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Items: 1 to 50 of 170

1.

Correction: Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy.

Springer SU, Chen CH, Rodriguez Pena MDC, Li L, Douville C, Wang Y, Cohen JD, Taheri D, Silliman N, Schaefer J, Ptak J, Dobbyn L, Papoli M, Kinde I, Afsari B, Tregnago AC, Bezerra SM, VandenBussche C, Fujita K, Ertoy D, Cunha IW, Yu L, Bivalacqua TJ, Grollman AP, Diaz LA, Karchin R, Danilova L, Huang CY, Shun CT, Turesky RJ, Yun BH, Rosenquist TA, Pu YS, Hruban RH, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Dickman KG, Netto GJ.

Elife. 2018 Nov 12;7. pii: e43237. doi: 10.7554/eLife.43237.

2.

Targeted and Untargeted Detection of DNA Adducts of Aromatic Amine Carcinogens in Human Bladder by Ultra-Performance Liquid Chromatography-High-Resolution Mass Spectrometry.

Guo J, Villalta PW, Weight CJ, Bonala R, Johnson F, Rosenquist TA, Turesky RJ.

Chem Res Toxicol. 2018 Nov 19. doi: 10.1021/acs.chemrestox.8b00268. [Epub ahead of print]

PMID:
30387604
3.
4.

Biomonitoring an Albumin Adduct of the Cooked Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]pyridine in Humans.

Bellamri M, Wang Y, Yonemori K, White KK, Wilkens LR, Le Marchand L, Turesky RJ.

Carcinogenesis. 2018 Sep 21. doi: 10.1093/carcin/bgy125. [Epub ahead of print]

PMID:
30247550
5.

Method for Biomonitoring DNA Adducts in Exfoliated Urinary Cells by Mass Spectrometry.

Yun BH, Bellamri M, Rosenquist TA, Turesky RJ.

Anal Chem. 2018 Aug 21;90(16):9943-9950. doi: 10.1021/acs.analchem.8b02170. Epub 2018 Jul 30.

PMID:
30001485
6.

DNA adducts: Formation, biological effects, and new biospecimens for mass spectrometric measurements in humans.

Hwa Yun B, Guo J, Bellamri M, Turesky RJ.

Mass Spectrom Rev. 2018 Jun 11. doi: 10.1002/mas.21570. [Epub ahead of print] Review.

PMID:
29889312
7.

Formalin-Fixed Paraffin-Embedded Tissues-An Untapped Biospecimen for Biomonitoring DNA Adducts by Mass Spectrometry.

Yun BH, Guo J, Turesky RJ.

Toxics. 2018 Jun 1;6(2). pii: E30. doi: 10.3390/toxics6020030. Review.

8.

Metabolic Activation of the Cooked Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine in Human Prostate.

Bellamri M, Xiao S, Murugan P, Weight CJ, Turesky RJ.

Toxicol Sci. 2018 Jun 1;163(2):543-556. doi: 10.1093/toxsci/kfy060.

PMID:
29596660
9.

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy.

Springer SU, Chen CH, Rodriguez Pena MDC, Li L, Douville C, Wang Y, Cohen JD, Taheri D, Silliman N, Schaefer J, Ptak J, Dobbyn L, Papoli M, Kinde I, Afsari B, Tregnago AC, Bezerra SM, VandenBussche C, Fujita K, Ertoy D, Cunha IW, Yu L, Bivalacqua TJ, Grollman AP, Diaz LA, Karchin R, Danilova L, Huang CY, Shun CT, Turesky RJ, Yun BH, Rosenquist TA, Pu YS, Hruban RH, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Dickman KG, Netto GJ.

Elife. 2018 Mar 20;7. pii: e32143. doi: 10.7554/eLife.32143. Erratum in: Elife. 2018 Nov 12;7:.

10.

A Rapid Throughput Method To Extract DNA from Formalin-Fixed Paraffin-Embedded Tissues for Biomonitoring Carcinogenic DNA Adducts.

Yun BH, Xiao S, Yao L, Krishnamachari S, Rosenquist TA, Dickman KG, Grollman AP, Murugan P, Weight CJ, Turesky RJ.

Chem Res Toxicol. 2017 Dec 18;30(12):2130-2139. doi: 10.1021/acs.chemrestox.7b00218. Epub 2017 Nov 27.

PMID:
29120619
11.

Data-Independent Mass Spectrometry Approach for Screening and Identification of DNA Adducts.

Guo J, Villalta PW, Turesky RJ.

Anal Chem. 2017 Nov 7;89(21):11728-11736. doi: 10.1021/acs.analchem.7b03208. Epub 2017 Oct 18.

12.
13.

Call for Papers on Mass Spectrometry and Biomarkers in Human Population Studies.

Turesky RJ.

Chem Res Toxicol. 2017 Feb 20;30(2):487. doi: 10.1021/acs.chemrestox.6b00431. No abstract available.

PMID:
28215092
14.

Biomonitoring DNA Adducts of Cooked Meat Carcinogens in Human Prostate by Nano Liquid Chromatography-High Resolution Tandem Mass Spectrometry: Identification of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine DNA Adduct.

Xiao S, Guo J, Yun BH, Villalta PW, Krishna S, Tejpaul R, Murugan P, Weight CJ, Turesky RJ.

Anal Chem. 2016 Dec 20;88(24):12508-12515. doi: 10.1021/acs.analchem.6b04157. Epub 2016 Dec 1.

15.

Introduction: Mass Spectrometry and Emerging Technologies for Biomarker Discovery in the Assessment of Human Health and Disease.

Isin EM, Turesky RJ.

Chem Res Toxicol. 2016 Dec 19;29(12):1901-1902. No abstract available.

PMID:
27989143
16.

Biomonitoring Human Albumin Adducts: The Past, the Present, and the Future.

Sabbioni G, Turesky RJ.

Chem Res Toxicol. 2017 Jan 17;30(1):332-366. doi: 10.1021/acs.chemrestox.6b00366. Epub 2016 Dec 18.

17.

Mass Spectrometric Characterization of an Acid-Labile Adduct Formed with 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and Albumin in Humans.

Wang Y, Villalta PW, Peng L, Dingley K, Malfatti MA, Turteltaub KW, Turesky RJ.

Chem Res Toxicol. 2017 Feb 20;30(2):705-714. doi: 10.1021/acs.chemrestox.6b00426. Epub 2017 Jan 18.

18.

Metabolism of the Tobacco Carcinogen 2-Amino-9H-pyrido[2,3-b]indole (AαC) in Primary Human Hepatocytes.

Bellamri M, Le Hegarat L, Turesky RJ, Langouët S.

Chem Res Toxicol. 2017 Feb 20;30(2):657-668. doi: 10.1021/acs.chemrestox.6b00394. Epub 2016 Dec 15.

19.

Human T lymphocytes bioactivate heterocyclic aromatic amines by forming DNA adducts.

Bellamri M, Le Hegarat L, Vernhet L, Baffet G, Turesky RJ, Langouët S.

Environ Mol Mutagen. 2016 Dec;57(9):656-667. doi: 10.1002/em.22059. Epub 2016 Nov 1.

20.

Human Biomonitoring of DNA Adducts by Ion Trap Multistage Mass Spectrometry.

Guo J, Turesky RJ.

Curr Protoc Nucleic Acid Chem. 2016 Sep 1;66:7.24.1-7.24.25. doi: 10.1002/cpnc.12.

21.

Aristolochic Acid in the Etiology of Renal Cell Carcinoma.

Hoang ML, Chen CH, Chen PC, Roberts NJ, Dickman KG, Yun BH, Turesky RJ, Pu YS, Vogelstein B, Papadopoulos N, Grollman AP, Kinzler KW, Rosenquist TA.

Cancer Epidemiol Biomarkers Prev. 2016 Dec;25(12):1600-1608. Epub 2016 Aug 23.

22.

Dose validation of PhIP hair level as a biomarker of heterocyclic aromatic amines exposure: a feeding study.

Le Marchand L, Yonemori K, White KK, Franke AA, Wilkens LR, Turesky RJ.

Carcinogenesis. 2016 Jul;37(7):685-691. doi: 10.1093/carcin/bgw049. Epub 2016 Apr 25.

23.

Multiclass Carcinogenic DNA Adduct Quantification in Formalin-Fixed Paraffin-Embedded Tissues by Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry.

Guo J, Yun BH, Upadhyaya P, Yao L, Krishnamachari S, Rosenquist TA, Grollman AP, Turesky RJ.

Anal Chem. 2016 May 3;88(9):4780-7. doi: 10.1021/acs.analchem.6b00124. Epub 2016 Apr 15.

24.

Bioactivation of Heterocyclic Aromatic Amines by UDP Glucuronosyltransferases.

Cai T, Yao L, Turesky RJ.

Chem Res Toxicol. 2016 May 16;29(5):879-91. doi: 10.1021/acs.chemrestox.6b00046. Epub 2016 Apr 18.

25.

Novel Transgenic Mouse Model for Studying Human Serum Albumin as a Biomarker of Carcinogenic Exposure.

Sheng J, Wang Y, Turesky RJ, Kluetzman K, Zhang QY, Ding X.

Chem Res Toxicol. 2016 May 16;29(5):797-809. doi: 10.1021/acs.chemrestox.5b00529. Epub 2016 Apr 14.

26.

Methemoglobin Formation and Characterization of Hemoglobin Adducts of Carcinogenic Aromatic Amines and Heterocyclic Aromatic Amines.

Pathak KV, Chiu TL, Amin EA, Turesky RJ.

Chem Res Toxicol. 2016 Mar 21;29(3):255-69. doi: 10.1021/acs.chemrestox.5b00418. Epub 2016 Feb 22.

27.

Comparative DNA adduct formation and induction of colonic aberrant crypt foci in mice exposed to 2-amino-9H-pyrido[2,3-b]indole, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline, and azoxymethane.

Kim S, Guo J, O'Sullivan MG, Gallaher DD, Turesky RJ.

Environ Mol Mutagen. 2016 Mar;57(2):125-36. doi: 10.1002/em.21993. Epub 2016 Jan 6.

28.

Aristolochic acid exposure in Romania and implications for renal cell carcinoma.

Turesky RJ, Yun BH, Brennan P, Mates D, Jinga V, Harnden P, Banks RE, Blanche H, Bihoreau MT, Chopard P, Letourneau L, Lathrop GM, Scelo G.

Br J Cancer. 2016 Jan 12;114(1):76-80. doi: 10.1038/bjc.2015.402. Epub 2015 Dec 10.

29.

Effect of Cytochrome P450 Reductase Deficiency on 2-Amino-9H-pyrido[2,3-b]indole Metabolism and DNA Adduct Formation in Liver and Extrahepatic Tissues of Mice.

Turesky RJ, Konorev D, Fan X, Tang Y, Yao L, Ding X, Xie F, Zhu Y, Zhang QY.

Chem Res Toxicol. 2015 Dec 21;28(12):2400-10. doi: 10.1021/acs.chemrestox.5b00405. Epub 2015 Dec 3.

30.

Measurement of the Heterocyclic Amines 2-Amino-9H-pyrido[2,3-b]indole and 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Urine: Effects of Cigarette Smoking.

Konorev D, Koopmeiners JS, Tang Y, Franck Thompson EA, Jensen JA, Hatsukami DK, Turesky RJ.

Chem Res Toxicol. 2015 Dec 21;28(12):2390-9. doi: 10.1021/acs.chemrestox.5b00401. Epub 2015 Dec 3.

31.

New Approaches for Biomonitoring Exposure to the Human Carcinogen Aristolochic Acid.

Yun BH, Sidorenko VS, Rosenquist TA, Dickman KG, Grollman AP, Turesky RJ.

Toxicol Res (Camb). 2015 Jul 1;4(4):763-776.

32.

Characterization of nitrogen mustard formamidopyrimidine adduct formation of bis(2-chloroethyl)ethylamine with calf thymus DNA and a human mammary cancer cell line.

Gruppi F, Hejazi L, Christov PP, Krishnamachari S, Turesky RJ, Rizzo CJ.

Chem Res Toxicol. 2015 Sep 21;28(9):1850-60. doi: 10.1021/acs.chemrestox.5b00297. Epub 2015 Sep 1.

33.

Caffeine Cytochrome P450 1A2 Metabolic Phenotype Does Not Predict the Metabolism of Heterocyclic Aromatic Amines in Humans.

Turesky RJ, White KK, Wilkens LR, Le Marchand L.

Chem Res Toxicol. 2015 Aug 17;28(8):1603-15. doi: 10.1021/acs.chemrestox.5b00177. Epub 2015 Aug 6.

34.
35.

2-Amino-9H-pyrido[2,3-b]indole (AαC) Adducts and Thiol Oxidation of Serum Albumin as Potential Biomarkers of Tobacco Smoke.

Pathak KV, Bellamri M, Wang Y, Langouët S, Turesky RJ.

J Biol Chem. 2015 Jun 26;290(26):16304-18. doi: 10.1074/jbc.M115.646539. Epub 2015 May 7.

36.

Mass Spectrometric Characterization of Human Serum Albumin Adducts Formed with N-Oxidized Metabolites of 2-Amino-1-methylphenylimidazo[4,5-b]pyridine in Human Plasma and Hepatocytes.

Wang Y, Peng L, Bellamri M, Langouët S, Turesky RJ.

Chem Res Toxicol. 2015 May 18;28(5):1045-59. doi: 10.1021/acs.chemrestox.5b00075. Epub 2015 Apr 10.

37.

Simultaneous detection of multiple DNA adducts in human lung samples by isotope-dilution UPLC-MS/MS.

Monien BH, Schumacher F, Herrmann K, Glatt H, Turesky RJ, Chesné C.

Anal Chem. 2015 Jan 6;87(1):641-8. doi: 10.1021/ac503803m. Epub 2014 Dec 8.

38.

Formalin-fixed paraffin-embedded tissue as a source for quantitation of carcinogen DNA adducts: aristolochic acid as a prototype carcinogen.

Yun BH, Yao L, Jelaković B, Nikolić J, Dickman KG, Grollman AP, Rosenquist TA, Turesky RJ.

Carcinogenesis. 2014 Sep;35(9):2055-61. doi: 10.1093/carcin/bgu101. Epub 2014 Apr 28.

40.

DNA adductomics.

Balbo S, Turesky RJ, Villalta PW.

Chem Res Toxicol. 2014 Mar 17;27(3):356-66. doi: 10.1021/tx4004352. Epub 2014 Feb 25. Review.

41.

Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing.

Hoang ML, Chen CH, Sidorenko VS, He J, Dickman KG, Yun BH, Moriya M, Niknafs N, Douville C, Karchin R, Turesky RJ, Pu YS, Vogelstein B, Papadopoulos N, Grollman AP, Kinzler KW, Rosenquist TA.

Sci Transl Med. 2013 Aug 7;5(197):197ra102. doi: 10.1126/scitranslmed.3006200.

42.

DNA adducts of the tobacco carcinogens 2-amino-9H-pyrido[2,3-b]indole and 4-aminobiphenyl are formed at environmental exposure levels and persist in human hepatocytes.

Nauwelaërs G, Bellamri M, Fessard V, Turesky RJ, Langouët S.

Chem Res Toxicol. 2013 Sep 16;26(9):1367-77. doi: 10.1021/tx4002226. Epub 2013 Aug 16.

43.

Human formalin-fixed paraffin-embedded tissues: an untapped specimen for biomonitoring of carcinogen DNA adducts by mass spectrometry.

Yun BH, Rosenquist TA, Nikolić J, Dragičević D, Tomić K, Jelaković B, Dickman KG, Grollman AP, Turesky RJ.

Anal Chem. 2013 May 7;85(9):4251-8. doi: 10.1021/ac400612x. Epub 2013 Apr 10.

44.

DNA adduct formation of 2-amino-9H-pyrido[2,3-b]indole and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline in mouse liver and extrahepatic tissues during a subchronic feeding study.

Tang Y, Kassie F, Qian X, Ansha B, Turesky RJ.

Toxicol Sci. 2013 Jun;133(2):248-58. doi: 10.1093/toxsci/kft077. Epub 2013 Mar 27.

45.

Biomonitoring the cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in hair: impact of exposure, hair pigmentation, and cytochrome P450 1A2 phenotype.

Turesky RJ, Liu L, Gu D, Yonemori KM, White KK, Wilkens LR, Le Marchand L.

Cancer Epidemiol Biomarkers Prev. 2013 Mar;22(3):356-64. doi: 10.1158/1055-9965.EPI-12-1206. Epub 2013 Jan 17.

46.

Capturing labile sulfenamide and sulfinamide serum albumin adducts of carcinogenic arylamines by chemical oxidation.

Peng L, Turesky RJ.

Anal Chem. 2013 Jan 15;85(2):1065-72. doi: 10.1021/ac3028273. Epub 2012 Dec 28.

47.

Biomonitoring the cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in canine fur.

Gu D, Neuman ZL, Modiano JF, Turesky RJ.

J Agric Food Chem. 2012 Sep 12;60(36):9371-5. doi: 10.1021/jf302969h. Epub 2012 Aug 29.

48.

Mapping serum albumin adducts of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by data-dependent tandem mass spectrometry.

Peng L, Dasari S, Tabb DL, Turesky RJ.

Chem Res Toxicol. 2012 Oct 15;25(10):2179-93. doi: 10.1021/tx300253j. Epub 2012 Aug 14. Erratum in: Chem Res Toxicol. 2013 Feb 18;26(2):300.

49.

Genetic and epigenetic regulation of AHR gene expression in MCF-7 breast cancer cells: role of the proximal promoter GC-rich region.

Englert NA, Turesky RJ, Han W, Bessette EE, Spivack SD, Caggana M, Spink DC, Spink BC.

Biochem Pharmacol. 2012 Sep 1;84(5):722-35. doi: 10.1016/j.bcp.2012.06.013. Epub 2012 Jun 21.

50.

Biomonitoring of aristolactam-DNA adducts in human tissues using ultra-performance liquid chromatography/ion-trap mass spectrometry.

Yun BH, Rosenquist TA, Sidorenko V, Iden CR, Chen CH, Pu YS, Bonala R, Johnson F, Dickman KG, Grollman AP, Turesky RJ.

Chem Res Toxicol. 2012 May 21;25(5):1119-31. doi: 10.1021/tx3000889. Epub 2012 May 4.

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