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Items: 7


Cell cycle arrest in mitosis promotes interferon-induced necroptosis.

Frank T, Tuppi M, Hugle M, Dötsch V, van Wijk SJL, Fulda S.

Cell Death Differ. 2019 Feb 11. doi: 10.1038/s41418-019-0298-5. [Epub ahead of print]


Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain.

Krauskopf K, Gebel J, Kazemi S, Tuppi M, Löhr F, Schäfer B, Koch J, Güntert P, Dötsch V, Kehrloesser S.

Structure. 2018 Aug 7;26(8):1091-1100.e4. doi: 10.1016/j.str.2018.05.013. Epub 2018 Jun 28.


CHK2 sets the stage for CK1 in oocyte quality control.

Kehrloesser S, Tuppi M, Dötsch V.

Cell Death Differ. 2018 Jun;25(6):1007-1009. doi: 10.1038/s41418-018-0107-6. No abstract available.


Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63.

Tuppi M, Kehrloesser S, Coutandin DW, Rossi V, Luh LM, Strubel A, Hötte K, Hoffmeister M, Schäfer B, De Oliveira T, Greten F, Stelzer EHK, Knapp S, De Felici M, Behrends C, Klinger FG, Dötsch V.

Nat Struct Mol Biol. 2018 Mar;25(3):261-269. doi: 10.1038/s41594-018-0035-7. Epub 2018 Feb 26.


Control mechanisms in germ cells mediated by p53 family proteins.

Gebel J, Tuppi M, Krauskopf K, Coutandin D, Pitzius S, Kehrloesser S, Osterburg C, Dötsch V.

J Cell Sci. 2017 Aug 9. pii: jcs.204859. doi: 10.1242/jcs.204859. [Epub ahead of print] Review.


Intrinsic aggregation propensity of the p63 and p73 TI domains correlates with p53R175H interaction and suggests further significance of aggregation events in the p53 family.

Kehrloesser S, Osterburg C, Tuppi M, Schäfer B, Vousden KH, Dötsch V.

Cell Death Differ. 2016 Dec;23(12):1952-1960. doi: 10.1038/cdd.2016.75. Epub 2016 Jul 22.


Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.

Coutandin D, Osterburg C, Srivastav RK, Sumyk M, Kehrloesser S, Gebel J, Tuppi M, Hannewald J, Schäfer B, Salah E, Mathea S, Müller-Kuller U, Doutch J, Grez M, Knapp S, Dötsch V.

Elife. 2016 Mar 14;5. pii: e13909. doi: 10.7554/eLife.13909.

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