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Items: 16


Progesterone potentiates the growth inhibitory effects of calcitriol in endometrial cancer via suppression of CYP24A1.

Bokhari AA, Lee LR, Raboteau D, Turbov J, Rodriguez IV, Pike JW, Hamilton CA, Maxwell GL, Rodriguez GC, Syed V.

Oncotarget. 2016 Nov 22;7(47):77576-77590. doi: 10.18632/oncotarget.12725.


Progestins inhibit calcitriol-induced CYP24A1 and synergistically inhibit ovarian cancer cell viability: An opportunity for chemoprevention.

Rodriguez GC, Turbov J, Rosales R, Yoo J, Hunn J, Zappia KJ, Lund K, Barry CP, Rodriguez IV, Pike JW, Conrads TP, Darcy KM, Maxwell GL, Hamilton CA, Syed V, Thaete LG.

Gynecol Oncol. 2016 Oct;143(1):159-167. doi: 10.1016/j.ygyno.2016.04.022. Epub 2016 Jul 29.


Evidence of a chemopreventive effect of progestin unrelated to ovulation on reproductive tract cancers in the egg-laying hen.

Rodriguez GC, Barnes HJ, Anderson KE, Whitaker RS, Berchuck A, Petitte JN, Lancaster JM, Wenham RM, Turbov JM, Day R, Maxwell GL, Carver DK.

Cancer Prev Res (Phila). 2013 Dec;6(12):1283-92. doi: 10.1158/1940-6207.CAPR-12-0426. Epub 2013 Oct 17.


Progesterone enhances calcitriol antitumor activity by upregulating vitamin D receptor expression and promoting apoptosis in endometrial cancer cells.

Lee LR, Teng PN, Nguyen H, Hood BL, Kavandi L, Wang G, Turbov JM, Thaete LG, Hamilton CA, Maxwell GL, Rodriguez GC, Conrads TP, Syed V.

Cancer Prev Res (Phila). 2013 Jul;6(7):731-43. doi: 10.1158/1940-6207.CAPR-12-0493. Epub 2013 May 16.


Nonsteroidal antiinflammatory drugs and progestins synergistically enhance cell death in ovarian epithelial cells.

Rodriguez GC, Turbov JM, Berchuck A, Stack MS, Hurteau JA, Thaete LG, Barry CP.

Am J Obstet Gynecol. 2012 Mar;206(3):253.e1-9. doi: 10.1016/j.ajog.2011.11.012. Epub 2011 Nov 25.


Ovarian adenocarcinomas in the laying hen and women share similar alterations in p53, ras, and HER-2/neu.

Hakim AA, Barry CP, Barnes HJ, Anderson KE, Petitte J, Whitaker R, Lancaster JM, Wenham RM, Carver DK, Turbov J, Berchuck A, Kopelovich L, Rodriguez GC.

Cancer Prev Res (Phila). 2009 Feb;2(2):114-21. doi: 10.1158/1940-6207.CAPR-08-0065. Epub 2009 Jan 27. Erratum in: Cancer Prev Res (Phila Pa). 2009 Mar;2(3):283.


Progestin treatment induces apoptosis and modulates transforming growth factor-beta in the uterine endometrium.

Rodriguez GC, Rimel BJ, Watkin W, Turbov JM, Barry C, Du H, Maxwell GL, Cline JM.

Cancer Epidemiol Biomarkers Prev. 2008 Mar;17(3):578-84. doi: 10.1158/1055-9965.EPI-07-0551.


Granule-mediated killing: pathways for granzyme B-initiated apoptosis.

Talanian RV, Yang X, Turbov J, Seth P, Ghayur T, Casiano CA, Orth K, Froelich CJ.

J Exp Med. 1997 Oct 20;186(8):1323-31.


Human perforin: rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays.

Froelich CJ, Turbov J, Hanna W.

Biochem Biophys Res Commun. 1996 Dec 4;229(1):44-9.


New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis.

Froelich CJ, Orth K, Turbov J, Seth P, Gottlieb R, Babior B, Shah GM, Bleackley RC, Dixit VM, Hanna W.

J Biol Chem. 1996 Nov 15;271(46):29073-9.


Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes.

Froelich CJ, Zhang X, Turbov J, Hudig D, Winkler U, Hanna WL.

J Immunol. 1993 Dec 15;151(12):7161-71.


Rapid purification of cationic granule proteases: application to human granzymes.

Hanna WL, Zhang X, Turbov J, Winkler U, Hudig D, Froelich CJ.

Protein Expr Purif. 1993 Oct;4(5):398-404.


Soluble factors produced by isolated first-trimester chorionic villi directly inhibit proliferation of T cells.

Silver RK, Turbov JM, Beaird JA, Golbus J.

Am J Obstet Gynecol. 1990 Dec;163(6 Pt 1):1914-9.


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