholesterol drives continual expansion of whole body sterol pool in lysosomal acid lipase-deficient mice.

Aqul A, Lopez AM, Posey KS, Taylor AM, Repa JJ, Burns DK, Turley SD.

Am J Physiol Gastrointest Liver Physiol. 2014 Oct 15;307(8):G836-47. doi: 10.1152/ajpgi.00243.2014. Epub 2014 Aug 21.

36.

Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in high-mortality murine sepsis.

Fletcher AL, Elman JS, Astarita J, Murray R, Saeidi N, D'Rozario J, Knoblich K, Brown FD, Schildberg FA, Nieves JM, Heng TS, Boyd RL, Turley SJ, Parekkadan B.

Sci Transl Med. 2014 Aug 13;6(249):249ra109. doi: 10.1126/scitranslmed.3009377.

37.

Systemic administration of 2-hydroxypropyl-β-cyclodextrin to symptomatic Npc1-deficient mice slows cholesterol sequestration in the major organs and improves liver function.

Lopez AM, Terpack SJ, Posey KS, Liu B, Ramirez CM, Turley SD.

Clin Exp Pharmacol Physiol. 2014 Oct;41(10):780-7. doi: 10.1111/1440-1681.12285.

38.

Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine.

Woodruff MC, Heesters BA, Herndon CN, Groom JR, Thomas PG, Luster AD, Turley SJ, Carroll MC.

J Exp Med. 2014 Jul 28;211(8):1611-21. doi: 10.1084/jem.20132327. Epub 2014 Jul 21.

39.

Chemokine 'grooming' by cLECs directs DC migration.

Woodruff MC, Turley SJ.

Nat Immunol. 2014 Jul;15(7):595-6. doi: 10.1038/ni.2926. No abstract available.

PMID:
24940945
40.

Safety of total dose iron dextran infusion in geriatric patients with chronic kidney disease and iron deficiency anemia.

Dossabhoy NR, Turley S, Gascoyne R, Tapolyai M, Sulaiman K.

Ren Fail. 2014 Aug;36(7):1033-7. doi: 10.3109/0886022X.2014.918785. Epub 2014 May 21.

PMID:
24845687
41.

The tumor microenvironment shapes lineage, transcriptional, and functional diversity of infiltrating myeloid cells.

Elpek KG, Cremasco V, Shen H, Harvey CJ, Wucherpfennig KW, Goldstein DR, Monach PA, Turley SJ.

Cancer Immunol Res. 2014 Jul;2(7):655-67. doi: 10.1158/2326-6066.CIR-13-0209. Epub 2014 Mar 31.

42.

Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1.

Mundy DI, Lopez AM, Posey KS, Chuang JC, Ramirez CM, Scherer PE, Turley SD.

Biochim Biophys Acta. 2014 Jul;1841(7):995-1002. doi: 10.1016/j.bbalip.2014.04.002. Epub 2014 Apr 18.

43.

Microstructural changes in cartilage and bone related to repetitive overloading in an equine athlete model.

Turley SM, Thambyah A, Riggs CM, Firth EC, Broom ND.

J Anat. 2014 Jun;224(6):647-58. doi: 10.1111/joa.12177. Epub 2014 Apr 1.

44.

Sustained and selective suppression of intestinal cholesterol synthesis by Ro 48-8071, an inhibitor of 2,3-oxidosqualene:lanosterol cyclase, in the BALB/c mouse.

Chuang JC, Valasek MA, Lopez AM, Posey KS, Repa JJ, Turley SD.

Biochem Pharmacol. 2014 Apr 1;88(3):351-63. doi: 10.1016/j.bcp.2014.01.031. Epub 2014 Jan 31.

45.

In vivo discovery of immunotherapy targets in the tumour microenvironment.

Zhou P, Shaffer DR, Alvarez Arias DA, Nakazaki Y, Pos W, Torres AJ, Cremasco V, Dougan SK, Cowley GS, Elpek K, Brogdon J, Lamb J, Turley SJ, Ploegh HL, Root DE, Love JC, Dranoff G, Hacohen N, Cantor H, Wucherpfennig KW.

Nature. 2014 Feb 6;506(7486):52-7. doi: 10.1038/nature12988. Epub 2014 Jan 29.

46.

Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease.

Gylling H, Plat J, Turley S, Ginsberg HN, Ellegård L, Jessup W, Jones PJ, Lütjohann D, Maerz W, Masana L, Silbernagel G, Staels B, Borén J, Catapano AL, De Backer G, Deanfield J, Descamps OS, Kovanen PT, Riccardi G, Tokgözoglu L, Chapman MJ; European Atherosclerosis Society Consensus Panel on Phytosterols.

Atherosclerosis. 2014 Feb;232(2):346-60. doi: 10.1016/j.atherosclerosis.2013.11.043. Epub 2013 Nov 23. Review.

47.

Ezetimibe markedly attenuates hepatic cholesterol accumulation and improves liver function in the lysosomal acid lipase-deficient mouse, a model for cholesteryl ester storage disease.

Chuang JC, Lopez AM, Posey KS, Turley SD.

Biochem Biophys Res Commun. 2014 Jan 17;443(3):1073-7. doi: 10.1016/j.bbrc.2013.12.096. Epub 2013 Dec 25.

48.

Ontogenic changes in lung cholesterol metabolism, lipid content, and histology in mice with Niemann-Pick type C disease.

Ramirez CM, Lopez AM, Le LQ, Posey KS, Weinberg AG, Turley SD.

Biochim Biophys Acta. 2014 Jan;1841(1):54-61. doi: 10.1016/j.bbalip.2013.09.010. Epub 2013 Sep 26.

49.

Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits β-catenin degradation.

Knoblich K, Wang HX, Sharma C, Fletcher AL, Turley SJ, Hemler ME.

Cell Mol Life Sci. 2014 Apr;71(7):1305-14. doi: 10.1007/s00018-013-1444-8. Epub 2013 Aug 18.

PMID:
23955570
50.

Hexamers of the type II secretion ATPase GspE from Vibrio cholerae with increased ATPase activity.

Lu C, Turley S, Marionni ST, Park YJ, Lee KK, Patrick M, Shah R, Sandkvist M, Bush MF, Hol WG.

Structure. 2013 Sep 3;21(9):1707-17. doi: 10.1016/j.str.2013.06.027. Epub 2013 Aug 15.

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