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Items: 1 to 50 of 68

1.

Next-generation sequencing based detection of germline and somatic alterations in a patient with four metachronous primary tumors.

Martin M, Sabari JK, Turashvili G, Halpenny DF, Rizvi H, Shapnik N, Makker V.

Gynecol Oncol Rep. 2018 Apr 18;24:94-98. doi: 10.1016/j.gore.2018.04.004. eCollection 2018 May.

2.

Novel prognostic and predictive microRNA targets for triple-negative breast cancer.

Turashvili G, Lightbody ED, Tyryshkin K, SenGupta SK, Elliott BE, Madarnas Y, Ghaffari A, Day A, Nicol CJB.

FASEB J. 2018 May 29:fj201800120R. doi: 10.1096/fj.201800120R. [Epub ahead of print]

PMID:
29812973
3.

BRAFV600E mutations and immunohistochemical expression of VE1 protein in low-grade serous neoplasms of the ovary.

Turashvili G, Grisham RN, Chiang S, DeLair DF, Park KJ, Soslow RA, Murali R.

Histopathology. 2018 May 16. doi: 10.1111/his.13651. [Epub ahead of print]

PMID:
29770477
4.

Morphologic Features of Gastric-type Cervical Adenocarcinoma in Small Surgical and Cytology Specimens.

Turashvili G, Morency EG, Kracun M, DeLair DF, Chiang S, Soslow RA, Park KJ, Murali R.

Int J Gynecol Pathol. 2018 May 10. doi: 10.1097/PGP.0000000000000519. [Epub ahead of print]

PMID:
29750702
5.

Associations between genomic stratification of breast cancer and centrally reviewed tumour pathology in the METABRIC cohort.

Mukherjee A, Russell R, Chin SF, Liu B, Rueda OM, Ali HR, Turashvili G, Mahler-Araujo B, Ellis IO, Aparicio S, Caldas C, Provenzano E.

NPJ Breast Cancer. 2018 Mar 7;4:5. doi: 10.1038/s41523-018-0056-8. eCollection 2018.

6.

The 21-Gene Recurrence Score in Male Breast Cancer.

Turashvili G, Gonzalez-Loperena M, Brogi E, Dickler M, Norton L, Morrow M, Wen HY.

Ann Surg Oncol. 2018 Jun;25(6):1530-1535. doi: 10.1245/s10434-018-6411-z. Epub 2018 Mar 8.

PMID:
29520654
7.

Breast carcinoma with 21-gene recurrence score lower than 18: rate of locoregional recurrence in a large series with clinical follow-up.

Turashvili G, Brogi E, Morrow M, Dickler M, Norton L, Hudis C, Wen HY.

BMC Cancer. 2018 Jan 6;18(1):42. doi: 10.1186/s12885-017-3985-y.

8.

Corrigendum to "Brain metastasis in advanced serous borderline tumor of the ovary: A case presentation" [Gynecol. Oncol. Rep. 22 (2017) 9-12].

Martin M, Grisham RN, Turashvili G, Halpenny DF, Aghajanian CA, Makker V.

Gynecol Oncol Rep. 2017 Sep 29;22:118. doi: 10.1016/j.gore.2017.09.014. eCollection 2017 Nov.

9.

Tumor Heterogeneity in Breast Cancer.

Turashvili G, Brogi E.

Front Med (Lausanne). 2017 Dec 8;4:227. doi: 10.3389/fmed.2017.00227. eCollection 2017. Review.

10.

Brain metastasis in advanced serous borderline tumor of the ovary: A case presentation.

Martin M, Grisham RN, Turashvili G, Halpenny DF, Aghajanian CA, Makker V.

Gynecol Oncol Rep. 2017 Sep 6;22:9-12. doi: 10.1016/j.gore.2017.09.001. eCollection 2017 Nov. Erratum in: Gynecol Oncol Rep. 2017 Sep 29;22:118.

11.

21-Gene recurrence score and locoregional recurrence in lymph node-negative, estrogen receptor-positive breast cancer.

Turashvili G, Chou JF, Brogi E, Morrow M, Dickler M, Norton L, Hudis C, Wen HY.

Breast Cancer Res Treat. 2017 Nov;166(1):69-76. doi: 10.1007/s10549-017-4381-7. Epub 2017 Jul 12.

12.

The 21-gene recurrence score in special histologic subtypes of breast cancer with favorable prognosis.

Turashvili G, Brogi E, Morrow M, Hudis C, Dickler M, Norton L, Wen HY.

Breast Cancer Res Treat. 2017 Aug;165(1):65-76. doi: 10.1007/s10549-017-4326-1. Epub 2017 Jun 3.

PMID:
28577081
13.

A 64-Year-Old Male with Leg Pain.

Turashvili G, Varma S, SenGupta S, Rossiter JP.

Brain Pathol. 2016 Sep;26(5):677-8. doi: 10.1111/bpa.12420. No abstract available.

PMID:
27667802
14.

Erratum: The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes.

Pereira B, Chin SF, Rueda OM, Vollan HK, Provenzano E, Bardwell HA, Pugh M, Jones L, Russell R, Sammut SJ, Tsui DW, Liu B, Dawson SJ, Abraham J, Northen H, Peden JF, Mukherjee A, Turashvili G, Green AR, McKinney S, Oloumi A, Shah S, Rosenfeld N, Murphy L, Bentley DR, Ellis IO, Purushotham A, Pinder SE, Børresen-Dale AL, Earl HM, Pharoah PD, Ross MT, Aparicio S, Caldas C.

Nat Commun. 2016 Jun 6;7:11908. doi: 10.1038/ncomms11908. No abstract available.

15.

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes.

Pereira B, Chin SF, Rueda OM, Vollan HK, Provenzano E, Bardwell HA, Pugh M, Jones L, Russell R, Sammut SJ, Tsui DW, Liu B, Dawson SJ, Abraham J, Northen H, Peden JF, Mukherjee A, Turashvili G, Green AR, McKinney S, Oloumi A, Shah S, Rosenfeld N, Murphy L, Bentley DR, Ellis IO, Purushotham A, Pinder SE, Børresen-Dale AL, Earl HM, Pharoah PD, Ross MT, Aparicio S, Caldas C.

Nat Commun. 2016 May 10;7:11479. doi: 10.1038/ncomms11479.

16.

A distinct pre-existing inflammatory tumour microenvironment is associated with chemotherapy resistance in high-grade serous epithelial ovarian cancer.

Koti M, Siu A, Clément I, Bidarimath M, Turashvili G, Edwards A, Rahimi K, Mes-Masson AM, Squire JA.

Br J Cancer. 2015 Dec 22;113(12):1746. doi: 10.1038/bjc.2015.459. No abstract available.

17.

Human Papillomavirus-Related Ovarian Metastasis With Endocervical Adenocarcinoma: Report of 2 Cases and Review of Literature.

Turashvili G, Farmer P, Colgan T, Childs T.

J Low Genit Tract Dis. 2015 Oct;19(4):e60-3. doi: 10.1097/LGT.0000000000000146. Review.

PMID:
26360235
18.

Bilateral adrenal histoplasmosis in a man with chronic alcoholism.

Turashvili G, Cunningham KS.

J Microbiol Immunol Infect. 2016 Oct;49(5):797-798. doi: 10.1016/j.jmii.2015.02.660. Epub 2015 Mar 25. No abstract available.

19.

A distinct pre-existing inflammatory tumour microenvironment is associated with chemotherapy resistance in high-grade serous epithelial ovarian cancer.

Koti M, Siu A, Clément I, Bidarimath M, Turashvili G, Edwards A, Rahimi K, Mes-Masson AM, Squire JA.

Br J Cancer. 2015 Mar 31;112(7):1215-22. doi: 10.1038/bjc.2015.81. Erratum in: Br J Cancer. 2015 Dec 22;113(12):1746. Masson, A-M M [corrected to Mes-Masson, A-M].

20.

In vivo radioimaging of bradykinin receptor b1, a widely overexpressed molecule in human cancer.

Lin KS, Pan J, Amouroux G, Turashvili G, Mesak F, Hundal-Jabal N, Pourghiasian M, Lau J, Jenni S, Aparicio S, Bénard F.

Cancer Res. 2015 Jan 15;75(2):387-93. doi: 10.1158/0008-5472.CAN-14-1603. Epub 2014 Dec 8.

21.

Mucinous metaplasia of the endometrium: current concepts.

Turashvili G, Childs T.

Gynecol Oncol. 2015 Feb;136(2):389-93. doi: 10.1016/j.ygyno.2014.12.003. Epub 2014 Dec 6. Review.

PMID:
25485781
22.

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.

Vollan HK, Rueda OM, Chin SF, Curtis C, Turashvili G, Shah S, Lingjærde OC, Yuan Y, Ng CK, Dunning MJ, Dicks E, Provenzano E, Sammut S, McKinney S, Ellis IO, Pinder S, Purushotham A, Murphy LC, Kristensen VN; METABRIC Group, Brenton JD, Pharoah PD, Børresen-Dale AL, Aparicio S, Caldas C.

Mol Oncol. 2015 Jan;9(1):115-27. doi: 10.1016/j.molonc.2014.07.019. Epub 2014 Aug 8.

23.

First fatal case of systemic suppurative/necrotizing granulomatous disease following etanercept therapy for psoriasis.

Turashvili G, Farmer P.

J Dermatolog Treat. 2015 Apr;26(2):124-7. doi: 10.3109/09546634.2014.906035. Epub 2014 Apr 8.

PMID:
24646144
24.

The velvet myocardium: potential harbinger of death in acute myocarditis?

Johri AM, Barake W, Crawford B, Turashvili G, Rossiter J, Evans GA.

Can J Cardiol. 2013 Dec;29(12):1742.e25-7. doi: 10.1016/j.cjca.2013.09.007.

PMID:
24267815
25.

TDP1 and PARP1 deficiency are cytotoxic to rhabdomyosarcoma cells.

Fam HK, Walton C, Mitra SA, Chowdhury M, Osborne N, Choi K, Sun G, Wong PC, O'Sullivan MJ, Turashvili G, Aparicio S, Triche TJ, Bond M, Pallen CJ, Boerkoel CF.

Mol Cancer Res. 2013 Oct;11(10):1179-92. doi: 10.1158/1541-7786.MCR-12-0575. Epub 2013 Aug 2.

26.

The shaping and functional consequences of the microRNA landscape in breast cancer.

Dvinge H, Git A, Gräf S, Salmon-Divon M, Curtis C, Sottoriva A, Zhao Y, Hirst M, Armisen J, Miska EA, Chin SF, Provenzano E, Turashvili G, Green A, Ellis I, Aparicio S, Caldas C.

Nature. 2013 May 16;497(7449):378-82. doi: 10.1038/nature12108. Epub 2013 May 5.

PMID:
23644459
27.

Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling.

Yuan Y, Failmezger H, Rueda OM, Ali HR, Gräf S, Chin SF, Schwarz RF, Curtis C, Dunning MJ, Bardwell H, Johnson N, Doyle S, Turashvili G, Provenzano E, Aparicio S, Caldas C, Markowetz F.

Sci Transl Med. 2012 Oct 24;4(157):157ra143. doi: 10.1126/scitranslmed.3004330. Erratum in: Sci Transl Med. 2012 Oct 24;4(157):161er6.

28.

The landscape of cancer genes and mutational processes in breast cancer.

Stephens PJ, Tarpey PS, Davies H, Van Loo P, Greenman C, Wedge DC, Nik-Zainal S, Martin S, Varela I, Bignell GR, Yates LR, Papaemmanuil E, Beare D, Butler A, Cheverton A, Gamble J, Hinton J, Jia M, Jayakumar A, Jones D, Latimer C, Lau KW, McLaren S, McBride DJ, Menzies A, Mudie L, Raine K, Rad R, Chapman MS, Teague J, Easton D, Langerød A; Oslo Breast Cancer Consortium (OSBREAC), Lee MT, Shen CY, Tee BT, Huimin BW, Broeks A, Vargas AC, Turashvili G, Martens J, Fatima A, Miron P, Chin SF, Thomas G, Boyault S, Mariani O, Lakhani SR, van de Vijver M, van 't Veer L, Foekens J, Desmedt C, Sotiriou C, Tutt A, Caldas C, Reis-Filho JS, Aparicio SA, Salomon AV, Børresen-Dale AL, Richardson AL, Campbell PJ, Futreal PA, Stratton MR.

Nature. 2012 May 16;486(7403):400-4. doi: 10.1038/nature11017.

29.

Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer.

Ha G, Roth A, Lai D, Bashashati A, Ding J, Goya R, Giuliany R, Rosner J, Oloumi A, Shumansky K, Chin SF, Turashvili G, Hirst M, Caldas C, Marra MA, Aparicio S, Shah SP.

Genome Res. 2012 Oct;22(10):1995-2007. doi: 10.1101/gr.137570.112. Epub 2012 May 25.

30.

PPM1H is a p27 phosphatase implicated in trastuzumab resistance.

Lee-Hoeflich ST, Pham TQ, Dowbenko D, Munroe X, Lee J, Li L, Zhou W, Haverty PM, Pujara K, Stinson J, Chan SM, Eastham-Anderson J, Pandita A, Seshagiri S, Hoeflich KP, Turashvili G, Gelmon KA, Aparicio SA, Davis DP, Sliwkowski MX, Stern HM.

Cancer Discov. 2011 Sep;1(4):326-37. doi: 10.1158/2159-8290.CD-11-0062. Epub 2011 Jul 20.

31.

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.

Curtis C, Shah SP, Chin SF, Turashvili G, Rueda OM, Dunning MJ, Speed D, Lynch AG, Samarajiwa S, Yuan Y, Gräf S, Ha G, Haffari G, Bashashati A, Russell R, McKinney S; METABRIC Group, Langerød A, Green A, Provenzano E, Wishart G, Pinder S, Watson P, Markowetz F, Murphy L, Ellis I, Purushotham A, Børresen-Dale AL, Brenton JD, Tavaré S, Caldas C, Aparicio S.

Nature. 2012 Apr 18;486(7403):346-52. doi: 10.1038/nature10983.

32.

The clonal and mutational evolution spectrum of primary triple-negative breast cancers.

Shah SP, Roth A, Goya R, Oloumi A, Ha G, Zhao Y, Turashvili G, Ding J, Tse K, Haffari G, Bashashati A, Prentice LM, Khattra J, Burleigh A, Yap D, Bernard V, McPherson A, Shumansky K, Crisan A, Giuliany R, Heravi-Moussavi A, Rosner J, Lai D, Birol I, Varhol R, Tam A, Dhalla N, Zeng T, Ma K, Chan SK, Griffith M, Moradian A, Cheng SW, Morin GB, Watson P, Gelmon K, Chia S, Chin SF, Curtis C, Rueda OM, Pharoah PD, Damaraju S, Mackey J, Hoon K, Harkins T, Tadigotla V, Sigaroudinia M, Gascard P, Tlsty T, Costello JF, Meyer IM, Eaves CJ, Wasserman WW, Jones S, Huntsman D, Hirst M, Caldas C, Marra MA, Aparicio S.

Nature. 2012 Apr 4;486(7403):395-9. doi: 10.1038/nature10933.

33.

JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data.

Roth A, Ding J, Morin R, Crisan A, Ha G, Giuliany R, Bashashati A, Hirst M, Turashvili G, Oloumi A, Marra MA, Aparicio S, Shah SP.

Bioinformatics. 2012 Apr 1;28(7):907-13. doi: 10.1093/bioinformatics/bts053. Epub 2012 Jan 27.

34.

Mll5 is required for normal spermatogenesis.

Yap DB, Walker DC, Prentice LM, McKinney S, Turashvili G, Mooslehner-Allen K, de Algara TR, Fee J, de Tassigny Xd, Colledge WH, Aparicio S.

PLoS One. 2011;6(11):e27127. doi: 10.1371/journal.pone.0027127. Epub 2011 Nov 1.

35.

Nucleic acid quantity and quality from paraffin blocks: defining optimal fixation, processing and DNA/RNA extraction techniques.

Turashvili G, Yang W, McKinney S, Kalloger S, Gale N, Ng Y, Chow K, Bell L, Lorette J, Carrier M, Luk M, Aparicio S, Huntsman D, Yip S.

Exp Mol Pathol. 2012 Feb;92(1):33-43. doi: 10.1016/j.yexmp.2011.09.013. Epub 2011 Sep 21.

PMID:
21963600
36.

Insulin-like growth factor receptor (IGF-1R) in breast cancer subtypes.

Yerushalmi R, Gelmon KA, Leung S, Gao D, Cheang M, Pollak M, Turashvili G, Gilks BC, Kennecke H.

Breast Cancer Res Treat. 2012 Feb;132(1):131-42. doi: 10.1007/s10549-011-1529-8. Epub 2011 May 15.

PMID:
21574055
37.

The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent.

Prentice LM, d'Anglemont de Tassigny X, McKinney S, Ruiz de Algara T, Yap D, Turashvili G, Poon S, Sutcliffe M, Allard P, Burleigh A, Fee J, Huntsman DG, Colledge WH, Aparicio SA.

BMC Genomics. 2011 Apr 28;12:209. doi: 10.1186/1471-2164-12-209.

38.

ARID1A mutations in endometriosis-associated ovarian carcinomas.

Wiegand KC, Shah SP, Al-Agha OM, Zhao Y, Tse K, Zeng T, Senz J, McConechy MK, Anglesio MS, Kalloger SE, Yang W, Heravi-Moussavi A, Giuliany R, Chow C, Fee J, Zayed A, Prentice L, Melnyk N, Turashvili G, Delaney AD, Madore J, Yip S, McPherson AW, Ha G, Bell L, Fereday S, Tam A, Galletta L, Tonin PN, Provencher D, Miller D, Jones SJ, Moore RA, Morin GB, Oloumi A, Boyd N, Aparicio SA, Shih IeM, Mes-Masson AM, Bowtell DD, Hirst M, Gilks B, Marra MA, Huntsman DG.

N Engl J Med. 2010 Oct 14;363(16):1532-43. doi: 10.1056/NEJMoa1008433. Epub 2010 Sep 8.

39.

P-cadherin expression as a prognostic biomarker in a 3992 case tissue microarray series of breast cancer.

Turashvili G, McKinney SE, Goktepe O, Leung SC, Huntsman DG, Gelmon KA, Los G, Rejto PA, Aparicio SA.

Mod Pathol. 2011 Jan;24(1):64-81. doi: 10.1038/modpathol.2010.189. Epub 2010 Sep 17.

40.

Immunohistochemical expression of BRCA1 protein in invasive ductal carcinoma of the breast.

Burkadze G, Khardzeishvili O, Gudadze M, Tsikhiseli G, Turashvili G.

Georgian Med News. 2010 Jul-Aug;(184-185):51-60.

PMID:
20834076
41.

BCL2 in breast cancer: a favourable prognostic marker across molecular subtypes and independent of adjuvant therapy received.

Dawson SJ, Makretsov N, Blows FM, Driver KE, Provenzano E, Le Quesne J, Baglietto L, Severi G, Giles GG, McLean CA, Callagy G, Green AR, Ellis I, Gelmon K, Turashvili G, Leung S, Aparicio S, Huntsman D, Caldas C, Pharoah P.

Br J Cancer. 2010 Aug 24;103(5):668-75. doi: 10.1038/sj.bjc.6605736. Epub 2010 Jul 27. Erratum in: Br J Cancer. 2010 Sep 28;103(7):1137.

42.

Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy.

Dumont N, Crawford YG, Sigaroudinia M, Nagrani SS, Wilson MB, Buehring GC, Turashvili G, Aparicio S, Gauthier ML, Fordyce CA, McDermott KM, Tlsty TD.

Breast Cancer Res. 2009;11(6):R87. doi: 10.1186/bcr2457. Epub 2009 Dec 8.

43.

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution.

Shah SP, Morin RD, Khattra J, Prentice L, Pugh T, Burleigh A, Delaney A, Gelmon K, Guliany R, Senz J, Steidl C, Holt RA, Jones S, Sun M, Leung G, Moore R, Severson T, Taylor GA, Teschendorff AE, Tse K, Turashvili G, Varhol R, Warren RL, Watson P, Zhao Y, Caldas C, Huntsman D, Hirst M, Marra MA, Aparicio S.

Nature. 2009 Oct 8;461(7265):809-13. doi: 10.1038/nature08489.

PMID:
19812674
44.

Mutation of FOXL2 in granulosa-cell tumors of the ovary.

Shah SP, Köbel M, Senz J, Morin RD, Clarke BA, Wiegand KC, Leung G, Zayed A, Mehl E, Kalloger SE, Sun M, Giuliany R, Yorida E, Jones S, Varhol R, Swenerton KD, Miller D, Clement PB, Crane C, Madore J, Provencher D, Leung P, DeFazio A, Khattra J, Turashvili G, Zhao Y, Zeng T, Glover JN, Vanderhyden B, Zhao C, Parkinson CA, Jimenez-Linan M, Bowtell DD, Mes-Masson AM, Brenton JD, Aparicio SA, Boyd N, Hirst M, Gilks CB, Marra M, Huntsman DG.

N Engl J Med. 2009 Jun 25;360(26):2719-29. doi: 10.1056/NEJMoa0902542. Epub 2009 Jun 10.

45.

Inter-observer reproducibility of HER2 immunohistochemical assessment and concordance with fluorescent in situ hybridization (FISH): pathologist assessment compared to quantitative image analysis.

Turashvili G, Leung S, Turbin D, Montgomery K, Gilks B, West R, Carrier M, Huntsman D, Aparicio S.

BMC Cancer. 2009 May 29;9:165. doi: 10.1186/1471-2407-9-165.

46.

A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability.

Eirew P, Stingl J, Raouf A, Turashvili G, Aparicio S, Emerman JT, Eaves CJ.

Nat Med. 2008 Dec;14(12):1384-9. doi: 10.1038/nm.1791. Epub 2008 Nov 23.

PMID:
19029987
47.

Characterization of a novel anti-fatty acid synthase (FASN) antiserum in breast tissue.

Jensen KC, Schaeffer DF, Cheang M, Montgomery K, West RB, Gilks CB, Ross D, Turashvili G, Schnitt S, van de Rijn M.

Mod Pathol. 2008 Dec;21(12):1413-20. doi: 10.1038/modpathol.2008.163. Epub 2008 Sep 26.

48.

Columnar cell lesions, mammographic density and breast cancer risk.

Turashvili G, McKinney S, Martin L, Gelmon KA, Watson P, Boyd N, Aparicio S.

Breast Cancer Res Treat. 2009 Jun;115(3):561-71. doi: 10.1007/s10549-008-0099-x. Epub 2008 Jun 28.

PMID:
18587641
49.

A case of osteoclast-like giant cell tumor of the pancreas associated with borderline mucinous cystic neoplasm.

Burkadze G, Turashvili G.

Pathol Oncol Res. 2009 Mar;15(1):129-31. doi: 10.1007/s12253-008-9053-9. Epub 2008 May 21.

PMID:
18493871
50.

Are columnar cell lesions the earliest histologically detectable non-obligate precursor of breast cancer?

Turashvili G, Hayes M, Gilks B, Watson P, Aparicio S.

Virchows Arch. 2008 Jun;452(6):589-98. doi: 10.1007/s00428-008-0609-6. Epub 2008 Apr 24. Review.

PMID:
18437416

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