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Items: 1 to 50 of 187

1.

Lipophosphoglycan polymorphisms do not affect Leishmania amazonensis development in the permissive vectors Lutzomyia migonei and Lutzomyia longipalpis.

Nogueira PM, Guimarães AC, Assis RR, Sadlova J, Myskova J, Pruzinova K, Hlavackova J, Turco SJ, Torrecilhas AC, Volf P, Soares RP.

Parasit Vectors. 2017 Dec 16;10(1):608. doi: 10.1186/s13071-017-2568-8.

2.

Genetic metabolic complementation establishes a requirement for GDP-fucose in Leishmania.

Guo H, Novozhilova NM, Bandini G, Turco SJ, Ferguson MAJ, Beverley SM.

J Biol Chem. 2017 Jun 23;292(25):10696-10708. doi: 10.1074/jbc.M117.778480. Epub 2017 May 2.

3.

Lipophosphoglycans from Leishmania amazonensis Strains Display Immunomodulatory Properties via TLR4 and Do Not Affect Sand Fly Infection.

Nogueira PM, Assis RR, Torrecilhas AC, Saraiva EM, Pessoa NL, Campos MA, Marialva EF, Ríos-Velasquez CM, Pessoa FA, Secundino NF, Rugani JN, Nieves E, Turco SJ, Melo MN, Soares RP.

PLoS Negl Trop Dis. 2016 Aug 10;10(8):e0004848. doi: 10.1371/journal.pntd.0004848. eCollection 2016 Aug.

4.

Differential Impact of LPG-and PG-Deficient Leishmania major Mutants on the Immune Response of Human Dendritic Cells.

Favila MA, Geraci NS, Jayakumar A, Hickerson S, Mostrom J, Turco SJ, Beverley SM, McDowell MA.

PLoS Negl Trop Dis. 2015 Dec 2;9(12):e0004238. doi: 10.1371/journal.pntd.0004238. eCollection 2015 Dec.

5.

Characterization of a ricin-resistant mutant of Leishmania donovani that expresses lipophosphoglycan.

Phillips MR, Turco SJ.

Glycobiology. 2015 Apr;25(4):428-37. doi: 10.1093/glycob/cwu130. Epub 2014 Dec 3.

6.

Leishmania promastigotes induce cytokine secretion in macrophages through the degradation of synaptotagmin XI.

Arango Duque G, Fukuda M, Turco SJ, Stäger S, Descoteaux A.

J Immunol. 2014 Sep 1;193(5):2363-72. doi: 10.4049/jimmunol.1303043. Epub 2014 Jul 25.

7.

Structural comparison of lipophosphoglycan from Leishmania turanica and L. major, two species transmitted by Phlebotomus papatasi.

Volf P, Nogueira PM, Myskova J, Turco SJ, Soares RP.

Parasitol Int. 2014 Oct;63(5):683-6. doi: 10.1016/j.parint.2014.05.004. Epub 2014 May 23.

PMID:
24863491
8.

Two biochemically distinct lipophosphoglycans from Leishmania braziliensis and Leishmania infantum trigger different innate immune responses in murine macrophages.

Ibraim IC, de Assis RR, Pessoa NL, Campos MA, Melo MN, Turco SJ, Soares RP.

Parasit Vectors. 2013 Mar 7;6:54. doi: 10.1186/1756-3305-6-54.

9.

Glycoinositolphospholipids from Leishmania braziliensis and L. infantum: modulation of innate immune system and variations in carbohydrate structure.

Assis RR, Ibraim IC, Noronha FS, Turco SJ, Soares RP.

PLoS Negl Trop Dis. 2012;6(2):e1543. doi: 10.1371/journal.pntd.0001543. Epub 2012 Feb 28.

10.

Glycoconjugates in New World species of Leishmania: polymorphisms in lipophosphoglycan and glycoinositolphospholipids and interaction with hosts.

de Assis RR, Ibraim IC, Nogueira PM, Soares RP, Turco SJ.

Biochim Biophys Acta. 2012 Sep;1820(9):1354-65. doi: 10.1016/j.bbagen.2011.11.001. Epub 2011 Nov 7. Review.

PMID:
22093608
11.

Exclusion of synaptotagmin V at the phagocytic cup by Leishmania donovani lipophosphoglycan results in decreased promastigote internalization.

Vinet AF, Jananji S, Turco SJ, Fukuda M, Descoteaux A.

Microbiology. 2011 Sep;157(Pt 9):2619-28. doi: 10.1099/mic.0.050252-0. Epub 2011 Jun 16.

PMID:
21680635
12.

Leishmania infantum: Lipophosphoglycan intraspecific variation and interaction with vertebrate and invertebrate hosts.

Coelho-Finamore JM, Freitas VC, Assis RR, Melo MN, Novozhilova N, Secundino NF, Pimenta PF, Turco SJ, Soares RP.

Int J Parasitol. 2011 Mar;41(3-4):333-42. doi: 10.1016/j.ijpara.2010.10.004. Epub 2010 Nov 27. Erratum in: Int J Parasitol. 2011 Jun;41(7):811-2.

13.

Leishmania major survival in selective Phlebotomus papatasi sand fly vector requires a specific SCG-encoded lipophosphoglycan galactosylation pattern.

Dobson DE, Kamhawi S, Lawyer P, Turco SJ, Beverley SM, Sacks DL.

PLoS Pathog. 2010 Nov 11;6(11):e1001185. doi: 10.1371/journal.ppat.1001185.

14.

Retention and loss of RNA interference pathways in trypanosomatid protozoans.

Lye LF, Owens K, Shi H, Murta SM, Vieira AC, Turco SJ, Tschudi C, Ullu E, Beverley SM.

PLoS Pathog. 2010 Oct 28;6(10):e1001161. doi: 10.1371/journal.ppat.1001161.

15.

Proteophosphoglycan confers resistance of Leishmania major to midgut digestive enzymes induced by blood feeding in vector sand flies.

Secundino N, Kimblin N, Peters NC, Lawyer P, Capul AA, Beverley SM, Turco SJ, Sacks D.

Cell Microbiol. 2010 Jul;12(7):906-18. doi: 10.1111/j.1462-5822.2010.01439.x. Epub 2010 Jan 20.

16.

Differential midgut attachment of Leishmania (Viannia) braziliensis in the sand flies Lutzomyia (Nyssomyia) whitmani and Lutzomyia (Nyssomyia) intermedia.

Soares RP, Margonari C, Secundino NC, Macêdo ME, da Costa SM, Rangel EF, Pimenta PF, Turco SJ.

J Biomed Biotechnol. 2010;2010:439174. doi: 10.1155/2010/439174.

17.

The Leishmania donovani lipophosphoglycan excludes the vesicular proton-ATPase from phagosomes by impairing the recruitment of synaptotagmin V.

Vinet AF, Fukuda M, Turco SJ, Descoteaux A.

PLoS Pathog. 2009 Oct;5(10):e1000628. doi: 10.1371/journal.ppat.1000628. Epub 2009 Oct 16.

18.

Leishmania donovani lacking the Golgi GDP-Man transporter LPG2 exhibit attenuated virulence in mammalian hosts.

Gaur U, Showalter M, Hickerson S, Dalvi R, Turco SJ, Wilson ME, Beverley SM.

Exp Parasitol. 2009 Jul;122(3):182-91. doi: 10.1016/j.exppara.2009.03.014. Epub 2009 Mar 27.

20.

Two functionally divergent UDP-Gal nucleotide sugar transporters participate in phosphoglycan synthesis in Leishmania major.

Capul AA, Barron T, Dobson DE, Turco SJ, Beverley SM.

J Biol Chem. 2007 May 11;282(19):14006-17. Epub 2007 Mar 8.

21.

Leishmania major: Reactive oxygen species and interferon gamma induction by soluble lipophosphoglycan of stationary phase promastigotes.

Kavoosi G, Ardestani SK, Kariminia A, Abolhassani M, Turco SJ.

Exp Parasitol. 2006 Dec;114(4):323-8. Epub 2006 Jun 8.

PMID:
16759653
22.
23.

Quantitation of Leishmania lipophosphoglycan repeat units by capillary electrophoresis.

Barron TL, Turco SJ.

Biochim Biophys Acta. 2006 Apr;1760(4):710-4. Epub 2005 Nov 8.

PMID:
16310310
24.

Demonstration by heterologous expression that the Leishmania SCA1 gene encodes an arabinopyranosyltransferase.

Goswami M, Dobson DE, Beverley SM, Turco SJ.

Glycobiology. 2006 Mar;16(3):230-6. Epub 2005 Nov 4.

PMID:
16272216
25.

Leishmania donovani lipophosphoglycan disrupts phagosome microdomains in J774 macrophages.

Dermine JF, Goyette G, Houde M, Turco SJ, Desjardins M.

Cell Microbiol. 2005 Sep;7(9):1263-70.

PMID:
16098214
26.

Leishmania braziliensis: a novel mechanism in the lipophosphoglycan regulation during metacyclogenesis.

Soares RP, Cardoso TL, Barron T, Araújo MS, Pimenta PF, Turco SJ.

Int J Parasitol. 2005 Mar;35(3):245-53. Epub 2005 Jan 24.

PMID:
15722076
27.

A role for insect galectins in parasite survival.

Kamhawi S, Ramalho-Ortigao M, Pham VM, Kumar S, Lawyer PG, Turco SJ, Barillas-Mury C, Sacks DL, Valenzuela JG.

Cell. 2004 Oct 29;119(3):329-41.

28.

Reconstitution of GDP-mannose transport activity with purified Leishmania LPG2 protein in liposomes.

Segawa H, Soares RP, Kawakita M, Beverley SM, Turco SJ.

J Biol Chem. 2005 Jan 21;280(3):2028-35. Epub 2004 Nov 12.

29.

A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan.

Amprey JL, Im JS, Turco SJ, Murray HW, Illarionov PA, Besra GS, Porcelli SA, Späth GF.

J Exp Med. 2004 Oct 4;200(7):895-904.

30.

Leishmania tropica: intraspecific polymorphisms in lipophosphoglycan correlate with transmission by different Phlebotomus species.

Soares RP, Barron T, McCoy-Simandle K, Svobodova M, Warburg A, Turco SJ.

Exp Parasitol. 2004 May-Jun;107(1-2):105-14.

PMID:
15208044
32.

The LPG1 gene family of Leishmania major.

Zhang K, Barron T, Turco SJ, Beverley SM.

Mol Biochem Parasitol. 2004 Jul;136(1):11-23.

33.

Leishmania major-Phlebotomus duboscqi interactions: inhibition of anti-LPG antibodies and characterisation of two proteins with shared epitopes.

Tonui WK, Ngumbi PM, Mpoke SS, Orago AS, Mbati PA, Turco SJ, Mkoji GM.

East Afr Med J. 2004 Feb;81(2):97-103.

PMID:
15125094
34.
35.

The dendritic cell receptor DC-SIGN discriminates among species and life cycle forms of Leishmania.

Colmenares M, Corbí AL, Turco SJ, Rivas L.

J Immunol. 2004 Jan 15;172(2):1186-90.

36.

Control of Leishmania-sand fly interactions by polymorphisms in lipophosphoglycan structure.

Turco SJ, Sacks DL.

Methods Enzymol. 2003;363:377-81. No abstract available.

PMID:
14579590
37.

An in vitro system for developmental and genetic studies of Leishmania donovani phosphoglycans.

Goyard S, Segawa H, Gordon J, Showalter M, Duncan R, Turco SJ, Beverley SM.

Mol Biochem Parasitol. 2003 Aug 11;130(1):31-42.

PMID:
14550894
38.

Lutzomyia longipalpis (Diptera: Psychodidae: Phlebotominae): a review.

Soares RP, Turco SJ.

An Acad Bras Cienc. 2003 Sep;75(3):301-30. Epub 2003 Aug 25. Review. Erratum in: An Acad Bras Cienc. 2003 Dec;75(4):441.

39.

Persistence without pathology in phosphoglycan-deficient Leishmania major.

Späth GF, Lye LF, Segawa H, Sacks DL, Turco SJ, Beverley SM.

Science. 2003 Aug 29;301(5637):1241-3.

40.

Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major.

Zufferey R, Allen S, Barron T, Sullivan DR, Denny PW, Almeida IC, Smith DF, Turco SJ, Ferguson MA, Beverley SM.

J Biol Chem. 2003 Nov 7;278(45):44708-18. Epub 2003 Aug 27.

41.

The role(s) of lipophosphoglycan (LPG) in the establishment of Leishmania major infections in mammalian hosts.

Späth GF, Garraway LA, Turco SJ, Beverley SM.

Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9536-41. Epub 2003 Jul 17.

42.

Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila.

Lüders F, Segawa H, Stein D, Selva EM, Perrimon N, Turco SJ, Häcker U.

EMBO J. 2003 Jul 15;22(14):3635-44.

43.

Identification of genes encoding arabinosyltransferases (SCA) mediating developmental modifications of lipophosphoglycan required for sand fly transmission of leishmania major.

Dobson DE, Mengeling BJ, Cilmi S, Hickerson S, Turco SJ, Beverley SM.

J Biol Chem. 2003 Aug 1;278(31):28840-8. Epub 2003 May 15.

44.

Galactofuranose metabolism: a potential target for antimicrobial chemotherapy.

Pedersen LL, Turco SJ.

Cell Mol Life Sci. 2003 Feb;60(2):259-66. Review.

PMID:
12678491
45.

Functional identification of galactosyltransferases (SCGs) required for species-specific modifications of the lipophosphoglycan adhesin controlling Leishmania major-sand fly interactions.

Dobson DE, Scholtes LD, Valdez KE, Sullivan DR, Mengeling BJ, Cilmi S, Turco SJ, Beverley SM.

J Biol Chem. 2003 May 2;278(18):15523-31. Epub 2003 Feb 24.

46.
47.

Functional aspects of the Leishmania donovani lipophosphoglycan during macrophage infection.

Descoteaux A, Turco SJ.

Microbes Infect. 2002 Jul;4(9):975-81. Review.

PMID:
12106791
48.

Leishmania chagasi: lipophosphoglycan characterization and binding to the midgut of the sand fly vector Lutzomyia longipalpis.

Soares RP, Macedo ME, Ropert C, Gontijo NF, Almeida IC, Gazzinelli RT, Pimenta PF, Turco SJ.

Mol Biochem Parasitol. 2002 May;121(2):213-24.

PMID:
12034455
50.

Transmission blocking vaccine studies in leishmaniasis: I. Lipophosphoglycan is a promising transmission blocking vaccine molecule against cutaneous leishmaniasis.

Tonui WK, Mbati PA, Anjili CO, Orago AS, Turco SJ, Githure JI, Koech DK.

East Afr Med J. 2001 Feb;78(2):84-9.

PMID:
11682952

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