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Items: 1 to 50 of 94

1.

Combined Effects of Three High-Energy Charged Particle Beams Important for Space Flight on Brain, Behavioral and Cognitive Endpoints in B6D2F1 Female and Male Mice.

Raber J, Yamazaki J, Torres ERS, Kirchoff N, Stagaman K, Sharpton T, Turker MS, Kronenberg A.

Front Physiol. 2019 Mar 12;10:179. doi: 10.3389/fphys.2019.00179. eCollection 2019.

2.

Rapid Response and Slow Recovery of the H3K4me3 Epigenomic Marker in the Liver after Light-mediated Phase Advances of the Circadian Clock.

Grygoryev D, Rountree MR, Rwatambuga F, Ohlrich A, Kukino A, Butler MP, Allen CN, Turker MS.

J Biol Rhythms. 2018 Aug;33(4):363-375. doi: 10.1177/0748730418779958. Epub 2018 Jun 11.

PMID:
29888643
3.

Detrimental Effects of Helium Ion Irradiation on Cognitive Performance and Cortical Levels of MAP-2 in B6D2F1 Mice.

Raber J, Torres ERS, Akinyeke T, Lee J, Weber Boutros SJ, Turker MS, Kronenberg A.

Int J Mol Sci. 2018 Apr 20;19(4). pii: E1247. doi: 10.3390/ijms19041247.

4.

Bi-directional and shared epigenomic signatures following proton and 56Fe irradiation.

Impey S, Jopson T, Pelz C, Tafessu A, Fareh F, Zuloaga D, Marzulla T, Riparip LK, Stewart B, Rosi S, Turker MS, Raber J.

Sci Rep. 2017 Aug 31;7(1):10227. doi: 10.1038/s41598-017-09191-4.

5.

Simulated space radiation-induced mutants in the mouse kidney display widespread genomic change.

Turker MS, Grygoryev D, Lasarev M, Ohlrich A, Rwatambuga FA, Johnson S, Dan C, Eckelmann B, Hryciw G, Mao JH, Snijders AM, Gauny S, Kronenberg A.

PLoS One. 2017 Jul 6;12(7):e0180412. doi: 10.1371/journal.pone.0180412. eCollection 2017.

6.

Induction of the long noncoding RNA NBR2 from the bidirectional BRCA1 promoter under hypoxic conditions.

Wiedmeier JE, Ohlrich A, Chu A, Rountree MR, Turker MS.

Mutat Res. 2017 Feb;796:13-19. doi: 10.1016/j.mrfmmm.2017.02.001. Epub 2017 Feb 16.

PMID:
28249151
7.

Short- and long-term effects of 56Fe irradiation on cognition and hippocampal DNA methylation and gene expression.

Impey S, Jopson T, Pelz C, Tafessu A, Fareh F, Zuloaga D, Marzulla T, Riparip LK, Stewart B, Rosi S, Turker MS, Raber J.

BMC Genomics. 2016 Oct 24;17(1):825.

8.

Sex- and dose-dependent effects of calcium ion irradiation on behavioral performance of B6D2F1 mice during contextual fear conditioning training.

Raber J, Weber SJ, Kronenberg A, Turker MS.

Life Sci Space Res (Amst). 2016 Jun;9:56-61. doi: 10.1016/j.lssr.2016.03.002. Epub 2016 Mar 22.

PMID:
27345201
9.

Charged particle mutagenesis at low dose and fluence in mouse splenic T cells.

Grygoryev D, Gauny S, Lasarev M, Ohlrich A, Kronenberg A, Turker MS.

Mutat Res. 2016 Jun;788:32-40. doi: 10.1016/j.mrfmmm.2016.03.004. Epub 2016 Mar 29.

PMID:
27055360
10.

Proton irradiation induces persistent and tissue-specific DNA methylation changes in the left ventricle and hippocampus.

Impey S, Pelz C, Tafessu A, Marzulla T, Turker MS, Raber J.

BMC Genomics. 2016 Mar 31;17:273. doi: 10.1186/s12864-016-2581-x.

11.

Galactic cosmic ray simulation at the NASA Space Radiation Laboratory.

Norbury JW, Schimmerling W, Slaba TC, Azzam EI, Badavi FF, Baiocco G, Benton E, Bindi V, Blakely EA, Blattnig SR, Boothman DA, Borak TB, Britten RA, Curtis S, Dingfelder M, Durante M, Dynan WS, Eisch AJ, Robin Elgart S, Goodhead DT, Guida PM, Heilbronn LH, Hellweg CE, Huff JL, Kronenberg A, La Tessa C, Lowenstein DI, Miller J, Morita T, Narici L, Nelson GA, Norman RB, Ottolenghi A, Patel ZS, Reitz G, Rusek A, Schreurs AS, Scott-Carnell LA, Semones E, Shay JW, Shurshakov VA, Sihver L, Simonsen LC, Story MD, Turker MS, Uchihori Y, Williams J, Zeitlin CJ.

Life Sci Space Res (Amst). 2016 Feb;8:38-51. doi: 10.1016/j.lssr.2016.02.001. Epub 2016 Feb 17.

12.

(16)Oxygen irradiation enhances cued fear memory in B6D2F1 mice.

Raber J, Marzulla T, Kronenberg A, Turker MS.

Life Sci Space Res (Amst). 2015 Nov;7:61-5. doi: 10.1016/j.lssr.2015.10.004. Epub 2015 Oct 22.

PMID:
26553639
13.

Accelerated (48)Ti Ions Induce Autosomal Mutations in Mouse Kidney Epithelium at Low Dose and Fluence.

Hryciw G, Grygoryev D, Lasarev M, Ohlrich A, Dan C, Madhira R, Eckelmann B, Gauny S, Kronenberg A, Turker MS.

Radiat Res. 2015 Oct;184(4):367-77. doi: 10.1667/RR14130.1. Epub 2015 Sep 23.

PMID:
26397174
14.

28Silicon Irradiation Impairs Contextual Fear Memory in B6D2F1 Mice.

Raber J, Marzulla T, Stewart B, Kronenberg A, Turker MS.

Radiat Res. 2015 Jun;183(6):708-12. Epub 2015 May 26.

PMID:
26010712
15.

Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1.

Lu Y, Wajapeyee N, Turker MS, Glazer PM.

Cell Rep. 2014 Jul 24;8(2):501-13. doi: 10.1016/j.celrep.2014.06.035. Epub 2014 Jul 17.

16.

Epigenetic Patents: A Stressful Environment for an Emerging Science.

Noonan W, Dismuke AD, Turker MS.

Biotechnol Law Rep. 2013 Oct;32(5):302-312. No abstract available.

17.

Autosomal mutants of proton-exposed kidney cells display frequent loss of heterozygosity on nonselected chromosomes.

Grygoryev D, Dan C, Gauny S, Eckelmann B, Ohlrich AP, Connolly M, Lasarev M, Grossi G, Kronenberg A, Turker MS.

Radiat Res. 2014 May;181(5):452-63. doi: 10.1667/RR13654.1. Epub 2014 Apr 23.

PMID:
24758577
18.

Comparative analysis of cell killing and autosomal mutation in mouse kidney epithelium exposed to 1 GeV protons in vitro or in vivo.

Kronenberg A, Gauny S, Kwoh E, Grossi G, Dan C, Grygoryev D, Lasarev M, Turker MS.

Radiat Res. 2013 May;179(5):511-20. doi: 10.1667/RR3182.1. Epub 2013 Apr 5.

PMID:
23560634
19.

Autosomal mutations in mouse kidney epithelial cells exposed to high-energy protons in vivo or in culture.

Turker MS, Grygoryev D, Dan C, Eckelmann B, Lasarev M, Gauny S, Kwoh E, Kronenberg A.

Radiat Res. 2013 May;179(5):521-9. doi: 10.1667/RR3174.1. Epub 2013 Apr 5.

PMID:
23560630
20.

Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter.

Lu Y, Chu A, Turker MS, Glazer PM.

Mol Cell Biol. 2011 Aug;31(16):3339-50. doi: 10.1128/MCB.01121-10. Epub 2011 Jun 13.

21.

Marked aneuploidy and loss of multiple chromosomes are common in autosomal mutants isolated from normal mouse kidney epithelium.

Dan C, Grygoryev D, Sandfort K, Connolly M, Cross B, Lasarev M, Kronenberg A, Turker MS.

Genes Chromosomes Cancer. 2011 Apr;50(4):239-49. doi: 10.1002/gcc.20849. Epub 2011 Jan 19.

22.

Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation.

Oyer JA, Yates PA, Godsey S, Turker MS.

Mutat Res. 2011 Jan 10;706(1-2):21-7. doi: 10.1016/j.mrfmmm.2010.10.006. Epub 2010 Oct 28.

23.

In utero life and epigenetic predisposition for disease.

Thornburg KL, Shannon J, Thuillier P, Turker MS.

Adv Genet. 2010;71:57-78. doi: 10.1016/B978-0-12-380864-6.00003-1.

24.

Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors.

Landais I, Hiddingh S, McCarroll M, Yang C, Sun A, Turker MS, Snyder JP, Hoatlin ME.

Mol Cancer. 2009 Dec 31;8:133. doi: 10.1186/1476-4598-8-133.

25.

Comparison of autosomal mutations in mouse kidney epithelial cells exposed to iron ions in situ or in culture.

Turker MS, Connolly L, Dan C, Lasarev M, Gauny S, Kwoh E, Kronenberg A.

Radiat Res. 2009 Nov;172(5):558-66. doi: 10.1667/RR1805.1. Erratum in: Radiat Res. 2010 Jan;173(1):124.

PMID:
19883223
26.

Comparative analysis of cell killing and autosomal mutation in mouse kidney epithelium exposed to 1 GeV/nucleon iron ions in vitro or in situ.

Kronenberg A, Gauny S, Kwoh E, Connolly L, Dan C, Lasarev M, Turker MS.

Radiat Res. 2009 Nov;172(5):550-7. doi: 10.1667/RR1804.1.

PMID:
19883222
27.

Aberrant epigenetic silencing is triggered by a transient reduction in gene expression.

Oyer JA, Chu A, Brar S, Turker MS.

PLoS One. 2009;4(3):e4832. doi: 10.1371/journal.pone.0004832. Epub 2009 Mar 12.

28.

DNA repair modulates the vulnerability of the developing brain to alkylating agents.

Kisby GE, Olivas A, Park T, Churchwell M, Doerge D, Samson LD, Gerson SL, Turker MS.

DNA Repair (Amst). 2009 Mar 1;8(3):400-12. doi: 10.1016/j.dnarep.2008.12.002. Epub 2009 Jan 21.

29.

The frequency of CC to TT tandem mutations in mismatch repair-deficient cells is increased in a cytosine run.

Skinner AM, Dan C, Turker MS.

Mutagenesis. 2008 Mar;23(2):87-91. doi: 10.1093/mutage/gem047. Epub 2008 Jan 4.

PMID:
18178959
30.

High frequency induction of CC to TT tandem mutations in DNA repair-proficient mammalian cells.

Skinner AM, Turker MS.

Photochem Photobiol. 2008 Jan-Feb;84(1):222-7. doi: 10.1111/j.1751-1097.2007.00224.x.

PMID:
18173724
31.

The spectra of large second-step mutations are similar for two different mouse autosomes.

Kasameyer E, Connolly L, Lasarev M, Turker MS.

Mutat Res. 2008 Jan 1;637(1-2):66-72. Epub 2007 Jul 17.

32.

Age-related accumulation of autosomal mutations in solid tissues of the mouse is gender and cell type specific.

Turker MS, Lasarev M, Connolly L, Kasameyer E, Roessler D.

Aging Cell. 2007 Feb;6(1):73-86.

33.

Atm haploinsufficiency does not affect ionizing radiation mutagenesis in solid mouse tissues.

Connolly L, Lasarev M, Jordan R, Schwartz JL, Turker MS.

Radiat Res. 2006 Jul;166(1 Pt 1):39-46.

PMID:
16808618
34.

High frequency induction of mitotic recombination by ionizing radiation in Mlh1 null mouse cells.

Wang Q, Ponomareva ON, Lasarev M, Turker MS.

Mutat Res. 2006 Feb 22;594(1-2):189-98. Epub 2005 Dec 12.

PMID:
16343558
35.

Oxidative mutagenesis, mismatch repair, and aging.

Skinner AM, Turker MS.

Sci Aging Knowledge Environ. 2005 Mar 2;2005(9):re3. Review.

PMID:
15744047
36.

Ionizing radiation induces frequent translocations with delayed replication and condensation.

Breger KS, Smith L, Turker MS, Thayer MJ.

Cancer Res. 2004 Nov 15;64(22):8231-8.

37.

A role for Pms2 in the prevention of tandem CC --> TT substitutions induced by ultraviolet radiation and oxidative stress.

Shin-Darlak CY, Skinner AM, Turker MS.

DNA Repair (Amst). 2005 Jan 2;4(1):51-7.

PMID:
15533837
38.

Persistence of chromatid aberrations in the cells of solid mouse tissues exposed to 137Cs gamma radiation.

Turker MS, Schwartz JL, Jordan R, Ponomareva ON, Connolly L, Kasameyer E, Lasarev M, Clepper L.

Radiat Res. 2004 Oct;162(4):357-64.

PMID:
15447047
39.

Role of nucleotide- and base-excision repair in genotoxin-induced neuronal cell death.

Kisby GE, Lesselroth H, Olivas A, Samson L, Gold B, Tanaka K, Turker MS.

DNA Repair (Amst). 2004 Jun 3;3(6):617-27.

PMID:
15135729
40.

Silencing of mouse Aprt is a gradual process in differentiated cells.

Yates PA, Burman R, Simpson J, Ponomoreva ON, Thayer MJ, Turker MS.

Mol Cell Biol. 2003 Jul;23(13):4461-70.

41.
42.

Autosomal mutation in somatic cells of the mouse.

Turker MS.

Mutagenesis. 2003 Jan;18(1):1-6. Review.

PMID:
12473728
43.

Gene silencing in mammalian cells and the spread of DNA methylation.

Turker MS.

Oncogene. 2002 Aug 12;21(35):5388-93. Review.

44.

A mouse kidney cell line with a G:C --> C:G transversion mutator phenotype.

Shin CY, Ponomareva ON, Connolly L, Turker MS.

Mutat Res. 2002 Jun 19;503(1-2):69-76.

PMID:
12052505
45.
46.
47.

Spontaneously immortalized cell lines obtained from adult Atm null mice retain sensitivity to ionizing radiation and exhibit a mutational pattern suggestive of oxidative stress.

Gage BM, Alroy D, Shin CY, Ponomareva ON, Dhar S, Sharma GG, Pandita TK, Thayer MJ, Turker MS.

Oncogene. 2001 Jul 19;20(32):4291-7.

48.

Somatic cell mutations: can they provide a link between aging and cancer?

Turker MS.

Mech Ageing Dev. 2000 Aug 15;117(1-3):1-19. Review.

PMID:
10958919
49.

Biallelic methylation and silencing of mouse Aprt in normal kidney cells.

Rose JA, Yates PA, Simpson J, Tischfield JA, Stambrook PJ, Turker MS.

Cancer Res. 2000 Jul 1;60(13):3404-8.

50.

Tandem B1 elements located in a mouse methylation center provide a target for de novo DNA methylation.

Yates PA, Burman RW, Mummaneni P, Krussel S, Turker MS.

J Biol Chem. 1999 Dec 17;274(51):36357-61.

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